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Mediterranean Short Break Cruises

Explore the best short cruise breaks sailing in and around the Mediterranean. Choose from 58 unique cruise itineraries with 41 past traveler reviews from 4 leading cruise lines. April is the most popular month to join a short cruise break sailing in and around the Mediterranean with 85 departures starting between March 2026 and May 2028.
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58 Cruises (85 Cruise Departures)
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Marseille to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 20 April 2026
Visit: France, Italy
Inside
-
Oceanview
-
Balcony
$509
Suite
-
From
US$509
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Rome to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 27 October 2026
Visit: Italy, Sicily, Greece, Montenegro
Inside
-
Oceanview
$539
Balcony
$689
Suite
$1,119
From
US$539
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Valencia to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 25 April 2026
Visit: Spain, Italy
Inside
-
Oceanview
-
Balcony
$563
Suite
$1,013
From
US$563
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Bari to Athens
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra
Departures: Oct 2026 to Mar 2027
Visit: Italy, Greece
Inside
$179
Oceanview
$229
Balcony
$319
Suite
$489
From
US$179
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Musica
Departures: Oct 2026 to Nov 2027
Visit: France, Italy
Inside
$256
Oceanview
$296
Balcony
$326
Suite
$546
From
US$256
Per Person
View Trip
5 Day A Journey Through Riviera Elegance & Coastal Splendour with Explora Journeys
Cruise
 (1)

5 Days (4 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 April 2026
Visit: Spain, Monaco, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$2,640
From
US$2,640
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Amalfi to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 17 October 2026
Visit: Italy, France, Spain
Inside
$449
Oceanview
$379
Balcony
$449
Suite
-
From
US$379
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 19 October 2027
Visit: Spain, France, Italy
Inside
$593
Oceanview
$683
Balcony
$743
Suite
$1,203
From
US$593
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Kusadasi to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 25 October 2027
Visit: Turkey, Italy
Inside
$403
Oceanview
-
Balcony
$583
Suite
-
From
US$403
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Lirica, MSC Orchestra
Departures: Jun 2026 to May 2028
Visit: Turkey, Greece, Italy
Inside
$249
Oceanview
$339
Balcony
$469
Suite
$669
From
US$249
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (3)

5 Days (4 Nights) Valletta to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 04 November 2026
Visit: Malta, Spain, France, Italy
Inside
-
Oceanview
-
Balcony
$579
Suite
-
From
US$579
Per Person
View Trip
3 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Poesia
Departures: Apr 2026 to Apr 2026
Visit: Italy, France
Inside
-
Oceanview
$189
Balcony
$256
Suite
-
From
US$189
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 04 December 2026
Visit: Spain, France, Italy
Inside
$467
Oceanview
$567
Balcony
$627
Suite
$1,654
From
US$467
Per Person
View Trip
5 Day Break Between Provence and Catalonia with Ponant
Cruise
 (1)

5 Days (4 Nights) Nice to Barcelona
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 08 August 2027
Visit: France, Spain
Inside
-
Oceanview
-
Balcony
$3,050
Suite
$5,650
From
US$3,050
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 14 November 2026
Visit: Italy, Corsica, France, Spain
Inside
-
Oceanview
-
Balcony
$895
Suite
$1,025
From
US$895
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 21 October 2027
Visit: Italy, Spain, France
Inside
$570
Oceanview
$700
Balcony
$780
Suite
$1,220
From
US$570
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 28 April 2026
Visit: Italy, Spain, France
Inside
$299
Oceanview
$389
Balcony
$489
Suite
$729
From
US$299
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2026
Visit: Italy, Spain
Inside
$339
Oceanview
$429
Balcony
$519
Suite
$1,259
From
US$339
Per Person
View Trip
4 Day Spain & France Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ship: Harmony of the Seas
Departure: 21 May 2026
Visit: Spain, France
Exclusive Savings
Inside
$466
Oceanview
$594
Balcony
$592
Suite
$972
From
US$466
Save 246
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (2)

3 Days (2 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 11 April 2026
Visit: Spain, France, Italy
Inside
$149
Oceanview
$209
Balcony
$279
Suite
$489
From
US$149
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 14 November 2026
Visit: Italy, Corsica, France
Inside
$279
Oceanview
$369
Balcony
$469
Suite
$779
From
US$279
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 24 October 2026
Visit: Spain, France, Italy
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$1,329
From
US$1,329
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Barcelona to Florence
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 10 May 2026
Visit: Spain, France, Italy
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$859
From
US$859
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Palermo to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 29 April 2026
Visit: Sicily, Malta, Spain
Inside
-
Oceanview
-
Balcony
$419
Suite
-
From
US$419
Per Person
View Trip
5 Day A Journey Through Legendary Crossroads & Island Spirit with Explora Journeys
Cruise

5 Days (4 Nights) Valletta to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 29 April 2026
Visit: Malta, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$2,510
From
US$2,510
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 06 April 2026
Visit: Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$498
Suite
-
From
US$498
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2026 to Oct 2026
Visit: France, Spain, Italy
Inside
$566
Oceanview
$626
Balcony
$696
Suite
$1,126
From
US$566
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Bari to Athens
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 04 April 2026
Visit: Italy, Greece
Inside
$341
Oceanview
$461
Balcony
$631
Suite
$751
From
US$341
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 30 October 2026
Visit: Italy, Spain
Inside
$379
Oceanview
$479
Balcony
$559
Suite
$849
From
US$379
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Apr 2028
Visit: Spain, France, Italy
Inside
$527
Oceanview
$653
Balcony
$718
Suite
$1,165
From
US$527
Per Person
View Trip
Results: 1-30 of 58

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