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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 604 unique cruise itineraries with 2 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 654 departures starting between February 2026 and October 2028.
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46 Days
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604 Cruises (654 Cruise Departures)
15 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 22 June 2026
Visit: Spain, Sardinia, Corsica, Sicily (+4 more), Italy, Greece, Montenegro, Croatia
Inside
$2,399
Oceanview
$2,689
Balcony
$3,959
Suite
$6,113
From
US$2,399
Per Person
View Trip
14 Day Isles In Autumn with Regent Seven Seas
Cruise

14 Days (13 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 29 September 2026
Visit: Italy, Tunisia, Malta, Croatia, Montenegro, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,541
Suite
$12,962
From
US$11,541
Save 17,157
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 02 July 2027
Visit: Italy, Spain, France, Corsica (+5 more), Malta, Montenegro, Croatia, Greece, Sicily
Inside
$2,809
Oceanview
$3,199
Balcony
$3,769
Suite
$8,255
From
US$2,809
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 03 September 2027
Visit: Italy, Corsica, Spain, Malta (+4 more), Montenegro, Croatia, Greece, Sicily
Inside
$2,699
Oceanview
$3,089
Balcony
$3,649
Suite
$8,413
From
US$2,699
Per Person
View Trip
8 Day Italy And Adriatic with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Visit: Spain, Italy, Sicily, Greece, Montenegro
Inside
$1,229
Oceanview
$1,379
Balcony
$1,529
Suite
$3,459
From
US$1,229
Per Person
View Trip
15 Day Grecian Gems, Adriatic & Dalmatian Delights with Seabourn
Cruise
 (1)

15 Days (14 Nights) Dubrovnik to Venice
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 23 August 2026
Visit: Croatia, Italy, Albania, Greece, Slovenia
Explore More
Exclusive Savings
Inside
-
Oceanview
$8,605
Balcony
$11,687
Suite
$18,185
From
US$8,605
Save 149
Per Person
View Trip
10 Day Seascapes & Gastronomy with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 06 October 2027
Visit: Italy, Sicily, Malta, Greece, Albania, Montenegro, Croatia
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,499
Oceanview
$2,692
Balcony
$4,195
Suite
$6,135
From
US$2,499
Save 2,499
Per Person
View Trip
8 Day Malta, Croatia And Montenegro with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: May 2027 to Jul 2027
Visit: Italy, Malta, Montenegro, Croatia
Inside
$1,039
Oceanview
$1,139
Balcony
$1,289
Suite
$2,969
From
US$1,039
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Istanbul to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 21 May 2027
Visit: Turkey, Greece, Sicily, Italy (+4 more), Malta, Montenegro, Croatia, Spain
Inside
$3,439
Oceanview
$3,779
Balcony
$4,559
Suite
$8,880
From
US$3,439
Per Person
View Trip
29 Day Mediterranean, Adriatic, Greece And Turkey with Cunard
Cruise
 (13)

29 Days (28 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 May 2027
Visit: Spain, Sicily, Greece, Turkey (+4 more), Italy, Malta, Montenegro, Croatia
Inside
$4,729
Oceanview
$5,179
Balcony
$5,589
Suite
$11,784
From
US$4,729
Per Person
View Trip
8 Day Mystical Italy & Croatia with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 June 2027
Visit: Italy, Sicily, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,189
Suite
$7,169
From
US$6,189
Save 11,409
Per Person
View Trip
19 Day Italia In Full with Regent Seven Seas
Cruise

19 Days (18 Nights) Barcelona to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 May 2027
Visit: Spain, France, Monaco, Italy (+5 more), Sicily, Sardinia, Montenegro, Croatia, Slovenia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,982
Suite
$16,207
From
US$14,982
Save 23,516
Per Person
View Trip
14 Day Eternal Mediterranean with Oceania Cruises
Cruise

14 Days (13 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 02 June 2027
Visit: Greece, Italy, Croatia, Slovenia, Malta, Sicily
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,145
Suite
$9,055
From
US$6,145
Save 6,453
Per Person
View Trip
8 Day Croatian Culture & Cuisine with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 09 September 2027
Visit: Italy, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,679
Suite
$7,267
From
US$6,679
Save 11,919
Per Person
View Trip
8 Day Croatia, Malta & Italy with Seabourn
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 02 October 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,118
Suite
$8,758
From
US$5,118
Save 91
Per Person
View Trip
8 Day Mediterranean Wayfarer with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 06 June 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$5,647
From
US$5,647
Save 5,951
Per Person
View Trip
10 Day Journey Back In Time with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 12 August 2027
Visit: Italy, Malta, Greece, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,564
Suite
$8,348
From
US$7,564
Save 12,834
Per Person
View Trip
22 Day Mediterranean Mosaic: Italy, France, Spain & Malta with Seabourn
Cruise

22 Days (21 Nights) Rome to Venice
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 18 September 2027
Visit: Italy, Monaco, France, Spain (+6 more), Corsica, Sardinia, Sicily, Malta, Montenegro, Croatia
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,199
Suite
$23,362
From
US$14,199
Save 250
Per Person
View Trip
9 Day Adriatic Jewel with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 11 July 2027
Visit: Italy, Sicily, Montenegro, Croatia, Slovenia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,571
Suite
$8,453
From
US$7,571
Save 12,827
Per Person
View Trip
22 Day Mediterranean Mosaic: Spain, France, Italy & Greece with Seabourn
Cruise

22 Days (21 Nights) Barcelona to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 25 September 2027
Visit: Spain, France, Corsica, Sardinia (+7 more), Italy, Sicily, Malta, Montenegro, Croatia, Slovenia, Greece
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,615
Suite
$22,778
From
US$13,615
Save 239
Per Person
View Trip
9 Day Centuries Of Art with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 02 September 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,386
Suite
$7,660
From
US$6,386
Save 11,612
Per Person
View Trip
15 Day Dalmatian Gems, Malta, Italy & Greece with Seabourn
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 02 October 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia, Slovenia, Greece
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,938
Suite
$15,019
From
US$8,938
Save 156
Per Person
View Trip
19 Day Greece, Adriatic, and Western Mediterranean with Cunard
Cruise

19 Days (18 Nights) London to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 11 May 2026
Visit: England, Spain, Sicily, Greece, Croatia, Sardinia, Gibraltar
Inside
$2,829
Oceanview
$4,129
Balcony
$4,979
Suite
$11,481
From
US$2,829
Per Person
View Trip
9 Day Greece, Italy, Montenegro, Croatia & Slovenia with Seabourn
Cruise

9 Days (8 Nights) Athens to Venice
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 05 June 2027
Visit: Greece, Montenegro, Croatia, Slovenia, Italy
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,663
Suite
$8,928
From
US$5,663
Save 99
Per Person
View Trip
9 Day Dalmatian Rhapsody with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 25 May 2027
Visit: Italy, Sicily, Montenegro, Croatia, Slovenia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,484
Suite
$7,366
From
US$6,484
Save 11,714
Per Person
View Trip
13 Day Southern Europe Sojourn with Oceania Cruises
Cruise

13 Days (12 Nights) Barcelona to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 25 June 2026
Visit: Spain, France, Monaco, Corsica (+5 more), Italy, Sicily, Greece, Montenegro, Croatia
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,268
Suite
$8,233
From
US$6,268
Save 8,030
Per Person
View Trip
8 Day Civitavecchia (Rome) to Fusina (Venice) with Silversea
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 August 2027
Visit: Italy, Croatia, Slovenia
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,180
Suite
$8,920
From
US$5,180
Save 2,220
Per Person
View Trip
11 Day Rome to Venice with Silversea
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 03 February 2026
Visit: Italy, Croatia
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
$3,950
Balcony
$4,950
Suite
$9,520
From
US$3,950
Per Person
View Trip
10 Day In Bloom Around The Boot with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 14 May 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,292
Suite
$6,038
From
US$4,292
Save 4,506
Per Person
View Trip
11 Day Rome to Venice with Silversea
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 08 October 2026
Visit: Italy, Sicily, Malta, Montenegro, Croatia
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$7,830
Balcony
$8,370
Suite
$8,100
From
US$7,830
Save 870
Per Person
View Trip
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