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Mediterranean Short Break Cruises

Explore the best short cruise breaks sailing in and around the Mediterranean. Choose from 41 unique cruise itineraries from 3 leading cruise lines. October is the most popular month to join a short cruise break sailing in and around the Mediterranean with 62 departures starting between February 2026 and November 2027.
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41 Cruises (62 Cruise Departures)
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rome to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 20 April 2026
Visit: Italy, France, Spain
Inside
$299
Oceanview
$359
Balcony
$439
Suite
$859
From
US$299
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Kusadasi to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Oct 2026 to Oct 2027
Visit: Turkey, Italy
Inside
$403
Oceanview
-
Balcony
$523
Suite
-
From
US$403
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Valencia to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 10 September 2026
Visit: Spain, Sardinia, Italy
Inside
$369
Oceanview
$449
Balcony
$549
Suite
$1,069
From
US$369
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Seaview
Departures: Apr 2026 to Oct 2026
Visit: Italy, Spain, France
Bonus Onboard Credit
Inside
$575
Oceanview
$665
Balcony
$735
Suite
$1,275
From
US$575
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2026 to Oct 2026
Visit: Spain, Italy, France
Bonus Onboard Credit
Inside
$473
Oceanview
$523
Balcony
$705
Suite
$1,235
From
US$473
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 07 February 2026
Visit: Spain, France, Italy, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$869
From
US$869
Per Person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France
Inside
$79
Oceanview
$119
Balcony
$199
Suite
$339
From
US$79
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 13 November 2026
Visit: France, Italy, Corsica
Bonus Onboard Credit
Inside
$596
Oceanview
$656
Balcony
$746
Suite
$1,016
From
US$596
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (3)

4 Days (3 Nights) Genoa to Valletta
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 19 April 2026
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
-
Suite
$1,579
From
US$1,579
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Izmir to Bari
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 24 March 2026
Visit: Turkey, Greece, Italy
Inside
-
Oceanview
$409
Balcony
$689
Suite
$849
From
US$409
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Bari to Istanbul
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Oct 2026 to Mar 2027
Visit: Italy, Greece, Turkey
Inside
$329
Oceanview
$409
Balcony
$549
Suite
-
From
US$329
Per Person
View Trip
3 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Poesia
Departures: Apr 2026 to Apr 2026
Visit: Italy, France
Inside
$149
Oceanview
$189
Balcony
$256
Suite
-
From
US$149
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2026
Visit: Italy, Spain
Inside
$369
Oceanview
-
Balcony
$529
Suite
$1,259
From
US$369
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2026 to Oct 2026
Visit: Italy, France, Spain
Bonus Onboard Credit
Inside
$425
Oceanview
$505
Balcony
$585
Suite
$1,055
From
US$425
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Genoa to Malaga
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$509
Suite
$779
From
US$509
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (2)

2 Days (1 Nights) Barcelona to Marseille
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Feb 2026 to Apr 2026
Visit: Spain, France
Inside
$79
Oceanview
$129
Balcony
$169
Suite
$339
From
US$79
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France
Inside
$234
Oceanview
$281
Balcony
$460
Suite
$628
From
US$234
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Rome to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 27 October 2026
Visit: Italy, Sicily, Greece, Montenegro
Inside
$379
Oceanview
$489
Balcony
$599
Suite
$1,119
From
US$379
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (2)

3 Days (2 Nights) Bari to Athens
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Oct 2026 to Mar 2027
Visit: Italy, Greece
Inside
$179
Oceanview
$229
Balcony
$319
Suite
-
From
US$179
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (2)

3 Days (2 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Feb 2026 to Apr 2026
Visit: Spain, France, Italy
Inside
$253
Oceanview
-
Balcony
$249
Suite
$711
From
US$249
Per Person
View Trip
5 Day Mediterranean Getaway with Viking Cruises
New ReleaseCruise
 (2)

5 Days (4 Nights) Barcelona to Athens
Cruise Line: Viking Cruises
Ship: Viking Saturn
Departure: 01 February 2026
Visit: Spain, Malta, Greece
Viking $599 Air Deal
Inside
-
Oceanview
-
Balcony
$1,999
Suite
$2,599
From
US$1,999
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Valencia to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 25 April 2026
Visit: Spain, Italy
Inside
-
Oceanview
-
Balcony
$473
Suite
$923
From
US$473
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Seaview
Departures: Apr 2026 to Oct 2026
Visit: France, Italy, Spain
Bonus Onboard Credit
Inside
$556
Oceanview
$646
Balcony
$706
Suite
$1,256
From
US$556
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 05 May 2026
Visit: Spain, Tunisia, Sicily, Italy
Inside
$419
Oceanview
$529
Balcony
$629
Suite
$1,269
From
US$419
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Apr 2027
Visit: Spain, France, Italy
Bonus Onboard Credit
Inside
$563
Oceanview
$653
Balcony
$713
Suite
$1,183
From
US$563
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Feb 2026 to Oct 2026
Visit: Spain, France, Italy
Inside
$421
Oceanview
-
Balcony
$439
Suite
$1,011
From
US$421
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Amalfi to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 21 April 2026
Visit: Italy, Sicily, Tunisia, Spain
Inside
-
Oceanview
$625
Balcony
$675
Suite
$985
From
US$625
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain
Inside
-
Oceanview
$421
Balcony
$648
Suite
$872
From
US$421
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Mar 2026 to Apr 2027
Visit: Turkey, Greece, Italy
Inside
$269
Oceanview
$339
Balcony
$449
Suite
$609
From
US$269
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Florence to Valletta
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 27 April 2026
Visit: Italy, Sardinia, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$590
Suite
$820
From
US$590
Per Person
View Trip
Results: 1-30 of 41

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