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Cruises from Rome to Lisbon

Are you looking for a cruise from Rome to Lisbon? October, November and April are the most popular months to cruise between Rome and Lisbon and there are 49 departures available from twelve of the world's leading cruise lines.
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26 Cruises (49 Departures)
26 Cruises (49 Departures)
Departures
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Duration
8 Days
22 Days
Ship Size
Ship Features
Operators
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Price
$3,200pp
$43,470pp
Countries
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16 Day Italy, France & Spain Cruise: Rome, Barcelona & Seville with Azamara Cruises
Cruise
 (5)

16 Days (15 Nights) Rome to Lisbon
Operator: Azamara
Ship: Azamara Journey
Departure: 04 December 2027
Visits: Italy, France, Spain, Gibraltar, Portugal
Exclusive Savings
Inside
$5,121
Oceanview
$6,126
Balcony
$7,662
Suite
$11,386
From (Per Person)
A$5,121
Save 338
Per Person
View Trip
21 Day Summer Splendor with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Nautica
Departure: 27 June 2027
Visits: Italy, Sicily, Sardinia, Corsica +5 more, France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Exclusive Savings
Inside
$9,084
Oceanview
$9,298
Balcony
$15,399
Suite
$20,317
From (Per Person)
A$9,084
Save 2,196
Per Person
View Trip
18 Day Mediterranean & Iberian New Year Cruise: Italy, Spain & Morocco with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Lisbon
Operator: Azamara
Ship: Azamara Onward
Departure: 22 December 2026
Visits: Italy, Spain, Morocco, Portugal
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,332
Suite
$15,388
From (Per Person)
A$9,332
Save 147
Per Person
View Trip
12 Day Mediterranean Rivieras with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Operator: Emerald Cruises
Ship: Emerald Azzurra
Departure: 27 October 2026
Visits: Italy, Corsica, Spain, Morocco, Portugal
Exclusive Savings
Oceanview
-
Suite
$17,247
From (Per Person)
A$17,247
Save 3,318
Per Person
View Trip
17 Day Rome to Lisbon with Silversea
Cruise
 (1)

17 Days (16 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visits: Italy, Sicily, Tunisia, Sardinia +4 more, Spain, Gibraltar, Morocco, Portugal
Exclusive Savings
Balcony
$13,181
Suite
$21,658
From (Per Person)
A$13,181
Save 269
Per Person
View Trip
22 Day A Journey Across The Mediterranean’s Edge & Into The Atlantic with Explora Journeys
Cruise
 (1)

22 Days (21 Nights) Rome to Lisbon
Operator: Explora Journeys
Ship: Explora II
Departure: 02 February 2027
Visits: Italy, Sicily, Tunisia, Algeria, Spain, Morocco, Portugal
Exclusive Savings
Suite
$17,116
From (Per Person)
A$17,116
Save 349
Per Person
View Trip
11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sirena
Departure: 04 January 2027
Visits: Italy, France, Spain, Portugal
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,660
Suite
$4,523
From (Per Person)
A$3,660
Save 5,800
Per Person
View Trip
10 Day Western Mediterranean Cruise From Rome To Lisbon with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Lisbon
Operator: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 October 2027
Visits: Italy, France, Spain, Portugal
Just Cruise Fare
Exclusive Savings
Inside
$3,208
Oceanview
$4,027
Balcony
$4,474
Suite
$5,814
From (Per Person)
A$3,208
Per Person
View Trip
11 Day Spain Intensive Cruise: Palma, Malaga & Seville with Azamara Cruises
Cruise
 (6)

11 Days (10 Nights) Rome to Lisbon
Operator: Azamara
Ship: Azamara Quest
Departure: 29 April 2028
Visits: Italy, Sardinia, Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$4,440
Oceanview
$4,831
Balcony
$5,920
Suite
$8,359
From (Per Person)
A$4,440
Save 299
Per Person
View Trip
20 Day Mediterranean Isles Legacy with Oceania Cruises
Cruise
 (1)

20 Days (19 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sirena
Departure: 02 December 2026
Visits: Italy, Corsica, France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,623
Suite
-
From (Per Person)
A$12,623
Save 2,307
Per Person
View Trip
11 Day Roman Holiday with Oceania Cruises
Cruise
 (4)

11 Days (10 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Marina
Departure: 27 November 2027
Visits: Italy, Corsica, France, Spain, Gibraltar, Portugal
Your World Inclusions
Exclusive Savings
Inside
$4,027
Oceanview
$5,113
Balcony
$5,986
Suite
$8,693
From (Per Person)
A$4,027
Save 2,083
Per Person
View Trip
13 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Nova
Departure: 21 November 2027
Visits: Italy, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$13,328
Suite
$13,250
From (Per Person)
A$13,250
Save 3,650
Per Person
View Trip
15 Day Rome to Lisbon with Silversea
Cruise

15 Days (14 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Visits: Italy, Malta, Sicily, Tunisia, Sardinia, Spain, Portugal
Exclusive Savings
Oceanview
$7,203
Balcony
$8,869
Suite
$17,836
From (Per Person)
A$7,203
Save 147
Per Person
View Trip
15 Day Western Mediterranean & Iberia: Italy, France & Spain with Holland America
Cruise

15 Days (14 Nights) Rome to Lisbon
Operator: Holland America
Ship: Zuiderdam
Departure: 02 April 2028
Visits: Italy, France, Gibraltar, Spain, Morocco, Portugal
Fare Saver
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,092
Suite
-
From (Per Person)
A$5,092
Per Person
View Trip
17 Day Riviera Yacht Harbors Of France & Spain with Seabourn
Cruise

17 Days (16 Nights) Rome to Lisbon
Operator: Seabourn
Ship: Seabourn Ovation
Departure: 11 November 2028
Visits: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$16,398
Suite
$29,138
From (Per Person)
A$16,398
Save 300
Per Person
View Trip
14 Day Italia To Iberian Treasures with Oceania Cruises
Cruise

14 Days (13 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sonata
Departure: 19 October 2028
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, Portugal
Your World Inclusions
Exclusive Savings
Balcony
$8,951
Suite
$12,938
From (Per Person)
A$8,951
Save 2,259
Per Person
View Trip
8 Day Bolero Breeze with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 13 November 2028
Visits: Italy, Spain, Portugal
Exclusive Savings
Balcony
$7,902
Suite
$8,784
From (Per Person)
A$7,902
Save 6,628
Per Person
View Trip
11 Day Culinary Wonders with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 August 2027
Visits: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$10,883
Suite
$12,241
From (Per Person)
A$10,883
Save 8,117
Per Person
View Trip
18 Day Eternal Cities with Regent Seven Seas
Cruise

18 Days (17 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Explorer
Departure: 11 July 2028
Visits: Italy, Monaco, France, Spain, Gibraltar, Portugal
Exclusive Savings
Balcony
-
Suite
$40,696
From (Per Person)
A$40,696
Save 2,774
Per Person
View Trip
15 Day Spain, Portugal & the Mediterranean with Viking Cruises
Cruise

15 Days (14 Nights) Rome to Lisbon
Operator: Viking
Ships: Viking Astrea, Viking Jupiter +10 more, Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela
Departures: Feb 2027 to Aug 2029
Visits: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Balcony
$10,775
Suite
$15,479
From (Per Person)
A$10,775
Save 366
Per Person
View Trip
10 Day Caesars & Conquistadors with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Vista
Departure: 15 June 2027
Visits: Italy, Monaco, Spain, Gibraltar, Portugal
Your World Inclusions
Exclusive Savings
Balcony
$6,073
Suite
$9,361
From (Per Person)
A$6,073
Save 2,147
Per Person
View Trip
18 Day Civitavecchia to Lisbon with Crystal Cruises
New ReleaseCruise

18 Days (17 Nights) Rome to Lisbon
Operator: Crystal
Ship: Crystal Symphony
Departure: 01 October 2027
Visits: Italy, Sicily, Malta, Tunisia +4 more, Monaco, Corsica, Spain, Portugal
Exclusive Savings
Oceanview
$11,591
Balcony
$15,715
Suite
$16,154
From (Per Person)
A$11,591
Save 3,909
Per Person
View Trip
11 Day Renaissance To Algarve Sun with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Lisbon
Operator: Oceania
Ship: Oceania Sonata
Departure: 08 April 2028
Visits: Italy, France, Spain, Gibraltar, Portugal
Your World Inclusions
Exclusive Savings
Balcony
$7,727
Suite
$10,433
From (Per Person)
A$7,727
Save 2,223
Per Person
View Trip
12 Day Treasures of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Lisbon
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Visits: Italy, Sicily, Malta, Tunisia, Algeria, Spain, Portugal
Exclusive Savings
Balcony
$21,417
Suite
$27,484
From (Per Person)
A$21,417
Save 4,393
Per Person
View Trip
8 Day Spellbinding Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Lisbon
Operator: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 31 October 2027
Visits: Italy, France, Spain, Gibraltar, Portugal
Exclusive Savings
Balcony
$9,573
Suite
$11,533
From (Per Person)
A$9,573
Save 2,167
Per Person
View Trip
11 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise

11 Days (10 Nights) Rome to Lisbon
Operator: Silversea
Ship: Silver Spirit
Departure: 22 November 2027
Visits: Italy, Spain, Morocco, Portugal
Exclusive Savings
Oceanview
$10,192
Balcony
$12,152
Suite
$10,878
From (Per Person)
A$10,192
Save 208
Per Person
View Trip
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