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Cruises from Rome to Lisbon

Are you looking for a cruise from Rome to Lisbon? November is the most popular month to cruise between Rome and Lisbon and there are 27 departures available from ten of the world's leading cruise lines.
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21 Cruises (27 Cruise Departures)
12 Day Mediterranean Rivieras with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 27 October 2026
Countries Visited: Italy, Corsica, Spain, Morocco (+1 more), Portugal
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$8,465
BALCONY
-
SUITE
$11,678
Save (per person) 9,125
From (per person) 8,465
View Trip
20 Day Mediterranean Isles Legacy with Oceania Cruises
Cruise
 (3)

20 Days (19 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 December 2026
Countries Visited: Italy, Corsica, France, Spain (+3 more), Gibraltar, Morocco, Portugal
Exclusive Deal
INSIDE
$4,999
OCEANVIEW
$5,499
BALCONY
$8,199
SUITE
$11,499
Save (per person) 4,999
From (per person) 4,999
View Trip
11 Day Western Mediterranean From Rome To Lisbon with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 18 November 2025
Countries Visited: Italy, France, Spain, Portugal
INSIDE
$1,771
OCEANVIEW
$1,880
BALCONY
$2,281
SUITE
$2,981
From (per person) 1,771
View Trip
13 Day Western Mediterranean From Rome To Lisbon with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 01 November 2025
Countries Visited: Italy, Sicily, Spain, Morocco (+1 more), Portugal
INSIDE
$1,011
OCEANVIEW
$1,482
BALCONY
$1,531
SUITE
$1,651
From (per person) 1,011
View Trip
21 Day Empires & Explorers with Oceania Cruises
Cruise
 (3)

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 18 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+5 more), Monaco, France, Spain, Portugal, Morocco
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,199
SUITE
-
Save (per person) 9,199
From (per person) 9,199
View Trip
10 Day Caesars & Conquistadors with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 15 June 2027
Countries Visited: Italy, Monaco, Spain, Gibraltar (+1 more), Portugal
Flash SaleExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$4,599
SUITE
$6,599
Save (per person) 4,599
From (per person) 4,599
View Trip
18 Day Mediterranean & Iberian New Year Cruise: Italy, Spain & Morocco with Azamara Cruises
Cruise
 (3)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Countries Visited: Italy, Spain, Morocco, Portugal
INSIDE
$3,929
OCEANVIEW
$4,509
BALCONY
$5,869
SUITE
$9,069
From (per person) 3,929
View Trip
15 Day Spain, Portugal & the Mediterranean with Viking Cruises
Cruise

15 Days (14 Nights) Rome to Lisbon
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Mira, Viking Neptune
Departures: Nov 2026 to Sep 2027
Countries Visited: Italy, Monaco, France, Spain (+2 more), Morocco, Portugal
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$5,948
SUITE
$8,498
Save (per person) 700
From (per person) 5,948
View Trip
18 Day Italy, Spain & Portugal Cruise: Florence, Nice & Seville with Azamara Cruises
Cruise
 (3)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 30 October 2027
Countries Visited: Italy, Monaco, France, Spain (+2 more), Gibraltar, Portugal
INSIDE
$4,969
OCEANVIEW
$5,709
BALCONY
$7,149
SUITE
$10,189
From (per person) 4,969
View Trip
21 Day Rome to Lisbon with Silversea
Cruise

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Muse
Departure: 31 July 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+5 more), Sardinia, Spain, Gibraltar, Morocco, Portugal
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$10,600
BALCONY
$12,000
SUITE
$16,200
From (per person) 10,600
View Trip
13 Day Rome to Lisbon with Silversea
Cruise

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 November 2025
Countries Visited: Italy, Monaco, France, Spain (+1 more), Portugal
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,400
From (per person) 10,400
View Trip
11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2027
Countries Visited: Italy, France, Spain, Portugal
Flash SaleExclusive Deal
INSIDE
$2,699
OCEANVIEW
$2,999
BALCONY
$4,499
SUITE
$6,199
Save (per person) 2,699
From (per person) 2,699
View Trip
15 Day Rome to Lisbon with Silversea
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Countries Visited: Italy, Malta, Sicily, Tunisia (+3 more), Sardinia, Spain, Portugal
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$9,500
BALCONY
$10,200
SUITE
$16,800
From (per person) 9,500
View Trip
11 Day Western Mediterranean: Idyllic Isles & Hidden Gems with Holland America
Cruise
 (2)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 24 May 2026
Countries Visited: Italy, Sicily, Sardinia, Spain (+2 more), Gibraltar, Portugal
Exclusive Deal
INSIDE
$1,809
OCEANVIEW
$1,959
BALCONY
$2,659
SUITE
$3,709
From (per person) 1,809
View Trip
10 Day Spain's Southern Coast & Riviera Gems with Seabourn
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 01 November 2026
Countries Visited: Italy, Corsica, Sardinia, Spain (+1 more), Portugal
Sail Into Savings
INSIDE
-
OCEANVIEW
$5,698
BALCONY
$7,398
SUITE
$13,498
From (per person) 5,698
View Trip
17 Day Rome to Lisbon with Silversea
Cruise

17 Days (16 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Countries Visited: Italy, Sicily, Tunisia, Sardinia (+4 more), Spain, Gibraltar, Morocco, Portugal
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,200
From (per person) 9,200
View Trip
15 Day Rivieras, Minarets & More with Oceania Cruises
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 28 April 2026
Countries Visited: Italy, France, Spain, Morocco (+1 more), Portugal
Exclusive DealFlash Sale
INSIDE
$4,999
OCEANVIEW
$6,049
BALCONY
$5,747
SUITE
$7,932
Save (per person) 4,999
From (per person) 4,999
View Trip
10 Day Western Mediterranean From Rome To Lisbon with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sky
Departure: 14 October 2025
Countries Visited: Italy, France, Spain, Portugal
INSIDE
$1,119
OCEANVIEW
$1,249
BALCONY
$2,269
SUITE
$4,969
From (per person) 1,119
View Trip
11 Day Tuscan Summer with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 July 2026
Countries Visited: Italy, France, Spain, Gibraltar (+1 more), Portugal
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$9,399
SUITE
$11,199
Save (per person) 14,799
From (per person) 9,399
View Trip
11 Day Culinary Wonders with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 August 2027
Countries Visited: Italy, Monaco, France, Spain (+2 more), Morocco, Portugal
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$8,799
SUITE
$9,949
Save (per person) 14,799
From (per person) 8,799
View Trip
12 Day Treasures of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Countries Visited: Italy, Sicily, Malta, Tunisia (+3 more), Algeria, Spain, Portugal
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$14,550
SUITE
$22,950
Save (per person) 15,040
From (per person) 14,550
View Trip
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