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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 605 unique cruise itineraries with 2 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 652 departures starting between February 2026 and October 2028.
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605 Cruises (652 Cruise Departures)
11 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 22 November 2027
Visit: Italy, Spain, Morocco, Portugal
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$4,880
Balcony
$5,440
Suite
$5,120
From
US$4,880
Save 1,220
Per Person
View Trip
8 Day Enchanting Italian Coastlines with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ships: Emerald Sakara
Departures: Jul 2026 to Aug 2027
Visit: Italy, Sardinia, Corsica
Early Payment Discount
Wave Offer
Exclusive Savings
Inside
-
Oceanview
$6,046
Balcony
-
Suite
$6,361
From
US$6,046
Save 21,286
Per Person
View Trip
12 Day Unhurried Islands of the Mediterranean: Corsica, Sardinia & Sicily with Emerald Cruises
New ReleaseCruise

12 Days (11 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 19 June 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily, Malta
Wave Offer
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$9,126
Balcony
-
Suite
$12,424
From
US$9,126
Save 11,664
Per Person
View Trip
15 Day Grecian Gems, Adriatic & Dalmatian Delights with Seabourn
Cruise
 (1)

15 Days (14 Nights) Dubrovnik to Venice
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 23 August 2026
Visit: Croatia, Italy, Albania, Greece, Slovenia
Explore More
Exclusive Savings
Inside
-
Oceanview
$8,605
Balcony
$12,445
Suite
$18,185
From
US$8,605
Save 149
Per Person
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Visit: Spain, Italy, Sicily, Greece (+4 more), Montenegro, Croatia, Malta, France
Inside
$3,919
Oceanview
$4,299
Balcony
$6,325
Suite
$8,988
From
US$3,919
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 August 2027
Visit: Italy, Corsica, Spain, Malta (+4 more), Montenegro, Croatia, Greece, Sicily
Inside
$2,519
Oceanview
$2,829
Balcony
$3,389
Suite
$8,156
From
US$2,519
Per Person
View Trip
22 Day Italy, Spain, Greece And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Visit: Spain, Corsica, Italy, Malta (+4 more), Montenegro, Croatia, Greece, Sicily
Inside
$3,069
Oceanview
$3,639
Balcony
$4,209
Suite
$8,710
From
US$3,069
Per Person
View Trip
12 Day Italy Cruise: Venice, Sicily & Rome with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 August 2026
Visit: Italy, Sicily, Montenegro
Azamara Always Included
Exclusive Savings
Inside
$3,769
Oceanview
$4,186
Balcony
$4,613
Suite
$7,193
From
US$3,769
Save 90
Per Person
View Trip
15 Day Culinary Coasts with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 15 July 2027
Visit: Spain, Corsica, France, Italy (+4 more), Sardinia, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,800
Suite
$13,996
From
US$13,800
Save 21,298
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 02 July 2027
Visit: Italy, Spain, France, Corsica, Malta, Montenegro, Croatia
Inside
$1,899
Oceanview
$2,159
Balcony
$2,669
Suite
$5,599
From
US$1,899
Per Person
View Trip
15 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia, Spain
Inside
$2,629
Oceanview
$2,929
Balcony
$3,579
Suite
$7,905
From
US$2,629
Per Person
View Trip
22 Day Italy, Greece And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 18 June 2027
Visit: Italy, Malta, Montenegro, Croatia (+5 more), Greece, Sicily, Spain, France, Corsica
Inside
$3,219
Oceanview
$3,819
Balcony
$4,499
Suite
$8,720
From
US$3,219
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 23 July 2027
Visit: Italy, Spain, Sardinia, Corsica, Malta, Croatia
Inside
$1,959
Oceanview
$2,169
Balcony
$2,549
Suite
$5,599
From
US$1,959
Per Person
View Trip
9 Day A Celebration of Art Featuring the 61st Venice Biennale with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 01 July 2026
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$9,870
Suite
$16,550
From
US$9,870
Per Person
View Trip
8 Day Italy, Malta And Adriatic with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 30 July 2027
Visit: Italy, Malta, Croatia
Inside
$1,569
Oceanview
$1,739
Balcony
$2,019
Suite
$4,329
From
US$1,569
Per Person
View Trip
8 Day Mediterranean Wayfarer with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 06 June 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$5,647
From
US$5,647
Save 5,951
Per Person
View Trip
15 Day Italy And Adriatic with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 29 June 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia, Malta
Inside
$2,389
Oceanview
$2,409
Balcony
$3,899
Suite
$7,598
From
US$2,389
Per Person
View Trip
15 Day Italy, Spain And Adriatic with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Visit: Italy, Greece, Montenegro, Croatia, Malta, Spain
Inside
$2,469
Oceanview
$2,619
Balcony
$3,219
Suite
$5,995
From
US$2,469
Per Person
View Trip
15 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 May 2026
Visit: Spain, Corsica, Sicily, Italy, Greece, Montenegro, Croatia
Inside
$2,329
Oceanview
$2,509
Balcony
$4,209
Suite
$15,479
From
US$2,329
Per Person
View Trip
22 Day France, Italy, Croatia & Greece Cruise: Marseille, Florence, Dubrovnik & Athens with Azamara Cruises
Cruise
 (8)

22 Days (21 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 March 2027
Visit: Spain, France, Italy, Sicily (+4 more), Montenegro, Croatia, Slovenia, Greece
Azamara Always Included
Exclusive Savings
Inside
$6,934
Oceanview
$7,836
Balcony
$9,979
Suite
$14,073
From
US$6,934
Save 155
Per Person
View Trip
25 Day Nice to Fusina with Silversea
Cruise

25 Days (24 Nights) Nice to Venice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 13 April 2027
Visit: France, Corsica, Sardinia, Spain (+5 more), Italy, Albania, Montenegro, Croatia, Slovenia
All-Inclusive Fare
Inside
-
Oceanview
$11,000
Balcony
$13,700
Suite
$20,700
From
US$11,000
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Visit: Spain, Corsica, Italy, Malta, Montenegro, Croatia
Inside
$2,069
Oceanview
$2,409
Balcony
$2,799
Suite
$5,916
From
US$2,069
Per Person
View Trip
10 Day Seascapes & Gastronomy with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 06 October 2027
Visit: Italy, Sicily, Malta, Greece, Albania, Montenegro, Croatia
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,499
Oceanview
$2,692
Balcony
$4,195
Suite
$6,135
From
US$2,499
Save 2,499
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Istanbul to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 21 May 2027
Visit: Turkey, Greece, Sicily, Italy (+4 more), Malta, Montenegro, Croatia, Spain
Inside
$3,439
Oceanview
$3,779
Balcony
$4,559
Suite
$8,880
From
US$3,439
Per Person
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 22 June 2026
Visit: Spain, Sardinia, Corsica, Sicily (+5 more), Italy, Greece, Montenegro, Croatia, Malta
Inside
$3,529
Oceanview
-
Balcony
$6,295
Suite
$8,819
From
US$3,529
Per Person
View Trip
12 Day Best Of The Mediterranean Cruise: Monte Carlo, Florence & Dubrovnik with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 29 September 2027
Visit: Spain, France, Monaco, Italy, Montenegro, Croatia
Azamara Always Included
Exclusive Savings
Inside
$3,480
Oceanview
$3,868
Balcony
$4,761
Suite
$7,157
From
US$3,480
Save 79
Per Person
View Trip
8 Day Mediterranean Muse with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 13 August 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,077
Suite
$5,017
From
US$3,077
Save 3,221
Per Person
View Trip
12 Day Italy Intensive Cruise: Florence, Sorrento & Sicily with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 September 2027
Visit: France, Italy, Sicily, Montenegro
Azamara Always Included
Exclusive Savings
Inside
$3,825
Oceanview
$4,271
Balcony
$5,135
Suite
$7,356
From
US$3,825
Save 94
Per Person
View Trip
9 Day Adriatic Jewel with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 11 July 2027
Visit: Italy, Sicily, Montenegro, Croatia, Slovenia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,571
Suite
$8,453
From
US$7,571
Save 12,827
Per Person
View Trip
10 Day Spring In Southern Europe with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 26 April 2027
Visit: Spain, Sardinia, Sicily, Greece, Italy, Croatia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$2,546
Oceanview
$2,789
Balcony
$4,292
Suite
$6,135
From
US$2,546
Save 2,652
Per Person
View Trip
Results: 391-420 of 605

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