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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
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780 Cruises (900 Cruise Departures)
9 Day Italy, France & Tunisia with Seabourn
Cruise

9 Days (8 Nights) Genoa to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 April 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily
Inside
-
Oceanview
-
Balcony
$6,119
Suite
$12,834
From
US$6,119
Per Person
View Trip
11 Day Springtime Sunshine with Oceania Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 05 April 2028
Visit: Spain, Sardinia, Corsica, France, Monaco, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,299
Suite
$6,899
From
US$4,299
Save 4,299
Per Person
View Trip
13 Day Iberian & Italian Autumn with Oceania Cruises
Cruise

13 Days (12 Nights) Lisbon to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 25 September 2027
Visit: Portugal, Spain, France, Italy, Sicily, Greece
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,099
Suite
$9,349
From
US$6,099
Save 6,099
Per Person
View Trip
6 Day Nice to Malaga with Silversea
Cruise

6 Days (5 Nights) Nice to Malaga
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 30 August 2026
Visit: France, Spain
Last Minute Fare
Inside
-
Oceanview
$2,950
Balcony
$3,150
Suite
-
From
US$2,950
Per Person
View Trip
13 Day Barcelona to Lisbon with Silversea
Cruise

13 Days (12 Nights) Barcelona to Lisbon
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 23 April 2027
Visit: Spain, Morocco, Gibraltar, Portugal
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,000
Suite
$18,000
From
US$10,000
Save 1,500
Per Person
View Trip
11 Day Iconic Italy & the French Riviera with Scenic
New ReleaseCruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 27 June 2028
Visit: Italy, Monaco, France, Spain
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,998
Suite
$16,326
From
US$13,998
Save 2,247
Per Person
View Trip
8 Day Ancient Cities of the Mediterranean with Ponant
Cruise

8 Days (7 Nights) Athens to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 22 October 2026
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$6,590
Suite
$12,350
From
US$6,590
Per Person
View Trip
10 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 19 September 2027
Visit: Italy, Corsica, France, Spain
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,200
Suite
$11,900
From
US$7,200
Save 2,500
Per Person
View Trip
13 Day Barcelona to Monte Carlo with Silversea
Cruise

13 Days (12 Nights) Barcelona to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 05 September 2026
Visit: Spain, Gibraltar, Monaco
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$6,500
Suite
$13,900
From
US$6,500
Per Person
View Trip
8 Day Relaxing Rivieras with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 06 August 2027
Visit: Spain, France, Italy, Corsica
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,249
Suite
$5,249
From
US$3,249
Save 3,249
Per Person
View Trip
8 Day A Journey Through The Picturesque Mediterranean & Historic Beauty Of The Sparkling Riviera with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Jun 2026 to Aug 2026
Visit: Spain, France, Italy, Sardinia, Corsica
Inside
-
Oceanview
-
Balcony
-
Suite
$5,625
From
US$5,625
Per Person
View Trip
11 Day Athens to Nice with Silversea
Cruise

11 Days (10 Nights) Athens to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 06 May 2028
Visit: Greece, Malta, Italy, France
All-Inclusive Fare
Inside
-
Oceanview
$9,100
Balcony
$10,100
Suite
$28,000
From
US$9,100
Per Person
View Trip
10 Day Islands & Empires with Oceania Cruises
Cruise

10 Days (9 Nights) Barcelona to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 29 October 2027
Visit: Spain, Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,399
Suite
$5,999
From
US$3,399
Save 3,399
Per Person
View Trip
8 Day A Journey Of Island Wonders & Serene Riviera Exploration with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 15 June 2026
Visit: Spain, Sardinia, France, Monaco
Inside
-
Oceanview
-
Balcony
-
Suite
$6,300
From
US$6,300
Per Person
View Trip
8 Day Exploring Italy, Malta & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$4,949
Suite
$8,999
From
US$4,949
Per Person
View Trip
15 Day Mediterranean Odyssey: Spain, Italy and the French Riviera with Scenic
New ReleaseCruise

15 Days (14 Nights) Malaga to Rome
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 21 April 2027
Visit: Spain, France, Monaco, Italy, Corsica
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,144
Suite
$24,248
From
US$15,144
Save 4,151
Per Person
View Trip
22 Day French Yacht Harbors, Montenegro, Italy & Greece with Seabourn
Cruise

22 Days (21 Nights) Barcelona to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 10 June 2028
Visit: Spain, France, Sardinia, Corsica (+7 more), Monaco, Italy, Sicily, Malta, Montenegro, Croatia, Greece
Inside
-
Oceanview
-
Balcony
$14,309
Suite
$22,679
From
US$14,309
Per Person
View Trip
8 Day A Journey Through Ancient Stories, Isles & Eternal Seas with Explora Journeys
Cruise

8 Days (7 Nights) Athens to Venice
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 01 April 2028
Visit: Greece, Croatia, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$4,560
From
US$4,560
Per Person
View Trip
8 Day A Journey Across Mediterranean Masterpieces with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 06 July 2026
Visit: Spain, Tunisia, Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$5,625
From
US$5,625
Per Person
View Trip
8 Day Spain, France & Italy with Seabourn
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Sep 2027 to Aug 2028
Visit: Spain, France, Corsica, Sardinia, Italy
Inside
-
Oceanview
-
Balcony
$5,219
Suite
$8,369
From
US$5,219
Per Person
View Trip
15 Day Culinary Coasts with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 15 July 2027
Visit: Spain, Corsica, France, Italy (+4 more), Sardinia, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,899
Suite
$17,099
From
US$16,899
Save 16,899
Per Person
View Trip
10 Day Ancient Excavation with Oceania Cruises
Cruise

10 Days (9 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 31 March 2028
Visit: Greece, Montenegro, Croatia, Malta, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,899
Suite
$6,299
From
US$3,899
Save 3,899
Per Person
View Trip
11 Day Mediterranean And Greek Islands with Cunard
Cruise

11 Days (10 Nights) Athens to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 29 September 2026
Visit: Greece, Sardinia, Gibraltar, England
Bonus Onboard Credit
Value Fare
Cunard Fare
Inside
$1,699
Oceanview
-
Balcony
$4,969
Suite
$8,239
From
US$1,699
Per Person
View Trip
8 Day Barcelona to Rome with Silversea
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 07 September 2026
Visit: Spain, Sardinia, Tunisia, Sicily, Italy
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$5,250
Balcony
$5,950
Suite
$10,800
From
US$5,250
Per Person
View Trip
29 Day French Yacht Harbors, Pompeii, Sicily & Montenegro with Seabourn
Cruise

29 Days (28 Nights) Dubrovnik to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 23 September 2028
Visit: Croatia, Montenegro, Malta, Sicily (+6 more), Italy, France, Spain, Sardinia, Corsica, Monaco
Inside
-
Oceanview
-
Balcony
$19,259
Suite
$30,779
From
US$19,259
Per Person
View Trip
11 Day Ancient Civilisations, from Italy to Greece with Ponant
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Champlain
Departure: 01 October 2026
Visit: Italy, Sicily, Greece
Inside
-
Oceanview
-
Balcony
$12,004
Suite
$24,415
From
US$12,004
Per Person
View Trip
8 Day A Journey Of Glorious Legacies & Enchanting Discovery with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 04 September 2028
Visit: Italy, Corsica, France, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$4,920
From
US$4,920
Per Person
View Trip
11 Day Barcelona to Barcelona with Silversea
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 October 2026
Visit: Spain, France
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,500
Suite
$10,100
From
US$6,500
Save 4,000
Per Person
View Trip
11 Day Spanish Sapphire Shores with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 24 March 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,399
Suite
$10,599
From
US$9,399
Save 9,399
Per Person
View Trip
15 Day An Extended Journey Into Riviera Romance & Italian Marvels with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 10 August 2026
Visit: Italy, Monaco, France, Spain, Sardinia, Corsica
Inside
-
Oceanview
-
Balcony
-
Suite
$11,135
From
US$11,135
Per Person
View Trip
Results: 541-570 of 780

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