Home > Cruises > Europe Cruises > Mediterranean Cruises > Luxury Cruises

Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 604 unique cruise itineraries with 2 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 654 departures starting between February 2026 and October 2028.
Filter Results
Departures
Show More...
Duration
6 Days
46 Days
Start & End Cities
Ship Size
Cruise Lines
Show More...
Price
$900pp
$102,850pp
Countries
Show More...
Filter Results
604 Cruises (654 Cruise Departures)
13 Day Italian & Adriatic Icons: Rome to Dubrovnik with Emerald Cruises
New ReleaseCruise

13 Days (12 Nights) Rome to Dubrovnik
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departures: May 2027 to Sep 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Wave Offer
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$9,470
Balcony
-
Suite
$13,253
From
US$9,470
Save 12,520
Per Person
View Trip
15 Day Spain, France, Italy, Croatia & Malta with Seabourn
Cruise

15 Days (14 Nights) Barcelona to Venice
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 25 September 2027
Visit: Spain, France, Corsica, Sardinia (+5 more), Italy, Sicily, Malta, Montenegro, Croatia
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,355
Suite
-
From
US$9,355
Save 164
Per Person
View Trip
11 Day Rome to Venice with Silversea
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 23 June 2026
Visit: Italy, Sicily, Malta, Montenegro, Croatia
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$6,580
Balcony
$7,420
Suite
$10,740
From
US$6,580
Save 2,820
Per Person
View Trip
8 Day Magical Mediterranean with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 11 June 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,835
Suite
$4,920
From
US$2,835
Save 2,963
Per Person
View Trip
31 Day Solar Eclipse: Spain, France, Italy & Greece with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 15 July 2027
Visit: Spain, France, Monaco, Italy (+8 more), Corsica, Sardinia, Sicily, Malta, Albania, Croatia, Montenegro, Greece
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$25,295
Suite
$38,290
From
US$25,295
Save 459
Per Person
View Trip
10 Day Circle Italy with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 16 October 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,711
Suite
$8,054
From
US$7,711
Save 12,987
Per Person
View Trip
13 Day Ancient Wonders - Athens to Aqaba via the Suez Canal with Emerald Cruises
New ReleaseCruise

13 Days (12 Nights) Athens to Aqaba
Cruise Line: Emerald Cruises
Ship: Emerald Raiya
Departure: 30 October 2027
Visit: Greece, Turkey, Cyprus, Israel, Egypt, Jordan
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$10,465
Balcony
-
Suite
$14,248
From
US$10,465
Save 13,025
Per Person
View Trip
16 Day A Journey Of Ancient Legends & Breathtaking Innovation with Explora Journeys
Cruise
 (1)

16 Days (15 Nights) Athens to Dubai
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 November 2026
Visit: Greece, Egypt, Saudi Arabia, Oman, United Arab Emirates
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$9,145
Suite
$10,345
From
US$9,145
Per Person
View Trip
12 Day A Grand Journey Of Maritime Majesty & Middle Eastern Soul with Explora Journeys
Cruise

12 Days (11 Nights) Barcelona to Jeddah
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 November 2027
Visit: Spain, Malta, Greece, Cyprus, Egypt, Saudi Arabia
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$5,375
Suite
$6,060
From
US$5,375
Per Person
View Trip
22 Day Path Of The Great Empires with Regent Seven Seas
Cruise

22 Days (21 Nights) Athens to Doha
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 20 October 2027
Visit: Greece, Israel, Egypt, Jordan (+4 more), Saudi Arabia, Oman, United Arab Emirates, Qatar
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,639
Suite
$15,726
From
US$12,639
Save 22,059
Per Person
View Trip
11 Day Antiquities & Ancients with Regent Seven Seas
Cruise

11 Days (10 Nights) Venice to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 21 August 2027
Visit: Italy, Greece, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,236
Suite
$9,726
From
US$9,236
Save 15,562
Per Person
View Trip
24 Day Mediterranean Constellation with Oceania Cruises
Cruise
 (1)

24 Days (23 Nights) Lisbon to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 24 June 2026
Visit: Portugal, Spain, France, Italy (+5 more), Greece, Turkey, Tunisia, Sicily, Monaco
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$7,730
Oceanview
$8,069
Balcony
$11,998
Suite
$16,314
From
US$7,730
Save 8,068
Per Person
View Trip
10 Day Trojan Trek Revisited with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 July 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$2,837
Oceanview
$3,080
Balcony
$4,680
Suite
$6,523
From
US$2,837
Save 2,961
Per Person
View Trip
10 Day Italy & Greece Cruise: Amalfi, Crete & Santorini with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 August 2027
Visit: Italy, Sicily, Greece, Turkey
Azamara Always Included
Exclusive Savings
Inside
$2,894
Oceanview
$3,272
Balcony
$3,990
Suite
$5,775
From
US$2,894
Save 65
Per Person
View Trip
24 Day Mediterranean Cruise: Italy, Greece & France with Azamara Cruises
Cruise
 (3)

24 Days (23 Nights) Nice to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 28 April 2026
Visit: France, Italy, Sardinia, Tunisia (+5 more), Malta, Sicily, Greece, Turkey, Spain
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,974
Suite
-
From
US$11,974
Save 315
Per Person
View Trip
26 Day Greece, Italy & France Cruise: Alexandria, Athens & Nice with Azamara Cruises
Cruise
 (3)

26 Days (25 Nights) Athens to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 February 2028
Visit: Greece, Egypt, Cyprus, Turkey (+4 more), Sicily, Italy, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$6,898
Oceanview
$8,334
Balcony
$10,303
Suite
$14,920
From
US$6,898
Save 151
Per Person
View Trip
29 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise
 (1)

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy, France, Greece, Turkey
Inside
-
Oceanview
$5,889
Balcony
$9,011
Suite
-
From
US$5,889
Per Person
View Trip
11 Day Italian & Aegean Idyll with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 01 May 2026
Visit: Italy, Sicily, Tunisia, Greece, Turkey
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$3,083
Oceanview
$3,389
Balcony
-
Suite
-
From
US$3,083
Save 3,915
Per Person
View Trip
16 Day Croatia, Montenegro & Ephesus with Seabourn
Cruise

16 Days (15 Nights) Dubrovnik to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 06 August 2027
Visit: Croatia, Montenegro, Italy, Greece, Turkey
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,110
Suite
$17,691
From
US$11,110
Save 194
Per Person
View Trip
15 Day Italy, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 May 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Inside
$2,489
Oceanview
$2,719
Balcony
$2,929
Suite
$6,184
From
US$2,489
Per Person
View Trip
40 Day Athens To Lisbon Grand Voyage with Azamara Cruises
Cruise
 (3)

40 Days (39 Nights) Athens to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 February 2028
Visit: Greece, Egypt, Cyprus, Turkey (+6 more), Sicily, Italy, France, Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$9,800
Oceanview
$11,953
Balcony
$15,057
Suite
$22,041
From
US$9,800
Save 219
Per Person
View Trip
40 Day Venice To Lisbon Grand Voyage with Azamara Cruises
Cruise
 (3)

40 Days (39 Nights) Venice to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 10 November 2027
Visit: Italy, Greece, Cyprus, Turkey (+6 more), Egypt, Sicily, France, Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$9,991
Oceanview
$12,339
Balcony
$15,249
Suite
$22,233
From
US$9,991
Save 208
Per Person
View Trip
22 Day Ephesus, Turkey, Grecian Gems & Dalmatian Delights with Seabourn
Cruise
 (1)

22 Days (21 Nights) Dubrovnik to Athens
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 04 October 2026
Visit: Croatia, Italy, Albania, Greece, Turkey
Explore More
Exclusive Savings
Inside
-
Oceanview
$13,539
Balcony
-
Suite
$33,947
From
US$13,539
Save 230
Per Person
View Trip
14 Day Turkey, Egypt & Italy Cruise: Ephesus, Alexandria & Amalfi Coast with Azamara Cruises
Cruise
 (3)

14 Days (13 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 21 November 2027
Visit: Greece, Turkey, Egypt, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$3,368
Oceanview
$4,153
Balcony
$5,181
Suite
$7,509
From
US$3,368
Save 71
Per Person
View Trip
10 Day Civitavecchia (Rome) to Athens (Piraeus) with Silversea
Cruise
 (1)

10 Days (9 Nights) Rome to Athens
Cruise Line: Silversea
Ship: Silver Nova
Departure: 16 April 2027
Visit: Italy, Sicily, Malta, Greece
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,400
Suite
$9,180
From
US$6,400
Save 1,600
Per Person
View Trip
19 Day Greece, Egypt & Italy Cruise: Alexandria, Athens & Amalfi Coast with Azamara Cruises
Cruise
 (3)

19 Days (18 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 February 2028
Visit: Greece, Egypt, Cyprus, Turkey, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$5,358
Oceanview
$6,386
Balcony
$7,812
Suite
$11,139
From
US$5,358
Save 121
Per Person
View Trip
11 Day Rome to Athens with Silversea
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Silversea
Ship: Silver Muse
Departure: 15 March 2026
Visit: Italy, Sicily, Greece, Egypt
All-Inclusive Fare
Inside
-
Oceanview
$8,400
Balcony
-
Suite
$14,880
From
US$8,400
Per Person
View Trip
11 Day Coastal Charisma with Oceania Cruises
Cruise

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 08 March 2028
Visit: Spain, Italy, Sicily, Malta, Greece
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,516
Suite
$6,038
From
US$3,516
Save 3,682
Per Person
View Trip
23 Day Mediterranean Mosaic: Croatia, Greece & Ephesus with Seabourn
Cruise

23 Days (22 Nights) Dubrovnik to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 06 August 2027
Visit: Croatia, Montenegro, Italy, Greece, Turkey
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,456
Suite
$25,452
From
US$15,456
Save 268
Per Person
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 September 2026
Visit: Turkey, Greece, Sicily, Italy
Inside
$1,579
Oceanview
$1,659
Balcony
$1,919
Suite
-
From
US$1,579
Per Person
View Trip
Results: 511-540 of 604

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Food & Wine Cruises Luxury Cruises Short Cruise Breaks

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

About Us | View Your Booking | Operators | Terms & Conditions | Site Map | We're hiring!

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations