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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
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780 Cruises (900 Cruise Departures)
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 01 July 2026
Visit: France, Corsica, Sardinia, Spain
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$10,200
Balcony
$10,900
Suite
-
From
US$10,200
Save 1,500
Per Person
View Trip
15 Day An Extended Journey Through Timeless Coastal Beauty & Cultural Splendour with Explora Journeys
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 31 August 2026
Visit: Spain, Tunisia, Malta, Sicily, Italy, Monaco, France
Inside
-
Oceanview
-
Balcony
-
Suite
$11,720
From
US$11,720
Per Person
View Trip
10 Day Under The Tuscan Sunset with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 17 June 2027
Visit: Spain, Corsica, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,499
Suite
$11,649
From
US$11,499
Save 11,499
Per Person
View Trip
12 Day Rome to Barcelona (Monaco Grand Prix) with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 May 2026
Visit: Italy, Corsica, Monaco, Spain
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,500
Suite
$17,100
From
US$9,500
Save 3,500
Per Person
View Trip
8 Day A Journey Of Mediterranean Wonders From Ancient Secrets To Modren Buzzing Vibes with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 05 October 2026
Visit: Italy, Monaco, France, Spain
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$5,935
From
US$5,935
Per Person
View Trip
8 Day Island Hopping Aboard Le Ponant, from Athens to Dubrovnik with Ponant
Cruise

8 Days (7 Nights) Athens to Dubrovnik
Cruise Line: Ponant
Ship: Le Ponant
Departure: 18 July 2026
Visit: Greece, Montenegro, Croatia
Inside
-
Oceanview
$15,950
Balcony
$18,680
Suite
$37,230
From
US$15,950
Per Person
View Trip
8 Day Pompeii, Sicily, Malta & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Monte Carlo to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 14 October 2028
Visit: Monaco, Italy, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$5,219
Suite
$8,369
From
US$5,219
Per Person
View Trip
15 Day Mediterranean Interlude with Regent Seven Seas
Cruise

15 Days (14 Nights) Athens to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 29 January 2027
Visit: Greece, Sicily, Malta, Tunisia, Spain, Portugal
Exclusive Savings
Inside
-
Oceanview
$11,699
Balcony
$13,149
Suite
$14,099
From
US$11,699
Save 11,699
Per Person
View Trip
13 Day Southern Europe Sojourn with Oceania Cruises
Cruise

13 Days (12 Nights) Barcelona to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 25 June 2026
Visit: Spain, France, Monaco, Corsica (+5 more), Italy, Sicily, Greece, Montenegro, Croatia
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,630
Suite
-
From
US$6,630
Save 8,968
Per Person
View Trip
7 Day Monte Carlo to Barcelona with Silversea
Cruise

7 Days (6 Nights) Monte Carlo to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 21 June 2026
Visit: Monaco, France, Spain
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,100
Suite
$8,600
From
US$6,100
Save 3,500
Per Person
View Trip
13 Day Italian & Adriatic Icons: Rome to Dubrovnik with Emerald Cruises
New ReleaseCruise

13 Days (12 Nights) Rome to Dubrovnik
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departures: May 2027 to Sep 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$9,612
Balcony
-
Suite
$12,927
From
US$9,612
Save 2,683
Per Person
View Trip
19 Day Italia In Full with Regent Seven Seas
Cruise

19 Days (18 Nights) Barcelona to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 May 2027
Visit: Spain, France, Monaco, Italy (+5 more), Sicily, Sardinia, Montenegro, Croatia, Slovenia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$22,399
Suite
$23,799
From
US$22,399
Save 22,399
Per Person
View Trip
20 Day Mediterranean And Greek Islands with Cunard
Cruise

20 Days (19 Nights) London to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 20 September 2026
Visit: England, Spain, Greece, Sardinia, Gibraltar
Inside
$3,349
Oceanview
$4,709
Balcony
$5,629
Suite
$12,129
From
US$3,349
Per Person
View Trip
11 Day French Riviera & Amalfi Coast to Malta with Scenic
New ReleaseCruise

11 Days (10 Nights) Nice to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2028
Visit: Malta, Sicily, Italy, Corsica, Monaco, France
Inside
-
Oceanview
-
Balcony
$13,395
Suite
$21,595
From
US$13,395
Per Person
View Trip
9 Day Isle of Beauty & Italian Shores with Ponant
Cruise

9 Days (8 Nights) Nice to Nice
Cruise Line: Ponant
Ships: Le Boreal, Le Dumont d’Urville
Departures: Jul 2026 to Jul 2026
Visit: France, Corsica, Italy
Inside
-
Oceanview
$7,960
Balcony
$7,150
Suite
$13,370
From
US$7,150
Per Person
View Trip
29 Day Hidden Harbors Of France, Spain, Italy & Greece with Seabourn
Cruise

29 Days (28 Nights) Rome to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 September 2028
Visit: Italy, France, Spain, Sardinia (+7 more), Corsica, Monaco, Sicily, Malta, Montenegro, Croatia, Greece
Inside
-
Oceanview
-
Balcony
$18,809
Suite
$30,149
From
US$18,809
Per Person
View Trip
10 Day Pasta To Paella with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 April 2028
Visit: Italy, Sardinia, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,699
Suite
$6,299
From
US$3,699
Save 3,699
Per Person
View Trip
11 Day A Journey through Mediterranean Wonders & Ancient Echoes with Explora Journeys
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 March 2027
Visit: Spain, Italy, Malta, Tunisia, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$5,495
From
US$5,495
Per Person
View Trip
8 Day A Journey Of Shimmering Shores & Timeless Mediterranean Treasures with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Jun 2026 to Sep 2026
Visit: Italy, Corsica, France, Spain
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$4,600
From
US$4,600
Per Person
View Trip
10 Day Fountains To Flamenco with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 09 November 2027
Visit: Italy, Sardinia, Corsica, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,499
Suite
$6,699
From
US$4,499
Save 4,499
Per Person
View Trip
12 Day Spanish Flavors & Rhythms with Regent Seven Seas
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 11 October 2027
Visit: Italy, Monaco, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,249
Suite
$12,999
From
US$11,249
Save 11,249
Per Person
View Trip
13 Day Civitavecchia (Rome) to Athens (Piraeus) with Silversea
Cruise

13 Days (12 Nights) Rome to Athens
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 10 October 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$8,600
Balcony
$9,500
Suite
$30,600
From
US$8,600
Save 1,500
Per Person
View Trip
22 Day Exploring Italy, Malta, Greece & Evening At Ephesus with Seabourn
Cruise

22 Days (21 Nights) Rome to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Italy, Sicily, Malta, Montenegro, Croatia, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$13,409
Suite
$22,679
From
US$13,409
Per Person
View Trip
10 Day Italian Grace with Regent Seven Seas
Cruise

10 Days (9 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 17 February 2029
Visit: Greece, Montenegro, Croatia, Italy, Malta, Sicily
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,299
Suite
$9,699
From
US$8,299
Save 8,299
Per Person
View Trip
16 Day Barcelona to Civitavecchia with Silversea
Cruise

16 Days (15 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 25 July 2026
Visit: Spain, Corsica, France, Monaco, Italy
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$7,500
Suite
$11,800
From
US$7,500
Per Person
View Trip
11 Day Heavenly Mediterranean Islands with Regent Seven Seas
Cruise

11 Days (10 Nights) Trieste to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 25 October 2027
Visit: Italy, Greece, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,099
Suite
$12,699
From
US$12,099
Save 12,099
Per Person
View Trip
11 Day Riviera Icons & Moorish Andalusia with Seabourn
Cruise

11 Days (10 Nights) Genoa to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 23 May 2028
Visit: Italy, France, Spain, Morocco, Portugal
Inside
-
Oceanview
-
Balcony
$7,999
Suite
$12,999
From
US$7,999
Per Person
View Trip
15 Day An Extended Journey Through Antique Treasures, Mediterranean Flavours & Island Calm with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 07 September 2026
Visit: Italy, Monaco, France, Spain, Sardinia, Corsica
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$11,440
From
US$11,440
Per Person
View Trip
9 Day Monte Carlo to Fusina (Venice) with Silversea
Cruise

9 Days (8 Nights) Monte Carlo to Venice
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 June 2027
Visit: Monaco, Malta, Sicily, Italy, Croatia
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,900
Suite
$11,300
From
US$6,900
Save 1,500
Per Person
View Trip
15 Day Montenegro, Italy, Greek Isles & Evening At Ephesus with Seabourn
Cruise

15 Days (14 Nights) Dubrovnik to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Croatia, Montenegro, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$8,909
Suite
$14,579
From
US$8,909
Per Person
View Trip
Results: 751-780 of 780

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