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Mediterranean Short Break Cruises

Explore the best short cruise breaks sailing in and around the Mediterranean. Choose from 39 unique cruise itineraries with 38 past traveler reviews from 3 leading cruise lines. April is the most popular month to join a short cruise break sailing in and around the Mediterranean with 58 departures starting between February 2026 and November 2027.
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2 Days
5 Days
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39 Cruises (58 Cruise Departures)
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 04 December 2026
Visit: Spain, France, Italy
Bonus Onboard Credit
Inside
-
Oceanview
$574
Balcony
$644
Suite
$1,074
From
US$574
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Marseille to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 20 April 2026
Visit: France, Italy
Inside
-
Oceanview
-
Balcony
$509
Suite
-
From
US$509
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rome to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 20 April 2026
Visit: Italy, France, Spain
Inside
$299
Oceanview
$349
Balcony
$439
Suite
$859
From
US$299
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Bari to Istanbul
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Oct 2026 to Mar 2027
Visit: Italy, Greece, Turkey
Inside
$329
Oceanview
$409
Balcony
$549
Suite
-
From
US$329
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France
Inside
$234
Oceanview
$281
Balcony
$460
Suite
$628
From
US$234
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2027 to Nov 2027
Visit: France, Spain, Italy
Bonus Onboard Credit
Inside
$443
Oceanview
$523
Balcony
$583
Suite
$1,023
From
US$443
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 13 November 2026
Visit: France, Italy, Corsica
Bonus Onboard Credit
Inside
$586
Oceanview
$666
Balcony
$746
Suite
$1,016
From
US$586
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 28 April 2026
Visit: Italy, Spain, France
Inside
$329
Oceanview
$409
Balcony
$489
Suite
$729
From
US$329
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Kusadasi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Apr 2026 to Apr 2027
Visit: Italy, Greece, Turkey
Inside
$299
Oceanview
$339
Balcony
$409
Suite
$1,099
From
US$299
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Apr 2027
Visit: Spain, France, Italy
Bonus Onboard Credit
Inside
$563
Oceanview
$653
Balcony
$713
Suite
$1,183
From
US$563
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (2)

3 Days (2 Nights) Bari to Athens
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Oct 2026 to Mar 2027
Visit: Italy, Greece
Inside
$179
Oceanview
$229
Balcony
$319
Suite
-
From
US$179
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (2)

3 Days (2 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 11 April 2026
Visit: Spain, France, Italy
Inside
$119
Oceanview
$179
Balcony
$249
Suite
$799
From
US$119
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 April 2026
Visit: Italy, Spain
Inside
-
Oceanview
-
Balcony
$529
Suite
$1,259
From
US$529
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Seaview
Departures: Apr 2026 to Oct 2026
Visit: France, Italy, Spain
Bonus Onboard Credit
Inside
$516
Oceanview
$646
Balcony
$706
Suite
$1,256
From
US$516
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (3)

5 Days (4 Nights) Valletta to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 04 November 2026
Visit: Malta, Spain, France, Italy
Inside
-
Oceanview
-
Balcony
$589
Suite
-
From
US$589
Per Person
View Trip
4 Day Spain & France Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ship: Harmony of the Seas
Departure: 21 May 2026
Visit: Spain, France
Inside
$401
Oceanview
-
Balcony
$450
Suite
$1,051
From
US$401
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (2)

2 Days (1 Nights) Barcelona to Marseille
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 11 April 2026
Visit: Spain, France
Inside
$132
Oceanview
$172
Balcony
$212
Suite
$352
From
US$132
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 28 April 2026
Visit: Italy, Spain
Inside
$229
Oceanview
$279
Balcony
$339
Suite
$689
From
US$229
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (3)

4 Days (3 Nights) Barcelona to Rome
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 27 February 2026
Visit: Spain, France, Italy
Inside
-
Oceanview
-
Balcony
$489
Suite
-
From
US$489
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Rome to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 27 October 2026
Visit: Italy, Sicily, Greece, Montenegro
Inside
$419
Oceanview
$489
Balcony
$599
Suite
$1,119
From
US$419
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Seaview
Departures: Apr 2026 to Oct 2026
Visit: Italy, Spain, France
Bonus Onboard Credit
Inside
$575
Oceanview
$665
Balcony
$735
Suite
$1,275
From
US$575
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Valencia to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 25 April 2026
Visit: Spain, Italy
Inside
-
Oceanview
-
Balcony
$473
Suite
-
From
US$473
Per Person
View Trip
5 Day Break Between Provence and Catalonia with Ponant
Cruise
 (1)

5 Days (4 Nights) Nice to Barcelona
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 08 August 2027
Visit: France, Spain
Inside
-
Oceanview
-
Balcony
$3,050
Suite
$5,650
From
US$3,050
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Istanbul to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Jan 2027 to Apr 2027
Visit: Turkey, Greece, Italy
Inside
$269
Oceanview
$339
Balcony
$449
Suite
$889
From
US$269
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Amalfi to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 21 April 2026
Visit: Italy, Sicily, Tunisia, Spain
Inside
$394
Oceanview
$498
Balcony
$568
Suite
$878
From
US$394
Per Person
View Trip
3 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 20 April 2026
Visit: Italy, France
Inside
-
Oceanview
-
Balcony
$259
Suite
-
From
US$259
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 06 April 2026
Visit: Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$536
Suite
-
From
US$536
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Valencia to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 10 September 2026
Visit: Spain, Sardinia, Italy
Inside
-
Oceanview
$449
Balcony
$619
Suite
$1,069
From
US$449
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (1)

3 Days (2 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC Musica
Departures: Oct 2026 to Nov 2027
Visit: France, Italy
Bonus Onboard Credit
Inside
$225
Oceanview
$265
Balcony
$295
Suite
$515
From
US$225
Per Person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France
Inside
$79
Oceanview
$119
Balcony
-
Suite
-
From
US$79
Per Person
View Trip
Results: 1-30 of 39

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