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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
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780 Cruises (900 Cruise Departures)
15 Day Mediterranean Collage with Oceania Cruises
Cruise

15 Days (14 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 07 August 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,849
Suite
$11,549
From
US$8,849
Save 8,849
Per Person
View Trip
8 Day A Journey Through Riviera Reverie & Centres Of Culture with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 02 October 2028
Visit: Italy, Corsica, France, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$4,255
From
US$4,255
Per Person
View Trip
9 Day Spanish & French Coastal Charm with Seabourn
Cruise

9 Days (8 Nights) Barcelona to Monte Carlo
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 15 July 2027
Visit: Spain, France, Monaco
Inside
-
Oceanview
-
Balcony
$7,309
Suite
$11,899
From
US$7,309
Per Person
View Trip
8 Day Nice to Palma De Mallorca with Silversea
Cruise

8 Days (7 Nights) Nice to Palma de Mallorca
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 01 July 2026
Visit: France, Corsica, Sardinia, Spain
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$4,350
Balcony
-
Suite
$13,600
From
US$4,350
Per Person
View Trip
15 Day An Extended Journey Of Historic Discovery & Bewitching Scenery with Explora Journeys
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Jun 2026 to Aug 2026
Visit: Spain, France, Italy, Sardinia, Corsica
Inside
-
Oceanview
-
Balcony
-
Suite
$10,480
From
US$10,480
Per Person
View Trip
11 Day Celebrate The Year with Regent Seven Seas
Cruise

11 Days (10 Nights) Athens to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 28 December 2028
Visit: Greece, Montenegro, Croatia, Malta, Sicily, Italy, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,199
Suite
$11,749
From
US$10,199
Save 10,199
Per Person
View Trip
8 Day A Journey Through Istanbul's Cosmopolitan Vibrancy to Rome's Timeless Wonders with Explora Journeys
Cruise

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 12 December 2027
Visit: Turkey, Greece, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$4,550
From
US$4,550
Per Person
View Trip
8 Day Florence, Monte Carlo & Southern France with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 November 2028
Visit: Italy, Monaco, France, Spain
Inside
-
Oceanview
-
Balcony
$5,309
Suite
$14,399
From
US$5,309
Per Person
View Trip
29 Day Exploring Italy, Sicily & Dalmatian Coast with Seabourn
Cruise

29 Days (28 Nights) Monte Carlo to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 14 October 2028
Visit: Monaco, Italy, Sicily, Malta (+4 more), Montenegro, Croatia, Greece, Slovenia
Inside
-
Oceanview
-
Balcony
$18,629
Suite
$29,969
From
US$18,629
Per Person
View Trip
7 Day Barcelona to Monte Carlo with Silversea
Cruise

7 Days (6 Nights) Barcelona to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 24 August 2026
Visit: Spain, France, Italy, Corsica, Monaco
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$3,650
Suite
$7,000
From
US$3,650
Per Person
View Trip
11 Day Mediterranean Delights with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Valletta to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 20 July 2026
Visit: Malta, Sicily, Tunisia
Inside
-
Oceanview
-
Balcony
-
Suite
$11,495
From
US$11,495
Per Person
View Trip
8 Day Riviera Radiance with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 22 October 2027
Visit: Italy, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,249
Suite
$4,699
From
US$3,249
Save 3,249
Per Person
View Trip
14 Day Isles In Autumn with Regent Seven Seas
Cruise

14 Days (13 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 29 September 2026
Visit: Italy, Tunisia, Malta, Croatia, Montenegro, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,899
Suite
$15,599
From
US$14,899
Save 14,899
Per Person
View Trip
8 Day Ionian Exploration with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 October 2027
Visit: Greece, Turkey, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,249
Suite
$4,649
From
US$3,249
Save 3,249
Per Person
View Trip
8 Day A Journey From Ancient Wonders To Sparkling Coastal Allure with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Explora Journeys
Ship: Explora VI
Departures: Aug 2028 to Oct 2028
Visit: Italy, Albania, Croatia
Inside
-
Oceanview
-
Balcony
-
Suite
$4,150
From
US$4,150
Per Person
View Trip
35 Day Riviera Icons, Isles Of The United Kingdom & Iceland with Seabourn
Cruise

35 Days (34 Nights) Genoa to Reykjavik
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 23 May 2028
Visit: Italy, France, Spain, Morocco (+8 more), Portugal, England, Wales, Ireland, Northern Ireland, Scotland, Faroe Islands, Iceland
Inside
-
Oceanview
-
Balcony
$29,697
Suite
$40,947
From
US$29,697
Per Person
View Trip
8 Day Civitavecchia (Rome) to Fusina (Venice) with Silversea
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 August 2027
Visit: Italy, Croatia, Slovenia
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,000
Suite
$9,400
From
US$5,000
Save 3,000
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 13 April 2027
Visit: France, Corsica, Sardinia, Spain
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$8,500
Balcony
$10,000
Suite
$12,800
From
US$8,500
Save 1,500
Per Person
View Trip
15 Day Sublime Spain with Regent Seven Seas
Cruise

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 17 October 2027
Visit: Portugal, Spain, Morocco, France, Monaco, Italy, Corsica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,999
Suite
$16,399
From
US$14,999
Save 14,999
Per Person
View Trip
10 Day A Journey Through The Artistic And Historic Spirit Of Mediterranean Coastal Beauty with Explora Journeys
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 12 October 2026
Visit: Spain, France, Italy, Sicily
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$7,245
From
US$7,245
Per Person
View Trip
8 Day Iberian Grandeur with Regent Seven Seas
Cruise

8 Days (7 Nights) Lisbon to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 08 May 2027
Visit: Portugal, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,199
Suite
$9,699
From
US$9,199
Save 9,199
Per Person
View Trip
11 Day Balearic Bliss with Oceania Cruises
Cruise

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 26 September 2027
Visit: Portugal, Spain, France, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,999
Suite
$6,799
From
US$3,999
Save 3,999
Per Person
View Trip
15 Day Exploring Italy, Malta, Montenegro & Greece with Seabourn
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Italy, Sicily, Malta, Montenegro, Croatia, Greece
Inside
-
Oceanview
-
Balcony
$8,909
Suite
$15,389
From
US$8,909
Per Person
View Trip
15 Day Rome to Lisbon with Silversea
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Visit: Italy, Malta, Sicily, Tunisia, Sardinia, Spain, Portugal
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$8,100
Balcony
$8,800
Suite
$16,300
From
US$8,100
Save 4,000
Per Person
View Trip
10 Day Mediterranean Horizons with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 07 October 2027
Visit: Spain, France, Italy, Corsica, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,099
Suite
$12,649
From
US$12,099
Save 12,099
Per Person
View Trip
15 Day An Extended Journey Of Coastal Elegance, Island Spirit And Mediterranean Crossroads with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 02 October 2028
Visit: Italy, Corsica, France, Spain, Tunisia, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$8,085
From
US$8,085
Per Person
View Trip
8 Day Culinary Towns & Villages with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 13 November 2027
Visit: Spain, France, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,999
Suite
$8,699
From
US$7,999
Save 7,999
Per Person
View Trip
8 Day Regal Retreat with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 13 June 2027
Visit: Spain, France, Monaco, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,799
Suite
$9,599
From
US$8,799
Save 8,799
Per Person
View Trip
8 Day Magical Mediterranean with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 11 June 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$5,049
From
US$3,799
Save 3,799
Per Person
View Trip
10 Day Greek & Italian Isles with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 06 October 2027
Visit: Italy, Sicily, Tunisia, Malta, Greece
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,349
Suite
$6,049
From
US$4,349
Save 4,349
Per Person
View Trip
Results: 631-660 of 780

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