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Cruises from Rome to Lisbon

Are you looking for a cruise from Rome to Lisbon? October, November and April are the most popular months to cruise between Rome and Lisbon and there are 51 departures available from thirteen of the world's leading cruise lines.
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27 Cruises (51 Departures)
27 Cruises (51 Departures)
Departures
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Duration
7 Days
22 Days
Ship Size
Ship Features
Operators
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Price
$500pp
$57,798pp
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11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sirena
Departure: 04 January 2027
Visits: Italy, France, Spain, Portugal
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,412
Suite
$4,225
From (Per Person)
US$3,412
Save 7,086
Per Person
View Trip
12 Day Mediterranean Rivieras with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Operator: Emerald Cruises
Ship: Emerald Azzurra
Departure: 27 October 2026
Visits: Italy, Corsica, Spain, Morocco, Portugal
Exclusive Savings
Oceanview
$8,790
Suite
$11,711
From (Per Person)
US$8,790
Save 855
Per Person
View Trip
10 Day Western Mediterranean Cruise From Rome To Lisbon with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Lisbon
Operator: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 October 2027
Visits: Italy, France, Spain, Portugal
Inside
$1,959
Oceanview
$2,489
Balcony
$2,859
Suite
$3,709
From (Per Person)
US$1,959
Per Person
View Trip
17 Day Rome to Lisbon with Silversea
Cruise
 (1)

17 Days (16 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visits: Italy, Sicily, Tunisia, Sardinia +4 more, Spain, Gibraltar, Morocco, Portugal
Balcony
$8,700
Suite
$14,300
From (Per Person)
US$8,700
Per Person
View Trip
20 Day Mediterranean Isles Legacy with Oceania Cruises
Cruise
 (1)

20 Days (19 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sirena
Departure: 02 December 2026
Visits: Italy, Corsica, France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,099
Suite
$17,949
From (Per Person)
US$9,099
Save 9,099
Per Person
View Trip
21 Day Summer Splendor with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Nautica
Departure: 27 June 2027
Visits: Italy, Sicily, Sardinia, Corsica +5 more, France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Exclusive Savings
Inside
$6,499
Oceanview
$6,649
Balcony
$11,049
Suite
$14,599
From (Per Person)
US$6,499
Save 6,499
Per Person
View Trip
11 Day Spain Intensive Cruise: Palma, Malaga & Seville with Azamara Cruises
Cruise
 (6)

11 Days (10 Nights) Rome to Lisbon
Operator: Azamara
Ship: Azamara Quest
Departure: 29 April 2028
Visits: Italy, Sardinia, Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$3,087
Oceanview
$3,362
Balcony
$4,132
Suite
$5,842
From (Per Person)
US$3,087
Save 162
Per Person
View Trip
11 Day Roman Holiday with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Marina
Departure: 27 November 2027
Visits: Italy, Corsica, France, Spain, Gibraltar, Portugal
Your World Inclusions
Exclusive Savings
Inside
$2,949
Oceanview
$3,749
Balcony
$4,399
Suite
$6,399
From (Per Person)
US$2,949
Save 2,949
Per Person
View Trip
18 Day Mediterranean & Iberian New Year Cruise: Italy, Spain & Morocco with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Lisbon
Operator: Azamara
Ship: Azamara Onward
Departure: 22 December 2026
Visits: Italy, Spain, Morocco, Portugal
Azamara Always Included
Inside
-
Oceanview
$6,009
Balcony
$6,809
Suite
$11,249
From (Per Person)
US$6,009
Per Person
View Trip
16 Day Italy, France & Spain Cruise: Rome, Barcelona & Seville with Azamara Cruises
Cruise
 (5)

16 Days (15 Nights) Rome to Lisbon
Operator: Azamara
Ship: Azamara Journey
Departure: 04 December 2027
Visits: Italy, France, Spain, Gibraltar, Portugal
Exclusive Savings
Inside
$3,733
Oceanview
$4,464
Balcony
$5,595
Suite
$8,321
From (Per Person)
US$3,733
Save 196
Per Person
View Trip
13 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Nova
Departure: 21 November 2027
Visits: Italy, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$5,700
Suite
$11,800
From (Per Person)
US$5,700
Save 3,800
Per Person
View Trip
22 Day A Journey Across The Mediterranean’s Edge & Into The Atlantic with Explora Journeys
Cruise
 (1)

22 Days (21 Nights) Rome to Lisbon
Operator: Explora Journeys
Ship: Explora II
Departure: 02 February 2027
Visits: Italy, Sicily, Tunisia, Algeria, Spain, Morocco, Portugal
Suite
$10,745
From (Per Person)
US$10,745
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise

7 Days (6 Nights) Rome to Lisbon
Operator: MSC Cruises
Ship: MSC Sinfonia
Departure: 27 May 2027
Visits: Italy, France, Spain, Portugal
Inside
$549
Oceanview
-
Balcony
-
Suite
-
From (Per Person)
US$549
Per Person
View Trip
15 Day Spain, Portugal & the Mediterranean with Viking Cruises
Cruise

15 Days (14 Nights) Rome to Lisbon
Operator: Viking
Ships: Viking Astrea, Viking Jupiter +10 more, Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela
Departures: Jan 2027 to Aug 2029
Visits: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$6,198
Suite
$9,098
From (Per Person)
US$6,198
Save 1,200
Per Person
View Trip
12 Day Treasures of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Lisbon
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Visits: Italy, Sicily, Malta, Tunisia, Algeria, Spain, Portugal
Exclusive Savings
Balcony
$14,636
Suite
$20,081
From (Per Person)
US$14,636
Save 3,124
Per Person
View Trip
8 Day Bolero Breeze with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 13 November 2028
Visits: Italy, Spain, Portugal
Exclusive Savings
Balcony
$6,249
Suite
$6,949
From (Per Person)
US$6,249
Save 11,249
Per Person
View Trip
10 Day Caesars & Conquistadors with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Vista
Departure: 15 June 2027
Visits: Italy, Monaco, Spain, Gibraltar, Portugal
Your World Inclusions
Exclusive Savings
Balcony
$4,399
Suite
$6,799
From (Per Person)
US$4,399
Save 4,399
Per Person
View Trip
11 Day Renaissance To Algarve Sun with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sonata
Departure: 08 April 2028
Visits: Italy, France, Spain, Gibraltar, Portugal
Your World Inclusions
Exclusive Savings
Balcony
$5,699
Suite
$7,699
From (Per Person)
US$5,699
Save 5,699
Per Person
View Trip
18 Day Civitavecchia to Lisbon with Crystal Cruises
New ReleaseCruise

18 Days (17 Nights) Rome to Lisbon
Operator: Crystal
Ship: Crystal Symphony
Departure: 01 October 2027
Visits: Italy, Sicily, Malta, Tunisia +4 more, Monaco, Corsica, Spain, Portugal
Exclusive Savings
Oceanview
$7,757
Balcony
$9,950
Suite
$9,863
From (Per Person)
US$7,757
Save 2,443
Per Person
View Trip
17 Day Riviera Yacht Harbors Of France & Spain with Seabourn
Cruise

17 Days (16 Nights) Rome to Lisbon
Operator: Seabourn
Ship: Seabourn Ovation
Departure: 11 November 2028
Visits: Italy, Monaco, France, Spain, Morocco, Portugal
Balcony
$11,598
Suite
$18,898
From (Per Person)
US$11,598
Per Person
View Trip
11 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise

11 Days (10 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Spirit
Departure: 22 November 2027
Visits: Italy, Spain, Morocco, Portugal
Exclusive Savings
Oceanview
$4,380
Balcony
$5,220
Suite
$4,680
From (Per Person)
US$4,380
Save 2,920
Per Person
View Trip
15 Day Western Mediterranean & Iberia: Italy, France & Spain with Holland America
Cruise

15 Days (14 Nights) Rome to Lisbon
Operator: Holland America
Ship: Zuiderdam
Departure: 02 April 2028
Visits: Italy, France, Gibraltar, Spain, Morocco, Portugal
Book Early & Have It All Fare
Inside
-
Oceanview
-
Balcony
$3,401
Suite
-
From (Per Person)
US$3,401
Per Person
View Trip
11 Day Culinary Wonders with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 August 2027
Visits: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$8,649
Suite
$9,899
From (Per Person)
US$8,649
Save 14,649
Per Person
View Trip
18 Day Eternal Cities with Regent Seven Seas
Cruise

18 Days (17 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Explorer
Departure: 11 July 2028
Visits: Italy, Monaco, France, Spain, Gibraltar, Portugal
Exclusive Savings
Balcony
-
Suite
$23,399
From (Per Person)
US$23,399
Save 34,399
Per Person
View Trip
14 Day Italia To Iberian Treasures with Oceania Cruises
Cruise

14 Days (13 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sonata
Departure: 19 October 2028
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, Portugal
Your World Inclusions
Exclusive Savings
Balcony
$6,599
Suite
$9,549
From (Per Person)
US$6,599
Save 6,599
Per Person
View Trip
8 Day Spellbinding Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 31 October 2027
Visits: Italy, France, Spain, Gibraltar, Portugal
Exclusive Savings
Balcony
$4,299
Suite
$5,699
From (Per Person)
US$4,299
Save 9,299
Per Person
View Trip
15 Day Rome to Lisbon with Silversea
Cruise

15 Days (14 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Visits: Italy, Malta, Sicily, Tunisia, Sardinia, Spain, Portugal
Oceanview
$5,150
Balcony
$6,350
Suite
$15,900
From (Per Person)
US$5,150
Per Person
View Trip
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