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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 745 unique cruise itineraries with 1204 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 848 departures starting between April 2026 and November 2028.
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745 Cruises (848 Cruise Departures)
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 01 April 2027
Visit: France, Italy, Malta, Sicily, Corsica
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$8,300
Balcony
$9,900
Suite
$14,900
From
US$8,300
Save 1,500
Per Person
View Trip
8 Day A Journey Of Antique Treasures To Sumptuous Catalan with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 07 September 2026
Visit: Italy, Monaco, France, Spain
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$5,320
From
US$5,320
Per Person
View Trip
9 Day Barcelona to Civitavecchia (Rome) with Silversea
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 21 May 2027
Visit: Spain, Sardinia, Sicily, Malta, Italy
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,900
Suite
$11,000
From
US$6,900
Save 2,500
Per Person
View Trip
10 Day The Great Corsican Loop with Ponant
Cruise

10 Days (9 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departure: 14 May 2026
Visit: France, Corsica, Italy
Inside
-
Oceanview
$20,000
Balcony
$26,930
Suite
$28,900
From
US$20,000
Per Person
View Trip
15 Day Montenegro, Italy, Greek Isles & Evening At Ephesus with Seabourn
Cruise

15 Days (14 Nights) Dubrovnik to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Croatia, Montenegro, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$9,899
Suite
$16,199
From
US$9,899
Per Person
View Trip
31 Day Ultimate Voyage: Mediterranean Rivieras & Atlantic Gems: Italy to Africa with Scenic
New ReleaseCruise

31 Days (30 Nights) Rome to Dakar
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 04 October 2028
Visit: Italy, Corsica, Monaco, France (+6 more), Spain, Gibraltar, Morocco, Portugal, Cape Verde, Senegal
Inside
-
Oceanview
-
Balcony
$98,470
Suite
$105,470
From
US$98,470
Per Person
View Trip
8 Day Spellbinding Rivieras with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 16 April 2027
Visit: Spain, France, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$5,949
From
US$3,799
Save 3,799
Per Person
View Trip
8 Day Under Sail from the Riviera to Sicily with Ponant
Cruise

8 Days (7 Nights) Nice to Palermo
Cruise Line: Ponant
Ship: Le Ponant
Departure: 01 June 2027
Visit: France, Italy, Sicily
Inside
-
Oceanview
$11,380
Balcony
$18,350
Suite
$20,450
From
US$11,380
Per Person
View Trip
8 Day Mystical Italy & Croatia with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 June 2027
Visit: Italy, Sicily, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,149
Suite
$10,299
From
US$9,149
Save 9,149
Per Person
View Trip
29 Day Greece, Croatia, Slovenia & French Yacht Harbors with Seabourn
Cruise

29 Days (28 Nights) Athens to Monte Carlo
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 20 May 2028
Visit: Greece, Montenegro, Croatia, Slovenia (+7 more), Italy, Malta, France, Spain, Sardinia, Corsica, Monaco
Inside
-
Oceanview
-
Balcony
$20,699
Suite
-
From
US$20,699
Per Person
View Trip
10 Day Mediterranean Rivieras: Rome to Barcelona with Scenic
New ReleaseCruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 04 October 2028
Visit: Italy, Corsica, Monaco, France, Spain
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,642
Suite
$14,668
From
US$13,642
Save 2,228
Per Person
View Trip
8 Day Yacht Harbors Of The Cote D'azur with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Jul 2028 to Sep 2028
Visit: Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$5,799
Suite
$9,299
From
US$5,799
Per Person
View Trip
9 Day A Celebration of Art: The French & Italian Rivieras and Corsica with Ponant
Cruise

9 Days (8 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 10 July 2026
Visit: France, Corsica, Italy
Inside
-
Oceanview
-
Balcony
$9,110
Suite
$16,030
From
US$9,110
Per Person
View Trip
6 Day A Journey Through Iberian Soul & Moorish Echoes with Explora Journeys
Cruise

6 Days (5 Nights) Barcelona to Cartagena
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 03 May 2026
Visit: Spain, Morocco
Inside
-
Oceanview
-
Balcony
-
Suite
$3,375
From
US$3,375
Per Person
View Trip
36 Day Ultimate Mediterranean: From Spain To Turkey with Seabourn
Cruise

36 Days (35 Nights) Barcelona to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 25 September 2027
Visit: Spain, France, Corsica, Sardinia (+8 more), Italy, Sicily, Malta, Montenegro, Croatia, Slovenia, Greece, Turkey
Yours to Explore
Inside
-
Oceanview
-
Balcony
$35,499
Suite
$50,099
From
US$35,499
Per Person
View Trip
12 Day Majestic Malaga & Storied Seville with Regent Seven Seas
Cruise

12 Days (11 Nights) Barcelona to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 18 April 2027
Visit: Spain, France, Morocco, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,899
Suite
$13,849
From
US$12,899
Save 12,899
Per Person
View Trip
11 Day Barcelona to Rome with Silversea
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 28 September 2026
Visit: Spain, France, Monaco, Italy
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$7,500
Balcony
$7,900
Suite
$7,700
From
US$7,500
Save 2,500
Per Person
View Trip
15 Day Hidden Gems Of Montenegro, Greece, Croatia & Slovenia with Seabourn
Cruise

15 Days (14 Nights) Dubrovnik to Venice
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 October 2028
Visit: Croatia, Montenegro, Italy, Greece, Slovenia
Inside
-
Oceanview
-
Balcony
$10,499
Suite
$16,799
From
US$10,499
Per Person
View Trip
6 Day Nice to Malaga with Silversea
Cruise

6 Days (5 Nights) Nice to Malaga
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 30 August 2026
Visit: France, Spain
Last Minute Fare
Inside
-
Oceanview
$2,950
Balcony
$3,150
Suite
-
From
US$2,950
Per Person
View Trip
8 Day Barcelona to Rome with Silversea
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 07 September 2026
Visit: Spain, Sardinia, Tunisia, Sicily, Italy
Last Minute Fare
All-Inclusive Plus Fare
All-Inclusive Fare
Inside
-
Oceanview
$5,250
Balcony
$5,950
Suite
$10,800
From
US$5,250
Per Person
View Trip
10 Day Lisbon to Civitavecchia (Rome) with Silversea
Cruise

10 Days (9 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 06 September 2027
Visit: Portugal, Spain, France, Italy
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$6,600
Balcony
$7,100
Suite
$6,800
From
US$6,600
Save 2,500
Per Person
View Trip
9 Day Spanish & French Coastal Charm with Seabourn
Cruise

9 Days (8 Nights) Barcelona to Monte Carlo
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 15 July 2027
Visit: Spain, France, Monaco
Yours to Explore
Inside
-
Oceanview
-
Balcony
$8,999
Suite
$13,999
From
US$8,999
Per Person
View Trip
15 Day French Yacht Harbors, Southern France & Corsica with Seabourn
Cruise

15 Days (14 Nights) Rome to Monte Carlo
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 September 2028
Visit: Italy, France, Spain, Sardinia, Corsica, Monaco
Inside
-
Oceanview
-
Balcony
$10,499
Suite
$16,799
From
US$10,499
Per Person
View Trip
10 Day Nice to Nice with Silversea
Cruise

10 Days (9 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 06 July 2027
Visit: France, Italy, Sicily, Malta
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$5,900
Balcony
$6,600
Suite
$9,800
From
US$5,900
Save 2,500
Per Person
View Trip
13 Day Monte Carlo to Lisbon with Silversea
Cruise

13 Days (12 Nights) Monte Carlo to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 15 November 2027
Visit: Monaco, France, Spain, Morocco, Portugal
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,500
Suite
$16,900
From
US$7,500
Save 1,500
Per Person
View Trip
Results: 721-745 of 745

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