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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 614 unique cruise itineraries with 1183 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 677 departures starting between March 2026 and October 2028.
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614 Cruises (677 Cruise Departures)
8 Day Greco-roman World with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departures: May 2027 to Aug 2027
Visit: Greece, Sicily, Malta, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,883
Suite
$4,677
From
US$2,883
Save 3,118
Per Person
View Trip
12 Day Heavenly Islands & Iberian Shores with Ponant
Cruise

12 Days (11 Nights) Barcelona to Porto
Cruise Line: Ponant
Ship: Le Champlain
Departure: 06 May 2026
Visit: Spain, Portugal
Inside
-
Oceanview
-
Balcony
$11,440
Suite
$21,490
From
US$11,440
Per Person
View Trip
8 Day Isle of Beauty and Iberian shores with Ponant
Cruise
 (2)

8 Days (7 Nights) Nice to Malaga
Cruise Line: Ponant
Ship: Le Boreal
Departure: 23 June 2027
Visit: France, Corsica, Spain
Inside
-
Oceanview
$5,200
Balcony
$5,480
Suite
$10,170
From
US$5,200
Per Person
View Trip
21 Day Discover the Yachting Treasures of the Mediterranean with Emerald Cruises
New ReleaseCruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Visit: Spain, Morocco, Corsica, Sardinia, Sicily, Malta
Fly Free Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$21,266
From
US$21,266
Save 22,514
Per Person
View Trip
9 Day Peaceful Islands and Ancient Treasures of the Mediterranean with Ponant
Cruise
 (2)

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 17 August 2027
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$6,510
Suite
$12,100
From
US$6,510
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Florence, Nice & Barcelona with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 27 May 2027
Visit: Italy, France, Spain
Azamara Always Included
Inside
$2,099
Oceanview
$2,347
Balcony
$3,084
Suite
$4,917
From
US$2,099
Per Person
View Trip
11 Day Fall In The Roman Empire with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 08 October 2027
Visit: Spain, France, Monaco, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,033
Oceanview
$3,857
Balcony
$4,585
Suite
$6,525
From
US$3,033
Save 3,165
Per Person
View Trip
19 Day Mediterranean & North Africa Voyage: Portugal, Morocco & Italy with Azamara Cruises
Cruise
 (8)

19 Days (18 Nights) Lisbon to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 17 November 2026
Visit: Portugal, Morocco, Spain, Gibraltar, France, Italy
Azamara Always Included
Exclusive Savings
Inside
$4,483
Oceanview
$4,929
Balcony
$6,044
Suite
$9,507
From
US$4,483
Save 86
Per Person
View Trip
11 Day Mediterranean & Egypt Cruise: Alexandria, Heraklion & Rome with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 December 2026
Visit: Greece, Egypt, Malta, Sicily, Italy
Azamara Always Included
Inside
$2,329
Oceanview
$2,633
Balcony
$3,021
Suite
$4,786
From
US$2,329
Per Person
View Trip
13 Day Passage To Portugal with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Monte Carlo to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 12 July 2026
Visit: Monaco, France, Spain, Gibraltar, Morocco, Portugal
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$3,521
Oceanview
$3,870
Balcony
$5,878
Suite
$7,886
From
US$3,521
Save 4,477
Per Person
View Trip
11 Day Hidden Gems of the Western Mediterranean with Ponant
Cruise
 (1)

11 Days (10 Nights) Nice to Barcelona
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 21 June 2027
Visit: France, Italy, Corsica, Spain
Inside
-
Oceanview
-
Balcony
$7,650
Suite
$14,170
From
US$7,650
Per Person
View Trip
18 Day Mediterranean & Egypt Cruise: Italy, Greece & Malta with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 December 2026
Visit: Italy, Sicily, Greece, Egypt, Malta
Azamara Always Included
Exclusive Savings
Inside
$3,825
Oceanview
$4,339
Balcony
$5,009
Suite
$8,035
From
US$3,825
Save 74
Per Person
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Muse
Departure: 31 July 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$5,840
Balcony
$6,400
Suite
$9,490
From
US$5,840
Save 1,460
Per Person
View Trip
9 Day Tribute to Maria Callas with Ponant
Cruise
 (2)

9 Days (8 Nights) Athens to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 29 September 2027
Visit: Greece, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$8,780
Suite
$16,470
From
US$8,780
Per Person
View Trip
10 Day Best Of The Mediterranean Cruise: La Goulette, Valletta & Siracusa with Azamara Cruises
Cruise
 (3)

10 Days (9 Nights) Malaga to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 29 January 2028
Visit: Spain, Algeria, Tunisia, Malta, Sicily, Greece
Azamara Always Included
Exclusive Savings
Inside
$2,551
Oceanview
$3,017
Balcony
$3,783
Suite
$5,403
From
US$2,551
Save 58
Per Person
View Trip
8 Day Nice to Palma De Mallorca with Silversea
Cruise

8 Days (7 Nights) Nice to Palma de Mallorca
Cruise Line: Silversea
Ship: Silver Shadow
Departures: May 2026 to Jul 2026
Visit: France, Corsica, Sardinia, Spain
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$4,440
Balcony
$5,040
Suite
$8,700
From
US$4,440
Save 5,400
Per Person
View Trip
9 Day Wandering the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Athens to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 31 July 2027
Visit: Greece, Sicily, Italy, Corsica, France
Inside
-
Oceanview
-
Balcony
$6,120
Suite
$11,340
From
US$6,120
Per Person
View Trip
11 Day Eastbound Adventure with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 18 October 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,031
Oceanview
$3,855
Balcony
$4,583
Suite
$6,523
From
US$3,031
Save 3,167
Per Person
View Trip
9 Day Croatia, Montenegro, Italy & Greece with Seabourn
Cruise

9 Days (8 Nights) Dubrovnik to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 06 August 2027
Visit: Croatia, Montenegro, Italy, Greece
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,102
Suite
$10,843
From
US$7,102
Save 130
Per Person
View Trip
8 Day Relaxation & Romance with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 01 April 2028
Visit: Spain, France, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,660
Suite
$5,163
From
US$3,660
Save 3,838
Per Person
View Trip
8 Day Culinary Capitals with Regent Seven Seas
Cruise

8 Days (7 Nights) Lisbon to Monte Carlo
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 29 June 2026
Visit: Portugal, Spain, Morocco, France, Monaco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,075
Suite
$7,810
From
US$7,075
Save 11,723
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 July 2026
Visit: Italy, France, Corsica, Spain
Inside
$1,429
Oceanview
$1,359
Balcony
$1,659
Suite
$2,879
From
US$1,359
Per Person
View Trip
8 Day Italy, Malta, Croatia & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 08 May 2027
Visit: Italy, Sicily, Malta, Croatia, Montenegro
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,093
Suite
$11,632
From
US$6,093
Save 111
Per Person
View Trip
11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2027
Visit: Italy, France, Spain, Portugal
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,430
Oceanview
$2,647
Balcony
$3,956
Suite
$5,440
From
US$2,430
Save 2,968
Per Person
View Trip
11 Day Spanish Sapphire Shores with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 24 March 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,642
Suite
$10,161
From
US$8,642
Save 14,356
Per Person
View Trip
18 Day Mediterranean & Iberian New Year Cruise: Italy, Spain & Morocco with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Visit: Italy, Spain, Morocco, Portugal
Azamara Always Included
Exclusive Savings
Inside
$4,623
Oceanview
$5,438
Balcony
$6,427
Suite
$10,424
From
US$4,623
Save 96
Per Person
View Trip
23 Day Mediterranean Mosaic: Italy, Croatia & Greece with Seabourn
Cruise

23 Days (22 Nights) Genoa to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 April 2027
Visit: Italy, Corsica, Sardinia, Tunisia (+5 more), Sicily, Malta, Croatia, Montenegro, Greece
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,954
Suite
$33,197
From
US$16,954
Save 300
Per Person
View Trip
8 Day Monte Carlo to Monte Carlo with Silversea
Cruise

8 Days (7 Nights) Monte Carlo to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 14 August 2027
Visit: Monaco, Italy, Sardinia, Corsica, France
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,640
Suite
$7,520
From
US$4,640
Save 1,160
Per Person
View Trip
8 Day Grecian & Roman Gems with Seabourn
Cruise
 (1)

8 Days (7 Nights) Athens to Rome
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 25 October 2026
Visit: Greece, Albania, Italy
Explore More
Exclusive Savings
Inside
-
Oceanview
$5,595
Balcony
$7,261
Suite
$11,093
From
US$5,595
Save 99
Per Person
View Trip
12 Day Mediterranean Cruise: Greece, Italy & France with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Athens to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 10 May 2026
Visit: Greece, Turkey, Sicily, Italy, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$3,177
Oceanview
$3,565
Balcony
$5,719
Suite
-
From
US$3,177
Save 72
Per Person
View Trip
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