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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 451 unique cruise itineraries from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise in the Mediterranean with 543 departures starting between May 2024 and April 2027.
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51 Days
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451 Cruises (543 Cruise Departures)
29 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

29 Days (28 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 15 September 2025
Countries Visited: Italy, Greece, Montenegro, Croatia (+3 more), Malta, Spain, Turkey
INSIDE
$5,741
OCEANVIEW
$6,305
BALCONY
$7,058
SUITE
$15,334
From 5,741
View Trip
16 Day Mediterranean And Greek Islands with Cunard
Cruise

16 Days (15 Nights) London to Istanbul
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 May 2025
Countries Visited: England, Spain, Italy, Greece (+1 more), Turkey
INSIDE
$2,638
OCEANVIEW
$3,014
BALCONY
$3,954
SUITE
$7,053
From 2,638
View Trip
11 Day Ancient jewels of the Mediterranean with Ponant
Cruise

11 Days (10 Nights) Valletta to Antalya
Cruise Line: Ponant
Ship: L'Austral
Departure: 07 May 2025
Countries Visited: Malta, Sicily, Italy, Greece (+1 more), Turkey
Exclusive Savings
INSIDE
-
OCEANVIEW
$11,912
BALCONY
$12,569
SUITE
$23,711
Save 228
From 11,912
View Trip
10 Day Rome to Athens with Silversea
Cruise

10 Days (9 Nights) Rome to Athens
Cruise Line: Silversea
Ship: Silver Muse
Departure: 26 November 2025
Countries Visited: Italy, Sicily, Malta, Greece
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$7,920
BALCONY
$10,296
SUITE
$18,513
From 7,920
View Trip
22 Day Mediterranean And Greek Islands with Cunard
Cruise

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 May 2026
Countries Visited: Spain, Greece, Turkey, France (+1 more), Italy
INSIDE
$4,511
OCEANVIEW
$4,956
BALCONY
$5,798
SUITE
$11,886
From 4,511
View Trip
13 Day Hidden Gems & Turkish Shores with Regent Seven Seas
Cruise

13 Days (12 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 28 September 2024
Countries Visited: Italy, Sicily, Malta, Greece (+2 more), Turkey, Cyprus
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
$7,422
BALCONY
-
SUITE
$10,132
Save 10,198
From 7,422
View Trip
22 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

22 Days (21 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+3 more), France, Greece, Turkey
INSIDE
$5,055
OCEANVIEW
$5,550
BALCONY
$6,441
SUITE
$13,173
From 5,055
View Trip
15 Day Discover Italy, Greece and Turkey with Emerald Cruises
Cruise

15 Days (14 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 19 July 2025
Countries Visited: Greece, Turkey, Italy, Sicily
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$43,134
Save 9,436
From 43,134
View Trip
15 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

15 Days (14 Nights) Rome to Istanbul
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 14 September 2026
Countries Visited: Italy, France, Greece, Turkey
INSIDE
$3,419
OCEANVIEW
$3,865
BALCONY
$4,409
SUITE
$9,409
From 3,419
View Trip
30 Day Mediterranean And Greek Islands with Cunard
Cruise

30 Days (29 Nights) London to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 May 2025
Countries Visited: England, Spain, Italy, Greece (+3 more), Turkey, Montenegro, Croatia
INSIDE
$5,038
OCEANVIEW
$5,553
BALCONY
$6,731
SUITE
$16,463
From 5,038
View Trip
22 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 14 September 2026
Countries Visited: Italy, France, Greece, Turkey
INSIDE
$5,055
OCEANVIEW
$5,550
BALCONY
$6,441
SUITE
$13,173
From 5,055
View Trip
17 Day An Extended Journey Unlocking Mediterranean Myths with Explora Journeys
Cruise

17 Days (16 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 19 June 2024
Countries Visited: Spain, Sicily, Malta, Greece (+1 more), Turkey
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$14,008
SUITE
$16,236
From 14,008
View Trip
15 Day Turquoise Coast, Greek Isles & Ephesus with Seabourn
Cruise

15 Days (14 Nights) Athens to Athens
Cruise Line: Seabourn
Ship: Encore
Departure: 04 May 2025
Countries Visited: Greece, Cyprus, Turkey
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$12,722
SUITE
$21,726
From 12,722
View Trip
22 Day Discover the Wonders of the Mediterranean & Red Sea with Emerald Cruises
New ReleaseCruise

22 Days (21 Nights) Athens to Aqaba
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 21 October 2026
Countries Visited: Greece, Turkey, Cyprus, Israel (+2 more), Egypt, Jordan
Exclusive Deal
INSIDE
-
OCEANVIEW
$22,364
BALCONY
-
SUITE
$29,774
Save 8,226
From 22,364
View Trip
15 Day Istanbul And Greek Islands with Cunard
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 21 September 2026
Countries Visited: Italy, Greece, Turkey
INSIDE
$2,974
OCEANVIEW
$3,469
BALCONY
$3,964
SUITE
$8,419
From 2,974
View Trip
8 Day Greece And Turkey with Cunard
Cruise

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 12 May 2025
Countries Visited: Italy, Greece, Turkey
INSIDE
$1,585
OCEANVIEW
$1,694
BALCONY
$1,981
SUITE
$4,041
From 1,585
View Trip
15 Day Mediterranean And Greek Islands with Cunard
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 May 2026
Countries Visited: Spain, Greece, Turkey
INSIDE
$2,974
OCEANVIEW
$3,469
BALCONY
$3,964
SUITE
$8,419
From 2,974
View Trip
15 Day Ancient Antiquities with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Istanbul
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 02 April 2025
Countries Visited: Spain, Malta, Greece, Egypt (+2 more), Cyprus, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$15,826
SUITE
$17,460
Save 6,944
From 15,826
View Trip
8 Day Spain And Greek Islands with Cunard
Cruise

8 Days (7 Nights) Istanbul to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 06 October 2025
Countries Visited: Turkey, Greece, Spain
INSIDE
$1,585
OCEANVIEW
$1,783
BALCONY
$2,031
SUITE
$4,258
From 1,585
View Trip
15 Day Discover Italy, Greece and Turkey with Emerald Cruises
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 07 June 2025
Countries Visited: Italy, Sicily, Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$16,345
Save 6,165
From 16,345
View Trip
13 Day Italy & Ancient Isles with Oceania Cruises
Cruise

13 Days (12 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 04 October 2025
Countries Visited: Italy, Sicily, Malta, Greece (+1 more), Turkey
Exclusive Deal
INSIDE
$6,964
OCEANVIEW
$8,033
BALCONY
$9,251
SUITE
$12,419
Save 2,056
From 6,964
View Trip
8 Day Mediterranean And Greek Islands with Cunard
Cruise

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 May 2026
Countries Visited: Spain, Greece, Turkey
INSIDE
$1,684
OCEANVIEW
$1,882
BALCONY
$2,130
SUITE
$4,456
From 1,684
View Trip
23 Day Mediterranean And Greek Islands with Cunard
Cruise

23 Days (22 Nights) London to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 May 2025
Countries Visited: England, Spain, Italy, Greece (+1 more), Turkey
INSIDE
$3,769
OCEANVIEW
$4,333
BALCONY
$4,986
SUITE
$10,352
From 3,769
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 21 September 2026
Countries Visited: Italy, Greece, Turkey
INSIDE
$1,684
OCEANVIEW
$1,882
BALCONY
$2,130
SUITE
$4,456
From 1,684
View Trip
8 Day Italian & Aegean Sampler with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 30 April 2026
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$4,644
SUITE
$7,297
Save 2,036
From 4,644
View Trip
23 Day Palazzi To Palm Groves with Oceania Cruises
Cruise
 (1)

23 Days (22 Nights) Valletta to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 25 September 2025
Countries Visited: Malta, Tunisia, Sicily, Italy (+5 more), Corsica, France, Spain, Morocco, Portugal
Exclusive Deal
INSIDE
$9,750
OCEANVIEW
$10,661
BALCONY
$15,551
SUITE
$20,947
Save 2,070
From 9,750
View Trip
21 Day Empires & Explorers with Oceania Cruises
Cruise
 (2)

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 18 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+5 more), Monaco, France, Spain, Portugal, Morocco
Exclusive Deal
INSIDE
$8,578
OCEANVIEW
$9,647
BALCONY
$13,924
SUITE
$18,993
Save 2,062
From 8,578
View Trip
12 Day Barcelona to Malaga with Silversea
Cruise

12 Days (11 Nights) Barcelona to Malaga
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 06 August 2025
Countries Visited: Spain, Gibraltar, Portugal
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$11,781
BALCONY
$13,266
SUITE
$26,532
From 11,781
View Trip
12 Day Italy, Spain And Portugal with Cunard
Cruise

12 Days (11 Nights) Rome to London
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 05 October 2026
Countries Visited: Italy, Spain, Portugal, England
INSIDE
$2,082
OCEANVIEW
$2,428
BALCONY
$2,775
SUITE
$5,943
From 2,082
View Trip
11 Day Mediterranean And Greek Islands with Cunard
Cruise

11 Days (10 Nights) Athens to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 29 September 2026
Countries Visited: Greece, Sardinia, Gibraltar, England
INSIDE
$2,478
OCEANVIEW
$3,270
BALCONY
$4,260
SUITE
$9,210
From 2,478
View Trip
Results: 391-420 of 451

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