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Mediterranean Short Break Cruises

Explore the best short cruise breaks sailing in and around the Mediterranean. Choose from 83 unique cruise itineraries with 67 past traveler reviews from 10 leading cruise lines. April and October are the most popular months to join a short cruise break sailing in and around the Mediterranean with 116 departures starting between April 2026 and May 2028.
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6 Days
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83 Cruises (116 Cruise Departures)
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Marseille to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 20 April 2026
Visit: France, Italy
Inside
-
Oceanview
-
Balcony
$509
Suite
-
From
US$509
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Athens to Valencia
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 26 October 2026
Visit: Greece, Sicily, Spain
Inside
$419
Oceanview
$569
Balcony
$909
Suite
$1,109
From
US$419
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2026 to Oct 2026
Visit: Italy, France, Spain
Inside
$475
Oceanview
$525
Balcony
$585
Suite
$1,055
From
US$475
Per Person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Marseille to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 19 October 2026
Visit: France, Spain
Inside
$89
Oceanview
$149
Balcony
$199
Suite
$479
From
US$89
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Athens to Bari
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 16 June 2026
Visit: Greece, Italy
Inside
$407
Oceanview
-
Balcony
$807
Suite
$967
From
US$407
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 14 October 2027
Visit: Italy, France, Sardinia
Inside
$632
Oceanview
$712
Balcony
$980
Suite
$1,068
From
US$632
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Barcelona to Livorno
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 05 May 2026
Visit: Spain, Tunisia, Sicily, Italy
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$2,819
From
US$2,819
Per Person
View Trip
6 Day Nice to Malaga with Silversea
Cruise

6 Days (5 Nights) Nice to Malaga
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 30 August 2026
Visit: France, Spain
Last Minute Fare
Inside
-
Oceanview
$2,950
Balcony
$3,150
Suite
-
From
US$2,950
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Genoa to Malaga
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France, Spain
Inside
$239
Oceanview
-
Balcony
$599
Suite
$779
From
US$239
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2026 to Oct 2027
Visit: France, Spain, Italy
Inside
$597
Oceanview
$687
Balcony
$757
Suite
$1,307
From
US$597
Per Person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France
Inside
$79
Oceanview
$119
Balcony
$199
Suite
-
From
US$79
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France
Inside
-
Oceanview
-
Balcony
$460
Suite
$628
From
US$460
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 05 May 2026
Visit: Spain, Tunisia, Sicily, Italy
Inside
$419
Oceanview
-
Balcony
-
Suite
-
From
US$419
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2027 to Nov 2027
Visit: Italy, France, Spain
Inside
$460
Oceanview
$535
Balcony
$600
Suite
$1,040
From
US$460
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2027 to Nov 2027
Visit: France, Spain, Italy
Inside
$443
Oceanview
$523
Balcony
$583
Suite
$1,023
From
US$443
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 27 October 2026
Visit: Spain, Italy, France
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$1,526
From
US$1,526
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departures: Oct 2026 to Oct 2027
Visit: Italy, France, Spain
Inside
$558
Oceanview
$627
Balcony
$717
Suite
$1,268
From
US$558
Per Person
View Trip
6 Day Côte d'Azur & Beyond with Emerald Cruises
New ReleaseCruise

6 Days (5 Nights) Nice to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 21 May 2026
Visit: France, Italy, Monaco
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$13,081
From
US$13,081
Save 1,389
Per Person
View Trip
4 Day Spain & France Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ship: Harmony of the Seas
Departure: 21 May 2026
Visit: Spain, France
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$992
From
US$1,670
Per Person
View Trip
5 Day A Journey Through Legendary Crossroads & Island Spirit with Explora Journeys
Cruise

5 Days (4 Nights) Valletta to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 29 April 2026
Visit: Malta, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$2,510
From
US$2,510
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 20 April 2026
Visit: Italy, Sicily, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
$548
Suite
$1,725
From
US$548
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Palermo to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 16 October 2026
Visit: Sicily, Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$639
Suite
-
From
US$639
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Amalfi to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 17 October 2026
Visit: Italy, France, Spain
Inside
$449
Oceanview
$379
Balcony
$449
Suite
-
From
US$379
Per Person
View Trip
Results: 61-83 of 83

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