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Cruises from Rome to Lisbon

Are you looking for a cruise from Rome to Lisbon? November is the most popular month to cruise between Rome and Lisbon and there are 42 departures available from ten of the world's leading cruise lines.
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21 Cruises (42 Cruise Departures)
11 Day Western Mediterranean From Rome To Lisbon with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 18 November 2025
Countries Visited: Italy, France, Spain, Portugal
Inside
$1,548
Oceanview
$1,700
Balcony
$1,849
Suite
$2,751
From
1,548
per person
View Trip
12 Day Mediterranean Rivieras with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 27 October 2026
Countries Visited: Italy, Corsica, Spain, Morocco, Portugal
Exclusive DealFly Free Economy
Inside
-
Oceanview
$8,663
Balcony
-
Suite
$11,876
Save
8,927
From
8,663
per person
View Trip
18 Day Italy, Spain & Portugal Cruise: Florence, Nice & Seville with Azamara Cruises
Cruise
 (3)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 30 October 2027
Countries Visited: Italy, Monaco, France, Spain, Gibraltar, Portugal
Inside
$4,969
Oceanview
$5,709
Balcony
$7,149
Suite
$10,669
From
4,969
per person
View Trip
15 Day Spain, Portugal & the Mediterranean with Viking Cruises
Cruise
 (1)

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Libra (+7 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela
Departures: Nov 2026 to Sep 2028
Countries Visited: Italy, Monaco, France, Spain, Morocco, Portugal
Mutiple Deals Available
Inside
-
Oceanview
-
Balcony
$5,948
Suite
$8,498
From
5,948
per person
View Trip
10 Day Caesars & Conquistadors with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 15 June 2027
Countries Visited: Italy, Monaco, Spain, Gibraltar, Portugal
Exclusive Deal
Inside
-
Oceanview
-
Balcony
$4,299
Suite
$6,599
Save
4,299
From
4,299
per person
View Trip
21 Day Empires & Explorers with Oceania Cruises
Cruise
 (3)

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 18 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+5 more), Monaco, France, Spain, Portugal, Morocco
Exclusive Deal
Inside
-
Oceanview
-
Balcony
$8,999
Suite
-
Save
8,999
From
8,999
per person
View Trip
11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2027
Countries Visited: Italy, France, Spain, Portugal
Summer Of ChoiceExclusive Deal
Inside
$2,699
Oceanview
$2,999
Balcony
$4,499
Suite
$6,199
Save
2,699
From
2,699
per person
View Trip
11 Day Culinary Wonders with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 August 2027
Countries Visited: Italy, Monaco, France, Spain, Morocco, Portugal
Early Booking Saving
Inside
-
Oceanview
-
Balcony
$8,799
Suite
$9,949
Save
14,799
From
8,799
per person
View Trip
20 Day Mediterranean Isles Legacy with Oceania Cruises
Cruise
 (3)

20 Days (19 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 December 2026
Countries Visited: Italy, Corsica, France, Spain, Gibraltar, Morocco, Portugal
Exclusive Deal
Inside
$4,999
Oceanview
$5,499
Balcony
$8,199
Suite
$11,499
Save
4,999
From
4,999
per person
View Trip
11 Day Western Mediterranean: Idyllic Isles & Hidden Gems with Holland America
Cruise
 (2)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 24 May 2026
Countries Visited: Italy, Sicily, Sardinia, Spain, Gibraltar, Portugal
Exclusive Deal
Inside
$1,614
Oceanview
$1,764
Balcony
$2,464
Suite
$3,614
From
1,614
per person
View Trip
15 Day Rome to Lisbon with Silversea
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Countries Visited: Italy, Malta, Sicily, Tunisia, Sardinia, Spain, Portugal
Port-to-PortDoor-to-Door Upgrade Option
Inside
-
Oceanview
$7,600
Balcony
$8,200
Suite
$14,300
Save
2,500
From
7,600
per person
View Trip
13 Day Western Mediterranean From Rome To Lisbon with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 01 November 2025
Countries Visited: Italy, Sicily, Spain, Morocco, Portugal
Inside
$948
Oceanview
-
Balcony
$1,531
Suite
$1,651
From
948
per person
View Trip
13 Day Rome to Lisbon with Silversea
Cruise

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 November 2025
Countries Visited: Italy, Monaco, France, Spain, Portugal
Port-to-PortDoor-to-Door Upgrade Option
Inside
-
Oceanview
-
Balcony
-
Suite
$7,300
Save
2,500
From
7,300
per person
View Trip
18 Day Mediterranean & Iberian New Year Cruise: Italy, Spain & Morocco with Azamara Cruises
Cruise
 (3)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Countries Visited: Italy, Spain, Morocco, Portugal
Inside
$4,029
Oceanview
$4,729
Balcony
$5,579
Suite
$9,009
From
4,029
per person
View Trip
17 Day Rome to Lisbon with Silversea
Cruise

17 Days (16 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Countries Visited: Italy, Sicily, Tunisia, Sardinia (+4 more), Spain, Gibraltar, Morocco, Portugal
Port-to-PortDoor-to-Door Upgrade Option
Inside
-
Oceanview
-
Balcony
-
Suite
$9,200
From
9,200
per person
View Trip
15 Day Rivieras, Minarets & More with Oceania Cruises
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 28 April 2026
Countries Visited: Italy, France, Spain, Morocco, Portugal
Exclusive DealSummer Of Choice
Inside
$4,999
Oceanview
$6,049
Balcony
$5,747
Suite
$7,932
Save
4,999
From
4,999
per person
View Trip
11 Day Tuscan Summer with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 July 2026
Countries Visited: Italy, France, Spain, Gibraltar, Portugal
Early Booking Saving
Inside
-
Oceanview
-
Balcony
$9,399
Suite
$11,199
Save
14,799
From
9,399
per person
View Trip
21 Day Rome to Lisbon with Silversea
Cruise

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Muse
Departure: 31 July 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+5 more), Sardinia, Spain, Gibraltar, Morocco, Portugal
Port-to-PortDoor-to-Door Upgrade Option
Inside
-
Oceanview
$12,000
Balcony
$13,400
Suite
$17,600
From
12,000
per person
View Trip
12 Day Treasures of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Countries Visited: Italy, Sicily, Malta, Tunisia, Algeria, Spain, Portugal
Fly Free Premium EconomyFly Free Business Class
Inside
-
Oceanview
-
Balcony
$14,750
Suite
$23,150
Save
14,840
From
14,750
per person
View Trip
10 Day Spain's Southern Coast & Riviera Gems with Seabourn
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ships: Seabourn Encore, Seabourn Quest
Departures: Nov 2025 to Nov 2026
Countries Visited: Italy, Corsica, Sardinia, Spain, Portugal
Sail Into Savings
Inside
-
Oceanview
$5,698
Balcony
$4,798
Suite
$8,298
From
4,798
per person
View Trip
10 Day Western Mediterranean From Rome To Lisbon with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Sky
Departure: 14 October 2025
Countries Visited: Italy, France, Spain, Portugal
Inside
$949
Oceanview
$1,049
Balcony
$2,249
Suite
$4,549
From
949
per person
View Trip
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