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Mediterranean Short Break Cruises

Explore the best short cruise breaks sailing in and around the Mediterranean. Choose from 83 unique cruise itineraries with 67 past traveler reviews from 8 leading cruise lines. April and October are the most popular months to join a short cruise break sailing in and around the Mediterranean with 116 departures starting between April 2026 and May 2028.
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83 Cruises (116 Cruise Departures)
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Apr 2028
Visit: Spain, France, Italy
Inside
$527
Oceanview
$653
Balcony
$718
Suite
$1,165
From
US$527
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 24 October 2026
Visit: Spain, France, Italy
Inside
$329
Oceanview
$379
Balcony
$439
Suite
$1,329
From
US$329
Per Person
View Trip
6 Day Sicilian interlude with Ponant
Cruise
 (2)

6 Days (5 Nights) Palermo to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 June 2027
Visit: Sicily, Italy, Malta
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Barcelona to Florence
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 10 May 2026
Visit: Spain, France, Italy
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$859
From
US$859
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (3)

6 Days (5 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC World Europa
Departures: Apr 2026 to Nov 2026
Visit: Italy, Sicily, Malta, Spain
Inside
$439
Oceanview
$599
Balcony
$729
Suite
$1,229
From
US$439
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Athens to Bari
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Jan 2027 to May 2028
Visit: Greece, Turkey, Italy
Inside
$409
Oceanview
$489
Balcony
$749
Suite
$1,049
From
US$409
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$765
Suite
-
From
US$765
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 16 April 2026
Visit: Spain, France, Italy
Inside
-
Oceanview
-
Balcony
$541
Suite
$1,721
From
US$541
Per Person
View Trip
6 Day An Autumn Escape: Côte d’Azur, Italian Riviera & Corsica with Ponant
Cruise
 (2)

6 Days (5 Nights) Nice to Florence
Cruise Line: Ponant
Ship: Le Boreal
Departure: 28 September 2027
Visit: France, Italy, Corsica
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 19 April 2026
Visit: Italy, Spain, France
Inside
-
Oceanview
-
Balcony
$758
Suite
-
From
US$758
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2026 to Oct 2026
Visit: France, Spain, Italy
Inside
$573
Oceanview
$616
Balcony
$696
Suite
$1,126
From
US$573
Per Person
View Trip
6 Day Corsica and the French Riviera with Ponant
Cruise
 (1)

6 Days (5 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 20 May 2026
Visit: France, Monaco, Corsica
Inside
-
Oceanview
-
Balcony
$4,240
Suite
$7,890
From
US$4,240
Per Person
View Trip
6 Day Corsica and the French Riviera with Ponant
Cruise
 (1)

6 Days (5 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 20 May 2026
Visit: France, Corsica
Inside
-
Oceanview
-
Balcony
$4,710
Suite
$8,360
From
US$4,710
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 24 October 2026
Visit: Spain, France, Italy, Sicily
Inside
$413
Oceanview
-
Balcony
-
Suite
-
From
US$413
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 19 October 2027
Visit: Spain, France, Italy
Inside
$553
Oceanview
$683
Balcony
$743
Suite
$1,203
From
US$553
Per Person
View Trip
6 Day A Journey Of Sculpted Isles & Timeless Civilisations with Explora Journeys
Cruise

6 Days (5 Nights) Athens to Valletta
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 April 2026
Visit: Greece, Sicily, Malta
Inside
-
Oceanview
-
Balcony
-
Suite
$3,150
From
US$3,150
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Bari to Istanbul
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Oct 2026 to Oct 2027
Visit: Italy, Greece, Turkey
Inside
$339
Oceanview
$419
Balcony
$569
Suite
$919
From
US$339
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Valencia to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 10 September 2026
Visit: Spain, Sardinia, Italy
Inside
-
Oceanview
-
Balcony
$639
Suite
-
From
US$639
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2026
Visit: Italy, Spain
Inside
$339
Oceanview
$429
Balcony
$519
Suite
$1,259
From
US$339
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Seaview
Departures: Apr 2026 to Oct 2026
Visit: France, Italy, Spain
Inside
$424
Oceanview
$544
Balcony
$614
Suite
$1,164
From
US$424
Per Person
View Trip
6 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Barcelona to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 18 April 2026
Visit: Spain, Italy, France
Inside
-
Oceanview
$553
Balcony
$803
Suite
$1,313
From
US$553
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 20 October 2027
Visit: France, Italy, Spain
Inside
$553
Oceanview
$683
Balcony
$743
Suite
$1,203
From
US$553
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Marseille to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 22 April 2026
Visit: France, Italy, Spain
Inside
$554
Oceanview
$634
Balcony
$704
Suite
$1,104
From
US$554
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Musica
Departures: Oct 2026 to Nov 2027
Visit: France, Italy
Inside
$256
Oceanview
$296
Balcony
$326
Suite
$546
From
US$256
Per Person
View Trip
6 Day Palma De Mallorca to Nice with Silversea
Cruise

6 Days (5 Nights) Palma de Mallorca to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: Jun 2026 to Aug 2026
Visit: Spain, France
Last Minute Fare
All-Inclusive Plus Fare
All-Inclusive Fare
Inside
-
Oceanview
$3,050
Balcony
$3,250
Suite
$9,900
From
US$3,050
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2026 to Oct 2026
Visit: Spain, Italy, France
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
$798
Suite
$1,533
From
US$798
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Marseille to Tunis
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 01 June 2026
Visit: France, Spain, Tunisia
Inside
-
Oceanview
-
Balcony
$579
Suite
-
From
US$579
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 04 December 2026
Visit: Spain, France, Italy
Inside
$467
Oceanview
$547
Balcony
$627
Suite
$1,057
From
US$467
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 17 April 2026
Visit: France, Italy, Spain
Inside
$849
Oceanview
$919
Balcony
$1,040
Suite
$1,440
From
US$849
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (2)

6 Days (5 Nights) Barcelona to Bari
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 27 April 2026
Visit: Spain, Malta, Greece, Italy
Inside
$365
Oceanview
$495
Balcony
$625
Suite
$1,075
From
US$365
Per Person
View Trip
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