Home > Cruises > Europe Cruises > Mediterranean Cruises > Cruises from Rome to Lisbon

Cruises from Rome to Lisbon

Are you looking for a cruise from Rome to Lisbon? October, November and April are the most popular months to cruise between Rome and Lisbon and there are 50 departures available from twelve of the world's leading cruise lines.
Filter Results
27 Cruises (50 Departures)
27 Cruises (50 Departures)
Departures
Show More...
Duration
8 Days
22 Days
Ship Size
Ship Features
Operators
Show More...
Price
$3,200pp
$43,470pp
Countries
Show More...
16 Day Italy, France & Spain Cruise: Rome, Barcelona & Seville with Azamara Cruises
Cruise
 (6)

16 Days (15 Nights) Rome to Lisbon
Operator: Azamara
Ship: Azamara Journey
Departure: 04 December 2027
Visits: Italy, France, Spain, Gibraltar, Portugal
Exclusive Savings
Inside
$5,167
Oceanview
$6,173
Balcony
$7,737
Suite
$11,489
From (Per Person)
A$5,167
Save 342
Per Person
View Trip
11 Day Spain Intensive Cruise: Palma, Malaga & Seville with Azamara Cruises
Cruise
 (6)

11 Days (10 Nights) Rome to Lisbon
Operator: Azamara
Ship: Azamara Quest
Departure: 29 April 2028
Visits: Italy, Sardinia, Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$4,654
Oceanview
$5,064
Balcony
$6,218
Suite
$8,778
From (Per Person)
A$4,654
Save 315
Per Person
View Trip
21 Day Summer Splendor with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Nautica
Departure: 27 June 2027
Visits: Italy, Sicily, Sardinia, Corsica +5 more, France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Exclusive Savings
Inside
$9,084
Oceanview
$9,298
Balcony
$15,671
Suite
$20,317
From (Per Person)
A$9,084
Save 2,196
Per Person
View Trip
22 Day A Journey Across The Mediterranean’s Edge & Into The Atlantic with Explora Journeys
Cruise
 (1)

22 Days (21 Nights) Rome to Lisbon
Operator: Explora Journeys
Ship: Explora II
Departure: 02 February 2027
Visits: Italy, Sicily, Tunisia, Algeria, Spain, Morocco, Portugal
Exclusive Savings
Suite
$24,456
From (Per Person)
A$24,456
Save 499
Per Person
View Trip
10 Day Western Mediterranean Cruise From Rome To Lisbon with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Lisbon
Operator: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 October 2027
Visits: Italy, France, Spain, Portugal
Just Cruise Fare
Exclusive Savings
Inside
$3,208
Oceanview
$4,027
Balcony
$4,474
Suite
$5,784
From (Per Person)
A$3,208
Per Person
View Trip
11 Day Roman Holiday with Oceania Cruises
Cruise
 (4)

11 Days (10 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Marina
Departure: 27 November 2027
Visits: Italy, Corsica, France, Spain, Gibraltar, Portugal
Your World Inclusions
Exclusive Savings
Inside
$4,027
Oceanview
$5,113
Balcony
$5,986
Suite
$8,693
From (Per Person)
A$4,027
Save 2,083
Per Person
View Trip
20 Day Mediterranean Isles Legacy with Oceania Cruises
Cruise
 (1)

20 Days (19 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sirena
Departure: 02 December 2026
Visits: Italy, Corsica, France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,991
Suite
-
From (Per Person)
A$12,991
Save 2,319
Per Person
View Trip
13 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Nova
Departure: 21 November 2027
Visits: Italy, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$8,183
Suite
$11,564
From (Per Person)
A$8,183
Save 3,667
Per Person
View Trip
18 Day Mediterranean & Iberian New Year Cruise: Italy, Spain & Morocco with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Lisbon
Operator: Azamara
Ship: Azamara Onward
Departure: 22 December 2026
Visits: Italy, Spain, Morocco, Portugal
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$15,800
From (Per Person)
A$15,800
Save 279
Per Person
View Trip
12 Day Mediterranean Rivieras with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Operator: Emerald Cruises
Ship: Emerald Azzurra
Departure: 27 October 2026
Visits: Italy, Corsica, Spain, Morocco, Portugal
Exclusive Savings
Oceanview
-
Balcony
-
Suite
$17,247
From (Per Person)
A$17,247
Save 3,318
Per Person
View Trip
10 Day Spain's Southern Coast & Riviera Gems with Seabourn
Cruise
 (1)

10 Days (9 Nights) Rome to Lisbon
Operator: Seabourn
Ship: Seabourn Quest
Departure: 01 November 2026
Visits: Italy, Corsica, Sardinia, Spain, Portugal
Exclusive Savings
Oceanview
$10,496
Balcony
$13,436
Suite
$20,100
From (Per Person)
A$10,496
Save 202
Per Person
View Trip
11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sirena
Departure: 04 January 2027
Visits: Italy, France, Spain, Portugal
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,663
Suite
$5,641
From (Per Person)
A$4,663
Save 5,277
Per Person
View Trip
8 Day Spellbinding Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 31 October 2027
Visits: Italy, France, Spain, Gibraltar, Portugal
Exclusive Savings
Balcony
$5,793
Suite
$6,601
From (Per Person)
A$5,793
Save 6,727
Per Person
View Trip
13 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise

13 Days (12 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Shadow
Departure: 12 November 2028
Visits: Italy, France, Spain, Portugal
Exclusive Savings
Oceanview
$8,624
Balcony
$10,584
Suite
$14,210
From (Per Person)
A$8,624
Save 3,676
Per Person
View Trip
15 Day Spain, Portugal & the Mediterranean with Viking Cruises
Cruise

15 Days (14 Nights) Rome to Lisbon
Operator: Viking
Ships: Viking Astrea, Viking Jupiter +10 more, Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela
Departures: Feb 2027 to Aug 2029
Visits: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$10,775
Suite
$15,479
From (Per Person)
A$10,775
Save 366
Per Person
View Trip
15 Day Western Mediterranean & Iberia: Italy, France & Spain with Holland America
Cruise

15 Days (14 Nights) Rome to Lisbon
Operator: Holland America
Ship: Zuiderdam
Departure: 02 April 2028
Visits: Italy, France, Gibraltar, Spain, Morocco, Portugal
Book Early & Have It All Fare Option
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,092
Suite
-
From (Per Person)
A$5,092
Per Person
View Trip
11 Day Renaissance To Algarve Sun with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sonata
Departure: 08 April 2028
Visits: Italy, France, Spain, Gibraltar, Portugal
Your World Inclusions
Exclusive Savings
Balcony
$7,727
Suite
$10,433
From (Per Person)
A$7,727
Save 2,223
Per Person
View Trip
15 Day Rome to Lisbon with Silversea
Cruise

15 Days (14 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Visits: Italy, Malta, Sicily, Tunisia, Sardinia, Spain, Portugal
Exclusive Savings
Oceanview
$7,497
Balcony
$9,163
Suite
$18,130
From (Per Person)
A$7,497
Save 153
Per Person
View Trip
18 Day Eternal Cities with Regent Seven Seas
Cruise

18 Days (17 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Explorer
Departure: 11 July 2028
Visits: Italy, Monaco, France, Spain, Gibraltar, Portugal
Exclusive Savings
Balcony
-
Suite
$32,954
From (Per Person)
A$32,954
Save 10,516
Per Person
View Trip
12 Day Treasures of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Lisbon
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Visits: Italy, Sicily, Malta, Tunisia, Algeria, Spain, Portugal
Exclusive Savings
Balcony
$21,417
Suite
$27,484
From (Per Person)
A$21,417
Save 4,393
Per Person
View Trip
14 Day Italia To Iberian Treasures with Oceania Cruises
Cruise

14 Days (13 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sonata
Departure: 19 October 2028
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, Portugal
Your World Inclusions
Exclusive Savings
Balcony
$8,951
Suite
$12,938
From (Per Person)
A$8,951
Save 2,259
Per Person
View Trip
17 Day Riviera Yacht Harbors Of France & Spain with Seabourn
Cruise

17 Days (16 Nights) Rome to Lisbon
Operator: Seabourn
Ship: Seabourn Ovation
Departure: 11 November 2028
Visits: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$16,398
Suite
$29,138
From (Per Person)
A$16,398
Save 300
Per Person
View Trip
8 Day Bolero Breeze with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 13 November 2028
Visits: Italy, Spain, Portugal
Exclusive Savings
Balcony
$7,902
Suite
$8,784
From (Per Person)
A$7,902
Save 6,628
Per Person
View Trip
11 Day Culinary Wonders with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 August 2027
Visits: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$12,804
Suite
$13,490
From (Per Person)
A$12,804
Save 6,926
Per Person
View Trip
11 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise

11 Days (10 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Spirit
Departure: 22 November 2027
Visits: Italy, Spain, Morocco, Portugal
Exclusive Savings
Oceanview
$6,076
Balcony
$6,664
Suite
$6,370
From (Per Person)
A$6,076
Save 3,624
Per Person
View Trip
18 Day Civitavecchia to Lisbon with Crystal Cruises
New ReleaseCruise

18 Days (17 Nights) Rome to Lisbon
Operator: Crystal
Ship: Crystal Symphony
Departure: 01 October 2027
Visits: Italy, Sicily, Malta, Tunisia +4 more, Monaco, Corsica, Spain, Portugal
Exclusive Savings
Oceanview
$11,591
Balcony
$15,715
Suite
$16,154
From (Per Person)
A$11,591
Save 3,909
Per Person
View Trip
10 Day Caesars & Conquistadors with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Vista
Departure: 15 June 2027
Visits: Italy, Monaco, Spain, Gibraltar, Portugal
Your World Inclusions
Exclusive Savings
Balcony
$6,028
Suite
$8,429
From (Per Person)
A$6,028
Save 2,832
Per Person
View Trip
Results: 27 results

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Luxury Cruises Short Cruise Breaks

Countries

Albania Colombia Corsica Croatia Cyprus Egypt England France Gibraltar Italy Malta Mexico Monaco Montenegro Morocco Portugal Sardinia Sicily Spain Tunisia Turkey USA

Cities

Cruises from Rome

Routes

Cruises from Rome to Lisbon

Country Routes

Cruises from Italy to Portugal

Cruise Lines Exploring The Med

APT Med Cruises Azamara Med Cruises Celebrity Med Cruises Celestyal Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises P&O (UK) Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises
© 2010-2026. Global Journeys.
    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations