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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 715 unique cruise itineraries with 1209 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 810 departures starting between March 2026 and November 2028.
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715 Cruises (810 Cruise Departures)
8 Day Barcelona to Rome with Silversea
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 07 September 2026
Visit: Spain, Sardinia, Tunisia, Sicily, Italy
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,400
Suite
$10,800
From
US$7,400
Save 1,500
Per Person
View Trip
11 Day Royal Palaces & The Rock with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 07 July 2027
Visit: Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$3,180
Oceanview
$3,374
Balcony
$5,314
Suite
$7,400
From
US$3,180
Save 3,318
Per Person
View Trip
11 Day Riviera Yacht Harbors with Seabourn
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 25 April 2026
Visit: Spain, France, Monaco, Italy
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,447
Suite
$13,447
From
US$13,447
Save 252
Per Person
View Trip
8 Day Spain Intensive: Malaga, Valencia & Barcelona with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Malaga to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 February 2027
Visit: Spain, Morocco
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$1,739
Oceanview
$1,999
Balcony
$2,279
Suite
$3,559
From
US$1,739
Per Person
View Trip
20 Day Discover the Beauty of the Mediterranean with Emerald Cruises
New ReleaseCruise
 (3)

20 Days (19 Nights) Lisbon to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 30 April 2027
Visit: Portugal, Spain, Morocco, Sardinia (+4 more), Corsica, Italy, Sicily, Malta
Exclusive Savings
Inside
-
Oceanview
$19,750
Balcony
-
Suite
-
From
US$19,750
Save 540
Per Person
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 October 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,000
Suite
$12,500
From
US$9,000
Save 2,500
Per Person
View Trip
6 Day Sicilian interlude with Ponant
Cruise
 (2)

6 Days (5 Nights) Palermo to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 June 2027
Visit: Sicily, Italy, Malta
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
9 Day Total Solar Eclipse in the Mediterranean with Ponant
Cruise
 (2)

9 Days (8 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 06 August 2026
Visit: France, Corsica, Spain
Inside
-
Oceanview
-
Balcony
$9,630
Suite
-
From
US$9,630
Per Person
View Trip
18 Day Grand Mediterranean Jewels with Oceania Cruises
Cruise

18 Days (17 Nights) Tarragona to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 October 2026
Visit: Spain, France, Italy, Sicily, Malta, Tunisia, Sardinia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,018
Suite
$12,946
From
US$9,018
Save 9,480
Per Person
View Trip
9 Day Peaceful Islands and Ancient Treasures of the Mediterranean with Ponant
Cruise
 (2)

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 17 August 2027
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$6,510
Suite
$12,100
From
US$6,510
Per Person
View Trip
8 Day Ancient Sites & Cities with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 November 2026
Visit: Italy, Sicily, Malta, Greece, Turkey
Your World Inclusions
Exclusive Savings
Inside
$1,610
Oceanview
$1,715
Balcony
$2,637
Suite
$3,438
From
US$1,610
Save 2,988
Per Person
View Trip
7 Day A Journey Of Sunset Shores & Mediterranean Icons with Explora Journeys
Cruise

7 Days (6 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2027
Visit: Italy, Corsica, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,365
From
US$5,365
Per Person
View Trip
11 Day Charmed Rivieras with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 21 April 2026
Visit: Spain, France, Corsica, Sardinia, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
$3,470
Balcony
-
Suite
-
From
US$3,470
Save 3,628
Per Person
View Trip
8 Day France Cruise: Marseille, Nice & St. Tropez with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Nice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 26 May 2026
Visit: Spain, France
Azamara Always Included
Inside
$1,139
Oceanview
-
Balcony
$2,059
Suite
-
From
US$1,139
Per Person
View Trip
10 Day Lisbon to Civitavecchia (Rome) with Silversea
Cruise

10 Days (9 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 06 September 2027
Visit: Portugal, Spain, France, Italy
All-Inclusive Fare
Inside
-
Oceanview
$8,700
Balcony
$9,200
Suite
$8,900
From
US$8,700
Per Person
View Trip
6 Day From Riviera Glamour to Corsican Charm with Ponant
Cruise
 (2)

6 Days (5 Nights) Barcelona to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 02 May 2027
Visit: Spain, France, Corsica
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,730
From
US$3,940
Per Person
View Trip
9 Day Croatia, Montenegro, Italy & Greece with Seabourn
Cruise

9 Days (8 Nights) Dubrovnik to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 06 August 2027
Visit: Croatia, Montenegro, Italy, Greece
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,353
Suite
$12,754
From
US$8,353
Save 156
Per Person
View Trip
8 Day Authentic Mediterranean Shores with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: Ponant
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2027 to May 2027
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$5,690
Suite
$10,580
From
US$5,690
Per Person
View Trip
8 Day Montenegro, Italy & Greece with Seabourn
Cruise

8 Days (7 Nights) Dubrovnik to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: May 2027 to Oct 2028
Visit: Croatia, Montenegro, Italy, Greece
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,864
Suite
$7,951
From
US$4,864
Save 161
Per Person
View Trip
8 Day Christmas Cruise: Florence, Mahon & Palma with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Visit: Italy, Spain
Azamara Always Included
Inside
$2,049
Oceanview
$2,039
Balcony
$2,326
Suite
$4,237
From
US$2,039
Per Person
View Trip
8 Day European Yearnings with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 02 July 2027
Visit: Italy, Monaco, France, Spain
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,175
Suite
$4,921
From
US$3,175
Save 3,323
Per Person
View Trip
10 Day Monte Carlo to Barcelona with Silversea
Cruise

10 Days (9 Nights) Monte Carlo to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 August 2026
Visit: Monaco, France, Spain
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$4,950
Suite
$7,950
From
US$4,950
Per Person
View Trip
7 Day Corsican shores, Under Sail Aboard Le Ponant with Ponant
Cruise

7 Days (6 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departure: 26 September 2026
Visit: France, Corsica
Inside
-
Oceanview
$12,490
Balcony
$16,020
Suite
$17,190
From
US$12,490
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Florence & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 May 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Inside
$2,119
Oceanview
$2,383
Balcony
$3,150
Suite
$5,080
From
US$2,119
Per Person
View Trip
15 Day Spain & Portugal Cruise: Valencia, Seville & Lisbon with Azamara Cruises
Cruise
 (3)

15 Days (14 Nights) Barcelona to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 11 March 2028
Visit: Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$3,568
Oceanview
$4,179
Balcony
$5,333
Suite
$7,913
From
US$3,568
Save 71
Per Person
View Trip
13 Day Radiant Coasts with Regent Seven Seas
Cruise

13 Days (12 Nights) Athens to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 11 August 2026
Visit: Greece, Malta, Italy, France, Spain, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,919
Suite
$15,997
From
US$14,919
Save 15,479
Per Person
View Trip
8 Day Ionian Exploration with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 October 2027
Visit: Greece, Turkey, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$4,491
From
US$2,599
Save 2,599
Per Person
View Trip
16 Day An Extended Journey Through Mediterranean Grandeur with Explora Journeys
Cruise

16 Days (15 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 29 June 2026
Visit: Italy, Corsica, France, Spain, Tunisia, Malta, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$11,475
From
US$11,475
Per Person
View Trip
11 Day Culinary Wonders with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 August 2027
Visit: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,193
Suite
$12,369
From
US$11,193
Save 11,605
Per Person
View Trip
12 Day Mediterranean Rivieras with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 27 October 2026
Visit: Italy, Corsica, Spain, Morocco, Portugal
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,392
From
US$11,392
Save 1,498
Per Person
View Trip
Results: 301-330 of 715

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