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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
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780 Cruises (900 Cruise Departures)
8 Day Chianti, Rose & Cava with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 28 November 2027
Visit: Spain, France, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,649
Suite
$8,699
From
US$7,649
Save 7,649
Per Person
View Trip
9 Day Ancient Cities of the Mediterranean with Ponant
Cruise

9 Days (8 Nights) Athens to Valletta
Cruise Line: Ponant
Ships: Le Champlain, Le Dumont d’Urville
Departures: Nov 2026 to Oct 2027
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$7,880
Suite
$13,370
From
US$7,880
Per Person
View Trip
10 Day Medieval Mediterranean with Oceania Cruises
Cruise

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 19 February 2028
Visit: Turkey, Greece, Malta, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,449
Suite
$5,299
From
US$3,449
Save 3,449
Per Person
View Trip
8 Day Mediterranean Muse with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 13 August 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,149
Suite
$5,149
From
US$3,149
Save 3,149
Per Person
View Trip
13 Day An Extended Journey To Mediterranean Elegance: From F1 Race Weekend To Calming Scenic Shores with Explora Journeys
Cruise

13 Days (12 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 03 June 2026
Visit: Monaco, Italy, Sicily, Malta, Spain
Ocean View in Monaco
City View in Monaco
Inside
-
Oceanview
-
Balcony
-
Suite
$23,500
From
US$23,500
Per Person
View Trip
20 Day Marvels Of The Mediterranean with Oceania Cruises
Cruise

20 Days (19 Nights) Lisbon to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 26 September 2027
Visit: Portugal, Spain, France, Italy (+4 more), Sicily, Tunisia, Malta, Greece
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,699
Suite
$12,249
From
US$8,699
Save 8,699
Per Person
View Trip
11 Day Pearls of Southern Spain & Portugal with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 08 October 2026
Visit: Portugal, Spain, Morocco
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,289
From
US$11,289
Save 1,056
Per Person
View Trip
10 Day Latin Languages Of Love with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 27 March 2028
Visit: Italy, Sicily, Sardinia, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$6,199
From
US$3,599
Save 3,599
Per Person
View Trip
15 Day An Extended Journey Of Rocky Scenery, Diverse Cultures & Captivating Cities with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 July 2026
Visit: Italy, Monaco, France, Spain, Sardinia, Corsica
Inside
-
Oceanview
-
Balcony
-
Suite
$11,790
From
US$11,790
Per Person
View Trip
12 Day Treasures of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Visit: Italy, Sicily, Malta, Tunisia, Algeria, Spain, Portugal
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,636
Suite
$20,081
From
US$14,636
Save 3,124
Per Person
View Trip
31 Day Hidden Riviera Gems, Malta, Montenegro & Greece with Seabourn
Cruise

31 Days (30 Nights) Athens to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 28 October 2028
Visit: Greece, Montenegro, Croatia, Slovenia (+7 more), Italy, Malta, Monaco, France, Spain, Morocco, Portugal
Inside
-
Oceanview
-
Balcony
$19,079
Suite
$31,859
From
US$19,079
Per Person
View Trip
8 Day Island Hopping Aboard Le Ponant, From Athens to Dubrovnik with Ponant
Cruise

8 Days (7 Nights) Athens to Dubrovnik
Cruise Line: Ponant
Ship: Le Ponant
Departure: 13 July 2027
Visit: Greece, Montenegro, Croatia
Inside
-
Oceanview
$13,510
Balcony
-
Suite
$22,940
From
US$13,510
Per Person
View Trip
16 Day Malta, Italy, Spain & Portugal with Seabourn
Cruise

16 Days (15 Nights) Athens to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 October 2027
Visit: Greece, Malta, Sicily, Sardinia, Spain, Portugal
Inside
-
Oceanview
-
Balcony
$10,624
Suite
$15,469
From
US$10,624
Per Person
View Trip
7 Day Rome to Monte Carlo with Silversea
Cruise

7 Days (6 Nights) Rome to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 09 August 2026
Visit: Italy, France, Monaco
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$3,550
Suite
$7,900
From
US$3,550
Per Person
View Trip
11 Day Barcelona to Lisbon with Silversea
Cruise

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Silversea
Ship: Silver Muse
Departure: 10 August 2026
Visit: Spain, Gibraltar, Morocco, Portugal
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$6,050
Balcony
$6,550
Suite
$13,000
From
US$6,050
Per Person
View Trip
8 Day French Yacht Harbors, Sardinia & Corsica with Seabourn
Cruise

8 Days (7 Nights) Barcelona to Monte Carlo
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 07 October 2028
Visit: Spain, France, Sardinia, Corsica, Monaco
Inside
-
Oceanview
-
Balcony
$5,219
Suite
$8,369
From
US$5,219
Per Person
View Trip
11 Day Italian Tapestry with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 26 March 2029
Visit: Spain, France, Italy, Sardinia, Malta, Sicily
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,999
Suite
$11,499
From
US$9,999
Save 9,999
Per Person
View Trip
20 Day Woven By The Sea with Regent Seven Seas
Cruise

20 Days (19 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 17 March 2029
Visit: Portugal, Morocco, Spain, France (+4 more), Italy, Sardinia, Malta, Sicily
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,899
Suite
$20,299
From
US$17,899
Save 17,899
Per Person
View Trip
7 Day Monte Carlo to Barcelona with Silversea
Cruise

7 Days (6 Nights) Monte Carlo to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 30 August 2026
Visit: Monaco, France, Spain
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$3,350
Suite
$4,850
From
US$3,350
Per Person
View Trip
11 Day Barcelona to Monte Carlo with Silversea
Cruise

11 Days (10 Nights) Barcelona to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 September 2026
Visit: Spain, France, Monaco
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$6,150
Suite
$11,800
From
US$6,150
Per Person
View Trip
11 Day Barcelona to Lisbon with Silversea
Cruise

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Silversea
Ship: Silver Ray
Departure: 03 November 2027
Visit: Spain, Morocco, Portugal
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,800
Suite
$9,900
From
US$5,800
Save 3,000
Per Person
View Trip
12 Day Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Athens to Malaga
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 28 June 2026
Visit: Greece, Sicily, Sardinia, Spain
Inside
-
Oceanview
-
Balcony
$16,780
Suite
$39,990
From
US$16,780
Per Person
View Trip
8 Day Corsican Shores, Under Sail Aboard Le Ponant with Ponant
Cruise

8 Days (7 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departures: May 2026 to Sep 2027
Visit: France, Corsica
Inside
-
Oceanview
$10,020
Balcony
$16,130
Suite
$17,960
From
US$10,020
Per Person
View Trip
10 Day Caesars & Conquistadors with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 15 June 2027
Visit: Italy, Monaco, Spain, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,399
Suite
$6,599
From
US$4,399
Save 4,399
Per Person
View Trip
29 Day France, Italy, Greece & Evening At Ephesus with Seabourn
Cruise

29 Days (28 Nights) Barcelona to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 10 June 2028
Visit: Spain, France, Sardinia, Corsica (+8 more), Monaco, Italy, Sicily, Malta, Montenegro, Croatia, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$18,989
Suite
$30,149
From
US$18,989
Per Person
View Trip
8 Day French Yacht Harbors, Sardinia & Corsica with Seabourn
Cruise

8 Days (7 Nights) Barcelona to Monte Carlo
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 10 June 2028
Visit: Spain, France, Sardinia, Corsica, Monaco
Inside
-
Oceanview
-
Balcony
$5,399
Suite
$8,369
From
US$5,399
Per Person
View Trip
10 Day Barcelona to Barcelona with Silversea
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 25 October 2027
Visit: Spain, France
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,400
Suite
$9,900
From
US$5,400
Save 3,000
Per Person
View Trip
11 Day Monte Carlo to Rome with Silversea
Cruise

11 Days (10 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 08 October 2026
Visit: Monaco, France, Corsica, Italy, Sicily
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,400
Suite
-
From
US$9,400
Save 1,500
Per Person
View Trip
15 Day An Extended Journey Of Exquisite Mediterranean Elegance, Art & History with Explora Journeys
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 04 September 2028
Visit: Italy, Corsica, France, Spain, Tunisia, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$9,310
From
US$9,310
Per Person
View Trip
8 Day Civitavecchia (Rome) to Monte Carlo with Silversea
Cruise

8 Days (7 Nights) Rome to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 03 July 2027
Visit: Italy, Sardinia, Corsica, France, Monaco
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,100
Suite
$7,800
From
US$5,100
Save 3,000
Per Person
View Trip
Results: 421-450 of 780

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