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Mediterranean Short Break Cruises

Explore the best short cruise breaks sailing in and around the Mediterranean. Choose from 42 unique cruise itineraries from 2 leading cruise lines. April and October are the most popular months to join a short cruise break sailing in and around the Mediterranean with 62 departures starting between December 2025 and November 2027.
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5 Days
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42 Cruises (62 Cruise Departures)
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 05 December 2026
Visit: France, Italy
Inside
-
Oceanview
$270
Balcony
$300
Suite
$720
From
US$270
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (2)

3 Days (2 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Feb 2026 to Apr 2026
Visit: Spain, France, Italy
Inside
$139
Oceanview
-
Balcony
$259
Suite
$529
From
US$139
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Valencia to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 25 April 2026
Visit: Spain, Italy
Inside
-
Oceanview
-
Balcony
$463
Suite
$923
From
US$463
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Kusadasi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Apr 2026 to Apr 2027
Visit: Italy, Greece, Turkey
Inside
$289
Oceanview
$339
Balcony
$409
Suite
$1,099
From
US$289
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 27 October 2026
Visit: Spain, Italy, France
Inside
$443
Oceanview
$503
Balcony
$563
Suite
$1,033
From
US$443
Per Person
View Trip
4 Day Spain & France Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ship: Harmony of the Seas
Departure: 21 May 2026
Visit: Spain, France
Bonus Onboard Credit
Exclusive Savings
Inside
$650
Oceanview
$701
Balcony
$738
Suite
$1,361
From
US$650
Save 236
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 13 November 2026
Visit: France, Italy, Corsica
Inside
$557
Oceanview
$656
Balcony
$743
Suite
$1,021
From
US$557
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France
Inside
$178
Oceanview
$228
Balcony
$388
Suite
$628
From
US$178
Per Person
View Trip
3 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ships: MSC Musica, MSC Poesia
Departures: Apr 2026 to Oct 2026
Visit: Italy, France
Inside
$169
Oceanview
$171
Balcony
$309
Suite
$579
From
US$169
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Palermo to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 07 January 2026
Visit: Sicily, Tunisia, Spain
Inside
$155
Oceanview
-
Balcony
$300
Suite
$600
From
US$155
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (2)

2 Days (1 Nights) Barcelona to Marseille
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Splendida
Departures: Feb 2026 to Apr 2026
Visit: Spain, France
Inside
$79
Oceanview
$129
Balcony
$169
Suite
$339
From
US$79
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Feb 2026 to Oct 2026
Visit: Spain, France, Italy
Inside
$279
Oceanview
$349
Balcony
$409
Suite
$859
From
US$279
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Seaview
Departures: Apr 2026 to Oct 2026
Visit: Italy, Spain, France
Inside
$540
Oceanview
$630
Balcony
$700
Suite
$1,230
From
US$540
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Feb 2026 to Oct 2026
Visit: Spain, France, Italy, Sicily
Inside
$279
Oceanview
$419
Balcony
$489
Suite
$869
From
US$279
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Florence to Valletta
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 27 April 2026
Visit: Italy, Sardinia, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$449
Suite
-
From
US$449
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Rome
Cruise Line: MSC Cruises
Ship: MSC World Asia
Departure: 11 December 2026
Visit: Spain, France, Italy
Inside
-
Oceanview
-
Balcony
$559
Suite
-
From
US$559
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 06 April 2026
Visit: Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$524
Suite
-
From
US$524
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Izmir to Bari
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 24 March 2026
Visit: Turkey, Greece, Italy
Inside
-
Oceanview
$409
Balcony
$689
Suite
$849
From
US$409
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2026 to Oct 2026
Visit: Spain, Italy, France
Inside
$456
Oceanview
$506
Balcony
$606
Suite
$1,151
From
US$456
Per Person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Opera
Departures: Dec 2025 to May 2026
Visit: Italy, France
Inside
$79
Oceanview
$119
Balcony
$199
Suite
$339
From
US$79
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2026
Visit: Italy, Spain
Inside
-
Oceanview
$469
Balcony
$529
Suite
$819
From
US$469
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Amalfi to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Jan 2026 to Apr 2026
Visit: Italy, Sicily, Tunisia, Spain
Inside
$203
Oceanview
$605
Balcony
$366
Suite
$676
From
US$203
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Apr 2027
Visit: Spain, France, Italy
Inside
$526
Oceanview
$616
Balcony
$676
Suite
$1,136
From
US$526
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (3)

4 Days (3 Nights) Genoa to Valletta
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 19 April 2026
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$599
Suite
$1,579
From
US$599
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rome to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 05 October 2026
Visit: Italy, France, Spain
Inside
$289
Oceanview
$359
Balcony
$479
Suite
$849
From
US$289
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Naples to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 09 November 2026
Visit: Italy, Sicily, Malta, Spain
Inside
-
Oceanview
$359
Balcony
-
Suite
-
From
US$359
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (3)

4 Days (3 Nights) Marseille to Valletta
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 20 February 2026
Visit: France, Italy, Malta
Inside
$282
Oceanview
$349
Balcony
$469
Suite
-
From
US$282
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Ship: MSC Lirica
Departure: 25 March 2026
Visit: Turkey, Greece, Italy
Inside
-
Oceanview
-
Balcony
$489
Suite
$609
From
US$489
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Seaview
Departures: Apr 2026 to Oct 2026
Visit: France, Italy, Spain
Inside
$523
Oceanview
$613
Balcony
$673
Suite
$1,188
From
US$523
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2027 to Oct 2027
Visit: France, Spain, Italy
Inside
$403
Oceanview
$523
Balcony
$583
Suite
$1,023
From
US$403
Per Person
View Trip
Results: 1-30 of 42

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