Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 715 unique cruise itineraries with 1209 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 810 departures starting between March 2026 and November 2028.
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715 Cruises (810 Cruise Departures)
Cruise

15 Days (14 Nights) Valletta to Barcelona
Cruise Line: Oceania Cruises
Departure: 22 August 2026
Visit: Malta, Tunisia, Spain, Portugal, Morocco
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,587
Suite
$10,119
From
US$7,587
Save 9,711
Per Person
View Trip
Cruise

8 Days (7 Nights) Barcelona to Lisbon
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 03 August 2026
Visit: Spain, Morocco, Portugal
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$6,345
From
US$6,345
Per Person
View Trip
Cruise
 (3)

36 Days (35 Nights) Rome to Dublin
Cruise Line: Azamara Cruises
Departure: 15 May 2027
Visit: Italy, Monaco, France, Spain (+5 more), Gibraltar, Portugal, England, Scotland, Ireland
Azamara Always Included
Exclusive Savings
Inside
$10,587
Oceanview
$11,770
Balcony
$14,777
Suite
$34,274
From
US$10,587
Save 212
Per Person
View Trip
Cruise
 (3)

46 Days (45 Nights) Rome to London
Cruise Line: Oceania Cruises
Departure: 28 April 2026
Visit: Italy, France, Spain, Morocco (+9 more), Portugal, Guernsey, Holland, Belgium, England, Scotland, Northern Ireland, Ireland, Wales
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$25,435
Suite
-
From
US$25,435
Save 26,763
Per Person
View Trip
Cruise
 (3)

35 Days (34 Nights) Barcelona to Stockholm
Cruise Line: Azamara Cruises
Departure: 16 June 2026
Visit: Spain, Gibraltar, Portugal, France (+11 more), England, Belgium, Holland, Germany, Denmark, Poland, Lithuania, Latvia, Estonia, Finland, Sweden
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$13,009
Balcony
$16,384
Suite
-
From
US$13,009
Save 320
Per Person
View Trip
Cruise
 (3)

22 Days (21 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Departure: 31 October 2027
Visit: Spain, Italy, Sicily, Montenegro (+4 more), Croatia, Greece, Cyprus, Turkey
Azamara Always Included
Exclusive Savings
Inside
$5,801
Oceanview
$7,110
Balcony
$8,672
Suite
$12,610
From
US$5,801
Save 128
Per Person
View Trip
Cruise
 (13)

22 Days (21 Nights) Barcelona to Trieste
Cruise Line: Cunard
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy, Croatia
Inside
$3,899
Oceanview
$4,249
Balcony
$5,449
Suite
$11,543
From
US$3,899
Per Person
View Trip
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Departure: 09 September 2027
Visit: Italy, Sicily, Montenegro, Croatia, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,820
Suite
$18,359
From
US$17,820
Save 18,478
Per Person
View Trip
Cruise
 (8)

38 Days (37 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Departure: 13 August 2026
Visit: Spain, France, Monaco, Italy (+6 more), Sicily, Montenegro, Slovenia, Croatia, Greece, Turkey
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$13,871
Balcony
-
Suite
$25,578
From
US$13,871
Save 338
Per Person
View Trip
Cruise
 (13)

22 Days (21 Nights) Istanbul to Barcelona
Cruise Line: Cunard
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy, Croatia, Spain
Inside
$4,179
Oceanview
$4,479
Balcony
$5,429
Suite
$12,216
From
US$4,179
Per Person
View Trip
Cruise
 (8)

28 Days (27 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Departure: 02 June 2028
Visit: Spain, France, Italy, Sicily (+6 more), Malta, Montenegro, Croatia, Slovenia, Greece, Turkey
Azamara Always Included
Exclusive Savings
Inside
$8,230
Oceanview
$9,200
Balcony
$10,694
Suite
$16,329
From
US$8,230
Save 179
Per Person
View Trip
New ReleaseCruise

33 Days (32 Nights) Istanbul to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 12 August 2028
Visit: Turkey, Greece, Montenegro, Croatia, Slovenia, Italy, Sicily
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$99,894
Suite
$107,363
From
US$99,894
Save 2,956
Per Person
View Trip
Cruise
 (5)

32 Days (31 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Departure: 13 September 2026
Visit: Spain, France, Monaco, Italy (+6 more), Sicily, Montenegro, Slovenia, Croatia, Greece, Turkey
Azamara Always Included
Exclusive Savings
Inside
$11,121
Oceanview
$12,362
Balcony
-
Suite
$19,715
From
US$11,121
Save 268
Per Person
View Trip
Cruise
 (1)

20 Days (19 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Departure: 19 July 2027
Visit: Italy, Sicily, Greece, Turkey, Albania, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$5,777
Oceanview
$6,262
Balcony
$9,463
Suite
$13,246
From
US$5,777
Save 6,021
Per Person
View Trip
Cruise

36 Days (35 Nights) Barcelona to Athens
Cruise Line: Seabourn
Departure: 25 September 2027
Visit: Spain, France, Corsica, Sardinia (+8 more), Italy, Sicily, Malta, Montenegro, Croatia, Slovenia, Greece, Turkey
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$34,460
Suite
$48,572
From
US$34,460
Save 639
Per Person
View Trip
Cruise
 (8)

45 Days (44 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Departure: 11 June 2026
Visit: Spain, France, Corsica, Monaco (+6 more), Italy, Montenegro, Croatia, Slovenia, Greece, Turkey
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$15,941
Balcony
-
Suite
-
From
US$15,941
Save 388
Per Person
View Trip
Cruise
 (1)

15 Days (14 Nights) Monte Carlo to Istanbul
Cruise Line: Oceania Cruises
Departure: 17 July 2026
Visit: Monaco, Sicily, Malta, Croatia, Montenegro, Greece, Turkey
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$3,158
Oceanview
$3,316
Balcony
$5,537
Suite
$7,167
From
US$3,158
Save 6,740
Per Person
View Trip
Cruise

15 Days (14 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Departure: 07 August 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,527
Suite
$11,097
From
US$8,527
Save 8,971
Per Person
View Trip
Cruise

38 Days (37 Nights) Barcelona to Istanbul
Cruise Line: Seabourn
Departure: 15 July 2027
Visit: Spain, France, Monaco, Italy (+9 more), Corsica, Sardinia, Sicily, Malta, Albania, Croatia, Montenegro, Greece, Turkey
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$37,011
Suite
-
From
US$37,011
Save 688
Per Person
View Trip
Cruise

23 Days (22 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 02 April 2026
Visit: Spain, Italy, Malta, Sicily (+4 more), Greece, Montenegro, Croatia, Turkey
Inside
-
Oceanview
-
Balcony
-
Suite
$21,675
From
US$21,675
Per Person
View Trip
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Departure: 22 July 2027
Visit: Italy, Sicily, Montenegro, Croatia, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,036
Suite
$17,281
From
US$17,036
Save 17,662
Per Person
View Trip
Cruise

19 Days (18 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Departure: 02 September 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,640
Suite
$21,747
From
US$19,640
Save 20,358
Per Person
View Trip
Cruise

22 Days (21 Nights) Rome to Istanbul
Cruise Line: Seabourn
Departure: 02 October 2027
Visit: Italy, Sicily, Malta, Montenegro (+4 more), Croatia, Slovenia, Greece, Turkey
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,598
Suite
$29,144
From
US$21,598
Save 401
Per Person
View Trip
Cruise

29 Days (28 Nights) Barcelona to Istanbul
Cruise Line: Seabourn
Departure: 25 September 2027
Visit: Spain, France, Corsica, Sardinia (+8 more), Italy, Sicily, Malta, Montenegro, Croatia, Slovenia, Greece, Turkey
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$28,276
Suite
-
From
US$28,276
Save 523
Per Person
View Trip
Cruise
 (1)

26 Days (25 Nights) Rome to London
Cruise Line: Cunard
Departure: 21 September 2026
Visit: Italy, Sicily, Greece, Turkey, Spain, Portugal, England
Bonus Onboard Credit
Inside
$4,489
Oceanview
$5,019
Balcony
$7,010
Suite
-
From
US$4,489
Per Person
View Trip
Results: 691-715 of 715

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