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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 451 unique cruise itineraries from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise in the Mediterranean with 543 departures starting between May 2024 and April 2027.
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451 Cruises (543 Cruise Departures)
11 Day Voyage To The Adriatic with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 22 August 2025
Countries Visited: Italy, Sicily, Malta, Greece (+3 more), Albania, Montenegro, Croatia
Exclusive Deal
INSIDE
$5,042
OCEANVIEW
$5,497
BALCONY
$7,942
SUITE
$10,635
Save 2,038
From 5,042
View Trip
11 Day Italy & Dalmatian Coast with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Riviera
Departure: 17 June 2024
Countries Visited: Italy, Sicily, Malta, Greece (+2 more), Croatia, Montenegro
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$8,358
SUITE
$10,823
Save 2,072
From 8,358
View Trip
11 Day Jewels of the Italian Riviera with Ponant
Cruise
 (1)

11 Days (10 Nights) Nice to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 28 June 2025
Countries Visited: France, Italy, Sicily
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$11,442
SUITE
$20,526
Save 218
From 11,442
View Trip
11 Day Allure Of The Adriatic with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 07 July 2025
Countries Visited: Italy, Sicily, Greece, Albania (+3 more), Montenegro, Croatia, Slovenia
Exclusive Deal
INSIDE
$5,349
OCEANVIEW
$5,804
BALCONY
$8,249
SUITE
$11,091
Save 2,041
From 5,349
View Trip
22 Day France, Italy And Adriatic with Cunard
Cruise

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 September 2025
Countries Visited: Spain, Sardinia, Corsica, Sicily (+5 more), Italy, Greece, Montenegro, Croatia, Malta
INSIDE
$4,145
OCEANVIEW
$4,521
BALCONY
$5,362
SUITE
$11,005
From 4,145
View Trip
15 Day France, Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 16 June 2025
Countries Visited: Spain, France, Sardinia, Sicily (+4 more), Italy, Greece, Montenegro, Croatia
INSIDE
$2,588
OCEANVIEW
$2,855
BALCONY
$3,568
SUITE
$7,043
From 2,588
View Trip
13 Day Best Of The Med Voyage with Azamara Cruises
Cruise

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 13 July 2024
Countries Visited: Spain, France, Monaco, Italy (+3 more), Montenegro, Croatia, Slovenia
Circle Club Voyage
INSIDE
$3,593
OCEANVIEW
$3,197
BALCONY
$4,525
SUITE
$7,361
From 3,197
View Trip
8 Day Rome To Trieste with Cunard
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 May 2024
Countries Visited: Italy, Greece, Montenegro, Croatia
INSIDE
$1,882
OCEANVIEW
$2,229
BALCONY
-
SUITE
$13,366
From 1,882
View Trip
22 Day Italy, Spain And Adriatic with Cunard
Cruise

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Countries Visited: Spain, Sardinia, Sicily, Italy (+4 more), Greece, Montenegro, Croatia, Malta
INSIDE
$4,857
OCEANVIEW
$5,253
BALCONY
$6,095
SUITE
$12,876
From 4,857
View Trip
11 Day Icons Of Greece with Regent Seven Seas
Cruise

11 Days (10 Nights) Athens to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 05 October 2025
Countries Visited: Greece, Albania, Montenegro, Croatia (+2 more), Slovenia, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,168
SUITE
$14,792
Save 6,172
From 13,168
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2026 to Jun 2026
Countries Visited: Spain, France, Italy, Corsica (+4 more), Sicily, Greece, Montenegro, Croatia
INSIDE
$3,867
OCEANVIEW
$4,263
BALCONY
$4,857
SUITE
$10,203
From 3,867
View Trip
22 Day Greece, Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 21 July 2025
Countries Visited: Italy, Greece, Montenegro, Croatia (+4 more), Malta, France, Sardinia, Sicily
INSIDE
$4,105
OCEANVIEW
$4,550
BALCONY
$5,352
SUITE
$11,055
From 4,105
View Trip
22 Day Greece, Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 26 May 2025
Countries Visited: Italy, Greece, Montenegro, Croatia (+3 more), Malta, Corsica, Spain
INSIDE
$4,145
OCEANVIEW
$4,521
BALCONY
$5,174
SUITE
$11,005
From 4,145
View Trip
8 Day Island Hopping Aboard Le Ponant, from Athens to Dubrovnik with Ponant
Cruise

8 Days (7 Nights) Athens to Dubrovnik
Cruise Line: Ponant
Ship: Le Ponant
Departures: Jul 2024 to Jul 2025
Countries Visited: Greece, Montenegro, Croatia
Exclusive Solo OfferNo Single Supplement
INSIDE
-
OCEANVIEW
$16,925
BALCONY
$19,846
SUITE
$21,306
Save 338
From 16,925
View Trip
22 Day Greece, Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 July 2025
Countries Visited: Spain, Corsica, France, Italy (+5 more), Sardinia, Sicily, Greece, Montenegro, Croatia
INSIDE
$3,927
OCEANVIEW
$4,283
BALCONY
$4,996
SUITE
$10,698
From 3,927
View Trip
8 Day Italy And Adriatic with Cunard
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Countries Visited: Italy, Greece, Montenegro, Croatia
INSIDE
$1,783
OCEANVIEW
$1,981
BALCONY
$2,179
SUITE
$4,951
From 1,783
View Trip
15 Day Italy And The Adriatic with Cunard
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Jun 2024 to Aug 2024
Countries Visited: Italy, Greece, Montenegro, Croatia (+1 more), Malta
INSIDE
$2,746
OCEANVIEW
$3,380
BALCONY
$3,677
SUITE
$7,686
From 2,746
View Trip
22 Day Greece, Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 29 June 2026
Countries Visited: Italy, Greece, Montenegro, Croatia (+2 more), Malta, France
INSIDE
$4,758
OCEANVIEW
$5,253
BALCONY
$6,095
SUITE
$12,876
From 4,758
View Trip
15 Day Journey To The Aegean with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 31 July 2024
Countries Visited: Italy, Sicily, Greece, Croatia (+2 more), Montenegro, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,804
SUITE
$12,736
Save 12,446
From 11,804
View Trip
15 Day Spain, Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 June 2026
Countries Visited: Italy, Greece, Montenegro, Croatia (+2 more), Malta, Spain
INSIDE
$3,172
OCEANVIEW
$3,518
BALCONY
$3,964
SUITE
$8,518
From 3,172
View Trip
15 Day Mediterranean Essence with Oceania Cruises
Cruise

15 Days (14 Nights) Barcelona to Valletta
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 02 October 2024
Countries Visited: Spain, France, Corsica, Italy (+5 more), Sicily, Greece, Montenegro, Croatia, Malta
Exclusive DealSingles Special Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$10,025
SUITE
$13,510
Save 2,085
From 10,025
View Trip
12 Day Italy Cruise: Hidden Treasures from Florence to Venice with Abercrombie & Kent
New ReleaseCruise

12 Days (11 Nights) Florence to Venice
Operated By: Abercrombie & Kent
Departures: Sep 2024 to Sep 2025
Trip Styles: Group, Cruise
Countries Visited: Italy, Corsica, Sardinia, Sicily
Exclusive DealExclusive Solo Offer
Save 1,540
From 23,070
View Trip
22 Day Italy, France, Spain And Adriatic with Cunard
Cruise

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Countries Visited: Italy, Greece, Montenegro, Croatia (+4 more), Malta, Spain, Corsica, Sicily
INSIDE
$4,857
OCEANVIEW
$5,253
BALCONY
$6,095
SUITE
$12,876
From 4,857
View Trip
22 Day Italy, Spain And Adriatic with Cunard
Cruise

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 June 2026
Countries Visited: Italy, Greece, Montenegro, Croatia (+3 more), Malta, Spain, France
INSIDE
$4,610
OCEANVIEW
$4,956
BALCONY
$5,748
SUITE
$12,183
From 4,610
View Trip
11 Day Mediterranean Portrait with Oceania Cruises
Cruise

11 Days (10 Nights) Valletta to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 16 October 2024
Countries Visited: Malta, Croatia, Montenegro, Italy (+2 more), Greece, Sicily
Exclusive DealSingles Special Offer
INSIDE
$5,912
OCEANVIEW
-
BALCONY
$7,585
SUITE
$10,129
Save 2,048
From 5,912
View Trip
22 Day Greece, Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 August 2025
Countries Visited: Spain, Malta, Italy, Croatia (+3 more), Montenegro, Greece, France
INSIDE
$4,105
OCEANVIEW
$4,550
BALCONY
$5,352
SUITE
$11,055
From 4,105
View Trip
15 Day Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Countries Visited: Spain, Italy, Sicily, Greece (+3 more), Montenegro, Croatia, Malta
INSIDE
$3,320
OCEANVIEW
$3,667
BALCONY
$4,162
SUITE
$8,914
From 3,320
View Trip
8 Day Central Mediterranean with Cunard
Cruise

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 August 2025
Countries Visited: Spain, Malta, Italy, Croatia
INSIDE
$1,516
OCEANVIEW
$1,694
BALCONY
$1,962
SUITE
$4,189
From 1,516
View Trip
15 Day Italy, Spain And Adriatic with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Countries Visited: Italy, Greece, Montenegro, Croatia (+2 more), Malta, Spain
INSIDE
$3,320
OCEANVIEW
$3,667
BALCONY
$4,162
SUITE
$8,914
From 3,320
View Trip
11 Day Athens to Venice with Silversea
Cruise

11 Days (10 Nights) Athens to Venice
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 27 April 2025
Countries Visited: Greece, Montenegro, Italy, Croatia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$12,870
BALCONY
$14,355
SUITE
$14,256
From 12,870
View Trip
Results: 301-330 of 451

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