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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 605 unique cruise itineraries with 2 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 652 departures starting between February 2026 and October 2028.
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605 Cruises (652 Cruise Departures)
8 Day Relaxing Rivieras with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 06 August 2027
Visit: Spain, France, Italy, Corsica
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,077
Suite
$4,871
From
US$3,077
Save 3,221
Per Person
View Trip
16 Day Athens to Lisbon with Silversea
Cruise

16 Days (15 Nights) Athens to Lisbon
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 07 November 2026
Visit: Greece, Malta, Sicily, Tunisia, Sardinia, Spain, Portugal
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$7,350
Balcony
$8,120
Suite
$7,700
From
US$7,350
Save 3,150
Per Person
View Trip
11 Day Spain Intensive Cruise: Valencia, Malaga & Seville with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 16 June 2026
Visit: Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$2,884
Oceanview
$3,272
Balcony
$4,465
Suite
$7,879
From
US$2,884
Save 65
Per Person
View Trip
9 Day Catalonia to Andalusia with Emerald Cruises
New ReleaseCruise

9 Days (8 Nights) Barcelona to Malaga
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 23 October 2027
Visit: Spain, Gibraltar, Morocco
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$6,294
Balcony
-
Suite
$8,719
From
US$6,294
Save 8,696
Per Person
View Trip
7 Day Monte Carlo to Barcelona with Silversea
Cruise

7 Days (6 Nights) Monte Carlo to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 19 July 2026
Visit: Monaco, France, Spain
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,900
Suite
$5,480
From
US$3,900
Save 2,600
Per Person
View Trip
8 Day Regal Retreat with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 13 June 2027
Visit: Spain, France, Monaco, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,993
Suite
$6,777
From
US$5,993
Save 11,205
Per Person
View Trip
11 Day Yachting Sicily to Elba via the Amalfi Coast with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Valletta to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 30 June 2027
Visit: Italy, Sicily, Malta
Wave Offer
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$8,207
Balcony
-
Suite
$11,214
From
US$8,207
Save 10,783
Per Person
View Trip
8 Day Mediterranean Holiday with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 06 October 2026
Visit: Spain, France, Italy, Corsica, Sardinia, Sicily
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$2,446
Oceanview
$2,786
Balcony
$3,707
Suite
$4,774
From
US$2,446
Save 2,552
Per Person
View Trip
8 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 November 2027
Visit: Italy, France, Spain
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,380
Suite
$6,680
From
US$4,380
Save 2,920
Per Person
View Trip
7 Day Rome to Monte Carlo with Silversea
Cruise

7 Days (6 Nights) Rome to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 09 August 2026
Visit: Italy, France, Monaco
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,020
Suite
$5,040
From
US$4,020
Save 2,680
Per Person
View Trip
16 Day Italy, France, Malta, Croatia & Montenegro with Seabourn
Cruise

16 Days (15 Nights) Genoa to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 April 2027
Visit: Italy, Corsica, Sardinia, Tunisia (+4 more), Sicily, Malta, Croatia, Montenegro
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,109
Suite
-
From
US$10,109
Save 175
Per Person
View Trip
10 Day Italian Shores and Isle of Beauty with Ponant
Cruise
 (1)

10 Days (9 Nights) Valletta to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 June 2027
Visit: Malta, Sicily, Italy, Corsica, France
Inside
-
Oceanview
$7,090
Balcony
$7,470
Suite
$13,900
From
US$7,090
Per Person
View Trip
11 Day Radiant Rivieras with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 November 2026
Visit: Spain, France, Monaco, Italy
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$3,421
Oceanview
$3,955
Balcony
$3,829
Suite
$5,304
From
US$3,421
Save 3,577
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: Mar 2026 to Aug 2026
Visit: France, Italy, Malta, Sicily
All-Inclusive Fare
Last Minute Fare
Exclusive Savings
Inside
-
Oceanview
$6,150
Balcony
$6,950
Suite
$12,780
From
US$6,150
Save 4,720
Per Person
View Trip
11 Day Renaissance & Rivieras with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 June 2027
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$3,129
Oceanview
$3,371
Balcony
$5,360
Suite
$7,397
From
US$3,129
Save 3,269
Per Person
View Trip
15 Day Mediterranean, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Inside
$2,399
Oceanview
$2,699
Balcony
$2,909
Suite
$6,164
From
US$2,399
Per Person
View Trip
11 Day Italy's Islands, Corsica to Monaco with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Rome to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 06 October 2027
Visit: Italy, Sicily, Malta, Sardinia, Corsica, Monaco, France
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$8,001
Balcony
-
Suite
$11,008
From
US$8,001
Save 10,489
Per Person
View Trip
10 Day Mediterranean Masterpieces with Oceania Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 02 June 2027
Visit: Spain, France, Italy, Corsica, Sardinia, Sicily
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,761
Suite
$6,331
From
US$3,761
Save 3,937
Per Person
View Trip
11 Day Mediterranean Isles with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 November 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$3,128
Oceanview
$3,953
Balcony
$3,750
Suite
$5,302
From
US$3,128
Save 3,270
Per Person
View Trip
8 Day Yachting Gems of the French and Italian Rivieras with Emerald Cruises
New ReleaseCruise

8 Days (7 Nights) Barcelona to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 14 August 2027
Visit: Spain, France, Corsica, Italy
Wave Offer
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$5,652
Balcony
-
Suite
$7,762
From
US$5,652
Save 8,338
Per Person
View Trip
8 Day Cultures & Cuisines with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 15 July 2027
Visit: Spain, Corsica, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,071
Suite
$7,365
From
US$7,071
Save 12,327
Per Person
View Trip
8 Day Iconic Cote D'azur with Regent Seven Seas
Cruise

8 Days (7 Nights) Monte Carlo to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 06 July 2026
Visit: Monaco, Italy, Sardinia, Tunisia, Sicily
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,879
Suite
$7,516
From
US$6,879
Save 11,519
Per Person
View Trip
11 Day Italy & France Spotlight with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 22 May 2026
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$3,323
Oceanview
$3,662
Balcony
-
Suite
-
From
US$3,323
Save 3,475
Per Person
View Trip
15 Day Italy And Adriatic with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Visit: Spain, Italy, Sicily, Greece, Montenegro, Croatia, Malta
Inside
$2,399
Oceanview
$2,659
Balcony
$2,919
Suite
$6,223
From
US$2,399
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Florence & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 May 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Inside
$1,939
Oceanview
$2,229
Balcony
$2,878
Suite
$4,614
From
US$1,939
Per Person
View Trip
8 Day Ancient Sites & Cities with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 November 2026
Visit: Italy, Sicily, Malta, Greece, Turkey
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$1,955
Balcony
$2,822
Suite
$3,894
From
US$1,955
Save 2,643
Per Person
View Trip
8 Day Enchanting Italian Coastlines with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ships: Emerald Sakara
Departures: Jul 2026 to Aug 2027
Visit: Italy, Sardinia, Corsica
Early Payment Discount
Wave Offer
Exclusive Savings
Inside
-
Oceanview
$6,046
Balcony
-
Suite
$6,361
From
US$6,046
Save 21,286
Per Person
View Trip
9 Day Mediterranean Sunrise with Oceania Cruises
Cruise
 (1)

9 Days (8 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 03 March 2027
Visit: Portugal, Spain, France, Italy
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,280
Oceanview
$2,517
Balcony
$3,620
Suite
$5,002
From
US$2,280
Save 2,518
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 13 July 2026
Visit: Italy, France, Corsica, Spain
Inside
$2,279
Oceanview
$2,369
Balcony
$2,799
Suite
$6,230
From
US$2,279
Per Person
View Trip
9 Day Barcelona to Monte Carlo with Silversea
Cruise

9 Days (8 Nights) Barcelona to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 25 July 2026
Visit: Spain, Corsica, France, Monaco
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,800
Suite
$7,000
From
US$4,800
Save 3,200
Per Person
View Trip
Results: 241-270 of 605

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