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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 679 unique cruise itineraries with 1209 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 773 departures starting between March 2026 and October 2028.
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679 Cruises (773 Cruise Departures)
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 28 May 2027
Visit: Italy, Malta, Montenegro, Croatia, Sicily, Spain, Corsica
Bonus Onboard Credit
Inside
$3,609
Oceanview
$3,959
Balcony
$4,639
Suite
$9,670
From
US$3,609
Per Person
View Trip
22 Day Italy, Greece And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 20 August 2027
Visit: Spain, Malta, Montenegro, Croatia (+4 more), Italy, Greece, Sicily, Corsica
Bonus Onboard Credit
Inside
$2,899
Oceanview
$3,279
Balcony
$3,819
Suite
$8,067
From
US$2,899
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 30 July 2027
Visit: Italy, Malta, Croatia, Greece, Sicily, Corsica, Spain
Inside
$4,259
Oceanview
$4,849
Balcony
$5,809
Suite
$11,997
From
US$4,259
Per Person
View Trip
12 Day Italy Cruise: Florence, Rome & Sorrento with Azamara Cruises
Cruise
 (5)

12 Days (11 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 13 September 2026
Visit: Spain, France, Monaco, Italy, Sicily, Montenegro, Slovenia
Azamara Always Included
Exclusive Savings
Inside
$2,905
Oceanview
$3,352
Balcony
$4,622
Suite
$10,665
From
US$2,905
Save 64
Per Person
View Trip
13 Day Civitavecchia (Rome) to Fusina (Venice) with Silversea
Cruise

13 Days (12 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 15 September 2027
Visit: Italy, Sicily, Malta, Albania, Montenegro, Croatia
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,500
Suite
$18,900
From
US$9,500
Save 1,500
Per Person
View Trip
11 Day Italy, Malta & Montenegro Cruise: Amalfi, Valletta & Kotor with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 09 June 2028
Visit: Italy, Sicily, Malta, Montenegro, Croatia, Slovenia
Azamara Always Included
Exclusive Savings
Inside
$3,033
Oceanview
$3,372
Balcony
$3,887
Suite
$5,885
From
US$3,033
Save 66
Per Person
View Trip
8 Day Adriatic Reflections with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 April 2027
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,785
Oceanview
$3,270
Balcony
$3,609
Suite
$4,919
From
US$2,785
Save 2,913
Per Person
View Trip
8 Day Island Hopping Aboard Le Ponant, from Athens to Dubrovnik with Ponant
Cruise

8 Days (7 Nights) Athens to Dubrovnik
Cruise Line: Ponant
Ship: Le Ponant
Departure: 18 July 2026
Visit: Greece, Montenegro, Croatia
Inside
-
Oceanview
$15,950
Balcony
$18,680
Suite
$37,230
From
US$15,950
Per Person
View Trip
15 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 22 June 2026
Visit: Spain, Sardinia, Corsica, Sicily (+4 more), Italy, Greece, Montenegro, Croatia
Inside
-
Oceanview
$2,699
Balcony
$2,949
Suite
$5,299
From
US$2,699
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 03 September 2027
Visit: Italy, Corsica, Spain, Malta (+4 more), Montenegro, Croatia, Greece, Sicily
Bonus Onboard Credit
Inside
$3,089
Oceanview
$3,479
Balcony
$4,349
Suite
$8,265
From
US$3,089
Per Person
View Trip
18 Day European Artistry with Oceania Cruises
Cruise
 (1)

18 Days (17 Nights) Lisbon to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 24 July 2026
Visit: Portugal, Spain, Gibraltar, Corsica (+6 more), Italy, Sicily, Greece, Montenegro, Croatia, Slovenia
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$5,863
Oceanview
-
Balcony
$8,919
Suite
$11,780
From
US$5,863
Save 6,135
Per Person
View Trip
8 Day Mediterranean Vistas with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 03 August 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia, Slovenia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,492
Oceanview
$2,783
Balcony
$4,238
Suite
$5,014
From
US$2,492
Save 2,606
Per Person
View Trip
8 Day Mount Etna To Lake Bled with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 29 July 2027
Visit: Italy, Sicily, Greece, Croatia, Slovenia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,099
Oceanview
$2,399
Balcony
$3,611
Suite
$5,066
From
US$2,099
Save 2,099
Per Person
View Trip
9 Day A Celebration of Art Featuring the 61st Venice Biennale with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 01 July 2026
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$8,990
Suite
$16,550
From
US$8,990
Per Person
View Trip
10 Day Spring In Southern Europe with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 26 April 2027
Visit: Spain, Sardinia, Sicily, Greece, Italy, Croatia
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,337
Oceanview
$2,499
Balcony
$4,292
Suite
$6,135
From
US$2,337
Save 3,161
Per Person
View Trip
22 Day Italy, France, Spain And Adriatic with Cunard
Cruise
 (1)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Visit: Italy, Sicily, Greece, Montenegro (+4 more), Croatia, Malta, Spain, Corsica
Bonus Onboard Credit
Inside
$3,869
Oceanview
$4,089
Balcony
$6,681
Suite
$9,255
From
US$3,869
Per Person
View Trip
10 Day Seascapes & Gastronomy with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 06 October 2027
Visit: Italy, Sicily, Malta, Greece, Albania, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,595
Oceanview
$2,789
Balcony
$4,195
Suite
$6,135
From
US$2,595
Save 2,703
Per Person
View Trip
9 Day From Malta to the Shores of the Adriatic with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 19 August 2027
Visit: Malta, Sicily, Italy, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$6,510
Suite
$12,090
From
US$6,510
Per Person
View Trip
8 Day Croatia, Malta & Italy with Seabourn
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 02 October 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,656
Suite
$11,772
From
US$7,656
Save 143
Per Person
View Trip
8 Day Mystical Italy & Croatia with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 June 2027
Visit: Italy, Sicily, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,639
Suite
$9,766
From
US$8,639
Save 8,959
Per Person
View Trip
15 Day Spain, France, Italy, Croatia & Malta with Seabourn
Cruise

15 Days (14 Nights) Barcelona to Venice
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 25 September 2027
Visit: Spain, France, Corsica, Sardinia (+5 more), Italy, Sicily, Malta, Montenegro, Croatia
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,647
Suite
-
From
US$13,647
Save 252
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 23 July 2027
Visit: Italy, Spain, Sardinia, Corsica, Malta, Croatia
Inside
$1,959
Oceanview
$2,169
Balcony
$2,549
Suite
$5,599
From
US$1,959
Per Person
View Trip
15 Day Atlantic To Adriatic Sea with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lisbon to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 11 June 2026
Visit: Portugal, Spain, Italy, Sicily, Malta, Montenegro, Croatia
Your World Inclusions
Exclusive Savings
Inside
$3,332
Oceanview
$3,570
Balcony
$5,776
Suite
$7,032
From
US$3,332
Save 6,366
Per Person
View Trip
12 Day Italy Cruise: Venice, Sicily & Rome with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 August 2026
Visit: Italy, Sicily, Montenegro
Azamara Always Included
Exclusive Savings
Inside
$2,925
Oceanview
$3,449
Balcony
$4,166
Suite
$4,991
From
US$2,925
Save 64
Per Person
View Trip
11 Day Italy, Montenegro & Croatia Cruise: Rome, Kotor & Dubrovnik with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 31 October 2027
Visit: Spain, Italy, Sicily, Montenegro, Croatia
Azamara Always Included
Exclusive Savings
Inside
$2,748
Oceanview
$3,340
Balcony
$4,116
Suite
$5,988
From
US$2,748
Save 61
Per Person
View Trip
8 Day Civitavecchia (Rome) to Fusina (Venice) with Silversea
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 August 2027
Visit: Italy, Croatia, Slovenia
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,500
Suite
$9,900
From
US$5,500
Save 2,500
Per Person
View Trip
8 Day Italy, Malta And Adriatic with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 30 July 2027
Visit: Italy, Malta, Croatia
Inside
$1,569
Oceanview
$1,739
Balcony
$2,019
Suite
$4,329
From
US$1,569
Per Person
View Trip
31 Day Solar Eclipse: Spain, France, Italy & Greece with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 15 July 2027
Visit: Spain, France, Monaco, Italy (+8 more), Corsica, Sardinia, Sicily, Malta, Albania, Croatia, Montenegro, Greece
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$31,416
Suite
-
From
US$31,416
Save 583
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Visit: Spain, Corsica, Italy, Malta, Montenegro, Croatia
Bonus Onboard Credit
Inside
$2,049
Oceanview
$2,459
Balcony
$2,779
Suite
$5,817
From
US$2,049
Per Person
View Trip
12 Day Best Of The Mediterranean Cruise: Monte Carlo, Amalfi & Venice with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 24 April 2027
Visit: Spain, France, Monaco, Italy, Montenegro, Croatia, Slovenia
Azamara Always Included
Exclusive Savings
Inside
$3,327
Oceanview
$3,860
Balcony
$4,908
Suite
$7,517
From
US$3,327
Save 72
Per Person
View Trip
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