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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 451 unique cruise itineraries from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise in the Mediterranean with 543 departures starting between May 2024 and April 2027.
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451 Cruises (543 Cruise Departures)
15 Day Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Jun 2025 to Sep 2025
Countries Visited: Italy, Greece, Montenegro, Croatia (+2 more), Malta, Spain
INSIDE
$2,677
OCEANVIEW
$3,033
BALCONY
$3,390
SUITE
$7,399
From 2,677
View Trip
22 Day France, Italy And Adriatic with Cunard
Cruise

22 Days (21 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 August 2025
Countries Visited: Italy, France, Sardinia, Sicily (+4 more), Corsica, Spain, Malta, Croatia
INSIDE
$4,055
OCEANVIEW
$4,283
BALCONY
$4,907
SUITE
$10,698
From 4,055
View Trip
8 Day Italy And Adriatic with Cunard
Cruise

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Countries Visited: Spain, Italy, Sicily, Greece (+1 more), Montenegro
INSIDE
$1,783
OCEANVIEW
$1,981
BALCONY
$2,179
SUITE
$4,951
From 1,783
View Trip
11 Day Journey To Dalmatia with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 25 September 2024
Countries Visited: Italy, Sicily, Malta, Greece (+3 more), Albania, Montenegro, Croatia
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,167
SUITE
$15,820
Save 3,773
From 13,167
View Trip
15 Day Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2025 to Jul 2025
Countries Visited: Italy, Greece, Montenegro, Croatia (+1 more), Malta
INSIDE
$2,766
OCEANVIEW
$3,202
BALCONY
$3,578
SUITE
$7,667
From 2,766
View Trip
9 Day From Malta to the Adriatic coast with Ponant
Cruise

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: L'Austral
Departure: 29 May 2024
Countries Visited: Malta, Sicily, Italy, Montenegro (+2 more), Croatia, Slovenia
Exclusive Savings
INSIDE
-
OCEANVIEW
$9,185
BALCONY
$11,625
SUITE
-
Save 175
From 9,185
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 22 June 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+4 more), Greece, Montenegro, Croatia, Malta
INSIDE
$4,857
OCEANVIEW
$5,253
BALCONY
$6,095
SUITE
$12,876
From 4,857
View Trip
15 Day Cruising Greece, Turkey & Saudi Arabia with Abercrombie & Kent
New ReleaseCruise

15 Days (14 Nights) Athens to Jeddah
Operated By: Abercrombie & Kent
Departure: 16 October 2024
Trip Styles: Group, Cruise, Scenic
Countries Visited: Greece, Turkey, Cyprus, Egypt (+2 more), Jordan, Saudi Arabia
Exclusive Deal
Save 3,075
From 36,915
View Trip
15 Day Cruising Greece, Turkey, Egypt & Saudi Arabia with Abercrombie & Kent
New ReleaseCruise

15 Days (14 Nights) Athens to Jeddah
Operated By: Abercrombie & Kent
Departure: 25 October 2025
Trip Styles: Group, Cruise, Scenic
Countries Visited: Greece, Turkey, Cyprus, Egypt (+2 more), Jordan, Saudi Arabia
From 38,260
View Trip
19 Day Holy Land, Egypt & Arabia with Seabourn
Cruise

19 Days (18 Nights) Athens to Dubai
Cruise Line: Seabourn
Ship: Encore
Departure: 02 November 2025
Countries Visited: Greece, Jordan, Egypt, Oman (+1 more), United Arab Emirates
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$11,640
SUITE
$21,233
From 11,640
View Trip
19 Day Ancient Trade Routes with Azamara Cruises
Cruise

19 Days (18 Nights) Athens to Dubai
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 26 October 2024
Countries Visited: Greece, Egypt, Jordan, Saudi Arabia (+2 more), Oman, United Arab Emirates
INSIDE
$6,877
OCEANVIEW
$8,293
BALCONY
$10,961
SUITE
$13,982
From 6,877
View Trip
10 Day A Journey From Athens To Safaga with Explora Journeys
Cruise

10 Days (9 Nights) Athens to Luxor
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 November 2025
Countries Visited: Greece, Cyprus, Israel, Egypt
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$6,608
SUITE
$8,054
From 6,608
View Trip
37 Day Edge Of The Ancient World with Oceania Cruises
Cruise
 (1)

37 Days (36 Nights) Athens to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 11 September 2025
Countries Visited: Greece, Turkey, Cyprus, Malta (+8 more), Tunisia, Sicily, Italy, Corsica, France, Spain, Morocco, Portugal
Exclusive Deal
INSIDE
$15,782
OCEANVIEW
$17,159
BALCONY
$25,088
SUITE
$34,127
Save 2,118
From 15,782
View Trip
27 Day Mediterranean Memories with Oceania Cruises
Cruise
 (1)

27 Days (26 Nights) Athens to Malaga
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 11 September 2025
Countries Visited: Greece, Turkey, Cyprus, Malta (+6 more), Tunisia, Sicily, Italy, Corsica, France, Spain
Exclusive Deal
INSIDE
$11,762
OCEANVIEW
$12,831
BALCONY
$18,484
SUITE
$25,136
Save 2,088
From 11,762
View Trip
24 Day Discover Ancient Wonders of the Mediterranean & Red Sea with Emerald Cruises
New ReleaseCruise
 (1)

24 Days (23 Nights) Athens to Aqaba
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 18 October 2025
Countries Visited: Greece, Turkey, Cyprus, Israel (+2 more), Egypt, Jordan
Exclusive Deal
INSIDE
-
OCEANVIEW
$20,335
BALCONY
-
SUITE
$27,180
Save 7,705
From 20,335
View Trip
15 Day Civilization's Dawn with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Athens to Valletta
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 11 September 2025
Countries Visited: Greece, Turkey, Cyprus, Malta
Exclusive Deal
INSIDE
$6,827
OCEANVIEW
$7,431
BALCONY
$10,639
SUITE
$14,431
Save 2,053
From 6,827
View Trip
23 Day Glory & Glamour with Oceania Cruises
Cruise
 (1)

23 Days (22 Nights) Rome to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Riviera
Departure: 13 August 2024
Countries Visited: Italy, Sicily, Malta, Greece (+5 more), Tunisia, Sardinia, Corsica, France, Monaco
Exclusive Deal
INSIDE
$12,023
OCEANVIEW
$13,855
BALCONY
$15,993
SUITE
$22,458
Save 2,097
From 12,023
View Trip
18 Day Treasures Of The Aegean with Regent Seven Seas
Cruise

18 Days (17 Nights) Monte Carlo to Istanbul
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 April 2025
Countries Visited: Monaco, Italy, Turkey, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,087
SUITE
$19,305
Save 11,203
From 17,087
View Trip
15 Day Aegean Treasures & Italian Allure with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Istanbul
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 22 October 2024
Countries Visited: Spain, Italy, Sicily, Malta (+4 more), Croatia, Montenegro, Greece, Turkey
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
$8,672
BALCONY
$10,421
SUITE
$11,345
Save 13,128
From 8,672
View Trip
29 Day Mediterranean And Greek Islands with Cunard
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 May 2026
Countries Visited: Spain, Greece, Turkey, France (+3 more), Italy, Corsica, Sicily
INSIDE
$5,602
OCEANVIEW
$6,147
BALCONY
$7,137
SUITE
$14,859
From 5,602
View Trip
8 Day Turquoise Coast & Greek Isles with Seabourn
Cruise

8 Days (7 Nights) Athens to Athens
Cruise Line: Seabourn
Ship: Encore
Departure: 04 May 2025
Countries Visited: Greece, Cyprus, Turkey
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$6,908
SUITE
$12,042
From 6,908
View Trip
29 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+3 more), France, Greece, Turkey
INSIDE
$6,246
OCEANVIEW
$6,741
BALCONY
$7,731
SUITE
$17,829
From 6,246
View Trip
11 Day Greco-roman Exploration with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 August 2025
Countries Visited: Italy, Sicily, Malta, Turkey (+1 more), Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,316
SUITE
$14,861
Save 6,174
From 13,316
View Trip
8 Day A Toast To The Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 24 October 2024
Countries Visited: Italy, Sicily, Turkey, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$24,244
Save 4,936
From 24,244
View Trip
10 Day Soul Of Civilization with Oceania Cruises
Cruise

10 Days (9 Nights) Barcelona to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 26 May 2025
Countries Visited: Spain, Malta, Greece, Turkey
Cabin Upgrade Offer
INSIDE
$4,537
OCEANVIEW
$5,606
BALCONY
$5,606
SUITE
$7,131
From 4,537
View Trip
13 Day Immortal Mediterranean with Oceania Cruises
Cruise

13 Days (12 Nights) Barcelona to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 14 September 2025
Countries Visited: Spain, France, Italy, Sicily (+2 more), Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,827
SUITE
$12,371
Save 2,063
From 7,827
View Trip
24 Day Aegean Vistas with Oceania Cruises
Cruise

24 Days (23 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 04 October 2025
Countries Visited: Italy, Sicily, Malta, Greece (+2 more), Turkey, Cyprus
Exclusive Deal
INSIDE
$10,681
OCEANVIEW
$13,285
BALCONY
$15,116
SUITE
$20,977
Save 2,079
From 10,681
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 29 September 2025
Countries Visited: Spain, Greece, Turkey
INSIDE
$1,585
OCEANVIEW
$1,783
BALCONY
$2,031
SUITE
$4,258
From 1,585
View Trip
22 Day Turquoise Coast, Greek Island Gems & Ephesus with Seabourn
Cruise

22 Days (21 Nights) Athens to Dubrovnik
Cruise Line: Seabourn
Ship: Encore
Departure: 04 May 2025
Countries Visited: Greece, Cyprus, Turkey, Italy (+1 more), Croatia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$18,955
SUITE
$31,998
From 18,955
View Trip
15 Day Istanbul, Greek Isles And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 30 September 2024
Countries Visited: Spain, Greece, Turkey, Sicily
INSIDE
$3,221
OCEANVIEW
$3,568
BALCONY
-
SUITE
$7,924
From 3,221
View Trip
Results: 361-390 of 451

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