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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 605 unique cruise itineraries with 2 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 652 departures starting between February 2026 and October 2028.
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605 Cruises (652 Cruise Departures)
8 Day Viva Italia with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 23 April 2027
Visit: Italy, Sicily, Montenegro, Croatia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,416
Suite
$4,677
From
US$3,416
Save 3,582
Per Person
View Trip
15 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 22 June 2026
Visit: Spain, Sardinia, Corsica, Sicily (+4 more), Italy, Greece, Montenegro, Croatia
Inside
$2,399
Oceanview
$2,689
Balcony
$3,959
Suite
$6,113
From
US$2,399
Per Person
View Trip
8 Day Mount Etna To Lake Bled with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 29 July 2027
Visit: Italy, Sicily, Greece, Croatia, Slovenia
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,099
Oceanview
$2,299
Balcony
$3,611
Suite
$5,066
From
US$2,099
Save 2,099
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 10 September 2027
Visit: Spain, Malta, Montenegro, Croatia (+5 more), Italy, Greece, Sicily, France, Corsica
Inside
$2,749
Oceanview
$3,129
Balcony
$3,889
Suite
$10,463
From
US$2,749
Per Person
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 May 2026
Visit: Spain, France, Italy, Corsica (+4 more), Sicily, Greece, Montenegro, Croatia
Inside
-
Oceanview
$3,659
Balcony
$4,449
Suite
$10,393
From
US$3,659
Per Person
View Trip
15 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 July 2026
Visit: Italy, France, Corsica, Spain, Sicily, Greece, Montenegro
Inside
$2,399
Oceanview
$2,609
Balcony
$2,739
Suite
$6,074
From
US$2,399
Per Person
View Trip
8 Day Malta, Croatia And Montenegro with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2027 to Sep 2027
Visit: Spain, Malta, Montenegro, Croatia, Italy
Inside
$949
Oceanview
$1,049
Balcony
$1,199
Suite
$2,979
From
US$949
Per Person
View Trip
8 Day Mediterranean Vistas with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 03 August 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia, Slovenia
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,298
Oceanview
$2,492
Balcony
$3,947
Suite
$4,965
From
US$2,298
Save 2,400
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 23 July 2027
Visit: Italy, Spain, Sardinia, Corsica (+4 more), Malta, Croatia, Greece, Sicily
Inside
$2,829
Oceanview
$3,219
Balcony
$3,779
Suite
$8,265
From
US$2,829
Per Person
View Trip
8 Day Greece, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia
Inside
$1,409
Oceanview
$1,609
Balcony
$1,909
Suite
$4,059
From
US$1,409
Per Person
View Trip
8 Day Spotlight On Sparkling Wines with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 October 2026
Visit: Italy, Sicily, Malta, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,709
Suite
$7,954
From
US$7,709
Save 12,389
Per Person
View Trip
8 Day Magical Mediterranean with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 11 June 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,835
Suite
$4,920
From
US$2,835
Save 2,963
Per Person
View Trip
11 Day Italy, Montenegro & Croatia Cruise: Rome, Kotor & Dubrovnik with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 31 October 2027
Visit: Spain, Italy, Sicily, Montenegro, Croatia
Azamara Always Included
Exclusive Savings
Inside
$2,748
Oceanview
$3,340
Balcony
$4,116
Suite
$5,988
From
US$2,748
Save 61
Per Person
View Trip
8 Day Adriatic Reflections with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 April 2027
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$2,639
Oceanview
$3,076
Balcony
$3,464
Suite
$4,773
From
US$2,639
Save 2,759
Per Person
View Trip
13 Day Best Of The Mediterranean Cruise: Monte Carlo, Florence & Venice with Azamara Cruises
Cruise
 (8)

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 08 June 2027
Visit: Spain, France, Monaco, Italy, Montenegro, Croatia, Slovenia
Azamara Always Included
Exclusive Savings
Inside
$5,204
Oceanview
$5,796
Balcony
$7,144
Suite
$10,326
From
US$5,204
Save 125
Per Person
View Trip
13 Day Civitavecchia (Rome) to Fusina (Venice) with Silversea
Cruise

13 Days (12 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 15 September 2027
Visit: Italy, Sicily, Malta, Albania, Montenegro, Croatia
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$7,650
Balcony
$8,730
Suite
$8,100
From
US$7,650
Save 850
Per Person
View Trip
12 Day Italy Cruise: Florence, Rome & Sorrento with Azamara Cruises
Cruise
 (4)

12 Days (11 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 13 September 2026
Visit: Spain, France, Monaco, Italy, Sicily, Montenegro, Slovenia
Azamara Always Included
Exclusive Savings
Inside
$4,807
Oceanview
$5,311
Balcony
-
Suite
-
From
US$4,807
Save 122
Per Person
View Trip
11 Day Italy Intensive Cruise: Florence, Rome & Amalfi with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 May 2026
Visit: France, Italy, Sicily, Montenegro
Azamara Always Included
Exclusive Savings
Inside
$3,049
Oceanview
$3,602
Balcony
$4,863
Suite
$7,792
From
US$3,049
Save 70
Per Person
View Trip
12 Day Best Of The Mediterranean Cruise: Monte Carlo, Amalfi & Venice with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 24 April 2027
Visit: Spain, France, Monaco, Italy, Montenegro, Croatia, Slovenia
Azamara Always Included
Exclusive Savings
Inside
$3,327
Oceanview
$3,860
Balcony
$4,908
Suite
$7,517
From
US$3,327
Save 72
Per Person
View Trip
22 Day Italy, France, Spain And Adriatic with Cunard
Cruise
 (1)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Visit: Italy, Sicily, Greece, Montenegro (+4 more), Croatia, Malta, Spain, Corsica
Inside
$3,669
Oceanview
$3,879
Balcony
-
Suite
$9,403
From
US$3,669
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 28 May 2027
Visit: Italy, Malta, Montenegro, Croatia, Sicily, Spain, Corsica
Inside
$3,599
Oceanview
$3,969
Balcony
$4,729
Suite
$9,819
From
US$3,599
Per Person
View Trip
13 Day Portsmouth To Venice Grand Voyage with Azamara Cruises
Cruise
 (8)

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 March 2027
Visit: Spain, France, Italy, Sicily, Montenegro, Croatia
Azamara Always Included
Exclusive Savings
Inside
$3,804
Oceanview
$4,367
Balcony
$5,560
Suite
$7,966
From
US$3,804
Save 85
Per Person
View Trip
15 Day Italy, Greece And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 20 August 2027
Visit: Spain, Malta, Montenegro, Croatia, Italy, Greece, Sicily
Inside
$1,749
Oceanview
$1,949
Balcony
$2,199
Suite
$5,579
From
US$1,749
Per Person
View Trip
19 Day Italia In Full with Regent Seven Seas
Cruise

19 Days (18 Nights) Barcelona to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 May 2027
Visit: Spain, France, Monaco, Italy (+5 more), Sicily, Sardinia, Montenegro, Croatia, Slovenia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,982
Suite
$16,207
From
US$14,982
Save 23,516
Per Person
View Trip
29 Day Mediterranean, Adriatic, Greece And Turkey with Cunard
Cruise
 (13)

29 Days (28 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 May 2027
Visit: Spain, Sicily, Greece, Turkey (+4 more), Italy, Malta, Montenegro, Croatia
Inside
$4,729
Oceanview
$5,179
Balcony
$5,589
Suite
$11,784
From
US$4,729
Per Person
View Trip
22 Day Greece, Turkey, Italy And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 May 2027
Visit: Spain, Sicily, Greece, Turkey (+4 more), Italy, Malta, Montenegro, Croatia
Inside
$3,519
Oceanview
$3,969
Balcony
$4,359
Suite
$9,068
From
US$3,519
Per Person
View Trip
11 Day Extravagant Ionian Journey with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 02 September 2026
Visit: Spain, Italy, Malta, Croatia, Slovenia
Exclusive Savings
Inside
-
Oceanview
$7,176
Balcony
$8,842
Suite
$9,626
From
US$7,176
Save 12,822
Per Person
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 August 2026
Visit: Italy, Spain, France, Sardinia (+4 more), Sicily, Greece, Montenegro, Croatia
Inside
$3,959
Oceanview
$4,179
Balcony
$5,249
Suite
$15,977
From
US$3,959
Per Person
View Trip
18 Day European Artistry with Oceania Cruises
Cruise
 (1)

18 Days (17 Nights) Lisbon to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 24 July 2026
Visit: Portugal, Spain, Gibraltar, Corsica (+6 more), Italy, Sicily, Greece, Montenegro, Croatia, Slovenia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$5,281
Oceanview
-
Balcony
$8,870
Suite
$12,023
From
US$5,281
Save 5,517
Per Person
View Trip
22 Day Italy, Spain And Adriatic with Cunard
Cruise
 (1)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 June 2026
Visit: Italy, Sicily, Greece, Montenegro (+4 more), Croatia, Malta, Spain, France
Inside
$3,699
Oceanview
-
Balcony
$6,562
Suite
-
From
US$3,699
Per Person
View Trip
Results: 421-450 of 605

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