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Cruises from Rome to Lisbon

Are you looking for a cruise from Rome to Lisbon? November is the most popular month to cruise between Rome and Lisbon and there are 44 departures available from eleven of the world's leading cruise lines.
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22 Days
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25 Cruises (44 Cruise Departures)
11 Day Culinary Wonders with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 August 2027
Visit: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,399
Suite
$12,599
From
US$11,399
Save 11,399
Per Person
View Trip
18 Day Italy, Spain & Portugal Cruise: Florence, Nice & Seville with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 30 October 2027
Visit: Italy, Monaco, France, Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$11,189
Oceanview
$12,289
Balcony
$14,449
Suite
$15,649
From
US$11,189
Per Person
View Trip
15 Day Rome to Lisbon with Silversea
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Visit: Italy, Malta, Sicily, Tunisia, Sardinia, Spain, Portugal
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$8,600
Balcony
$9,300
Suite
$16,800
From
US$9,300
Save 1,500
Per Person
View Trip
15 Day Spain, Portugal & the Mediterranean with Viking Cruises
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Libra (+8 more), Viking Lyra, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela
Departures: Jan 2027 to Sep 2028
Visit: Italy, Monaco, France, Spain, Morocco, Portugal
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$5,998
Suite
$9,398
From
US$5,998
Save 400
Per Person
View Trip
13 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Nova
Departure: 21 November 2027
Visit: Italy, France, Spain, Morocco, Portugal
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,200
Suite
$10,900
From
US$7,200
Save 3,500
Per Person
View Trip
10 Day Western Mediterranean Cruise From Rome To Lisbon with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 October 2027
Visit: Italy, France, Spain, Portugal
Inside
$2,219
Oceanview
$2,769
Balcony
$3,429
Suite
$4,229
From
US$2,219
Per Person
View Trip
12 Day Treasures of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Visit: Italy, Sicily, Malta, Tunisia, Algeria, Spain, Portugal
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,136
Suite
$21,581
From
US$16,136
Save 1,624
Per Person
View Trip
22 Day A Journey Across The Mediterranean’s Edge & Into The Atlantic with Explora Journeys
Cruise
 (1)

22 Days (21 Nights) Rome to Lisbon
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 February 2027
Visit: Italy, Sicily, Tunisia, Algeria, Spain, Morocco, Portugal
Inside
-
Oceanview
-
Balcony
-
Suite
$10,745
From
US$10,745
Per Person
View Trip
21 Day Summer Splendor with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 June 2027
Visit: Italy, Sicily, Sardinia, Corsica (+5 more), France, Spain, Gibraltar, Morocco, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$6,049
Oceanview
$6,599
Balcony
$10,699
Suite
$14,449
From
US$6,049
Save 6,049
Per Person
View Trip
11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2027
Visit: Italy, France, Spain, Portugal
Your World Inclusions
Exclusive Savings
Inside
$1,755
Oceanview
$1,950
Balcony
$3,150
Suite
$4,340
From
US$1,755
Save 3,643
Per Person
View Trip
10 Day Spain's Southern Coast & Riviera Gems with Seabourn
Cruise
 (1)

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 01 November 2026
Visit: Italy, Corsica, Sardinia, Spain, Portugal
Yours to Explore
Inside
-
Oceanview
$7,399
Balcony
$9,499
Suite
$15,584
From
US$7,399
Per Person
View Trip
15 Day Rivieras, Minarets & More with Oceania Cruises
Cruise
 (3)

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 28 April 2026
Visit: Italy, France, Spain, Morocco, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$15,999
From
US$15,999
Save 15,999
Per Person
View Trip
16 Day Italy, France & Spain Cruise: Rome, Barcelona & Seville with Azamara Cruises
Cruise
 (3)

16 Days (15 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 December 2027
Visit: Italy, France, Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$3,629
Oceanview
$4,549
Balcony
$5,739
Suite
$8,609
From
US$3,629
Per Person
View Trip
12 Day Mediterranean Rivieras with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 27 October 2026
Visit: Italy, Corsica, Spain, Morocco, Portugal
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,711
From
US$11,711
Save 1,179
Per Person
View Trip
18 Day Mediterranean & Iberian New Year Cruise: Italy, Spain & Morocco with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Visit: Italy, Spain, Morocco, Portugal
Azamara Always Included
Inside
-
Oceanview
$6,459
Balcony
-
Suite
$12,699
From
US$6,459
Per Person
View Trip
8 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise

8 Days (7 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 08 May 2026
Visit: Italy, Spain, Portugal
Last Minute Fare
Inside
-
Oceanview
$3,850
Balcony
$4,650
Suite
-
From
US$3,850
Per Person
View Trip
11 Day Western Mediterranean: Idyllic Isles & Hidden Gems with Holland America
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 24 May 2026
Visit: Italy, Sicily, Sardinia, Spain, Gibraltar, Portugal
Have It All Fare Option
Inside
$2,099
Oceanview
$2,199
Balcony
$2,949
Suite
$4,149
From
US$2,099
Per Person
View Trip
17 Day Rome to Lisbon with Silversea
Cruise
 (1)

17 Days (16 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visit: Italy, Sicily, Tunisia, Sardinia (+4 more), Spain, Gibraltar, Morocco, Portugal
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$8,400
Suite
$14,300
From
US$8,400
Per Person
View Trip
20 Day Mediterranean Isles Legacy with Oceania Cruises
Cruise
 (1)

20 Days (19 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 December 2026
Visit: Italy, Corsica, France, Spain, Gibraltar, Morocco, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$5,199
Oceanview
$5,499
Balcony
$8,549
Suite
$11,799
From
US$5,199
Save 5,199
Per Person
View Trip
15 Day Italy, French Riviera & Spain Collectors' Voyage with Holland America
Cruise
 (3)

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 26 July 2026
Visit: Italy, France, Gibraltar, Spain, Morocco, Portugal
Fare Saver
Inside
$1,904
Oceanview
$2,094
Balcony
$2,654
Suite
-
From
US$1,904
Per Person
View Trip
11 Day Roman Holiday with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 27 November 2027
Visit: Italy, Corsica, France, Spain, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,799
Oceanview
$3,649
Balcony
$4,399
Suite
$6,399
From
US$2,799
Save 2,799
Per Person
View Trip
11 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 22 November 2027
Visit: Italy, Spain, Morocco, Portugal
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$5,300
Balcony
$6,000
Suite
$5,500
From
US$6,000
Save 1,500
Per Person
View Trip
17 Day Riviera Yacht Harbors Of France & Spain with Seabourn
Cruise

17 Days (16 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 November 2028
Visit: Italy, Monaco, France, Spain, Morocco, Portugal
Inside
-
Oceanview
-
Balcony
$8,909
Suite
$14,579
From
US$8,909
Per Person
View Trip
11 Day Tuscan Summer with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 July 2026
Visit: Italy, France, Spain, Gibraltar, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,099
Suite
$13,999
From
US$13,099
Save 13,099
Per Person
View Trip
10 Day Caesars & Conquistadors with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 15 June 2027
Visit: Italy, Monaco, Spain, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,399
Suite
$6,849
From
US$4,399
Save 4,399
Per Person
View Trip
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