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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 745 unique cruise itineraries with 1204 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 848 departures starting between April 2026 and November 2028.
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745 Cruises (848 Cruise Departures)
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Visit: Spain, Corsica, Italy, Malta, Montenegro, Croatia
Bonus Onboard Credit
Inside
$2,049
Oceanview
$2,459
Balcony
$2,779
Suite
$5,869
From
US$2,049
Per Person
View Trip
11 Day Visions Of Byzantium with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 17 August 2026
Visit: Spain, Sicily, Greece, Turkey
Your World Inclusions
Exclusive Savings
Inside
$2,400
Oceanview
$2,662
Balcony
$3,975
Suite
$4,912
From
US$2,400
Save 3,998
Per Person
View Trip
10 Day Italian Interlude with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 24 March 2028
Visit: Spain, Sardinia, Sicily, Greece, Croatia, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,599
Oceanview
$2,849
Balcony
$4,399
Suite
$6,299
From
US$2,599
Save 2,599
Per Person
View Trip
11 Day Spain Intensive Voyage with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 07 November 2026
Visit: Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$3,539
Oceanview
$4,079
Balcony
$4,499
Suite
$6,709
From
US$3,539
Per Person
View Trip
9 Day 2026 Grand Prix Cruise: Nice, Portofino & Florence with Azamara Cruises
Cruise
 (3)

9 Days (8 Nights) Nice to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 02 June 2026
Visit: France, Italy, Spain
Azamara Always Included
Inside
$1,439
Oceanview
$1,549
Balcony
$2,269
Suite
-
From
US$1,439
Per Person
View Trip
8 Day Spain & Portugal Cruise: Barcelona, Seville & Lisbon with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 22 May 2027
Visit: Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$2,279
Oceanview
$2,599
Balcony
$3,389
Suite
$5,379
From
US$2,279
Per Person
View Trip
20 Day Rome, Ruins & Gondola Rides with Oceania Cruises
Cruise
 (1)

20 Days (19 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 July 2027
Visit: Italy, Sicily, Greece, Turkey, Albania, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$5,899
Oceanview
$6,399
Balcony
$9,699
Suite
$13,599
From
US$5,899
Save 5,899
Per Person
View Trip
10 Day Exploring Ancient Empires with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 29 March 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Inclusions
Exclusive Savings
Inside
$2,399
Oceanview
$2,649
Balcony
$4,199
Suite
$6,099
From
US$2,399
Save 2,399
Per Person
View Trip
8 Day Greece, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia
Inside
$1,409
Oceanview
$1,609
Balcony
$1,909
Suite
$4,059
From
US$1,409
Per Person
View Trip
11 Day Lisbon to Rome with Silversea
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 14 June 2026
Visit: Portugal, Spain, France, Monaco, Italy
Last Minute Fare
All-Inclusive Plus Fare
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$6,950
Suite
$13,600
From
US$6,950
Per Person
View Trip
15 Day Italy, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 May 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Bonus Onboard Credit
Inside
$2,539
Oceanview
$2,719
Balcony
$2,879
Suite
$6,139
From
US$2,539
Per Person
View Trip
11 Day Iberian Peninsula and Mediterranean jewels with Ponant
Cruise
 (2)

11 Days (10 Nights) Lisbon to Valletta
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 07 August 2027
Visit: Portugal, Spain, Sardinia, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$7,650
Suite
$14,170
From
US$7,650
Per Person
View Trip
12 Day Italy Cruise: Florence, Rome & Sorrento with Azamara Cruises
Cruise
 (5)

12 Days (11 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 13 September 2026
Visit: Spain, France, Monaco, Italy, Sicily, Montenegro, Slovenia
Azamara Always Included
Inside
$3,239
Oceanview
$3,739
Balcony
$5,889
Suite
-
From
US$3,239
Per Person
View Trip
10 Day Italy & Greece Cruise: Amalfi, Crete & Santorini with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 August 2027
Visit: Italy, Sicily, Greece, Turkey
Azamara Always Included
Inside
$4,149
Oceanview
$4,699
Balcony
$5,749
Suite
$8,399
From
US$4,149
Per Person
View Trip
8 Day Italy And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Visit: Spain, Sardinia, Sicily, Italy
Bonus Onboard Credit
Inside
$1,519
Oceanview
$1,449
Balcony
$1,539
Suite
$2,889
From
US$1,449
Per Person
View Trip
15 Day Italy, Spain And Adriatic with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Jun 2026 to Aug 2026
Visit: Italy, Greece, Montenegro, Croatia, Malta, Spain
Bonus Onboard Credit
Inside
$2,499
Oceanview
$2,649
Balcony
$2,759
Suite
$6,119
From
US$2,499
Per Person
View Trip
6 Day Springtime Along the Mediterranean with Ponant
Cruise
 (2)

6 Days (5 Nights) Nice to Rome
Cruise Line: Ponant
Ship: Le Boreal
Departure: 07 May 2027
Visit: France, Monaco, Italy, Corsica
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
8 Day Mount Etna To Lake Bled with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 29 July 2027
Visit: Italy, Sicily, Greece, Croatia, Slovenia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,099
Oceanview
$2,399
Balcony
$3,699
Suite
$5,199
From
US$2,099
Save 2,099
Per Person
View Trip
36 Day Rome To Dublin Grand Voyage with Azamara Cruises
Cruise
 (3)

36 Days (35 Nights) Rome to Dublin
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 May 2027
Visit: Italy, Monaco, France, Spain (+5 more), Gibraltar, Portugal, England, Scotland, Ireland
Azamara Always Included
Inside
$10,799
Oceanview
$12,019
Balcony
$15,119
Suite
-
From
US$10,799
Per Person
View Trip
6 Day An Autumn Escape: Côte d’Azur, Italian Riviera & Corsica with Ponant
Cruise
 (2)

6 Days (5 Nights) Nice to Florence
Cruise Line: Ponant
Ship: Le Boreal
Departure: 28 September 2027
Visit: France, Italy, Corsica
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
32 Day Mediterranean Cruise: Italy, Croatia & Greece with Azamara Cruises
Cruise
 (5)

32 Days (31 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 13 September 2026
Visit: Spain, France, Monaco, Italy (+6 more), Sicily, Montenegro, Slovenia, Croatia, Greece, Turkey
Azamara Always Included
Inside
$10,729
Oceanview
$12,669
Balcony
-
Suite
-
From
US$10,729
Per Person
View Trip
8 Day Authentic Mediterranean Shores with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: Ponant
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2027 to May 2027
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$5,690
Suite
$10,580
From
US$5,690
Per Person
View Trip
12 Day Best Of The Mediterranean Cruise: Portofino, Florence & Kotor with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Monte Carlo to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 18 June 2026
Visit: Monaco, Italy, Montenegro, Croatia, Slovenia
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$2,229
Oceanview
$2,579
Balcony
-
Suite
-
From
US$2,229
Per Person
View Trip
10 Day Trojan Trek Revisited with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 July 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,899
Oceanview
$3,149
Balcony
$4,799
Suite
$6,699
From
US$2,899
Save 2,899
Per Person
View Trip
11 Day Charming Mediterranean with Emerald Cruises
Cruise
 (3)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 30 April 2027
Visit: Portugal, Spain, Sardinia, Corsica, Italy
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$8,392
Balcony
-
Suite
$11,182
From
US$8,392
Save 1,903
Per Person
View Trip
15 Day Spain, Italy And Morocco with Cunard
Cruise
 (1)

15 Days (14 Nights) London to London
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 May 2027
Visit: England, Morocco, Spain, Italy, France
Bonus Onboard Credit
Inside
$2,649
Oceanview
$2,949
Balcony
$4,049
Suite
$8,749
From
US$2,649
Per Person
View Trip
8 Day Spain Intensive: Malaga, Valencia & Barcelona with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Malaga to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 February 2027
Visit: Spain, Morocco
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$1,739
Oceanview
$1,999
Balcony
$2,279
Suite
$3,649
From
US$1,739
Per Person
View Trip
9 Day Tribute to Maria Callas with Ponant
Cruise
 (2)

9 Days (8 Nights) Athens to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 29 September 2027
Visit: Greece, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$9,230
Suite
$16,470
From
US$9,230
Per Person
View Trip
8 Day Mediterranean Passage with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 December 2026
Visit: Italy, Corsica, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$1,837
Balcony
$2,475
Suite
$3,375
From
US$1,837
Save 3,061
Per Person
View Trip
13 Day Best Of The Mediterranean Cruise: Monte Carlo, Florence & Venice with Azamara Cruises
Cruise
 (8)

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 08 June 2027
Visit: Spain, France, Monaco, Italy, Montenegro, Croatia, Slovenia
Azamara Always Included
Inside
$5,329
Oceanview
$5,939
Balcony
$7,329
Suite
$10,609
From
US$5,329
Per Person
View Trip
Results: 31-60 of 745

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