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Cruises from Rome to Lisbon

Are you looking for a cruise from Rome to Lisbon? November is the most popular month to cruise between Rome and Lisbon and there are 40 departures available from ten of the world's leading cruise lines.
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21 Days
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$29,198pp
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21 Cruises (40 Cruise Departures)
10 Day Spain's Southern Coast & Riviera Gems with Seabourn
Cruise
 (1)

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 01 November 2026
Visit: Italy, Corsica, Sardinia, Spain, Portugal
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,033
Suite
$14,653
From
US$9,033
Save 166
Per Person
View Trip
11 Day Tuscan Summer with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 July 2026
Visit: Italy, France, Spain, Gibraltar, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,328
Suite
$15,210
From
US$14,328
Save 14,870
Per Person
View Trip
11 Day Culinary Wonders with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 August 2027
Visit: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,389
Suite
$12,516
From
US$11,389
Save 11,809
Per Person
View Trip
17 Day Rome to Lisbon with Silversea
Cruise
 (1)

17 Days (16 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visit: Italy, Sicily, Tunisia, Sardinia (+4 more), Spain, Gibraltar, Morocco, Portugal
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$8,400
Suite
$14,300
From
US$8,400
Per Person
View Trip
12 Day Treasures of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Visit: Italy, Sicily, Malta, Tunisia, Algeria, Spain, Portugal
Preferred Plus Fare + Air Credit
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,697
Suite
$20,979
From
US$15,697
Save 2,063
Per Person
View Trip
10 Day Western Mediterranean Cruise From Rome To Lisbon with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 October 2027
Visit: Italy, France, Spain, Portugal
Exclusive Savings
Inside
$2,160
Oceanview
$2,694
Balcony
$3,334
Suite
$4,110
From
US$2,160
Save 59
Per Person
View Trip
10 Day Caesars & Conquistadors with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 15 June 2027
Visit: Italy, Monaco, Spain, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,293
Suite
$6,669
From
US$4,293
Save 4,505
Per Person
View Trip
18 Day Mediterranean & Iberian New Year Cruise: Italy, Spain & Morocco with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Visit: Italy, Spain, Morocco, Portugal
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$5,438
Balcony
-
Suite
$10,424
From
US$5,438
Save 121
Per Person
View Trip
12 Day Mediterranean Rivieras with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 27 October 2026
Visit: Italy, Corsica, Spain, Morocco, Portugal
Preferred Plus Fare + Air Credit
Select Fare
Exclusive Savings
Inside
-
Oceanview
$8,559
Balcony
-
Suite
$11,392
From
US$8,559
Save 1,086
Per Person
View Trip
13 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Nova
Departure: 21 November 2027
Visit: Italy, France, Spain, Morocco, Portugal
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,210
Suite
$10,210
From
US$7,210
Save 3,090
Per Person
View Trip
11 Day Western Mediterranean: Idyllic Isles & Hidden Gems with Holland America
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 24 May 2026
Visit: Italy, Sicily, Sardinia, Spain, Gibraltar, Portugal
Have It All Fare Option
Inside
$2,199
Oceanview
$2,199
Balcony
$2,949
Suite
$4,075
From
US$2,199
Per Person
View Trip
11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2027
Visit: Italy, France, Spain, Portugal
Your World Inclusions
Exclusive Savings
Inside
$1,755
Oceanview
$1,950
Balcony
$3,083
Suite
$4,238
From
US$1,755
Save 3,643
Per Person
View Trip
21 Day Summer Splendor with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 June 2027
Visit: Italy, Sicily, Sardinia, Corsica (+5 more), France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$5,922
Oceanview
$6,456
Balcony
$10,433
Suite
$14,070
From
US$5,922
Save 6,176
Per Person
View Trip
15 Day Italy, French Riviera & Spain Collectors' Voyage with Holland America
Cruise
 (3)

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 26 July 2026
Visit: Italy, France, Gibraltar, Spain, Morocco, Portugal
Fare Saver
Inside
$2,064
Oceanview
$2,194
Balcony
-
Suite
-
From
US$2,064
Per Person
View Trip
16 Day Italy, France & Spain Cruise: Rome, Barcelona & Seville with Azamara Cruises
Cruise
 (3)

16 Days (15 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 December 2027
Visit: Italy, France, Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$3,561
Oceanview
$4,454
Balcony
$5,608
Suite
$8,392
From
US$3,561
Save 68
Per Person
View Trip
11 Day Roman Holiday with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 27 November 2027
Visit: Italy, Corsica, France, Spain, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,741
Oceanview
$3,565
Balcony
$4,293
Suite
$6,233
From
US$2,741
Save 2,857
Per Person
View Trip
11 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 22 November 2027
Visit: Italy, Spain, Morocco, Portugal
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$5,440
Balcony
$6,000
Suite
$5,520
From
US$5,440
Save 1,360
Per Person
View Trip
18 Day Italy, Spain & Portugal Cruise: Florence, Nice & Seville with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 30 October 2027
Visit: Italy, Monaco, France, Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$10,894
Oceanview
$11,961
Balcony
$14,057
Suite
$15,221
From
US$10,894
Save 295
Per Person
View Trip
20 Day Mediterranean Isles Legacy with Oceania Cruises
Cruise
 (1)

20 Days (19 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 December 2026
Visit: Italy, Corsica, France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$5,090
Oceanview
$5,381
Balcony
$8,534
Suite
$11,492
From
US$5,090
Save 5,308
Per Person
View Trip
15 Day Rome to Lisbon with Silversea
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Visit: Italy, Malta, Sicily, Tunisia, Sardinia, Spain, Portugal
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$8,640
Balcony
$9,270
Suite
$17,400
From
US$8,640
Save 960
Per Person
View Trip
15 Day Spain, Portugal & the Mediterranean with Viking Cruises
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Libra (+8 more), Viking Lyra, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela
Departures: Jan 2027 to Sep 2028
Visit: Italy, Monaco, France, Spain, Morocco, Portugal
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$5,998
Suite
$9,398
From
US$5,998
Save 400
Per Person
View Trip
Results: 21 results

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