Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 715 unique cruise itineraries with 1209 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 810 departures starting between March 2026 and November 2028.
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715 Cruises (810 Cruise Departures)
Cruise

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Regent Seven Seas
Departure: 15 July 2027
Visit: Spain, Corsica, France, Italy (+4 more), Sardinia, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,034
Suite
$17,230
From
US$17,034
Save 17,664
Per Person
View Trip
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 September 2026
Visit: Italy, Sicily, Montenegro, Croatia
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$11,200
Suite
$20,200
From
US$11,200
Per Person
View Trip
Cruise

13 Days (12 Nights) Nice to Venice
Cruise Line: Silversea
Departure: 12 June 2027
Visit: France, Italy, Albania, Montenegro, Croatia, Slovenia
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$7,800
Balcony
$9,300
Suite
$14,100
From
US$7,800
Save 1,500
Per Person
View Trip
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Departure: 06 June 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,435
Suite
$5,793
From
US$4,435
Save 4,663
Per Person
View Trip
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Departure: 11 July 2027
Visit: Italy, Sicily, Montenegro, Croatia, Slovenia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,629
Suite
$10,511
From
US$9,629
Save 9,969
Per Person
View Trip
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Departure: 17 July 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia, Spain
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,785
Suite
$13,829
From
US$8,785
Save 9,213
Per Person
View Trip
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Departure: 11 June 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,835
Suite
$4,920
From
US$2,835
Save 2,963
Per Person
View Trip
Cruise

22 Days (21 Nights) Barcelona to Athens
Cruise Line: Seabourn
Departure: 25 September 2027
Visit: Spain, France, Corsica, Sardinia (+7 more), Italy, Sicily, Malta, Montenegro, Croatia, Slovenia, Greece
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$20,715
Suite
-
From
US$20,715
Save 384
Per Person
View Trip
New ReleaseCruise

9 Days (8 Nights) Rome to Dubrovnik
Cruise Line: Scenic
Departure: 09 June 2027
Visit: Italy, Greece, Croatia
Preferred Plus Fare + Air Credit
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,044
Suite
$15,988
From
US$12,044
Save 941
Per Person
View Trip
Cruise

8 Days (7 Nights) Valletta to Venice
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 06 April 2026
Visit: Malta, Sicily, Greece, Montenegro, Italy, Croatia
Inside
-
Oceanview
-
Balcony
-
Suite
$6,410
From
US$6,410
Per Person
View Trip
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Regent Seven Seas
Departure: 22 July 2027
Visit: Italy, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,227
Suite
$9,570
From
US$9,227
Save 9,571
Per Person
View Trip
Cruise

15 Days (14 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Departure: 16 September 2028
Visit: Croatia, Slovenia, Montenegro, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,289
Suite
$14,846
From
US$9,289
Save 160
Per Person
View Trip
Cruise

8 Days (7 Nights) Athens to Dubrovnik
Cruise Line: Ponant
Ship: Le Ponant
Departure: 18 July 2026
Visit: Greece, Montenegro, Croatia
Inside
-
Oceanview
$15,950
Balcony
$18,680
Suite
$37,230
From
US$15,950
Per Person
View Trip
Cruise

29 Days (28 Nights) Monte Carlo to Rome
Cruise Line: Seabourn
Departure: 14 October 2028
Visit: Monaco, Italy, Sicily, Malta (+4 more), Montenegro, Croatia, Greece, Slovenia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$18,314
Suite
$29,427
From
US$18,314
Save 315
Per Person
View Trip
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Departure: 20 June 2027
Visit: Italy, Sicily, Croatia, Montenegro, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,793
Suite
$18,165
From
US$16,793
Save 17,405
Per Person
View Trip
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Departure: 25 May 2027
Visit: Italy, Sicily, Montenegro, Croatia, Slovenia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,032
Suite
$9,914
From
US$9,032
Save 9,366
Per Person
View Trip
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Departure: 02 September 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,179
Suite
$10,110
From
US$9,179
Save 9,519
Per Person
View Trip
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Seabourn
Departure: 02 October 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,656
Suite
$11,772
From
US$7,656
Save 143
Per Person
View Trip
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 23 June 2026
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Last Minute Fare
All-Inclusive Plus Fare
All-Inclusive Fare
Inside
-
Oceanview
$6,250
Balcony
$7,050
Suite
$11,900
From
US$6,250
Per Person
View Trip
Cruise

8 Days (7 Nights) Athens to Dubrovnik
Cruise Line: Ponant
Ship: Le Ponant
Departure: 13 July 2027
Visit: Greece, Montenegro, Croatia
Inside
-
Oceanview
$12,050
Balcony
-
Suite
$21,690
From
US$12,050
Per Person
View Trip
New ReleaseCruise

13 Days (12 Nights) Athens to Aqaba
Cruise Line: Emerald Cruises
Departure: 30 October 2027
Visit: Greece, Turkey, Cyprus, Israel, Egypt, Jordan
Preferred Plus Fare + Air Credit
Select Fare
Exclusive Savings
Inside
-
Oceanview
$11,198
Balcony
-
Suite
$14,603
From
US$11,198
Save 1,397
Per Person
View Trip
Cruise
 (1)

16 Days (15 Nights) Athens to Dubai
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 November 2026
Visit: Greece, Egypt, Saudi Arabia, Oman, United Arab Emirates
Inside
-
Oceanview
-
Balcony
-
Suite
$8,185
From
US$8,185
Per Person
View Trip
Cruise

13 Days (12 Nights) Barcelona to Jeddah
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 09 January 2028
Visit: Spain, Italy, Sicily, Egypt, Jordan, Saudi Arabia
Inside
-
Oceanview
-
Balcony
-
Suite
$7,145
From
US$7,145
Per Person
View Trip
Cruise

12 Days (11 Nights) Barcelona to Jeddah
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 November 2027
Visit: Spain, Malta, Greece, Cyprus, Egypt, Saudi Arabia
Inside
-
Oceanview
-
Balcony
-
Suite
$4,740
From
US$4,740
Per Person
View Trip
Cruise

22 Days (21 Nights) Athens to Doha
Cruise Line: Regent Seven Seas
Departure: 20 October 2027
Visit: Greece, Israel, Egypt, Jordan (+4 more), Saudi Arabia, Oman, United Arab Emirates, Qatar
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$18,078
Suite
$19,548
From
US$18,078
Save 18,720
Per Person
View Trip
Cruise
 (8)

10 Days (9 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Departure: 06 August 2027
Visit: Italy, Sicily, Greece, Turkey
Azamara Always Included
Exclusive Savings
Inside
$4,048
Oceanview
$4,582
Balcony
$5,600
Suite
$8,171
From
US$4,048
Save 101
Per Person
View Trip
Cruise
 (1)

17 Days (16 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 April 2026
Visit: Spain, Monaco, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
-
Suite
$10,240
From
US$10,240
Per Person
View Trip
Cruise
 (3)

40 Days (39 Nights) Venice to Lisbon
Cruise Line: Azamara Cruises
Departure: 10 November 2027
Visit: Italy, Greece, Cyprus, Turkey (+6 more), Egypt, Sicily, France, Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$9,991
Oceanview
$12,339
Balcony
$15,249
Suite
$22,233
From
US$9,991
Save 208
Per Person
View Trip
Cruise
 (3)

14 Days (13 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Departure: 21 November 2027
Visit: Greece, Turkey, Egypt, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$3,368
Oceanview
$4,153
Balcony
$5,181
Suite
$7,509
From
US$3,368
Save 71
Per Person
View Trip
Cruise
 (1)

13 Days (12 Nights) Barcelona to Istanbul
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 April 2026
Visit: Spain, Monaco, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
-
Suite
$9,560
From
US$9,560
Per Person
View Trip
Results: 601-630 of 715

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