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347 Cruises (2,121 Cruise Departures)
58 Day Panama Canal, Chilean Fjords, Antarctica & Falklands with Seabourn
Cruise
 (1)

58 Days (57 Nights) Miami to Buenos Aires
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+5 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Exclusive Savings
Inside
-
Oceanview
$33,647
Balcony
$38,057
Suite
-
From
US$33,647
Save 552
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (2)

23 Days (22 Nights) Buenos Aires to Santiago
Cruise Line: Holland America
Ship: Oosterdam
Departures: Feb 2027 to Jan 2028
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Fare Saver
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,355
Oceanview
$4,551
Balcony
$6,472
Suite
$8,314
From
US$4,355
Save 69
Per Person
View Trip
24 Day Chile, Antarctica & Falkland Islands Cruise: Chilean Fjords, Ushuaia & Montevideo with Azamara Cruises
Cruise
 (4)

24 Days (23 Nights) Valparaiso to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Azamara Always Included
Exclusive Savings
Inside
$7,187
Oceanview
$8,438
Balcony
$10,340
Suite
$15,878
From
US$7,187
Save 172
Per Person
View Trip
18 Day Antarctica & South America with Princess
Cruise
 (7)

18 Days (17 Nights) Buenos Aires to Buenos Aires
Cruise Line: Princess
Ship: Majestic Princess
Departures: Jan 2027 to Jan 2027
Visit: Argentina, Chile, Antarctica, Falkland Islands, Uruguay
Princess Standard
Exclusive Savings
Inside
$3,072
Oceanview
-
Balcony
$4,180
Suite
$4,524
From
US$3,072
Save 52
Per Person
View Trip
66 Day South American Adventure with Oceania Cruises
Cruise
 (1)

66 Days (65 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, Barbados, Guadeloupe, Virgin Islands
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$20,133
Oceanview
$20,958
Balcony
$27,408
Suite
$38,369
From
US$20,133
Save 20,965
Per Person
View Trip
19 Day Colossal Coastlines with Regent Seven Seas
Cruise

19 Days (18 Nights) Buenos Aires to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 02 February 2027
Visit: Argentina, Chile, Antarctica, Falkland Islands, Uruguay
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,643
Suite
$17,672
From
US$16,643
Save 17,255
Per Person
View Trip
22 Day Antarctica & Chilean Fjords Cruise: Buenos Aires, Ushuaia & Santiago with Azamara Cruises
Cruise
 (3)

22 Days (21 Nights) Buenos Aires to Santiago
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 February 2027
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Azamara Always Included
Exclusive Savings
Inside
$9,491
Oceanview
$10,558
Balcony
$11,781
Suite
$18,784
From
US$9,491
Save 238
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Valparaiso to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$6,548
Oceanview
$6,839
Balcony
$8,828
Suite
$12,174
From
US$6,548
Save 6,850
Per Person
View Trip
29 Day Ultimate Antarctica & the Fjords of Southern Chile with Scenic
New ReleaseCruise

29 Days (28 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 17 February 2027
Visit: Argentina, Antarctica, Uruguay
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$70,995
Suite
$156,345
From
US$70,995
Save 2,080
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Buenos Aires to Valparaiso
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 24 January 2027
Visit: Argentina, Falkland Islands, Antarctica, Chile
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$6,065
Oceanview
$6,647
Balcony
$8,975
Suite
$13,146
From
US$6,065
Save 6,333
Per Person
View Trip
42 Day Grand South America & Antarctica Voyage with Holland America
Cruise
 (3)

42 Days (41 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Zaandam
Departure: 03 January 2027
Visit: USA, Cayman Islands, Panama, Ecuador (+6 more), Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Advantage Fare
Exclusive Savings
Inside
$10,137
Oceanview
$11,264
Balcony
$19,839
Suite
-
From
US$10,137
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (2)

23 Days (22 Nights) San Antonio to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Jan 2027 to Jan 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Fare Saver
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,452
Oceanview
$4,648
Balcony
$6,697
Suite
$8,902
From
US$4,452
Save 69
Per Person
View Trip
19 Day Antarctic Encounter with Regent Seven Seas
Cruise

19 Days (18 Nights) Buenos Aires to Lima
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 20 February 2027
Visit: Argentina, Falkland Islands, Antarctica, Chile, Peru
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,917
Suite
$19,240
From
US$34,723
Save 675
Per Person
View Trip
24 Day Antarctica & Falklands - From Punta Arenas To Buenos Aires with HX Expeditions
Cruise

24 Days (23 Nights) Santiago to Buenos Aires
Cruise Line: HX Expeditions
Ship: MS Fram
Departure: 20 March 2026
Visit: Chile, Antarctica, Falkland Islands, Argentina
Bonus Onboard Credit
Exclusive Savings
Inside
-
Oceanview
$14,837
Balcony
-
Suite
$19,775
From
US$14,837
Save 6,485
Per Person
View Trip
31 Day Chilean Fjords, Glaciers & Antarctic Wildlife Explorer with Scenic
Cruise

31 Days (30 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Visit: Chile, Argentina, Falkland Islands, South Georgia Island, Antarctica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$94,501
Suite
$125,056
From
US$94,501
Save 2,814
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Marseille to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 07 November 2027
Visit: France, Spain, Portugal, Brazil
Bonus Onboard Credit
Inside
$1,159
Oceanview
$1,279
Balcony
$1,679
Suite
-
From
US$1,159
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

24 Days (23 Nights) Rome to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 31 October 2027
Visit: Italy, Sicily, Spain, France, Portugal, Brazil
Bonus Onboard Credit
Inside
$1,589
Oceanview
$1,859
Balcony
$2,279
Suite
-
From
US$1,589
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy, France
Bonus Onboard Credit
Inside
$1,949
Oceanview
$2,209
Balcony
$2,473
Suite
$8,438
From
US$1,949
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Amalfi to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 14 November 2027
Visit: Italy, Spain, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$2,029
Oceanview
$2,471
Balcony
$2,675
Suite
$4,547
From
US$2,029
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Buenos Aires to Bari
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 31 March 2027
Visit: Argentina, Brazil, Spain, Corsica, Italy, Greece
Bonus Onboard Credit
Inside
$1,751
Oceanview
$2,171
Balcony
$2,376
Suite
$3,656
From
US$1,751
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Palermo to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 12 November 2026
Visit: Sicily, Malta, Spain, Gibraltar (+4 more), Morocco, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$1,911
Oceanview
-
Balcony
$2,531
Suite
$4,122
From
US$1,911
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Buenos Aires to Rome
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 31 March 2027
Visit: Argentina, Brazil, Spain, Corsica, Italy
Bonus Onboard Credit
Inside
$1,487
Oceanview
$1,847
Balcony
$2,087
Suite
$3,437
From
US$1,487
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Amalfi to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 13 November 2027
Visit: Italy, France, Spain, Brazil
Bonus Onboard Credit
Inside
$1,859
Oceanview
-
Balcony
-
Suite
$4,906
From
US$1,859
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise

26 Days (25 Nights) Rome to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 22 October 2027
Visit: Italy, Greece, Turkey, France, Spain, Brazil
Bonus Onboard Credit
Inside
$2,169
Oceanview
$2,464
Balcony
$2,882
Suite
$4,705
From
US$2,169
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Florence to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 10 November 2026
Visit: Italy, Sardinia, Sicily, Malta (+6 more), Spain, Gibraltar, Morocco, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$2,189
Oceanview
-
Balcony
$2,803
Suite
$4,132
From
US$2,189
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy
Bonus Onboard Credit
Inside
$1,791
Oceanview
$2,031
Balcony
$2,337
Suite
$7,750
From
US$1,791
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Genoa to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 06 November 2027
Visit: Italy, France, Spain, Portugal, Brazil
Bonus Onboard Credit
Inside
$1,234
Oceanview
$1,424
Balcony
$1,774
Suite
-
From
US$1,234
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Amalfi to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 28 October 2027
Visit: Italy, France, Spain, Brazil
Bonus Onboard Credit
Inside
$1,599
Oceanview
$1,929
Balcony
$2,197
Suite
$6,252
From
US$1,599
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Rio de Janeiro to Marseille
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 04 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy, France
Bonus Onboard Credit
Inside
$1,884
Oceanview
$2,223
Balcony
$2,369
Suite
-
From
US$1,884
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Cagliari to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 11 November 2026
Visit: Sardinia, Sicily, Malta, Spain (+5 more), Gibraltar, Morocco, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$2,004
Oceanview
$2,379
Balcony
$2,641
Suite
-
From
US$2,004
Per Person
View Trip
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South & Central America Cruises

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Travel Styles

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Cities

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Routes

Cruises from Baltra Island to Baltra Island Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Trieste Cruises from Barcelona to Athens Cruises from Barcelona to Lisbon Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Trieste Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Athens Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Cristobal Island to San Cristobal Island Cruises from San Juan to Miami Cruises from San Juan to San Juan Cruises from Santiago to Buenos Aires Cruises from Santiago to Santiago Cruises from Santos to Santos Cruises from Sao Paulo to Sao Paulo Cruises from Tahiti to Tahiti Cruises from Ushuaia to Ushuaia Cruises from Venice to Athens Cruises from Venice to Barcelona Cruises from Venice to Rome

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from Germany to England Cruises from Canada to Japan Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from Chile to USA Cruises from France to Brazil Cruises from Brazil to France Cruises from England to Germany Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Argentina to Brazil Cruises from USA to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Peru to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from USA to Dominican Republic Cruises from England to Norway Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to Chile Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Italy Cruises from USA to Japan Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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