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Mediterranean Short Break Cruises

Explore the best short cruise breaks sailing in and around the Mediterranean. Choose from 53 unique cruise itineraries with 44 past traveler reviews from 6 leading cruise lines. October is the most popular month to join a short cruise break sailing in and around the Mediterranean with 83 departures starting between May 2026 and June 2028.
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53 Cruises (83 Cruise Departures)
6 Day Grand Prix Weekend Cruise: Barcelona, Saint Tropez & Nice with Azamara Cruises
Cruise
 (8)

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 03 June 2027
Visit: Spain, France
Azamara Always Included
Inside
$2,109
Oceanview
$2,289
Balcony
$2,769
Suite
$3,979
From
US$2,109
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Bari to Istanbul
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Oct 2026 to Oct 2027
Visit: Italy, Greece, Turkey
Inside
$339
Oceanview
$419
Balcony
$569
Suite
$919
From
US$339
Per Person
View Trip
6 Day Springtime Along the Mediterranean with Ponant
Cruise
 (2)

6 Days (5 Nights) Nice to Rome
Cruise Line: Ponant
Ship: Le Boreal
Departure: 07 May 2027
Visit: France, Monaco, Italy, Corsica
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Athens to Bari
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Jan 2027 to May 2028
Visit: Greece, Turkey, Italy
Inside
$419
Oceanview
$489
Balcony
$749
Suite
$1,049
From
US$419
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Marseille to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 09 September 2026
Visit: France, Spain, Sardinia, Italy
Inside
-
Oceanview
-
Balcony
$799
Suite
$1,339
From
US$799
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Genoa to Valencia
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 21 October 2026
Visit: Italy, France, Spain
Inside
$329
Oceanview
$389
Balcony
$519
Suite
-
From
US$329
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 21 October 2026
Visit: France, Italy, Spain
Inside
$658
Oceanview
$790
Balcony
$825
Suite
$1,375
From
US$658
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 20 October 2027
Visit: France, Italy, Spain
Inside
$553
Oceanview
$683
Balcony
$743
Suite
$1,203
From
US$553
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Rome to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 27 October 2026
Visit: Italy, Sicily, Greece, Montenegro
Inside
$379
Oceanview
$489
Balcony
$599
Suite
$1,119
From
US$379
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 22 October 2026
Visit: Italy, Spain, France
Inside
$528
Oceanview
$596
Balcony
-
Suite
$1,230
From
US$528
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Apr 2028
Visit: Spain, France, Italy
Inside
$503
Oceanview
$583
Balcony
$653
Suite
$1,113
From
US$503
Per Person
View Trip
6 Day From Riviera Glamour to Corsican Charm with Ponant
Cruise
 (2)

6 Days (5 Nights) Barcelona to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 02 May 2027
Visit: Spain, France, Corsica
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,730
From
US$3,940
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Jan 2027 to May 2028
Visit: Turkey, Greece, Italy
Inside
$238
Oceanview
$308
Balcony
$428
Suite
$669
From
US$238
Per Person
View Trip
5 Day Break Between Provence and Catalonia with Ponant
Cruise
 (1)

5 Days (4 Nights) Nice to Barcelona
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 08 August 2027
Visit: France, Spain
Inside
-
Oceanview
-
Balcony
$3,050
Suite
$5,650
From
US$3,050
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Kusadasi to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 26 October 2026
Visit: Turkey, Italy
Inside
-
Oceanview
-
Balcony
$593
Suite
$1,413
From
US$593
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Bari to Athens
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Oct 2026 to Mar 2027
Visit: Italy, Greece
Inside
$164
Oceanview
$224
Balcony
$319
Suite
$454
From
US$164
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 30 October 2026
Visit: Italy, Spain
Inside
$340
Oceanview
$450
Balcony
$488
Suite
$804
From
US$340
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Venice to Rome
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 14 November 2027
Visit: Italy, Greece
Inside
$369
Oceanview
$449
Balcony
$729
Suite
$889
From
US$369
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (3)

5 Days (4 Nights) Valletta to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 04 November 2026
Visit: Malta, Spain, France, Italy
Inside
-
Oceanview
-
Balcony
$569
Suite
$1,069
From
US$569
Per Person
View Trip
6 Day Andalusia and Moroccan Shores with Ponant
Cruise
 (1)

6 Days (5 Nights) Malaga to Malaga
Cruise Line: Ponant
Ship: Le Bougainville
Departures: Nov 2026 to Nov 2026
Visit: Spain, Gibraltar, Morocco
Inside
-
Oceanview
-
Balcony
$3,760
Suite
$6,950
From
US$3,760
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Valencia to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 10 September 2026
Visit: Spain, Sardinia, Italy
Inside
-
Oceanview
-
Balcony
$639
Suite
-
From
US$639
Per Person
View Trip
6 Day Grand Prix Weekend Cruise: Barcelona, Cannes & Nice with Azamara Cruises
Cruise
 (3)

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 01 June 2028
Visit: Spain, France
Azamara Always Included
Inside
$1,559
Oceanview
$1,709
Balcony
$2,099
Suite
$4,859
From
US$1,559
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 21 October 2027
Visit: Italy, Spain, France
Inside
$570
Oceanview
$700
Balcony
$780
Suite
$1,220
From
US$570
Per Person
View Trip
6 Day An Autumn Escape: Côte d’Azur, Italian Riviera & Corsica with Ponant
Cruise
 (2)

6 Days (5 Nights) Nice to Florence
Cruise Line: Ponant
Ship: Le Boreal
Departure: 28 September 2027
Visit: France, Italy, Corsica
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Musica
Departures: Oct 2026 to Nov 2027
Visit: France, Italy
Inside
$261
Oceanview
$296
Balcony
$326
Suite
$546
From
US$261
Per Person
View Trip
6 Day Sicilian interlude with Ponant
Cruise
 (2)

6 Days (5 Nights) Palermo to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 June 2027
Visit: Sicily, Italy, Malta
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 19 October 2027
Visit: Spain, France, Italy
Inside
$553
Oceanview
$683
Balcony
$743
Suite
$1,203
From
US$553
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 29 October 2026
Visit: Italy, Spain
Inside
$290
Oceanview
$355
Balcony
$535
Suite
$634
From
US$290
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 27 October 2026
Visit: Spain, Italy, France
Inside
-
Oceanview
$506
Balcony
$776
Suite
$1,526
From
US$506
Per Person
View Trip
5 Day Northern Europe with MSC Cruises
Cruise

5 Days (4 Nights) Malaga to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 12 November 2026
Visit: Spain, France
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$3,299
From
US$3,299
Per Person
View Trip
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