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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
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780 Cruises (900 Cruise Departures)
23 Day Riviera Icons, Wild British Isles & Irish Shores with Seabourn
Cruise

23 Days (22 Nights) Genoa to Belfast
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 23 May 2028
Visit: Italy, France, Spain, Morocco (+5 more), Portugal, England, Wales, Ireland, Northern Ireland
Inside
-
Oceanview
-
Balcony
$17,998
Suite
$25,648
From
US$17,998
Per Person
View Trip
22 Day French Yacht Harbors, Sardinia & Corsica with Seabourn
Cruise

22 Days (21 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 03 June 2028
Visit: Italy, France, Spain, Sardinia (+6 more), Corsica, Monaco, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$15,479
Suite
$24,029
From
US$15,479
Per Person
View Trip
15 Day Mediterranean Classics with Oceania Cruises
Cruise

15 Days (14 Nights) Istanbul to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 17 October 2026
Visit: Turkey, Greece, Croatia, Montenegro (+4 more), Sicily, Italy, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,749
Suite
$10,665
From
US$7,749
Save 7,749
Per Person
View Trip
18 Day An Extended Journey Of Italian Grandeur, Catalan Style & North African Artistry with Explora Journeys
Cruise

18 Days (17 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 04 August 2028
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain, Tunisia
Inside
-
Oceanview
-
Balcony
-
Suite
$10,570
From
US$10,570
Per Person
View Trip
8 Day Under Sail from Sicily to the Riviera with Ponant
Cruise

8 Days (7 Nights) Palermo to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departure: 24 August 2027
Visit: Sicily, Italy, France
Inside
-
Oceanview
$12,790
Balcony
$19,470
Suite
$40,250
From
US$12,790
Per Person
View Trip
38 Day Mediterranean Exploration & Evening At Ephesus with Seabourn
Cruise

38 Days (37 Nights) Lisbon to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 06 April 2028
Visit: Portugal, Spain, Morocco, France (+9 more), Corsica, Sardinia, Italy, Sicily, Malta, Montenegro, Croatia, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$26,369
Suite
-
From
US$26,369
Per Person
View Trip
10 Day Spanish Shores & Beyond with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Barcelona to Palma de Mallorca
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 10 September 2026
Visit: Spain, France, Monaco, Corsica, Sardinia
Inside
-
Oceanview
$7,995
Balcony
-
Suite
$10,650
From
US$7,995
Per Person
View Trip
8 Day The French Riviera Under Le Ponant’s Sails with Ponant
Cruise

8 Days (7 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departures: May 2027 to May 2027
Visit: France, Italy
Inside
-
Oceanview
$10,020
Balcony
$16,130
Suite
$17,960
From
US$10,020
Per Person
View Trip
7 Day Corsican shores, Under Sail Aboard Le Ponant with Ponant
Cruise

7 Days (6 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departure: 26 September 2026
Visit: France, Corsica
Inside
-
Oceanview
$12,490
Balcony
$16,020
Suite
$17,190
From
US$12,490
Per Person
View Trip
18 Day Discover the Ancient Treasures of the Mediterranean & Red Sea with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Cairo to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 07 April 2027
Visit: Egypt, Jordan, Israel, Cyprus, Turkey, Greece
Inside
-
Oceanview
-
Balcony
-
Suite
$21,975
From
US$21,975
Per Person
View Trip
9 Day Barcelona to Monte Carlo with Silversea
Cruise

9 Days (8 Nights) Barcelona to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 25 July 2026
Visit: Spain, Corsica, France, Monaco
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$5,250
Suite
$9,100
From
US$5,250
Per Person
View Trip
11 Day French Riviera, Corsica and Monaco Grand Prix with Scenic
New ReleaseCruise

11 Days (10 Nights) Nice to Rome
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 30 May 2027
Visit: France, Corsica, Italy, Monaco
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,130
Suite
$18,015
From
US$11,130
Save 2,765
Per Person
View Trip
8 Day Riviera Reverie with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 30 September 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,099
Suite
$10,749
From
US$10,099
Save 10,099
Per Person
View Trip
11 Day Barcelona to Rome with Silversea
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 28 September 2026
Visit: Spain, France, Monaco, Italy
Last Minute Fare
Inside
-
Oceanview
$4,950
Balcony
$5,950
Suite
$5,850
From
US$4,950
Per Person
View Trip
11 Day Barcelona to Barcelona with Silversea
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 02 May 2027
Visit: Spain, France
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,200
Suite
$10,300
From
US$7,200
Save 1,500
Per Person
View Trip
22 Day Mediterranean Isle Exploration & Evening At Ephesus with Seabourn
Cruise

22 Days (21 Nights) Monte Carlo to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 17 June 2028
Visit: Monaco, Italy, Sicily, Malta (+4 more), Montenegro, Croatia, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$14,129
Suite
$22,679
From
US$14,129
Per Person
View Trip
15 Day Exploring French Yacht Harbors & Mediterranean Isles with Seabourn
Cruise

15 Days (14 Nights) Barcelona to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 07 October 2028
Visit: Spain, France, Sardinia, Corsica (+6 more), Monaco, Italy, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$9,449
Suite
$15,119
From
US$9,449
Per Person
View Trip
12 Day Idyllic Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 07 July 2028
Visit: Spain, Corsica, Italy, Sardinia
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,424
Suite
$17,985
From
US$15,424
Save 2,321
Per Person
View Trip
13 Day A Grand Journey Through Catalan Shores to Saudi Arabian Mystique with Explora Journeys
Cruise

13 Days (12 Nights) Barcelona to Jeddah
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 09 January 2028
Visit: Spain, Italy, Sicily, Egypt, Jordan, Saudi Arabia
Inside
-
Oceanview
-
Balcony
-
Suite
$7,345
From
US$7,345
Per Person
View Trip
29 Day Exploring Spain, Greek Isles & Evening At Ephesus with Seabourn
Cruise

29 Days (28 Nights) Barcelona to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Spain, France, Corsica, Sardinia (+7 more), Italy, Sicily, Malta, Montenegro, Croatia, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$18,089
Suite
$35,639
From
US$18,089
Per Person
View Trip
8 Day A Journey Through Italy's Rich Heritage to Catalan Elegance with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 19 December 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,160
From
US$5,160
Per Person
View Trip
8 Day Relaxation & Romance with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 01 April 2028
Visit: Spain, France, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,749
Suite
$5,299
From
US$3,749
Save 3,749
Per Person
View Trip
11 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 May 2027
Visit: Italy, France, Corsica, Monaco, Spain
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$10,400
Suite
$14,900
From
US$10,400
Per Person
View Trip
8 Day French & Italian Rivieras with Corsica with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 10 July 2027
Visit: Italy, Corsica, Monaco, France
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$5,475
Balcony
-
Suite
$7,428
From
US$5,475
Save 1,620
Per Person
View Trip
22 Day Exploring Montenegro, Italy, Greece, Malta & Sicily with Seabourn
Cruise

22 Days (21 Nights) Athens to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 09 September 2028
Visit: Greece, Italy, Montenegro, Croatia, Slovenia, Malta, Sicily
Inside
-
Oceanview
-
Balcony
$15,749
Suite
$24,839
From
US$15,749
Per Person
View Trip
22 Day French Yacht Harbors, Sardinia & Corsica with Seabourn
Cruise

22 Days (21 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 29 July 2028
Visit: Italy, France, Spain, Corsica (+5 more), Sardinia, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$13,859
Suite
$23,219
From
US$13,859
Per Person
View Trip
8 Day A Journey Of Cultural Discovery & Enchanting Coastlines with Explora Journeys
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 07 June 2027
Visit: Monaco, Italy, Corsica, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,650
From
US$5,650
Per Person
View Trip
8 Day Monaco, Italy, France & Spain with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 18 September 2027
Visit: Italy, Monaco, France, Spain
Inside
-
Oceanview
-
Balcony
$7,054
Suite
$10,454
From
US$7,054
Per Person
View Trip
8 Day Yacht Harbors Of The Cote D'azur with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Jul 2028 to Sep 2028
Visit: Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$5,219
Suite
$8,369
From
US$5,219
Per Person
View Trip
8 Day Mediterranean shores with Ponant
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Ponant
Ship: L'Austral
Departure: 24 April 2027
Visit: Spain, France, Corsica, Sardinia
Inside
-
Oceanview
$5,200
Balcony
$5,480
Suite
$10,170
From
US$5,200
Per Person
View Trip
Results: 481-510 of 780

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