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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 463 unique cruise itineraries from 10 leading cruise lines. September is the most popular month to join a luxury cruise in the Mediterranean with 562 departures starting between May 2024 and April 2027.
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463 Cruises (562 Cruise Departures)
10 Day Cities Of The Western Med Voyage with Azamara Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 31 October 2024
Countries Visited: Italy, Monaco, France, Spain
Circle Club Voyage
INSIDE
-
OCEANVIEW
$2,205
BALCONY
$4,228
SUITE
$5,512
From 2,205
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Trip Styles: Group, Cruise
Countries Visited: Malta, Sicily, Italy
From 18,940
View Trip
22 Day Greece, Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 23 June 2025
Countries Visited: Italy, Greece, Montenegro, Croatia (+4 more), Malta, Spain, Corsica, France
INSIDE
$4,234
OCEANVIEW
$4,550
BALCONY
$5,352
SUITE
$11,055
From 4,234
View Trip
8 Day A Journey From Civitavecchia To Barcelona with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Jul 2025
Countries Visited: Italy, Sicily, Sardinia, Spain
INSIDE
-
OCEANVIEW
-
BALCONY
$6,534
SUITE
$7,945
From 5,940
View Trip
10 Day Rome to Nice with Silversea
Cruise

10 Days (9 Nights) Rome to Nice
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 10 September 2024
Countries Visited: France, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$13,662
BALCONY
$15,642
SUITE
-
From 13,662
View Trip
8 Day Yachting Gems of the French and Italian Rivieras with Emerald Cruises
New ReleaseCruise

8 Days (7 Nights) Nice to Barcelona
Cruise Line: Emerald Cruises
Ships: Emerald Sakara
Departures: Oct 2025 to Aug 2026
Countries Visited: France, Italy, Corsica, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,480
BALCONY
-
SUITE
$8,791
Save 1,576
From 6,480
View Trip
8 Day Mediterranean Escapade: Spain & the French Riviera with Scenic
Cruise

8 Days (7 Nights) Barcelona to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 29 April 2025
Countries Visited: Spain, France, Corsica
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,351
SUITE
$14,068
Save 2,094
From 9,351
View Trip
11 Day A Journey From Athens To Barcelona with Explora Journeys
Cruise

11 Days (10 Nights) Athens to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 31 October 2024
Countries Visited: Greece, Malta, Italy, France (+1 more), Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,311
SUITE
$11,380
From 5,881
View Trip
12 Day Barcelona to Rome with Silversea
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 26 April 2025
Countries Visited: Spain, France, Italy, Monaco
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,553
From 14,553
View Trip
13 Day Tyrrhenian Treasures & Malta with Seabourn
Cruise

13 Days (12 Nights) Monte Carlo to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 10 September 2024
Countries Visited: Monaco, Italy, Sicily, Malta (+3 more), Corsica, France, Spain
More Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$19,810
From 19,810
View Trip
11 Day Flair, Flavor & Culture with Regent Seven Seas
Cruise

11 Days (10 Nights) Monte Carlo to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 April 2025
Countries Visited: Monaco, Italy, Turkey, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,545
SUITE
$11,396
Save 7,685
From 9,545
View Trip
21 Day Spain, Morocco & Mediterranean Magic with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Monte Carlo
Cruise Line: Seabourn
Ship: Ovation
Departure: 01 July 2025
Countries Visited: Spain, France, Gibraltar, Morocco (+2 more), Sardinia, Italy
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$16,259
SUITE
$28,713
From 16,259
View Trip
17 Day Barcelona to Civitavecchia with Silversea
Cruise

17 Days (16 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 06 July 2025
Countries Visited: Spain, France, Monaco, Italy (+1 more), Sicily
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,513
From 18,513
View Trip
8 Day France Intensive Voyage with Azamara Cruises
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 06 July 2024
Countries Visited: Monaco, France, Spain
Circle Club Voyage
INSIDE
$2,152
OCEANVIEW
$3,017
BALCONY
$2,979
SUITE
$5,736
From 2,152
View Trip
8 Day Mediterranean Rivieras with Azamara Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 18 August 2024
Countries Visited: Italy, France, Spain
Circle Club Voyage
INSIDE
$1,858
OCEANVIEW
$2,079
BALCONY
$3,206
SUITE
$3,910
From 1,857
View Trip
11 Day A Journey From Barcelona To Athens with Explora Journeys
Cruise

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 18 April 2025
Countries Visited: Spain, Sicily, Malta, Greece (+1 more), Turkey
INSIDE
-
OCEANVIEW
-
BALCONY
$10,063
SUITE
$12,321
From 9,534
View Trip
17 Day Civitavecchia to Barcelona with Silversea
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 September 2025
Countries Visited: Italy, Sicily, Tunisia, France (+1 more), Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,909
From 18,909
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 07 June 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$8,890
Save 2,090
From 8,890
View Trip
17 Day Discover Malta, Italy & France with Emerald Cruises
New ReleaseCruise

17 Days (16 Nights) Valletta to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 05 May 2026
Countries Visited: Malta, Sicily, Italy, Corsica (+2 more), Monaco, France
Exclusive Deal
INSIDE
-
OCEANVIEW
$16,672
BALCONY
-
SUITE
$22,810
Save 5,168
From 16,672
View Trip
10 Day Barcelona to Monte Carlo with Silversea
Cruise

10 Days (9 Nights) Barcelona to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departures: Jul 2025 to Aug 2025
Countries Visited: Spain, France, Monaco
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,593
From 10,593
View Trip
12 Day Europe - Greek Isles & Eastern Med with Silversea
Cruise

12 Days (11 Nights) Athens to Athens
Cruise Line: Silversea
Ship: Silver Moon
Departure: 20 June 2024
Countries Visited: Cyprus, Egypt, Greece, Israel (+1 more), Turkey
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$11,632
BALCONY
$12,523
SUITE
$24,750
From 11,632
View Trip
13 Day Spring Med & Grand Prix Voyage with Azamara Cruises
Cruise

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 20 May 2025
Countries Visited: Italy, Corsica, France, Spain (+2 more), Gibraltar, Portugal
INSIDE
$7,033
OCEANVIEW
$7,493
BALCONY
$8,183
SUITE
$10,252
From 7,033
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 July 2024
Countries Visited: Italy, France, Spain, Sardinia (+2 more), Corsica, Sicily
INSIDE
$2,895
OCEANVIEW
$3,192
BALCONY
$3,677
SUITE
$7,686
From 2,895
View Trip
17 Day Civitavecchia to Barcelona with Silversea
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 22 July 2025
Countries Visited: Italy, Sicily, Monaco, France (+1 more), Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,513
From 18,513
View Trip
13 Day Mediterranean Melody with Oceania Cruises
Cruise

13 Days (12 Nights) Barcelona to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 September 2025
Countries Visited: Spain, France, Monaco, Italy (+3 more), Sicily, Greece, Turkey
Exclusive Deal
INSIDE
$6,926
OCEANVIEW
$8,154
BALCONY
$9,371
SUITE
$12,539
Save 2,054
From 6,926
View Trip
10 Day Spanish Shores & Beyond with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Palma de Mallorca to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 19 September 2026
Countries Visited: Spain, Sardinia, Corsica, Monaco (+1 more), France
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,143
BALCONY
-
SUITE
$13,657
Save 2,102
From 10,143
View Trip
30 Day Iberian Coast, Riviera Gems & Mediterranean Magic with Seabourn
Cruise

30 Days (29 Nights) Lisbon to Monte Carlo
Cruise Line: Seabourn
Ship: Ovation
Departure: 27 March 2025
Countries Visited: Portugal, Spain, France, Corsica (+3 more), Italy, Monaco, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$24,348
SUITE
-
From 24,348
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 12 November 2024
Countries Visited: Italy, Spain, Tunisia, Malta
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,187
From 11,187
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Jun 2024 to Sep 2024
Countries Visited: Italy, France, Spain
INSIDE
$1,882
OCEANVIEW
$2,179
BALCONY
$2,377
SUITE
$4,753
From 1,882
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2026 to Jun 2026
Countries Visited: Spain, Corsica, Sicily, Italy
INSIDE
$1,387
OCEANVIEW
$1,585
BALCONY
$1,783
SUITE
$3,763
From 1,387
View Trip
Results: 31-60 of 463

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