Home > Cruises > Europe Cruises > Mediterranean Cruises > Luxury Cruises

Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
Filter Results
Departures
Show More...
Duration
5 Days
63 Days
Start & End Cities
Ship Size
Cruise Lines
Show More...
Price
$600pp
$65,399pp
Countries
Show More...
Filter Results
780 Cruises (900 Cruise Departures)
13 Day Artifacts & Antiquities with Oceania Cruises
Cruise

13 Days (12 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 14 September 2026
Visit: Italy, Sardinia, Sicily, Malta, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,849
Suite
$10,649
From
US$6,849
Save 6,849
Per Person
View Trip
10 Day Circle Italy with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Trieste
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 16 October 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,299
Suite
$11,549
From
US$11,299
Save 11,299
Per Person
View Trip
29 Day Evening At Ephesus & Aegean Yacht Harbors with Seabourn
Cruise

29 Days (28 Nights) Rome to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Italy, Sicily, Malta, Montenegro, Croatia, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$18,089
Suite
$36,449
From
US$18,089
Per Person
View Trip
10 Day In Bloom Around The Boot with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 14 May 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,999
Suite
$6,649
From
US$4,999
Save 4,999
Per Person
View Trip
10 Day A Journey Along Italy’s Riviera & Sapphire Shores with Explora Journeys
Cruise

10 Days (9 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 May 2027
Visit: Italy, France, Sardinia
Inside
-
Oceanview
-
Balcony
-
Suite
$8,450
From
US$8,450
Per Person
View Trip
14 Day Civitavecchia to Barcelona with Silversea
Cruise

14 Days (13 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 12 July 2026
Visit: Italy, France, Monaco, Spain
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$6,800
Suite
$11,800
From
US$6,800
Per Person
View Trip
8 Day Enchanting Italian Coastlines with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ships: Emerald Sakara
Departures: Jul 2026 to Aug 2027
Visit: Italy, Sardinia, Corsica
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$6,847
Balcony
-
Suite
$8,660
From
US$6,847
Save 848
Per Person
View Trip
9 Day Well-being Break in the Mediterranean with Ponant
Cruise

9 Days (8 Nights) Athens to Venice
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 20 July 2027
Visit: Greece, Montenegro, Croatia, Italy
Inside
-
Oceanview
-
Balcony
$6,910
Suite
$12,860
From
US$6,910
Per Person
View Trip
8 Day A Journey Through Cultural Elegance & Timeless Discovery with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 14 August 2028
Visit: Spain, Tunisia, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$4,585
From
US$4,585
Per Person
View Trip
29 Day Hidden Gems Of France, Italy, Croatia & Slovenia with Seabourn
Cruise

29 Days (28 Nights) Barcelona to Venice
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 07 October 2028
Visit: Spain, France, Sardinia, Corsica (+8 more), Monaco, Italy, Sicily, Malta, Montenegro, Croatia, Greece, Slovenia
Inside
-
Oceanview
-
Balcony
$18,809
Suite
$30,149
From
US$18,809
Per Person
View Trip
22 Day Mediterranean Mosaic: Dalmatian Gems, Malta & Ephesus with Seabourn
Cruise

22 Days (21 Nights) Rome to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 02 October 2027
Visit: Italy, Sicily, Malta, Montenegro (+4 more), Croatia, Slovenia, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$19,124
Suite
$26,179
From
US$19,124
Per Person
View Trip
10 Day Fairytales Afloat with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 03 September 2027
Visit: Italy, Sicily, Sardinia, Corsica, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,899
Suite
$6,199
From
US$3,899
Save 3,899
Per Person
View Trip
11 Day Icons Of Antiquity with Regent Seven Seas
Cruise

11 Days (10 Nights) Istanbul to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 30 September 2027
Visit: Turkey, Greece, Cyprus, Israel, Egypt
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,599
Suite
$13,099
From
US$12,599
Save 12,599
Per Person
View Trip
11 Day Nice to Lisbon with Silversea
Cruise

11 Days (10 Nights) Nice to Lisbon
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 30 August 2026
Visit: France, Spain, Gibraltar, Portugal
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$4,850
Balcony
$5,450
Suite
$9,400
From
US$4,850
Per Person
View Trip
15 Day Villas & Venice with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 June 2027
Visit: Italy, Sicily, Croatia, Montenegro, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$18,849
Suite
-
From
US$18,849
Save 18,849
Per Person
View Trip
15 Day An Extended Voyage Of Antique Treasures, Volcanic Views & Tranquil Shores with Explora Journeys
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 06 July 2026
Visit: Spain, Tunisia, Malta, Sicily, Italy, Monaco, France
Inside
-
Oceanview
-
Balcony
-
Suite
$11,250
From
US$11,250
Per Person
View Trip
8 Day Croatian Culture & Cuisine with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 09 September 2027
Visit: Italy, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,399
Suite
$10,999
From
US$10,399
Save 10,399
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: Jul 2026 to Aug 2026
Visit: France, Italy, Malta, Sicily
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$5,950
Balcony
$7,250
Suite
$14,400
From
US$5,950
Per Person
View Trip
18 Day An Extended Journey Through Andalusian Energy, Catalan Creativity & Sicilian Flavours with Explora Journeys
Cruise

18 Days (17 Nights) Lisbon to Venice
Cruise Line: Explora Journeys
Ship: Explora IV
Departure: 14 October 2028
Visit: Portugal, Spain, Morocco, Malta (+4 more), Sicily, Italy, Montenegro, Slovenia
Inside
-
Oceanview
-
Balcony
-
Suite
$10,010
From
US$10,010
Per Person
View Trip
11 Day A Journey Of Inspirational Isles & Spectacular Horizons with Explora Journeys
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 04 August 2028
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$6,580
From
US$6,580
Per Person
View Trip
21 Day An Extended Journey Through Mediterranean Gems & Sun-hazed Gateways with Explora Journeys
Cruise

21 Days (20 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 12 October 2026
Visit: Spain, France, Italy, Sicily, Portugal, Morocco
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$15,130
From
US$15,130
Per Person
View Trip
10 Day Mediterranean Masterpieces with Oceania Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 02 June 2027
Visit: Spain, France, Italy, Corsica, Sardinia, Sicily
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,849
Suite
$7,349
From
US$3,849
Save 3,849
Per Person
View Trip
18 Day Grand Mediterranean Jewels with Oceania Cruises
Cruise

18 Days (17 Nights) Tarragona to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 October 2026
Visit: Spain, France, Italy, Sicily, Malta, Tunisia, Sardinia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,799
Suite
$13,299
From
US$9,799
Save 9,799
Per Person
View Trip
8 Day Mystical Italy & Croatia with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 June 2027
Visit: Italy, Sicily, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,499
Suite
$10,749
From
US$9,499
Save 9,499
Per Person
View Trip
15 Day Spice Trail Sail with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 21 December 2026
Visit: Italy, Sicily, Malta, Egypt, Cyprus, Greece, Turkey
Exclusive Savings
Inside
-
Oceanview
$11,849
Balcony
$14,449
Suite
$14,799
From
US$11,849
Save 11,849
Per Person
View Trip
8 Day Valletta to Lisbon with Silversea
Cruise

8 Days (7 Nights) Valletta to Lisbon
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 October 2026
Visit: Malta, Sicily, Sardinia, Spain, Portugal
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$9,100
Balcony
$9,700
Suite
$16,600
From
US$9,100
Per Person
View Trip
17 Day France, Italy, Tunisia, Monaco & Spain with Seabourn
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2027
Visit: Italy, Corsica, Sardinia, Tunisia (+4 more), Sicily, Monaco, France, Spain
Inside
-
Oceanview
-
Balcony
$12,834
Suite
$19,379
From
US$12,834
Per Person
View Trip
10 Day Seaside Splendor with Oceania Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 17 November 2027
Visit: Spain, Sardinia, Tunisia, Sicily, Malta, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,399
Suite
$5,799
From
US$3,399
Save 3,399
Per Person
View Trip
8 Day A Journey Of Historic Splendour & Stunning Landscapes with Explora Journeys
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2026
Visit: Monaco, Italy, Sicily, Malta, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,950
From
US$5,950
Per Person
View Trip
9 Day Centuries Of Art with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 02 September 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,599
Suite
$10,599
From
US$9,599
Save 9,599
Per Person
View Trip
Results: 691-720 of 780

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Luxury Cruises Short Cruise Breaks

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations