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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
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780 Cruises (900 Cruise Departures)
15 Day Exploring Pompeii, Sicily, Montenegro & Greece with Seabourn
Cruise

15 Days (14 Nights) Monte Carlo to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 17 June 2028
Visit: Monaco, Italy, Sicily, Malta, Montenegro, Croatia, Greece
Inside
-
Oceanview
-
Balcony
$9,449
Suite
$15,119
From
US$9,449
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 01 July 2026
Visit: France, Corsica, Sardinia, Spain
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$10,200
Balcony
$10,900
Suite
-
From
US$10,200
Save 1,500
Per Person
View Trip
11 Day Iconic Italy & the French Riviera with Scenic
New ReleaseCruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 27 June 2028
Visit: Italy, Monaco, France, Spain
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,998
Suite
$16,326
From
US$13,998
Save 2,247
Per Person
View Trip
11 Day Old World Exploration with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 01 November 2026
Visit: Italy, Malta, Tunisia, Sicily, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,399
Suite
$9,799
From
US$9,399
Save 9,399
Per Person
View Trip
11 Day Pearls of Southern Spain & Portugal with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 08 October 2026
Visit: Portugal, Spain, Morocco
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,289
From
US$11,289
Save 1,056
Per Person
View Trip
7 Day Valletta to Nice with Silversea
Cruise

7 Days (6 Nights) Valletta to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: Jul 2026 to Aug 2026
Visit: Malta, Sicily, Italy, France
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$3,700
Balcony
$4,400
Suite
$10,900
From
US$3,700
Save 2,500
Per Person
View Trip
18 Day Discover the Ancient Treasures of the Mediterranean & Red Sea with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Cairo to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 07 April 2027
Visit: Egypt, Jordan, Israel, Cyprus, Turkey, Greece
Inside
-
Oceanview
-
Balcony
-
Suite
$21,975
From
US$21,975
Per Person
View Trip
7 Day Monte Carlo to Barcelona with Silversea
Cruise

7 Days (6 Nights) Monte Carlo to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 30 August 2026
Visit: Monaco, France, Spain
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$3,350
Suite
$4,850
From
US$3,350
Per Person
View Trip
8 Day Pompeii, Sicily, Malta & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Monte Carlo to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 17 June 2028
Visit: Monaco, Italy, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$5,219
Suite
$8,369
From
US$5,219
Per Person
View Trip
8 Day Monaco, Italy, France & Spain with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 18 September 2027
Visit: Italy, Monaco, France, Spain
Inside
-
Oceanview
-
Balcony
$7,054
Suite
$10,454
From
US$7,054
Per Person
View Trip
15 Day Moroccan & Spanish Delights with Oceania Cruises
Cruise

15 Days (14 Nights) Valletta to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 22 August 2026
Visit: Malta, Tunisia, Spain, Portugal, Morocco
Memorial Day Sale
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,325
Suite
$17,299
From
US$8,325
Save 10,173
Per Person
View Trip
15 Day An Extended Journey Of Verdant Islands, Sandy Shores & Coastal Culture with Explora Journeys
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: May 2027 to Sep 2027
Visit: Spain, Sardinia, France, Italy, Corsica, Monaco
Inside
-
Oceanview
-
Balcony
-
Suite
$9,375
From
US$9,375
Per Person
View Trip
22 Day Mediterranean Mosaic: Croatia, Italy, France & Spain with Seabourn
Cruise

22 Days (21 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy (+5 more), Monaco, France, Spain, Corsica, Sardinia
Inside
-
Oceanview
-
Balcony
$17,509
Suite
$28,049
From
US$17,509
Per Person
View Trip
11 Day Icons Of Antiquity with Regent Seven Seas
Cruise

11 Days (10 Nights) Istanbul to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 30 September 2027
Visit: Turkey, Greece, Cyprus, Israel, Egypt
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,599
Suite
$13,099
From
US$12,599
Save 12,599
Per Person
View Trip
12 Day Stars Of Iberia with Regent Seven Seas
Cruise

12 Days (11 Nights) Lisbon to Valletta
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 09 October 2026
Visit: Portugal, Spain, Sardinia, Tunisia, Sicily, Malta
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,299
Suite
$16,899
From
US$15,299
Save 15,299
Per Person
View Trip
22 Day Discover the Wonders of the Mediterranean & Red Sea with Emerald Cruises
New ReleaseCruise

22 Days (21 Nights) Athens to Aqaba
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 21 October 2026
Visit: Greece, Turkey, Cyprus, Israel, Egypt, Jordan
Inside
-
Oceanview
-
Balcony
-
Suite
$25,740
From
US$25,740
Per Person
View Trip
27 Day Heavenly Holidays with Oceania Cruises
Cruise

27 Days (26 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 08 December 2027
Visit: Greece, Cyprus, Turkey, Malta (+6 more), Sicily, Sardinia, Spain, Morocco, Tunisia, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,899
Suite
$14,999
From
US$10,899
Save 10,899
Per Person
View Trip
15 Day Iberian Wanderlust & Sicilian Dream with Regent Seven Seas
Cruise

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 27 September 2027
Visit: Portugal, Spain, Morocco, Tunisia (+4 more), Sicily, Malta, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,499
Suite
$15,999
From
US$14,499
Save 14,499
Per Person
View Trip
22 Day Mediterranean Mosaic: Dalmatian Gems, Malta & Ephesus with Seabourn
Cruise

22 Days (21 Nights) Rome to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 02 October 2027
Visit: Italy, Sicily, Malta, Montenegro (+4 more), Croatia, Slovenia, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$19,124
Suite
$26,179
From
US$19,124
Per Person
View Trip
10 Day Mediterranean Masterpieces with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 28 February 2028
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,549
Suite
$5,299
From
US$3,549
Save 3,549
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 01 April 2027
Visit: France, Italy, Malta, Sicily, Corsica
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$8,500
Balcony
$10,000
Suite
$12,800
From
US$8,500
Save 1,500
Per Person
View Trip
9 Day Barcelona to Barcelona with Silversea
Cruise

9 Days (8 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 24 April 2027
Visit: Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,900
Suite
$10,000
From
US$5,900
Save 3,000
Per Person
View Trip
8 Day A Journey Of Artistic Marvels & Mediterranean Romance with Explora Journeys
Cruise

8 Days (7 Nights) Venice to Rome
Cruise Line: Explora Journeys
Ship: Explora VI
Departures: Aug 2028 to Oct 2028
Visit: Italy, Croatia, Montenegro, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$4,150
From
US$4,150
Per Person
View Trip
15 Day Montenegro, Italy, Greek Isles & Evening At Ephesus with Seabourn
Cruise

15 Days (14 Nights) Dubrovnik to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Croatia, Montenegro, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$8,909
Suite
$14,579
From
US$8,909
Per Person
View Trip
15 Day Mediterranean Interlude with Regent Seven Seas
Cruise

15 Days (14 Nights) Athens to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 29 January 2027
Visit: Greece, Sicily, Malta, Tunisia, Spain, Portugal
Exclusive Savings
Inside
-
Oceanview
$11,699
Balcony
$13,149
Suite
$14,099
From
US$11,699
Save 11,699
Per Person
View Trip
10 Day Andalusia & Spanish Riviera Gems with Seabourn
Cruise

10 Days (9 Nights) Barcelona to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 18 November 2028
Visit: Spain, Morocco, Portugal
Inside
-
Oceanview
-
Balcony
$5,669
Suite
$13,049
From
US$5,669
Per Person
View Trip
15 Day Dalmatian Gems, Malta, Italy & Greece with Seabourn
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 02 October 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia, Slovenia, Greece
Inside
-
Oceanview
-
Balcony
$12,494
Suite
$17,764
From
US$12,494
Per Person
View Trip
12 Day Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Athens to Malaga
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 28 June 2026
Visit: Greece, Sicily, Sardinia, Spain
Inside
-
Oceanview
-
Balcony
$16,780
Suite
$39,990
From
US$16,780
Per Person
View Trip
7 Day Valletta to Nice with Silversea
Cruise

7 Days (6 Nights) Valletta to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 13 June 2026
Visit: Malta, Sicily, Italy, Corsica, France
Last Minute Fare
Inside
-
Oceanview
$4,350
Balcony
$4,750
Suite
-
From
US$4,350
Per Person
View Trip
15 Day Exploring Italy, Malta, Montenegro & Greece with Seabourn
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Italy, Sicily, Malta, Montenegro, Croatia, Greece
Inside
-
Oceanview
-
Balcony
$8,909
Suite
$15,389
From
US$8,909
Per Person
View Trip
Results: 361-390 of 780

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