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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 604 unique cruise itineraries with 2 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 654 departures starting between February 2026 and October 2028.
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604 Cruises (654 Cruise Departures)
8 Day Heaven On The Med with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 22 July 2027
Visit: Italy, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,973
Suite
$7,316
From
US$6,973
Save 12,225
Per Person
View Trip
13 Day Civitavecchia (Rome) to Fusina (Venice) with Silversea
Cruise

13 Days (12 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 15 September 2027
Visit: Italy, Sicily, Malta, Albania, Montenegro, Croatia
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$7,650
Balcony
$8,730
Suite
$8,100
From
US$7,650
Save 850
Per Person
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 13 July 2026
Visit: Italy, France, Corsica, Spain, Sicily, Greece, Montenegro
Inside
$4,089
Oceanview
$3,779
Balcony
$4,109
Suite
-
From
US$3,779
Per Person
View Trip
12 Day Italy Cruise: Florence, Rome & Sorrento with Azamara Cruises
Cruise
 (4)

12 Days (11 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 13 September 2026
Visit: Spain, France, Monaco, Italy, Sicily, Montenegro, Slovenia
Azamara Always Included
Exclusive Savings
Inside
$4,807
Oceanview
$5,311
Balcony
-
Suite
-
From
US$4,807
Save 122
Per Person
View Trip
12 Day Italy Intensive Cruise: Florence, Sorrento & Sicily with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 September 2027
Visit: France, Italy, Sicily, Montenegro
Azamara Always Included
Exclusive Savings
Inside
$3,825
Oceanview
$4,271
Balcony
$5,135
Suite
$7,356
From
US$3,825
Save 94
Per Person
View Trip
15 Day Italy, Spain And Adriatic with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Visit: Spain, Sardinia, Sicily, Italy, Greece, Montenegro, Croatia
Inside
$2,369
Oceanview
$2,499
Balcony
$4,149
Suite
$6,163
From
US$2,369
Per Person
View Trip
8 Day Croatia, Malta And Montenegro with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 18 June 2027
Visit: Italy, Malta, Montenegro, Croatia
Inside
$1,259
Oceanview
$1,369
Balcony
$1,569
Suite
$4,069
From
US$1,259
Per Person
View Trip
15 Day Italy, Greece And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 10 September 2027
Visit: Spain, Malta, Montenegro, Croatia, Italy, Greece, Sicily
Inside
$1,869
Oceanview
$2,129
Balcony
$2,639
Suite
$5,757
From
US$1,869
Per Person
View Trip
10 Day Romantic Locales & Canals with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 21 June 2027
Visit: Spain, France, Italy, Sicily, Greece, Montenegro, Croatia
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,740
Oceanview
$2,982
Balcony
$4,583
Suite
$6,426
From
US$2,740
Save 2,858
Per Person
View Trip
15 Day Italy, Spain And Adriatic with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Visit: Italy, Greece, Montenegro, Croatia, Malta, Spain
Inside
$2,469
Oceanview
$2,619
Balcony
$3,219
Suite
$5,995
From
US$2,469
Per Person
View Trip
12 Day A Journey Of Creative Spirit & Enchanting Canals with Explora Journeys
Cruise

12 Days (11 Nights) Barcelona to Venice
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 02 April 2026
Visit: Spain, Italy, Malta, Sicily, Greece, Montenegro, Croatia
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$6,935
Suite
$7,835
From
US$6,935
Per Person
View Trip
21 Day Ode On A Grecian Journey with Oceania Cruises
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 17 July 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia, Spain
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,543
Suite
$13,538
From
US$8,543
Save 8,955
Per Person
View Trip
15 Day Mediterranean And Croatia with Cunard
Cruise
 (13)

15 Days (14 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 04 June 2027
Visit: Italy, Croatia, Sicily, Spain, Corsica
Inside
$2,359
Oceanview
$2,679
Balcony
$3,199
Suite
$6,648
From
US$2,359
Per Person
View Trip
18 Day European Artistry with Oceania Cruises
Cruise
 (1)

18 Days (17 Nights) Lisbon to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 24 July 2026
Visit: Portugal, Spain, Gibraltar, Corsica (+6 more), Italy, Sicily, Greece, Montenegro, Croatia, Slovenia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$5,281
Oceanview
-
Balcony
$8,870
Suite
$12,023
From
US$5,281
Save 5,517
Per Person
View Trip
11 Day Ancient Indulgence with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Istanbul to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 28 October 2027
Visit: Turkey, Greece, Montenegro, Croatia, Slovenia, Italy
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$3,036
Oceanview
$3,861
Balcony
$4,588
Suite
$6,528
From
US$3,036
Save 3,162
Per Person
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Visit: Spain, Italy, Sicily, Greece (+4 more), Montenegro, Croatia, Malta, France
Inside
$3,919
Oceanview
$4,299
Balcony
$6,325
Suite
$8,988
From
US$3,919
Per Person
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 July 2026
Visit: Italy, France, Corsica, Spain (+5 more), Sicily, Greece, Montenegro, Croatia, Malta
Inside
$3,429
Oceanview
$3,749
Balcony
$4,439
Suite
$16,007
From
US$3,429
Per Person
View Trip
12 Day Best Of The Mediterranean Cruise: Monte Carlo, Amalfi & Venice with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 24 April 2027
Visit: Spain, France, Monaco, Italy, Montenegro, Croatia, Slovenia
Azamara Always Included
Exclusive Savings
Inside
$3,327
Oceanview
$3,860
Balcony
$4,908
Suite
$7,517
From
US$3,327
Save 72
Per Person
View Trip
8 Day Adriatic & Ionian Artistry with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 12 May 2026
Visit: Italy, Sicily, Greece, Albania, Croatia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
$4,579
Balcony
$3,609
Suite
$4,870
From
US$3,609
Save 3,789
Per Person
View Trip
10 Day Spring In Southern Europe with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 26 April 2027
Visit: Spain, Sardinia, Sicily, Greece, Italy, Croatia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$2,546
Oceanview
$2,789
Balcony
$4,292
Suite
$6,135
From
US$2,546
Save 2,652
Per Person
View Trip
15 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia, Spain
Inside
$2,629
Oceanview
$2,929
Balcony
$3,579
Suite
$7,905
From
US$2,629
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 10 September 2027
Visit: Spain, Malta, Montenegro, Croatia (+5 more), Italy, Greece, Sicily, France, Corsica
Inside
$2,749
Oceanview
$3,129
Balcony
$3,889
Suite
-
From
US$2,749
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 28 May 2027
Visit: Italy, Malta, Montenegro, Croatia, Sicily, Spain, Corsica
Inside
$3,599
Oceanview
$3,969
Balcony
$4,729
Suite
$9,819
From
US$3,599
Per Person
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 May 2026
Visit: Spain, France, Italy, Corsica (+4 more), Sicily, Greece, Montenegro, Croatia
Inside
-
Oceanview
$3,659
Balcony
$4,449
Suite
$10,393
From
US$3,659
Per Person
View Trip
8 Day Viva Italia with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 23 April 2027
Visit: Italy, Sicily, Montenegro, Croatia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,416
Suite
$4,677
From
US$3,416
Save 3,582
Per Person
View Trip
25 Day Nice to Fusina with Silversea
Cruise

25 Days (24 Nights) Nice to Venice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 13 April 2027
Visit: France, Corsica, Sardinia, Spain (+5 more), Italy, Albania, Montenegro, Croatia, Slovenia
All-Inclusive Fare
Inside
-
Oceanview
$11,000
Balcony
$13,700
Suite
$20,700
From
US$11,000
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 23 July 2027
Visit: Italy, Spain, Sardinia, Corsica, Malta, Croatia
Inside
$1,959
Oceanview
$2,169
Balcony
$2,549
Suite
$5,599
From
US$1,959
Per Person
View Trip
22 Day Italy, Greece And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 18 June 2027
Visit: Italy, Malta, Montenegro, Croatia (+5 more), Greece, Sicily, Spain, France, Corsica
Inside
$3,219
Oceanview
$3,819
Balcony
$4,499
Suite
$8,720
From
US$3,219
Per Person
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 May 2026
Visit: Spain, Corsica, Sicily, Italy (+4 more), Greece, Montenegro, Croatia, Malta
Inside
$4,129
Oceanview
-
Balcony
-
Suite
-
From
US$4,129
Per Person
View Trip
8 Day Malta, Croatia And Montenegro with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2027 to Sep 2027
Visit: Spain, Malta, Montenegro, Croatia, Italy
Inside
$949
Oceanview
$1,049
Balcony
$1,199
Suite
$2,979
From
US$949
Per Person
View Trip
Results: 451-480 of 604

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