Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 715 unique cruise itineraries with 1209 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 810 departures starting between March 2026 and November 2028.
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715 Cruises (810 Cruise Departures)
Cruise
 (1)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Departure: 29 June 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia, Malta, France
Inside
-
Oceanview
-
Balcony
$4,569
Suite
-
From
US$4,569
Per Person
View Trip
New ReleaseCruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Scenic
Departure: 23 September 2026
Visit: Spain, France
Preferred Plus Fare + Air Credit
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,077
Suite
$17,365
From
US$13,077
Save 2,468
Per Person
View Trip
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Departure: 06 October 2026
Visit: Spain, France, Italy, Corsica, Sardinia, Sicily
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,834
Oceanview
$2,980
Balcony
$4,192
Suite
$5,065
From
US$2,834
Save 2,964
Per Person
View Trip
Cruise
 (3)

9 Days (8 Nights) Barcelona to Lisbon
Cruise Line: Azamara Cruises
Departure: 11 December 2027
Visit: Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$1,999
Oceanview
$2,496
Balcony
$3,078
Suite
$4,562
From
US$1,999
Per Person
View Trip
Cruise

11 Days (10 Nights) Nice to Lisbon
Cruise Line: Silversea
Departure: 11 August 2027
Visit: France, Spain, Gibraltar, Portugal
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$6,200
Balcony
$7,400
Suite
$13,000
From
US$6,200
Save 3,500
Per Person
View Trip
New ReleaseCruise

10 Days (9 Nights) Barcelona to Palma de Mallorca
Cruise Line: Emerald Cruises
Departure: 10 September 2026
Visit: Spain, France, Monaco, Corsica, Sardinia
Preferred Plus Fare + Air Credit
Select Fare
Exclusive Savings
Inside
-
Oceanview
$7,105
Balcony
-
Suite
$9,423
From
US$7,105
Save 890
Per Person
View Trip
Cruise

12 Days (11 Nights) Monte Carlo to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 17 September 2026
Visit: Monaco, France, Spain
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$11,300
Suite
$15,800
From
US$11,300
Per Person
View Trip
New ReleaseCruise

9 Days (8 Nights) Barcelona to Malaga
Cruise Line: Emerald Cruises
Departure: 23 October 2027
Visit: Spain, Gibraltar, Morocco
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
$6,487
Balcony
-
Suite
$8,652
From
US$6,487
Save 808
Per Person
View Trip
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Departure: 18 September 2027
Visit: Italy, Monaco, France, Spain
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,146
Suite
$11,772
From
US$8,146
Save 153
Per Person
View Trip
Cruise

10 Days (9 Nights) Lisbon to Nice
Cruise Line: Silversea
Departure: 23 March 2027
Visit: Portugal, Spain, France
All-Inclusive Fare
Inside
-
Oceanview
$8,200
Balcony
$8,900
Suite
$12,100
From
US$8,200
Per Person
View Trip
New ReleaseCruise

11 Days (10 Nights) Valletta to Valletta
Cruise Line: Emerald Cruises
Departure: 20 July 2026
Visit: Malta, Sicily, Tunisia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,183
From
US$11,183
Save 312
Per Person
View Trip
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Departure: 01 November 2026
Visit: Italy, Malta, Tunisia, Sicily, France, Spain
Exclusive Savings
Inside
-
Oceanview
$8,203
Balcony
$9,428
Suite
$10,996
From
US$8,203
Save 8,495
Per Person
View Trip
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 05 October 2026
Visit: Italy, Monaco, France, Spain, Sicily
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$12,825
From
US$12,825
Per Person
View Trip
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Regent Seven Seas
Departure: 28 November 2027
Visit: Spain, France, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,558
Suite
$8,538
From
US$7,558
Save 7,840
Per Person
View Trip
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Jun 2026 to Sep 2026
Visit: Italy, Corsica, France, Spain
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$5,520
From
US$5,520
Per Person
View Trip
Cruise

16 Days (15 Nights) Genoa to Dubrovnik
Cruise Line: Seabourn
Departure: 30 April 2027
Visit: Italy, Corsica, Sardinia, Tunisia (+4 more), Sicily, Malta, Croatia, Montenegro
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,476
Suite
$24,726
From
US$12,476
Save 223
Per Person
View Trip
Cruise

22 Days (21 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Departure: 30 September 2028
Visit: Italy, France, Spain, Sardinia (+6 more), Corsica, Monaco, Sicily, Malta, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,888
Suite
$22,267
From
US$13,888
Save 241
Per Person
View Trip
Cruise

9 Days (8 Nights) Nice to Barcelona
Cruise Line: Ponant
Departure: 03 August 2026
Visit: France, Corsica, Sardinia, Spain
Inside
-
Oceanview
-
Balcony
$8,310
Suite
$15,620
From
US$8,310
Per Person
View Trip
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Departure: 10 April 2026
Visit: Spain, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,689
Suite
$9,032
From
US$8,689
Save 9,009
Per Person
View Trip
Cruise

5 Days (4 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 29 March 2026
Visit: Italy, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$2,415
From
US$2,415
Per Person
View Trip
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 26 December 2027
Visit: Spain, France, Italy, Corsica
Inside
-
Oceanview
-
Balcony
-
Suite
$5,590
From
US$5,590
Per Person
View Trip
Cruise

20 Days (19 Nights) Athens to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 April 2026
Visit: Greece, Sicily, Malta, Tunisia (+5 more), Spain, Morocco, France, Monaco, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$13,235
From
US$13,235
Per Person
View Trip
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Seabourn
Departure: 30 October 2027
Visit: Greece, Malta, Sicily, Sardinia, Spain
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,384
Suite
$10,696
From
US$6,384
Save 115
Per Person
View Trip
Cruise

8 Days (7 Nights) Lisbon to Barcelona
Cruise Line: Regent Seven Seas
Departure: 08 May 2027
Visit: Portugal, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,396
Suite
$9,425
From
US$8,396
Save 8,702
Per Person
View Trip
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Departure: 10 July 2026
Visit: Italy, France, Spain, Gibraltar, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,328
Suite
$15,210
From
US$14,328
Save 14,870
Per Person
View Trip
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Departure: 11 November 2028
Visit: Italy, Monaco, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,866
Suite
$8,667
From
US$4,866
Save 83
Per Person
View Trip
Cruise

29 Days (28 Nights) Rome to Athens
Cruise Line: Seabourn
Departure: 29 July 2028
Visit: Italy, France, Spain, Corsica (+6 more), Sardinia, Sicily, Malta, Montenegro, Croatia, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$18,048
Suite
-
From
US$18,048
Save 311
Per Person
View Trip
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2026
Visit: Monaco, Italy, Sicily, Malta, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,650
From
US$5,650
Per Person
View Trip
Cruise

13 Days (12 Nights) Monte Carlo to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 15 November 2027
Visit: Monaco, France, Spain, Morocco, Portugal
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,500
Suite
$16,900
From
US$7,500
Save 1,500
Per Person
View Trip
Cruise

20 Days (19 Nights) Lisbon to Athens
Cruise Line: Oceania Cruises
Departure: 26 September 2027
Visit: Portugal, Spain, France, Italy (+4 more), Sicily, Tunisia, Malta, Greece
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,446
Suite
$11,744
From
US$8,446
Save 8,852
Per Person
View Trip
Results: 331-360 of 715

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