Home > Cruises > Europe Cruises > Mediterranean Cruises > Luxury Cruises

Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
Filter Results
Departures
Show More...
Duration
5 Days
63 Days
Start & End Cities
Ship Size
Cruise Lines
Show More...
Price
$600pp
$65,399pp
Countries
Show More...
Filter Results
780 Cruises (900 Cruise Departures)
9 Day Historical Cities of the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 01 June 2026
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$7,540
Suite
$14,120
From
US$7,540
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 22 June 2026
Visit: Spain, Sardinia, Corsica, Sicily, Italy
Inside
$799
Oceanview
$899
Balcony
$1,199
Suite
$2,359
From
US$799
Per Person
View Trip
6 Day Sicilian interlude with Ponant
Cruise
 (2)

6 Days (5 Nights) Palermo to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 June 2027
Visit: Sicily, Italy, Malta
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
17 Day France & Italy Combination Cruise: Saint-tropez, Portofino & Florence with Azamara Cruises
Cruise
 (5)

17 Days (16 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 23 September 2028
Visit: Spain, France, Corsica, Italy, Sardinia
Azamara Always Included
Inside
$4,029
Oceanview
$4,369
Balcony
$5,369
Suite
$7,599
From
US$4,029
Per Person
View Trip
11 Day Spain Intensive Cruise: Seville, Malaga & Valencia with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 13 September 2028
Visit: Portugal, Spain, Gibraltar
Azamara Always Included
Inside
$2,519
Oceanview
$2,739
Balcony
$3,369
Suite
$4,759
From
US$2,519
Per Person
View Trip
15 Day Mediterranean Combination Cruise: Nice, La Spezia & Athens with Azamara Cruises
Cruise
 (8)

15 Days (14 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Visit: Spain, France, Italy, Sicily, Greece
Azamara Always Included
Inside
$2,839
Oceanview
$3,119
Balcony
$3,579
Suite
$5,589
From
US$2,839
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy, France
Inside
$2,809
Oceanview
$2,869
Balcony
$4,329
Suite
$5,469
From
US$2,809
Per Person
View Trip
8 Day Greece And Turkiye with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 26 May 2028
Visit: Italy, Sicily, Greece, Turkey
Cunard Fare
Value Fare
Inside
$1,819
Oceanview
$1,909
Balcony
$2,359
Suite
$4,564
From
US$1,819
Per Person
View Trip
8 Day Rome to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,400
Suite
$7,400
From
US$4,400
Save 4,000
Per Person
View Trip
8 Day Isle of Beauty and Iberian shores with Ponant
Cruise
 (2)

8 Days (7 Nights) Nice to Malaga
Cruise Line: Ponant
Ship: Le Boreal
Departure: 23 June 2027
Visit: France, Corsica, Spain
Inside
-
Oceanview
$5,200
Balcony
$5,480
Suite
$10,170
From
US$5,200
Per Person
View Trip
9 Day Tribute to Maria Callas with Ponant
Cruise
 (2)

9 Days (8 Nights) Athens to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 29 September 2027
Visit: Greece, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$9,230
Suite
$17,350
From
US$9,230
Per Person
View Trip
20 Day Discover the Beauty of the Mediterranean with Emerald Cruises
New ReleaseCruise
 (3)

20 Days (19 Nights) Lisbon to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 30 April 2027
Visit: Portugal, Spain, Morocco, Sardinia (+4 more), Corsica, Italy, Sicily, Malta
Inside
-
Oceanview
$20,290
Balcony
-
Suite
-
From
US$20,290
Per Person
View Trip
11 Day Italy, France & Spain Cruise: Florence, Marseille & Barcelona with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 17 July 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Inside
$3,839
Oceanview
$3,719
Balcony
$4,879
Suite
$7,839
From
US$3,719
Per Person
View Trip
10 Day Italy & Spain Cruise: Florence, Portofino & Barcelona with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 August 2026
Visit: Spain, France, Monaco, Italy
Azamara Always Included
Inside
$2,599
Oceanview
$3,069
Balcony
$4,129
Suite
$4,509
From
US$2,599
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 September 2028
Visit: Spain, France, Corsica, Italy
Cunard Fare
Value Fare
Inside
$1,639
Oceanview
$1,774
Balcony
$2,134
Suite
$4,159
From
US$1,639
Per Person
View Trip
8 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Visit: Spain, France, Italy
Azamara Always Included
Inside
$1,549
Oceanview
$1,679
Balcony
$1,609
Suite
$2,669
From
US$1,549
Per Person
View Trip
16 Day Italy, France & Spain Cruise: Rome, Barcelona & Seville with Azamara Cruises
Cruise
 (3)

16 Days (15 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 December 2027
Visit: Italy, France, Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$3,629
Oceanview
$4,549
Balcony
$5,739
Suite
$8,609
From
US$3,629
Per Person
View Trip
11 Day Lisbon to Civitavecchia (Rome) with Silversea
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 06 April 2027
Visit: Portugal, Spain, France, Italy
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,200
Suite
$12,000
From
US$7,200
Save 2,500
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Florence & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 May 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Inside
$1,919
Oceanview
$2,209
Balcony
$2,919
Suite
$4,709
From
US$1,919
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 September 2028
Visit: Spain, France, Corsica, Italy (+4 more), Malta, Croatia, Greece, Sicily
Cunard Fare
Value Fare
Inside
$4,364
Oceanview
$4,859
Balcony
$5,939
Suite
$10,169
From
US$4,364
Per Person
View Trip
10 Day Spain Intensive Cruise: Seville, Malaga & Valencia with Azamara Cruises
Cruise
 (3)

10 Days (9 Nights) Lisbon to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 06 September 2028
Visit: Portugal, Spain, Gibraltar
Azamara Always Included
Inside
$2,269
Oceanview
$2,479
Balcony
$3,039
Suite
$4,289
From
US$2,269
Per Person
View Trip
9 Day Peaceful Islands and Ancient Treasures of the Mediterranean with Ponant
Cruise
 (2)

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 17 August 2027
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$6,910
Suite
$12,870
From
US$6,910
Per Person
View Trip
9 Day Isle of Beauty & Italian shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 August 2026
Visit: France, Corsica, Italy
Inside
-
Oceanview
$6,520
Balcony
$7,220
Suite
$14,580
From
US$6,520
Per Person
View Trip
11 Day A Journey To Santorini, Sicily & The Riviera with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Athens to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 November 2026
Visit: Greece, Malta, Sicily, Italy, France, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,360
From
US$5,360
Per Person
View Trip
8 Day Spain, France & Italy Cruise: Barcelona, Nice & Portovenere with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 02 June 2028
Visit: Spain, France, Italy
Azamara Always Included
Inside
$2,049
Oceanview
$2,329
Balcony
$2,729
Suite
$4,129
From
US$2,049
Per Person
View Trip
10 Day Epicurean Odyssey with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 27 September 2027
Visit: Spain, France, Monaco, Italy, Corsica, Sardinia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,499
Oceanview
$2,749
Balcony
$4,549
Suite
$6,299
From
US$2,499
Save 2,499
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 25 August 2028
Visit: Spain, France, Italy
Cunard Fare
Value Fare
Inside
$1,639
Oceanview
$1,774
Balcony
$2,179
Suite
$4,159
From
US$1,639
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 02 July 2027
Visit: Italy, Spain, France, Corsica
Bonus Onboard Credit
Value Fare
Inside
$1,199
Oceanview
$1,299
Balcony
$1,439
Suite
$2,939
From
US$1,199
Per Person
View Trip
12 Day Italy Intensive Cruise: Florence, Sorrento & Sicily with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 September 2027
Visit: France, Italy, Sicily, Montenegro
Azamara Always Included
Inside
$5,119
Oceanview
$5,719
Balcony
$6,879
Suite
$9,869
From
US$5,119
Per Person
View Trip
40 Day Athens To Lisbon Grand Voyage with Azamara Cruises
Cruise
 (3)

40 Days (39 Nights) Athens to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 February 2028
Visit: Greece, Egypt, Cyprus, Turkey (+6 more), Sicily, Italy, France, Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$10,839
Oceanview
$12,239
Balcony
$15,439
Suite
$22,639
From
US$10,839
Per Person
View Trip
Results: 1-30 of 780

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Luxury Cruises Short Cruise Breaks

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations