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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 451 unique cruise itineraries from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise in the Mediterranean with 543 departures starting between May 2024 and April 2027.
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451 Cruises (543 Cruise Departures)
11 Day Art De Vivre Experience with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 22 July 2025
Countries Visited: Spain, France, Monaco, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,238
SUITE
$14,198
Save 7,572
From 13,238
View Trip
8 Day A Journey From Civitavecchia To Barcelona with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 September 2025
Countries Visited: Italy, Sicily, Tunisia, Sardinia (+1 more), Spain
Unique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 5,846
View Trip
13 Day Barcelona to Rome with Silversea
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 May 2025
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,315
From 18,315
View Trip
11 Day Tyrrhenian Treasures & Malta with Seabourn
Cruise

11 Days (10 Nights) Monte Carlo to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departures: Apr 2025 to Sep 2025
Countries Visited: Monaco, Italy, Sicily, Malta (+3 more), Corsica, France, Spain
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$8,929
SUITE
$15,913
From 8,929
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Moon
Departure: 01 October 2024
Countries Visited: France, Italy, Monaco, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$12,078
BALCONY
$13,860
SUITE
$33,759
From 12,078
View Trip
21 Day Riviera & Mediterranean Magic with Seabourn
Cruise

21 Days (20 Nights) Rome to Monte Carlo
Cruise Line: Seabourn
Ship: Ovation
Departure: 10 August 2025
Countries Visited: Italy, Malta, Tunisia, France (+3 more), Spain, Sardinia, Monaco
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$14,828
SUITE
$28,545
From 14,828
View Trip
8 Day Rome to Monte Carlo with Silversea
Cruise

8 Days (7 Nights) Rome to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 22 July 2025
Countries Visited: Italy, Monaco
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,306
From 9,306
View Trip
31 Day Riviera, Mediterranean & Tyrrhenian Treasures with Seabourn
Cruise

31 Days (30 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 10 August 2025
Countries Visited: Italy, Malta, Tunisia, France (+5 more), Spain, Sardinia, Monaco, Sicily, Corsica
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$22,411
SUITE
$42,860
From 22,411
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 06 October 2025
Countries Visited: Spain, France, Sardinia, Corsica (+1 more), Italy
Unique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$5,504
SUITE
$6,692
From 5,504
View Trip
8 Day Mediterranean Marvels & Matches: Barcelona Open with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Venture
Departure: 13 April 2025
Countries Visited: Italy, France, Spain
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$7,749
SUITE
$18,436
From 7,749
View Trip
8 Day Cruising the Mediterranean: Sicily, Sardinia, and Mallorca - with Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Valletta to Tarragona
Cruise Line: Ponant
Ship: L'Austral
Departure: 03 October 2025
Countries Visited: Malta, Sicily, Sardinia, Spain
Exclusive Savings
INSIDE
-
OCEANVIEW
$6,772
BALCONY
$7,282
SUITE
$10,859
Save 128
From 6,772
View Trip
8 Day France And Italy with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 16 June 2025
Countries Visited: Spain, France, Sardinia, Sicily (+1 more), Italy
INSIDE
$1,338
OCEANVIEW
$1,556
BALCONY
$1,783
SUITE
$3,744
From 1,338
View Trip
31 Day Best Of The Mediterranean with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 05 May 2025
Countries Visited: Spain, France, Monaco, Italy (+6 more), Corsica, Sardinia, Malta, Tunisia, Gibraltar, Morocco
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$25,693
SUITE
-
From 25,693
View Trip
12 Day Antiquity To Anatolia with Oceania Cruises
Cruise

12 Days (11 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 29 October 2025
Countries Visited: Italy, Sicily, Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,924
SUITE
$10,844
Save 2,056
From 6,924
View Trip
10 Day Athens to Athens with Silversea
Cruise

10 Days (9 Nights) Athens to Athens
Cruise Line: Silversea
Ship: Silver Muse
Departure: 08 October 2025
Countries Visited: Greece, Turkey, Cyprus, Israel
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$10,296
SUITE
$15,840
From 10,296
View Trip
11 Day Cradle Of Empires with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 17 October 2024
Countries Visited: Italy, France, Spain, Gibraltar (+1 more), Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,208
SUITE
$13,901
Save 6,462
From 12,208
View Trip
21 Day Tyrrhenian Treasures & Mediterranean Jewels with Seabourn
Cruise

21 Days (20 Nights) Monte Carlo to Monte Carlo
Cruise Line: Seabourn
Ship: Ovation
Departure: 30 August 2025
Countries Visited: Monaco, Italy, Sicily, Malta (+4 more), Corsica, France, Spain, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$16,512
SUITE
$28,882
From 16,512
View Trip
11 Day Riviera & Mediterranean Jewels with Seabourn
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departures: Jul 2024 to Nov 2025
Countries Visited: Italy, Malta, Tunisia, France (+1 more), Spain
The Sail Away EventMore Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$8,424
SUITE
$15,913
From 8,424
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 July 2024
Countries Visited: Italy, France, Spain
INSIDE
$1,486
OCEANVIEW
$1,704
BALCONY
$2,001
SUITE
$4,120
From 1,486
View Trip
12 Day Golden Coasts of Italy and France with Emerald Cruises
New ReleaseCruise

12 Days (11 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 26 May 2026
Countries Visited: France, Monaco, Italy, Corsica (+1 more), Sardinia
Exclusive Deal
INSIDE
-
OCEANVIEW
$11,430
BALCONY
-
SUITE
$15,588
Save 3,115
From 11,430
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 August 2025
Countries Visited: Italy, France, Sardinia, Sicily (+2 more), Corsica, Spain
INSIDE
$2,677
OCEANVIEW
$3,033
BALCONY
$3,568
SUITE
$7,399
From 2,677
View Trip
11 Day Islands of the Mediterranean: Spain to Malta with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 25 April 2026
Countries Visited: Spain, Corsica, Sardinia, Sicily (+1 more), Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,489
BALCONY
-
SUITE
$14,449
Save 2,606
From 10,489
View Trip
11 Day Pearls of Southern Spain & Portugal with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 08 October 2026
Countries Visited: Portugal, Spain, Morocco
Exclusive Deal
INSIDE
-
OCEANVIEW
$11,182
BALCONY
-
SUITE
$15,142
Save 2,613
From 11,182
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 26 July 2025
Countries Visited: Greece, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,579
BALCONY
-
SUITE
$8,890
Save 1,566
From 6,579
View Trip
11 Day Pearls of Southern Spain & Portugal with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 28 September 2026
Countries Visited: Spain, Morocco, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
$11,182
BALCONY
-
SUITE
$15,142
Save 2,613
From 11,182
View Trip
10 Day A Journey From Civitavecchia To Barcelona with Explora Journeys
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 13 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+2 more), Sardinia, Spain
Unique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$7,049
SUITE
$8,593
From 7,049
View Trip
8 Day Riviera Gems & The Calanques with Seabourn
Cruise

8 Days (7 Nights) Barcelona to Monte Carlo
Cruise Line: Seabourn
Ship: Sojourn
Departures: Oct 2024 to Apr 2025
Countries Visited: Spain, France, Sardinia, Italy (+1 more), Monaco
The Sail Away EventMore Moments On Us Offer
INSIDE
-
OCEANVIEW
$5,055
BALCONY
$6,144
SUITE
$12,040
From 5,055
View Trip
21 Day Tyrrhenian & Mediterranean Overture with Seabourn
Cruise

21 Days (20 Nights) Monte Carlo to Rome
Cruise Line: Seabourn
Ship: Ovation
Departures: Apr 2025 to Jul 2025
Countries Visited: Monaco, Italy, Sicily, Malta (+4 more), Corsica, France, Spain, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$16,091
SUITE
$28,714
From 16,091
View Trip
11 Day Mediterranean Magic with Seabourn
Cruise

11 Days (10 Nights) Barcelona to Monte Carlo
Cruise Line: Seabourn
Ship: Ovation
Departure: 31 August 2024
Countries Visited: Spain, Sardinia, France, Italy (+1 more), Monaco
More Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$11,691
SUITE
$48,519
From 11,691
View Trip
8 Day French & Italian Rivieras with Corsica with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Nice
Cruise Line: Emerald Cruises
Ships: Emerald Sakara
Departures: Aug 2025 to Aug 2026
Countries Visited: Italy, Corsica, France, Monaco
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,579
BALCONY
-
SUITE
$8,833
Save 2,092
From 6,579
View Trip
Results: 181-210 of 451

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