Home > Cruises > Europe Cruises > Mediterranean Cruises > Luxury Cruises

Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 715 unique cruise itineraries with 1209 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 810 departures starting between March 2026 and November 2028.
Filter Results
Departures
Show More...
Duration
5 Days
50 Days
Start & End Cities
Ship Size
Cruise Lines
Show More...
Price
$1,000pp
$139,998pp
Countries
Show More...
Filter Results
715 Cruises (810 Cruise Departures)
10 Day Lisbon to Civitavecchia (Rome) with Silversea
Cruise

10 Days (9 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 06 September 2027
Visit: Portugal, Spain, France, Italy
All-Inclusive Fare
Inside
-
Oceanview
$8,700
Balcony
$9,200
Suite
$8,900
From
US$8,700
Per Person
View Trip
8 Day A Journey Of Cultural Discovery & Enchanting Coastlines with Explora Journeys
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 07 June 2027
Visit: Monaco, Italy, Corsica, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,365
From
US$5,365
Per Person
View Trip
22 Day Mediterranean Mosaic: Croatia, Italy, France & Spain with Seabourn
Cruise

22 Days (21 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy (+5 more), Monaco, France, Spain, Corsica, Sardinia
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$20,232
Suite
-
From
US$20,232
Save 367
Per Person
View Trip
15 Day Pharaohs & Empires with Regent Seven Seas
Cruise

15 Days (14 Nights) Istanbul to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 15 January 2027
Visit: Turkey, Greece, Cyprus, Egypt
Exclusive Savings
Inside
-
Oceanview
$9,635
Balcony
$12,085
Suite
$13,065
From
US$9,635
Save 9,963
Per Person
View Trip
10 Day From the Iberian Shores to the Italian Coast with Ponant
Cruise

10 Days (9 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 04 April 2027
Visit: Spain, Sicily, Italy, Malta
Inside
-
Oceanview
-
Balcony
$7,320
Suite
$13,610
From
US$7,320
Per Person
View Trip
5 Day A Journey Of Cultural Marvels & Natural Beauty with Explora Journeys
Cruise

5 Days (4 Nights) Barcelona to Valletta
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 02 April 2026
Visit: Spain, Italy, Malta
Inside
-
Oceanview
-
Balcony
-
Suite
$2,510
From
US$2,510
Per Person
View Trip
10 Day Caesars & Conquistadors with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 15 June 2027
Visit: Italy, Monaco, Spain, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,293
Suite
$6,669
From
US$4,293
Save 4,505
Per Person
View Trip
9 Day Mediterranean Islands with Seabourn
Cruise

9 Days (8 Nights) Rome to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,050
Suite
$11,578
From
US$8,050
Save 149
Per Person
View Trip
13 Day Iberian & Italian Autumn with Oceania Cruises
Cruise

13 Days (12 Nights) Lisbon to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 25 September 2027
Visit: Portugal, Spain, France, Italy, Sicily, Greece
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,953
Suite
$9,105
From
US$5,953
Save 6,245
Per Person
View Trip
10 Day Under The Tuscan Sunset with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 17 June 2027
Visit: Spain, Corsica, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,287
Suite
$11,483
From
US$11,287
Save 11,711
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: Apr 2026 to Aug 2026
Visit: France, Italy, Malta, Sicily
All-Inclusive Fare
Last Minute Fare
Inside
-
Oceanview
$6,750
Balcony
$7,250
Suite
$16,000
From
US$6,750
Per Person
View Trip
10 Day Pasta To Paella with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 April 2028
Visit: Italy, Sardinia, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,613
Suite
$6,135
From
US$3,613
Save 3,785
Per Person
View Trip
7 Day A Journey Of Sunset Shores & Mediterranean Icons with Explora Journeys
Cruise

7 Days (6 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2027
Visit: Italy, Corsica, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,365
From
US$5,365
Per Person
View Trip
15 Day An Extended Journey Of Sunlit Discovery & Timeless Wonder with Explora Journeys
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 28 September 2026
Visit: Spain, Tunisia, Malta, Sicily, Italy, Monaco, France
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$12,150
From
US$12,150
Per Person
View Trip
22 Day French Yacht Harbors, Sardinia & Corsica with Seabourn
Cruise

22 Days (21 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 September 2028
Visit: Italy, France, Spain, Sardinia (+6 more), Corsica, Monaco, Sicily, Malta, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,888
Suite
$22,267
From
US$13,888
Save 241
Per Person
View Trip
8 Day Monaco, Italy, France & Spain with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 18 September 2027
Visit: Italy, Monaco, France, Spain
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,146
Suite
$11,772
From
US$8,146
Save 153
Per Person
View Trip
8 Day Monte Carlo to Monte Carlo with Silversea
Cruise

8 Days (7 Nights) Monte Carlo to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 14 August 2027
Visit: Monaco, Italy, Sardinia, Corsica, France
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,100
Suite
$8,100
From
US$5,100
Save 1,500
Per Person
View Trip
9 Day Barcelona to Barcelona with Silversea
Cruise

9 Days (8 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 24 April 2027
Visit: Spain
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$8,000
Suite
$12,200
From
US$8,000
Per Person
View Trip
11 Day Pearls of Southern Spain & Portugal with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 08 October 2026
Visit: Portugal, Spain, Morocco
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,471
From
US$11,471
Save 874
Per Person
View Trip
8 Day Under Sail from Puglia to Sicily with Ponant
Cruise

8 Days (7 Nights) Dubrovnik to Palermo
Cruise Line: Ponant
Ship: Le Ponant
Departure: 17 August 2027
Visit: Croatia, Italy, Sicily
Inside
-
Oceanview
$10,700
Balcony
$17,240
Suite
$19,210
From
US$10,700
Per Person
View Trip
8 Day A Journey Of Mediterranean Wonders From Ancient Secrets To Modern Buzzing Vibes with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 05 October 2026
Visit: Italy, Monaco, France, Spain
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$5,935
From
US$5,935
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 13 April 2027
Visit: France, Corsica, Sardinia, Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$8,300
Balcony
$9,900
Suite
$12,800
From
US$8,300
Save 1,500
Per Person
View Trip
8 Day The French Riviera Under Le Ponant’s Sails with Ponant
Cruise

8 Days (7 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departures: May 2026 to May 2027
Visit: France, Italy
Inside
-
Oceanview
$10,020
Balcony
$16,130
Suite
$17,960
From
US$10,020
Per Person
View Trip
15 Day An Extended Journey From Cultural Gems To Riviera Magic & Balmy Beaches with Explora Journeys
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 03 August 2026
Visit: Spain, Tunisia, Malta, Sicily, Italy, Monaco, France
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$11,135
From
US$11,135
Per Person
View Trip
10 Day Latin Languages Of Love with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 27 March 2028
Visit: Italy, Sicily, Sardinia, Monaco, France, Spain
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,515
Suite
$6,037
From
US$3,515
Save 3,683
Per Person
View Trip
21 Day Discover the Yachting Treasures of the Mediterranean with Emerald Cruises
New ReleaseCruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Visit: Spain, Morocco, Corsica, Sardinia, Sicily, Malta
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$22,115
From
US$22,115
Save 625
Per Person
View Trip
10 Day Iconic Art & Architecture with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 January 2028
Visit: Italy, Sardinia, Spain, Tunisia, Sicily, Malta
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,175
Suite
$4,970
From
US$3,175
Save 3,323
Per Person
View Trip
11 Day Italian Celebration with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 May 2027
Visit: Spain, France, Monaco, Italy, Sicily, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,564
Suite
$13,740
From
US$12,564
Save 13,034
Per Person
View Trip
9 Day Barcelona to Civitavecchia (Rome) with Silversea
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 21 May 2027
Visit: Spain, Sardinia, Sicily, Malta, Italy
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,900
Suite
$11,000
From
US$6,900
Save 2,500
Per Person
View Trip
8 Day Italy, Malta, Croatia & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 08 May 2027
Visit: Italy, Sicily, Malta, Croatia, Montenegro
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,166
Suite
$15,501
From
US$7,166
Save 133
Per Person
View Trip
Results: 451-480 of 715

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Luxury Cruises Short Cruise Breaks

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations