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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 715 unique cruise itineraries with 1209 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 810 departures starting between March 2026 and November 2028.
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715 Cruises (810 Cruise Departures)
13 Day Lisbon to Civitavecchia (Rome) with Silversea
Cruise

13 Days (12 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 28 September 2027
Visit: Portugal, Spain, Gibraltar, Sardinia, Corsica, Italy
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$8,400
Balcony
$9,500
Suite
$19,500
From
US$8,400
Save 1,500
Per Person
View Trip
11 Day Classic Iberia with Regent Seven Seas
Cruise

11 Days (10 Nights) Athens to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 19 June 2026
Visit: Greece, Malta, Sicily, Tunisia, Spain, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,351
Suite
$13,841
From
US$13,351
Save 13,847
Per Person
View Trip
12 Day Idyllic Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 13 September 2028
Visit: Italy, Sardinia, Corsica, Spain
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,456
Suite
$18,940
From
US$16,456
Save 1,289
Per Person
View Trip
8 Day Pompeii, Sicily, Malta & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Monte Carlo to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 17 June 2028
Visit: Monaco, Italy, Sicily, Malta, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,129
Suite
$8,216
From
US$5,129
Save 90
Per Person
View Trip
15 Day An Extended Journey Through Timeless Coastal Beauty & Cultural Splendour with Explora Journeys
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 31 August 2026
Visit: Spain, Tunisia, Malta, Sicily, Italy, Monaco, France
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$11,400
From
US$11,400
Per Person
View Trip
15 Day Maritime Memories In The Med with Oceania Cruises
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 03 January 2028
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, Morocco
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,398
Suite
$7,696
From
US$4,398
Save 4,600
Per Person
View Trip
10 Day Spellbinding Mediterranean with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 31 October 2027
Visit: Italy, Croatia, Greece, Turkey
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,327
Suite
$10,209
From
US$9,327
Save 9,671
Per Person
View Trip
6 Day A Journey Of Sculpted Isles & Timeless Civilisations with Explora Journeys
Cruise

6 Days (5 Nights) Athens to Valletta
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 April 2026
Visit: Greece, Sicily, Malta
Inside
-
Oceanview
-
Balcony
-
Suite
$3,150
From
US$3,150
Per Person
View Trip
15 Day Italy, Malta, Croatia, Montenegro & Greece with Seabourn
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 08 May 2027
Visit: Italy, Sicily, Malta, Croatia, Montenegro, Greece
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,137
Suite
-
From
US$14,137
Save 262
Per Person
View Trip
11 Day A Journey through Mediterranean Wonders & Ancient Echoes with Explora Journeys
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 March 2027
Visit: Spain, Italy, Malta, Tunisia, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$5,590
From
US$5,590
Per Person
View Trip
11 Day Springtime Sunshine with Oceania Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 05 April 2028
Visit: Spain, Sardinia, Corsica, France, Monaco, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,196
Suite
$6,718
From
US$4,196
Save 4,402
Per Person
View Trip
15 Day An Extended Journey Through Antique Treasures, Mediterranean Flavours & Island Calm with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 07 September 2026
Visit: Italy, Monaco, France, Spain, Sardinia, Corsica
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$11,120
From
US$11,120
Per Person
View Trip
8 Day A Journey of Iconic Islands & Coastal Wonders with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departures: May 2027 to Oct 2027
Visit: Spain, Tunisia, Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$4,450
From
US$4,450
Per Person
View Trip
12 Day Heavenly Islands & Iberian Shores with Ponant
Cruise

12 Days (11 Nights) Barcelona to Porto
Cruise Line: Ponant
Ship: Le Champlain
Departure: 06 May 2026
Visit: Spain, Portugal
Inside
-
Oceanview
-
Balcony
$11,440
Suite
$21,490
From
US$11,440
Per Person
View Trip
8 Day Italy, Malta, Croatia & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 08 May 2027
Visit: Italy, Sicily, Malta, Croatia, Montenegro
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,166
Suite
$15,501
From
US$7,166
Save 133
Per Person
View Trip
8 Day Yacht Harbors Of The Cote D'azur with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Jul 2028 to Sep 2028
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,129
Suite
$8,216
From
US$5,129
Save 90
Per Person
View Trip
6 Day Palma De Mallorca to Nice with Silversea
Cruise

6 Days (5 Nights) Palma de Mallorca to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 27 April 2026
Visit: Spain, France
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
$1,950
Balcony
-
Suite
$6,300
From
US$1,950
Per Person
View Trip
11 Day Islands of the Mediterranean: Spain to Malta with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 25 April 2026
Visit: Spain, Corsica, Sardinia, Sicily, Malta
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,133
From
US$11,133
Save 312
Per Person
View Trip
10 Day Ramblas & The Rivieras with Oceania Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 05 September 2026
Visit: Spain, France, Monaco, Italy (+4 more), Corsica, Sardinia, Sicily, Malta
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,943
Suite
$7,834
From
US$5,943
Save 6,255
Per Person
View Trip
8 Day A Journey Through Istanbul's Cosmopolitan Vibrancy to Rome's Timeless Wonders with Explora Journeys
Cruise

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 12 December 2027
Visit: Turkey, Greece, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$4,420
From
US$4,420
Per Person
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Muse
Departure: 31 July 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
$4,950
Balcony
$5,350
Suite
$8,950
From
US$4,950
Per Person
View Trip
9 Day Spring Awakening on the Mediterranean with Ponant
Cruise

9 Days (8 Nights) Malaga to Barcelona
Cruise Line: Ponant
Ship: L'Austral
Departure: 16 April 2027
Visit: Spain, Algeria, Sardinia
Inside
-
Oceanview
$5,940
Balcony
$6,260
Suite
$11,620
From
US$5,940
Per Person
View Trip
20 Day An Extended Journey From Riviera Icons To Grand Prix Glamour with Explora Journeys
Cruise

20 Days (19 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 27 May 2026
Visit: Spain, France, Sardinia, Italy, Monaco, Sicily, Malta
Ocean View in Monaco
3 Day Paddock Club Access
Inside
-
Oceanview
-
Balcony
-
Suite
$30,500
From
US$30,500
Per Person
View Trip
10 Day Barcelona to Barcelona with Silversea
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Muse
Departure: 29 August 2026
Visit: Spain, France, Monaco
All-Inclusive Fare
Inside
-
Oceanview
$9,300
Balcony
$9,800
Suite
$12,800
From
US$9,300
Per Person
View Trip
12 Day Barcelona to Barcelona with Silversea
Cruise

12 Days (11 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 08 May 2026
Visit: Spain, France, Gibraltar
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$9,400
Suite
-
From
US$9,400
Per Person
View Trip
21 Day Barcelona to Rome with Silversea
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 September 2026
Visit: Spain, France, Monaco, Corsica, Italy, Sicily
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$12,200
Suite
$27,700
From
US$12,200
Per Person
View Trip
15 Day Exploring Pompeii, Sicily, Montenegro & Greece with Seabourn
Cruise

15 Days (14 Nights) Monte Carlo to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 14 October 2028
Visit: Monaco, Italy, Sicily, Malta, Montenegro, Croatia, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,288
Suite
$14,845
From
US$9,288
Save 161
Per Person
View Trip
14 Day An Extended Journey Of Splendid Coastlines & Formula 1 Action with Explora Journeys
Cruise

14 Days (13 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 27 May 2026
Visit: Spain, France, Sardinia, Italy, Monaco
3 Day Paddock Club Access
Inside
-
Oceanview
-
Balcony
-
Suite
$21,500
From
US$21,500
Per Person
View Trip
8 Day French Yacht Harbors, Sardinia & Corsica with Seabourn
Cruise

8 Days (7 Nights) Barcelona to Monte Carlo
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 10 June 2028
Visit: Spain, France, Sardinia, Corsica, Monaco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,129
Suite
$8,216
From
US$5,129
Save 90
Per Person
View Trip
11 Day Spanish Sapphire Shores with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 24 March 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,112
Suite
$11,435
From
US$10,112
Save 10,486
Per Person
View Trip
Results: 391-420 of 715

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