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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
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780 Cruises (900 Cruise Departures)
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 23 July 2027
Visit: Italy, Spain, Sardinia, Corsica
Bonus Onboard Credit
Value Fare
Inside
$1,179
Oceanview
$1,279
Balcony
$1,349
Suite
$2,549
From
US$1,179
Per Person
View Trip
8 Day Spain, France & Italy Cruise: Palamos, Marseille & Rome with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 08 April 2028
Visit: Spain, France, Monaco, Italy
Azamara Always Included
Inside
$1,609
Oceanview
$1,739
Balcony
$2,149
Suite
$3,019
From
US$1,609
Per Person
View Trip
11 Day Athens (Piraeus) to Fusina (Venice) with Silversea
Cruise
 (1)

11 Days (10 Nights) Athens to Venice
Cruise Line: Silversea
Ship: Silver Nova
Departure: 25 April 2027
Visit: Greece, Montenegro, Italy, Croatia, Slovenia
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,600
Suite
$12,000
From
US$7,600
Save 1,500
Per Person
View Trip
15 Day Italy, Spain And Adriatic with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Visit: Italy, Greece, Montenegro, Croatia, Malta, Spain
Inside
$2,499
Oceanview
$2,649
Balcony
$3,259
Suite
$5,219
From
US$2,499
Per Person
View Trip
8 Day Mediterranean Passage with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 December 2026
Visit: Italy, Corsica, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$2,887
Balcony
$2,550
Suite
$3,375
From
US$2,550
Save 4,248
Per Person
View Trip
43 Day Lisbon To Athens Grand Voyage with Azamara Cruises
Cruise
 (3)

43 Days (42 Nights) Lisbon to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 March 2028
Visit: Portugal, Spain, Morocco, Gibraltar (+8 more), France, Monaco, Italy, Sicily, Montenegro, Slovenia, Croatia, Greece
Azamara Always Included
Inside
$10,739
Oceanview
$11,469
Balcony
$13,759
Suite
$18,759
From
US$10,739
Per Person
View Trip
9 Day France & Italy Cruise: Marseille, Nice, & Florence with Azamara Cruises
Cruise
 (5)

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 21 April 2028
Visit: Spain, France, Monaco, Italy
Azamara Always Included
Inside
$1,859
Oceanview
$2,019
Balcony
$2,479
Suite
$3,479
From
US$1,859
Per Person
View Trip
11 Day Italy & Spain Cruise: Florence, Marseille & Barcelona with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 03 March 2027
Visit: Italy, France, Spain
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$1,959
Oceanview
$2,249
Balcony
$2,549
Suite
$3,869
From
US$1,959
Per Person
View Trip
11 Day Italy, Montenegro & Croatia Cruise: Rome, Kotor & Dubrovnik with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 31 October 2027
Visit: Spain, Italy, Sicily, Montenegro, Croatia
Azamara Always Included
Inside
$3,989
Oceanview
$4,859
Balcony
$5,999
Suite
$8,759
From
US$3,989
Per Person
View Trip
8 Day Regards From The Riviera with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 September 2027
Visit: Italy, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,099
Oceanview
$2,249
Balcony
$3,499
Suite
$4,749
From
US$2,099
Save 2,099
Per Person
View Trip
15 Day Mediterranean And Croatia with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 22 September 2028
Visit: Italy, Malta, Croatia, Greece, Sicily, Spain
Cunard Fare
Value Fare
Inside
$2,979
Oceanview
$3,339
Balcony
$4,149
Suite
$7,479
From
US$2,979
Per Person
View Trip
15 Day Iberia & Italian Treasures with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 21 December 2026
Visit: Portugal, Spain, France, Italy, Corsica
Memorial Day Sale
Your World Inclusions
Exclusive Savings
Inside
$3,637
Oceanview
$3,862
Balcony
$5,775
Suite
$7,800
From
US$3,637
Save 6,061
Per Person
View Trip
16 Day Mediterranean And Greek Islands with Cunard
Cruise
 (13)

16 Days (15 Nights) London to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 18 May 2028
Visit: England, Spain, Corsica, Italy, Sicily, Greece, Turkey
Cunard Fare
Value Fare
Inside
$3,059
Oceanview
$3,374
Balcony
$4,184
Suite
$7,379
From
US$3,059
Per Person
View Trip
6 Day Grand Prix Weekend Cruise: Barcelona, Saint Tropez & Nice with Azamara Cruises
Cruise
 (8)

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 03 June 2027
Visit: Spain, France
Azamara Always Included
Inside
$2,109
Oceanview
$2,289
Balcony
$2,769
Suite
$3,979
From
US$2,109
Per Person
View Trip
10 Day Epicurean Odyssey with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 27 September 2027
Visit: Spain, France, Monaco, Italy, Corsica, Sardinia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,499
Oceanview
$2,749
Balcony
$4,549
Suite
$6,299
From
US$2,499
Save 2,499
Per Person
View Trip
8 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 November 2027
Visit: Italy, France, Spain
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,200
Suite
$7,400
From
US$4,200
Save 3,000
Per Person
View Trip
11 Day Roman Holiday with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 27 November 2027
Visit: Italy, Corsica, France, Spain, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,949
Oceanview
$3,749
Balcony
$4,399
Suite
$6,399
From
US$2,949
Save 2,949
Per Person
View Trip
8 Day Greece, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia
Value Fare
Inside
$1,409
Oceanview
$1,609
Balcony
$1,909
Suite
$4,059
From
US$1,409
Per Person
View Trip
12 Day Legendary Mediterranean with Oceania Cruises
Cruise
 (2)

12 Days (11 Nights) Lisbon to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 24 June 2026
Visit: Portugal, Spain, France, Italy, Greece
Your World Inclusions
Exclusive Savings
Inside
$2,975
Oceanview
$3,185
Balcony
$4,900
Suite
$6,020
From
US$2,975
Save 5,523
Per Person
View Trip
11 Day Spain Intensive Cruise: Seville, Malaga & Valencia with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 13 September 2028
Visit: Portugal, Spain, Gibraltar
Azamara Always Included
Inside
$2,519
Oceanview
$2,739
Balcony
$3,369
Suite
$4,759
From
US$2,519
Per Person
View Trip
11 Day Lisbon to Civitavecchia (Rome) with Silversea
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 06 April 2027
Visit: Portugal, Spain, France, Italy
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,200
Suite
$12,000
From
US$7,200
Save 2,500
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 28 May 2027
Visit: Italy, Malta, Montenegro, Croatia, Sicily, Spain, Corsica
Bonus Onboard Credit
Value Fare
Inside
$3,609
Oceanview
$3,959
Balcony
$4,829
Suite
$9,759
From
US$3,609
Per Person
View Trip
11 Day New Year's Mediterranean & Morocco Cruise: Malaga, Seville & Lisbon with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 29 December 2026
Visit: Spain, Morocco, Portugal
Azamara Always Included
Inside
$2,249
Oceanview
$2,649
Balcony
$3,099
Suite
$5,009
From
US$2,249
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Visit: Spain, Corsica, Italy, Malta, Montenegro, Croatia
Bonus Onboard Credit
Value Fare
Inside
$2,139
Oceanview
$2,459
Balcony
$2,779
Suite
$5,869
From
US$2,139
Per Person
View Trip
15 Day Italy, Spain And Adriatic with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Visit: Spain, Sardinia, Sicily, Italy, Greece, Montenegro, Croatia
Inside
$2,389
Oceanview
$2,529
Balcony
$3,589
Suite
$5,369
From
US$2,389
Per Person
View Trip
11 Day Italian & Iberian Radiance with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 01 June 2026
Visit: Spain, France, Italy, Portugal
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$6,349
Balcony
-
Suite
-
From
US$6,349
Save 6,349
Per Person
View Trip
10 Day Italy Intensive Cruise: Portovenere, Florence & Elba Island with Azamara Cruises
Cruise
 (5)

10 Days (9 Nights) Nice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 30 September 2028
Visit: France, Italy, Sardinia
Azamara Always Included
Inside
$2,239
Oceanview
$2,449
Balcony
$3,009
Suite
$4,259
From
US$2,239
Per Person
View Trip
30 Day Italy, Spain & France Combination Cruise: Florence, Seville & Bordeaux with Azamara Cruises
Cruise
 (5)

30 Days (29 Nights) Barcelona to London
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 21 April 2028
Visit: Spain, France, Monaco, Italy (+4 more), Sardinia, Gibraltar, Portugal, England
Azamara Always Included
Inside
$6,759
Oceanview
$7,309
Balcony
$8,959
Suite
$12,589
From
US$6,759
Per Person
View Trip
8 Day Spain Intensive: Malaga, Valencia & Barcelona with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Malaga to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 February 2027
Visit: Spain, Morocco
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$1,739
Oceanview
$1,999
Balcony
$2,279
Suite
$3,649
From
US$1,739
Per Person
View Trip
22 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy, Croatia
Value Fare
Inside
$3,899
Oceanview
$4,249
Balcony
$5,549
Suite
$11,649
From
US$3,899
Per Person
View Trip
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