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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 716 unique cruise itineraries with 1210 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 810 departures starting between March 2026 and November 2028.
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716 Cruises (810 Cruise Departures)
22 Day Ultimate Italy, French Riviera & the Mediterranean Islands with Scenic
New ReleaseCruise

22 Days (21 Nights) Rome to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 27 June 2028
Visit: Italy, Monaco, France, Spain, Corsica, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$63,497
Suite
$73,488
From
US$63,497
Save 1,883
Per Person
View Trip
8 Day Gastronomic Journey Through Iberian Coasts with Ponant
Cruise
 (2)

8 Days (7 Nights) Lisbon to Barcelona
Cruise Line: Ponant
Ship: Le Boreal
Departure: 25 April 2027
Visit: Portugal, Spain
Inside
-
Oceanview
$5,830
Balcony
$6,150
Suite
$11,470
From
US$5,830
Per Person
View Trip
6 Day Palma De Mallorca to Nice with Silversea
Cruise

6 Days (5 Nights) Palma de Mallorca to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: Jun 2026 to Aug 2026
Visit: Spain, France
All-Inclusive Plus Fare
All-Inclusive Fare
Last Minute Fare
Exclusive Savings
Inside
-
Oceanview
$3,050
Balcony
$5,500
Suite
$9,900
From
US$3,050
Save 1,500
Per Person
View Trip
9 Day Riviera Charm Including Monaco Grand Prix with Emerald Cruises
New ReleaseCruise

9 Days (8 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 04 June 2027
Visit: France, Monaco, Italy
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,867
From
US$11,867
Save 918
Per Person
View Trip
10 Day Spain's Southern Coast & Riviera Gems with Seabourn
Cruise
 (1)

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 01 November 2026
Visit: Italy, Corsica, Sardinia, Spain, Portugal
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
$7,514
Balcony
$9,327
Suite
$15,290
From
US$7,514
Save 135
Per Person
View Trip
9 Day A Celebration of Art: The French & Italian Rivieras and Corsica with Ponant
Cruise

9 Days (8 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 10 July 2026
Visit: France, Corsica, Italy
Inside
-
Oceanview
-
Balcony
$9,110
Suite
$16,030
From
US$9,110
Per Person
View Trip
13 Day Warm Winter Wonderland with Oceania Cruises
Cruise

13 Days (12 Nights) Athens to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 08 December 2027
Visit: Greece, Cyprus, Turkey, Malta, Sicily, Sardinia, Spain
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,009
Suite
$6,919
From
US$4,009
Save 4,189
Per Person
View Trip
10 Day Epicurean Odyssey with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 27 September 2027
Visit: Spain, France, Monaco, Italy, Corsica, Sardinia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,499
Oceanview
$2,693
Balcony
$4,196
Suite
$6,136
From
US$2,499
Save 2,499
Per Person
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Kaia
Departures: May 2027 to Oct 2027
Visit: Italy, Sicily, Malta
Preferred Plus Fare + Air Credit
Select Fare
Exclusive Savings
Inside
-
Oceanview
$8,175
Balcony
-
Suite
$10,870
From
US$8,175
Save 702
Per Person
View Trip
12 Day Epicurean Spotlight On Wine with Regent Seven Seas
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 18 September 2026
Visit: Spain, Monaco, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,938
Suite
$15,408
From
US$13,938
Save 14,460
Per Person
View Trip
12 Day Lisbon to Barcelona with Silversea
Cruise

12 Days (11 Nights) Lisbon to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 24 March 2027
Visit: Portugal, Morocco, Spain, Gibraltar
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,600
Suite
$11,200
From
US$7,600
Save 2,500
Per Person
View Trip
10 Day Mysteries Of History with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 24 May 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,430
Oceanview
$2,600
Balcony
$4,389
Suite
$6,232
From
US$2,430
Save 2,968
Per Person
View Trip
13 Day Barcelona to Lisbon with Silversea
Cruise

13 Days (12 Nights) Barcelona to Lisbon
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 23 April 2027
Visit: Spain, Morocco, Gibraltar, Portugal
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,700
Suite
$17,900
From
US$9,700
Save 2,500
Per Person
View Trip
6 Day Corsica and the French Riviera with Ponant
Cruise
 (1)

6 Days (5 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 20 May 2026
Visit: France, Corsica
Inside
-
Oceanview
-
Balcony
$4,710
Suite
$8,360
From
US$4,710
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 23 July 2027
Visit: Italy, Spain, Sardinia, Corsica
Bonus Onboard Credit
Inside
$1,179
Oceanview
$1,279
Balcony
$1,349
Suite
$2,649
From
US$1,179
Per Person
View Trip
11 Day Mediterranean Isles with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 November 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Your World Inclusions
Exclusive Savings
Inside
$3,710
Oceanview
-
Balcony
$3,454
Suite
$4,643
From
US$3,454
Save 6,644
Per Person
View Trip
13 Day An Extended Journey To Mediterranean Elegance: From F1 Race Weekend To Calming Scenic Shores with Explora Journeys
Cruise

13 Days (12 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 03 June 2026
Visit: Monaco, Italy, Sicily, Malta, Spain
Ocean View in Monaco
3 Day Paddock Club Access
Inside
-
Oceanview
-
Balcony
-
Suite
$21,500
From
US$21,500
Per Person
View Trip
5 Day Break Between Provence and Catalonia with Ponant
Cruise
 (1)

5 Days (4 Nights) Nice to Barcelona
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 08 August 2027
Visit: France, Spain
Inside
-
Oceanview
-
Balcony
$3,050
Suite
$5,650
From
US$3,050
Per Person
View Trip
22 Day French Yacht Harbors, Sardinia & Corsica with Seabourn
Cruise

22 Days (21 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 29 July 2028
Visit: Italy, France, Spain, Corsica (+5 more), Sardinia, Sicily, Malta, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,624
Suite
$22,003
From
US$13,624
Save 235
Per Person
View Trip
10 Day Medieval Mediterranean with Oceania Cruises
Cruise

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 19 February 2028
Visit: Turkey, Greece, Malta, Sicily, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,646
Suite
$5,168
From
US$2,646
Save 2,752
Per Person
View Trip
15 Day Mediterranean And Greece with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 24 September 2027
Visit: Italy, France, Corsica, Spain, Sicily, Greece, Turkey
Bonus Onboard Credit
Inside
$2,229
Oceanview
$2,439
Balcony
$2,659
Suite
$5,698
From
US$2,229
Per Person
View Trip
8 Day A Journey Of Antique Treasures To Sumptuous Catalan with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 July 2026
Visit: Italy, Monaco, France, Spain
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$6,555
From
US$6,555
Per Person
View Trip
15 Day Vibrant Cultural Tapestry with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 26 August 2027
Visit: Portugal, Spain, France, Sardinia, Tunisia, Sicily, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$4,110
Oceanview
$4,498
Balcony
$7,311
Suite
$9,930
From
US$4,110
Save 4,288
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Florence, Nice & Barcelona with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 27 May 2027
Visit: Italy, France, Spain
Azamara Always Included
Inside
$2,099
Oceanview
$2,347
Balcony
$3,084
Suite
$4,917
From
US$2,099
Per Person
View Trip
6 Day A Journey Of Historic Beauty & Coastal Discovery with Explora Journeys
Cruise

6 Days (5 Nights) Cartagena to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 May 2026
Visit: Colombia, France, Monaco, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$3,785
From
US$3,785
Per Person
View Trip
10 Day Toast To Toulon with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 31 August 2027
Visit: Spain, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,406
Suite
$10,798
From
US$10,406
Save 10,792
Per Person
View Trip
8 Day Spain, France & Italy Cruise: Barcelona, Nice & Portovenere with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 02 June 2028
Visit: Spain, France, Italy
Azamara Always Included
Inside
$2,049
Oceanview
$2,277
Balcony
$2,665
Suite
$4,023
From
US$2,049
Per Person
View Trip
9 Day Knights & Sunsets with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 20 November 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,344
Suite
$9,520
From
US$8,344
Save 8,654
Per Person
View Trip
12 Day Picturesque Panoramas with Regent Seven Seas
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 22 August 2027
Visit: Spain, France, Monaco, Italy, Corsica, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,467
Suite
$13,937
From
US$12,467
Save 12,931
Per Person
View Trip
8 Day French & Italian Rivieras with Corsica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Sakara
Departures: Apr 2026 to Aug 2027
Visit: France, Monaco, Italy, Corsica
Preferred Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
$7,294
Balcony
-
Suite
$9,161
From
US$7,294
Save 267
Per Person
View Trip
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