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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 679 unique cruise itineraries with 1209 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 773 departures starting between March 2026 and October 2028.
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679 Cruises (773 Cruise Departures)
9 Day Historical Cities of the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 01 June 2026
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$7,540
Suite
$14,120
From
US$7,540
Per Person
View Trip
8 Day French & Italian Rivieras with Corsica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Sakara
Departures: Apr 2026 to Aug 2027
Visit: France, Monaco, Italy, Corsica
Preferred Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
$7,294
Balcony
-
Suite
$9,161
From
US$7,294
Save 267
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: May 2026 to Jul 2026
Visit: France, Corsica, Sardinia, Spain
All-Inclusive Plus Fare
Last Minute Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$6,550
Balcony
$7,050
Suite
$17,500
From
US$6,550
Save 1,500
Per Person
View Trip
9 Day Peaceful Islands and Ancient Treasures of the Mediterranean with Ponant
Cruise
 (2)

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 17 August 2027
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$6,510
Suite
$12,100
From
US$6,510
Per Person
View Trip
8 Day Barcelona to Rome with Silversea
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 01 November 2026
Visit: Spain, Sardinia, Tunisia, Sicily, Italy
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,100
Suite
$9,900
From
US$5,100
Save 1,500
Per Person
View Trip
10 Day Greek & Italian Isles with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 06 October 2027
Visit: Italy, Sicily, Tunisia, Malta, Greece
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,195
Suite
$5,893
From
US$4,195
Save 4,403
Per Person
View Trip
12 Day Cultures of the Mediterranean Barcelona to Civitavecchia with Emerald Cruises
New ReleaseCruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: May 2027 to Sep 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Preferred Plus Fare + Air Credit
Select Fare
Exclusive Savings
Inside
-
Oceanview
$9,373
Balcony
-
Suite
$12,350
From
US$9,373
Save 1,179
Per Person
View Trip
12 Day Best Of The Mediterranean Cruise: Villefranche, Florence & Palamos with Azamara Cruises
Cruise
 (5)

12 Days (11 Nights) Nice to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 22 May 2026
Visit: France, Corsica, Italy, Spain
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$1,979
Oceanview
$2,159
Balcony
-
Suite
-
From
US$1,979
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Nice & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 December 2027
Visit: Italy, France, Spain
Azamara Always Included
Inside
$1,609
Oceanview
$2,029
Balcony
$2,569
Suite
$3,859
From
US$1,609
Per Person
View Trip
12 Day Idyllic Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 13 September 2028
Visit: Italy, Sardinia, Corsica, Spain
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,456
Suite
$18,940
From
US$16,456
Save 1,289
Per Person
View Trip
8 Day Balearic & Riviera Resorts with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 12 October 2026
Visit: Italy, Sardinia, Spain, France, Monaco
Your World Inclusions
Exclusive Savings
Inside
$1,680
Oceanview
$1,925
Balcony
$2,639
Suite
$3,584
From
US$1,680
Save 3,118
Per Person
View Trip
5 Day A Journey Through Riviera Elegance & Coastal Splendour with Explora Journeys
Cruise
 (1)

5 Days (4 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 April 2026
Visit: Spain, Monaco, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$2,640
From
US$2,640
Per Person
View Trip
11 Day Italy & France Spotlight with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 22 May 2026
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,323
Oceanview
$3,565
Balcony
-
Suite
-
From
US$3,323
Save 3,475
Per Person
View Trip
15 Day Maritime Memories In The Med with Oceania Cruises
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 17 January 2028
Visit: Spain, Morocco, Sardinia, Tunisia, Sicily, Malta, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,398
Suite
$7,696
From
US$4,398
Save 4,600
Per Person
View Trip
8 Day Spain & Portugal Cruise: Barcelona, Seville & Lisbon with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 22 May 2027
Visit: Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$2,279
Oceanview
$2,540
Balcony
$3,307
Suite
$5,237
From
US$2,279
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: Apr 2026 to Aug 2026
Visit: France, Italy, Malta, Sicily
All-Inclusive Fare
Last Minute Fare
Inside
-
Oceanview
$6,750
Balcony
$7,250
Suite
$16,000
From
US$6,750
Per Person
View Trip
8 Day A Journey Through Italy's Timeless Wonders to Istanbul's Vibrant Soul with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 04 December 2027
Visit: Italy, Sicily, Greece, Turkey
Inside
-
Oceanview
-
Balcony
-
Suite
$4,420
From
US$4,420
Per Person
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 October 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,000
Suite
$12,500
From
US$9,000
Save 2,500
Per Person
View Trip
15 Day Southern Mediterranean Sojourn with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 07 December 2026
Visit: Spain, France, Italy, Sicily, Tunisia, Malta
Elevate Your Experience
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$13,403
From
US$13,403
Save 13,895
Per Person
View Trip
8 Day Iberian Experience with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 12 September 2027
Visit: Spain, Morocco, Gibraltar, Portugal
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,743
Suite
$4,683
From
US$2,743
Save 2,855
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 20 April 2026
Visit: France, Corsica, Sardinia, Spain
All-Inclusive Fare
Inside
-
Oceanview
$14,200
Balcony
$15,100
Suite
$17,800
From
US$14,200
Per Person
View Trip
13 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Nova
Departure: 21 November 2027
Visit: Italy, France, Spain, Morocco, Portugal
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$10,100
Suite
$13,800
From
US$10,100
Per Person
View Trip
8 Day Rome To Romance with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 April 2028
Visit: Italy, Corsica, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,099
Oceanview
$2,785
Balcony
$3,415
Suite
$4,676
From
US$2,099
Save 2,099
Per Person
View Trip
18 Day Mediterranean & Iberian New Year Cruise: Italy, Spain & Morocco with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Visit: Italy, Spain, Morocco, Portugal
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$5,709
Balcony
-
Suite
$11,151
From
US$5,709
Save 130
Per Person
View Trip
8 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Visit: Spain, France, Italy
Azamara Always Included
Inside
$1,699
Oceanview
$1,949
Balcony
$2,249
Suite
$3,735
From
US$1,699
Per Person
View Trip
8 Day Riviera Reverie with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 30 September 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,275
Suite
$9,716
From
US$9,275
Save 9,623
Per Person
View Trip
22 Day Mediterranean Mosaic: Croatia, Italy, France & Spain with Seabourn
Cruise

22 Days (21 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy (+5 more), Monaco, France, Spain, Corsica, Sardinia
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$20,232
Suite
-
From
US$20,232
Save 367
Per Person
View Trip
13 Day Passage To Portugal with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Monte Carlo to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 12 July 2026
Visit: Monaco, France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Exclusive Savings
Inside
$2,600
Oceanview
$2,803
Balcony
$5,230
Suite
$6,577
From
US$2,600
Save 5,398
Per Person
View Trip
11 Day French Riviera, Corsica and Monaco Grand Prix with Scenic
New ReleaseCruise

11 Days (10 Nights) Nice to Rome
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 30 May 2027
Visit: France, Corsica, Italy, Monaco
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,022
Suite
$19,952
From
US$15,022
Save 1,173
Per Person
View Trip
10 Day Eclipse The Ordinary with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 29 July 2027
Visit: Spain, Malta, Sicily, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$68,617
From
US$68,617
Save 71,381
Per Person
View Trip
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