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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 634 unique cruise itineraries with 1184 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 714 departures starting between March 2026 and October 2028.
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634 Cruises (714 Cruise Departures)
9 Day Historical Cities of the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 01 June 2026
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$7,540
Suite
$14,120
From
US$7,540
Per Person
View Trip
9 Day Greece, Italy & Spain Cruise: Athens, Siracusa & Malaga with Azamara Cruises
Cruise
 (4)

9 Days (8 Nights) Athens to Malaga
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 26 November 2026
Visit: Greece, Sicily, Malta, Tunisia, Spain
Azamara Always Included
Inside
$1,999
Oceanview
$2,338
Balcony
$3,075
Suite
$4,918
From
US$1,999
Per Person
View Trip
10 Day Italian Interlude with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 24 March 2028
Visit: Spain, Sardinia, Sicily, Greece, Croatia, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,545
Oceanview
$2,788
Balcony
$4,291
Suite
$6,134
From
US$2,545
Save 2,653
Per Person
View Trip
5 Day Break Between Provence and Catalonia with Ponant
Cruise
 (1)

5 Days (4 Nights) Nice to Barcelona
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 08 August 2027
Visit: France, Spain
Inside
-
Oceanview
-
Balcony
$3,050
Suite
$5,650
From
US$3,050
Per Person
View Trip
11 Day French Riviera, Corsica and Monaco Grand Prix with Scenic
New ReleaseCruise

11 Days (10 Nights) Nice to Rome
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 30 May 2027
Visit: France, Corsica, Italy, Monaco
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,262
Suite
$17,997
From
US$14,262
Save 18,228
Per Person
View Trip
11 Day Italy & Spain Cruise: Florence, Marseille & Barcelona with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 03 March 2027
Visit: Italy, France, Spain
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Exclusive Savings
Inside
$2,927
Oceanview
$3,363
Balcony
$3,829
Suite
$5,905
From
US$2,927
Save 62
Per Person
View Trip
8 Day Elegant Shores with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 April 2026
Visit: Spain, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,689
Suite
$9,375
From
US$8,689
Save 9,009
Per Person
View Trip
7 Day Barcelona to Monte Carlo with Silversea
Cruise

7 Days (6 Nights) Barcelona to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 24 August 2026
Visit: Spain, France, Italy, Corsica, Monaco
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,830
Suite
$6,100
From
US$4,830
Save 2,070
Per Person
View Trip
8 Day Yachting Havens with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 May 2026
Visit: Spain, France, Italy
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,781
From
US$7,781
Save 8,217
Per Person
View Trip
11 Day Roman Holiday with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 27 November 2027
Visit: Italy, Corsica, France, Spain, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,741
Oceanview
$3,565
Balcony
$4,293
Suite
$6,233
From
US$2,741
Save 2,857
Per Person
View Trip
11 Day Pearls of Southern Spain & Portugal with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 28 September 2026
Visit: Spain, Morocco, Portugal
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$23,505
From
US$23,505
Save 28,885
Per Person
View Trip
9 Day Mediterranean Islands with Seabourn
Cruise

9 Days (8 Nights) Rome to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,050
Suite
$11,578
From
US$8,050
Save 149
Per Person
View Trip
23 Day Spanish Summer with Regent Seven Seas
Cruise

23 Days (22 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 11 August 2027
Visit: Portugal, Spain, Morocco, France (+4 more), Monaco, Italy, Corsica, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$24,006
Suite
$26,701
From
US$24,006
Save 24,892
Per Person
View Trip
11 Day Jewels of the Mediterranean with Scenic
New ReleaseCruise

11 Days (10 Nights) Palma de Mallorca to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 May 2027
Visit: Spain, Sardinia, Sicily, Malta
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,671
Suite
$17,637
From
US$11,671
Save 15,319
Per Person
View Trip
15 Day Croatia, Montenegro, Italy, Monaco & France with Seabourn
Cruise

15 Days (14 Nights) Dubrovnik to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy, Monaco, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,083
Suite
$19,335
From
US$12,083
Save 216
Per Person
View Trip
11 Day Icons Of Antiquity with Regent Seven Seas
Cruise

11 Days (10 Nights) Istanbul to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 30 September 2027
Visit: Turkey, Greece, Cyprus, Israel, Egypt
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,195
Suite
$12,469
From
US$11,195
Save 11,603
Per Person
View Trip
18 Day Discover the Mediterranean from Cannes to Athens with Emerald Cruises
New ReleaseCruise
 (3)

18 Days (17 Nights) Nice to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 25 April 2026
Visit: France, Italy, Corsica, Sicily, Malta, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$37,042
From
US$37,042
Save 1,088
Per Person
View Trip
8 Day Grecian & Roman Gems with Seabourn
Cruise
 (1)

8 Days (7 Nights) Athens to Rome
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 25 October 2026
Visit: Greece, Albania, Italy
Exclusive Savings
Inside
-
Oceanview
$6,805
Balcony
$8,540
Suite
$13,048
From
US$6,805
Save 124
Per Person
View Trip
18 Day Mediterranean Mystique with Regent Seven Seas
Cruise

18 Days (17 Nights) Athens to Monte Carlo
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 19 June 2026
Visit: Greece, Malta, Sicily, Tunisia (+5 more), Spain, Portugal, Morocco, France, Monaco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$22,338
Suite
-
From
US$22,338
Save 23,160
Per Person
View Trip
8 Day Culinary Capitals with Regent Seven Seas
Cruise

8 Days (7 Nights) Lisbon to Monte Carlo
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 29 June 2026
Visit: Portugal, Spain, Morocco, France, Monaco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,623
Suite
-
From
US$9,623
Save 9,975
Per Person
View Trip
12 Day Mediterranean Cruise: Greece, Turkey & Italy with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Athens to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 02 August 2026
Visit: Greece, Turkey, Sicily, Italy, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$3,275
Oceanview
$3,711
Balcony
$4,380
Suite
$7,853
From
US$3,275
Save 74
Per Person
View Trip
18 Day Grand Mediterranean Jewels with Oceania Cruises
Cruise

18 Days (17 Nights) Tarragona to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 October 2026
Visit: Spain, France, Italy, Sicily, Malta, Tunisia, Sardinia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,018
Suite
$12,364
From
US$9,018
Save 9,480
Per Person
View Trip
22 Day Discover the Wonders of the Mediterranean with Emerald Cruises
New ReleaseCruise
 (3)

22 Days (21 Nights) Athens to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 17 October 2026
Visit: Greece, Sicily, Malta, Italy (+4 more), Corsica, Spain, Morocco, Portugal
Fly Free Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$23,049
From
US$23,049
Save 24,601
Per Person
View Trip
7 Day Monte Carlo to Barcelona with Silversea
Cruise

7 Days (6 Nights) Monte Carlo to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 30 August 2026
Visit: Monaco, France, Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,760
Suite
$6,650
From
US$4,760
Save 2,040
Per Person
View Trip
24 Day Coastal Harmony with Regent Seven Seas
Cruise

24 Days (23 Nights) Lisbon to Istanbul
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 17 October 2027
Visit: Portugal, Spain, Morocco, France (+6 more), Monaco, Italy, Corsica, Croatia, Greece, Turkey
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,705
Suite
$23,861
From
US$21,705
Save 22,493
Per Person
View Trip
8 Day Rome to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,880
Suite
$4,640
From
US$4,640
Save 4,160
Per Person
View Trip
10 Day Ancient Athenian Adventure with Oceania Cruises
Cruise

10 Days (9 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 18 March 2028
Visit: Greece, Montenegro, Croatia, Malta, Sicily, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,516
Suite
$6,038
From
US$3,516
Save 3,682
Per Person
View Trip
10 Day Ancient Shores of the Mediterranean with Ponant
Cruise
 (2)

10 Days (9 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 05 May 2026
Visit: Spain, Algeria, Tunisia, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$8,560
Suite
$16,050
From
US$8,560
Per Person
View Trip
15 Day An Extended Journey From Italian Gems To Riviera Delights with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 May 2026
Visit: Italy, Sicily, Tunisia, Spain, France, Sardinia
Inside
-
Oceanview
-
Balcony
-
Suite
$10,480
From
US$10,480
Per Person
View Trip
13 Day Best Of The Mediterranean Cruise: Crete, Sicily, Corsica & Majorca with Azamara Cruises
Cruise
 (3)

13 Days (12 Nights) Athens to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 19 October 2027
Visit: Greece, Sicily, Malta, Tunisia (+4 more), Sardinia, France, Corsica, Spain
Azamara Always Included
Exclusive Savings
Inside
$4,517
Oceanview
$4,963
Balcony
$5,953
Suite
$8,378
From
US$4,517
Save 112
Per Person
View Trip
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