Home > Cruises > Europe Cruises > Mediterranean Cruises > Luxury Cruises

Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 715 unique cruise itineraries with 1209 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 810 departures starting between March 2026 and November 2028.
Filter Results
Departures
Show More...
Duration
5 Days
50 Days
Start & End Cities
Ship Size
Cruise Lines
Show More...
Price
$1,000pp
$139,998pp
Countries
Show More...
Filter Results
715 Cruises (810 Cruise Departures)
10 Day Italian Shores and Isle of Beauty with Ponant
Cruise
 (2)

10 Days (9 Nights) Valletta to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 June 2027
Visit: Malta, Sicily, Italy, Corsica, France
Inside
-
Oceanview
$7,090
Balcony
$7,470
Suite
$13,900
From
US$7,090
Per Person
View Trip
7 Day A Journey From The Eternal City To Catalan Shores with Explora Journeys
Cruise

7 Days (6 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 09 June 2026
Visit: Italy, Sicily, Malta, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,130
From
US$5,130
Per Person
View Trip
11 Day Romantic Mediterranean with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Valletta to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 20 September 2026
Visit: Malta, Sicily, Italy, Sardinia, France, Spain
Your World Inclusions
Exclusive Savings
Inside
$2,784
Oceanview
$2,908
Balcony
$5,259
Suite
$6,908
From
US$2,784
Save 3,914
Per Person
View Trip
15 Day Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 August 2026
Visit: Italy, Spain, France, Sardinia, Sicily
Inside
$2,859
Oceanview
$3,159
Balcony
$3,669
Suite
$7,817
From
US$2,859
Per Person
View Trip
11 Day Hidden Gems of the Western Mediterranean with Ponant
Cruise
 (1)

11 Days (10 Nights) Nice to Barcelona
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 21 June 2027
Visit: France, Italy, Corsica, Spain
Inside
-
Oceanview
-
Balcony
$7,650
Suite
$14,170
From
US$7,650
Per Person
View Trip
9 Day Isle of Beauty & Italian Shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 August 2026
Visit: France, Corsica, Italy
Inside
-
Oceanview
-
Balcony
$6,860
Suite
$14,230
From
US$6,860
Per Person
View Trip
20 Day Central Mediterranean with Cunard
Cruise
 (1)

20 Days (19 Nights) London to London
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 05 September 2027
Visit: England, Portugal, Sardinia, Greece, Croatia, Malta, Spain
Bonus Onboard Credit
Inside
$4,079
Oceanview
$4,329
Balcony
$6,224
Suite
$14,045
From
US$4,079
Per Person
View Trip
11 Day Lisbon to Civitavecchia (Rome) with Silversea
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 06 April 2027
Visit: Portugal, Spain, France, Italy
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$8,800
Suite
$13,600
From
US$8,800
Per Person
View Trip
6 Day A Mediterranean Prelude To Explora III with Explora Journeys
New ReleaseCruise

6 Days (5 Nights) Genoa to Rome
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 24 July 2026
Visit: Italy, France
Inside
-
Oceanview
-
Balcony
-
Suite
$8,150
From
US$8,150
Per Person
View Trip
11 Day Isle of Beauty, Italian Shores & Malta with Ponant
Cruise

11 Days (10 Nights) Nice to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 19 August 2026
Visit: France, Corsica, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$8,950
Suite
$16,710
From
US$8,950
Per Person
View Trip
10 Day Spain Intensive Cruise: Seville, Malaga & Barcelona with Azamara Cruises
Cruise
 (3)

10 Days (9 Nights) Lisbon to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 20 September 2027
Visit: Portugal, Spain, Gibraltar
Azamara Always Included
Exclusive Savings
Inside
$4,312
Oceanview
$4,807
Balcony
$6,107
Suite
$9,056
From
US$4,312
Save 107
Per Person
View Trip
8 Day Relaxing Rivieras with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 06 August 2027
Visit: Spain, France, Italy, Corsica
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,368
Suite
$5,405
From
US$3,368
Save 3,530
Per Person
View Trip
8 Day The French Riviera Under Le Ponant’s Sails with Ponant
Cruise

8 Days (7 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departures: May 2026 to May 2027
Visit: France, Italy
Inside
-
Oceanview
$10,020
Balcony
$16,130
Suite
$17,960
From
US$10,020
Per Person
View Trip
17 Day Riviera Yacht Harbors Of France & Spain with Seabourn
Cruise

17 Days (16 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 November 2028
Visit: Italy, Monaco, France, Spain, Morocco, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,765
Suite
$14,322
From
US$8,765
Save 144
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2026 to Jun 2026
Visit: Spain, France, Italy
Inside
$1,259
Oceanview
$1,239
Balcony
$1,439
Suite
$2,459
From
US$1,239
Per Person
View Trip
16 Day Athens to Lisbon with Silversea
Cruise

16 Days (15 Nights) Athens to Lisbon
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 07 November 2026
Visit: Greece, Malta, Sicily, Tunisia, Sardinia, Spain, Portugal
All-Inclusive Fare
Inside
-
Oceanview
$11,700
Balcony
$12,700
Suite
$12,000
From
US$11,700
Per Person
View Trip
11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2027
Visit: Italy, France, Spain, Portugal
Your World Inclusions
Exclusive Savings
Inside
$1,755
Oceanview
$1,950
Balcony
$3,083
Suite
$4,238
From
US$1,755
Save 3,643
Per Person
View Trip
10 Day Barcelona to Barcelona with Silversea
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 25 October 2027
Visit: Spain, France
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,900
Suite
$10,400
From
US$5,900
Save 2,500
Per Person
View Trip
6 Day Corsica and the French Riviera with Ponant
Cruise
 (1)

6 Days (5 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 20 May 2026
Visit: France, Monaco, Corsica
Inside
-
Oceanview
-
Balcony
$4,240
Suite
$7,890
From
US$4,240
Per Person
View Trip
11 Day Lisbon to Rome with Silversea
Cruise
 (1)

11 Days (10 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 14 June 2026
Visit: Portugal, Spain, France, Monaco, Italy
Last Minute Fare
All-Inclusive Plus Fare
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$6,750
Suite
$13,800
From
US$6,750
Per Person
View Trip
10 Day Nice to Nice with Silversea
Cruise

10 Days (9 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 06 July 2027
Visit: France, Italy, Sicily, Malta
All-Inclusive Fare
Inside
-
Oceanview
$7,900
Balcony
$8,600
Suite
$11,900
From
US$7,900
Per Person
View Trip
9 Day Authentic Mediterranean Shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 06 June 2027
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
$6,300
Balcony
$6,630
Suite
$12,350
From
US$6,300
Per Person
View Trip
12 Day Spain & Italy Cruise: Barcelona, Salerno & Rome with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 20 February 2027
Visit: Spain, Sardinia, Tunisia, Malta, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$3,129
Oceanview
$3,653
Balcony
$4,186
Suite
$6,495
From
US$3,129
Save 70
Per Person
View Trip
11 Day Roman Holiday with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 27 November 2027
Visit: Italy, Corsica, France, Spain, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,741
Oceanview
$3,565
Balcony
$4,293
Suite
$6,233
From
US$2,741
Save 2,857
Per Person
View Trip
22 Day Mediterranean Mosaic: Croatia, Greece & Ephesus with Seabourn
Cruise

22 Days (21 Nights) Rome to Istanbul
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 08 May 2027
Visit: Italy, Sicily, Malta, Croatia, Montenegro, Greece, Turkey
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,696
Suite
-
From
US$21,696
Save 403
Per Person
View Trip
8 Day Greece & Italy Cruise: Olympia, Catania & Amalfi Coast (salerno) with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 26 February 2028
Visit: Greece, Sicily, Italy
Azamara Always Included
Inside
$1,539
Oceanview
$1,949
Balcony
$2,489
Suite
$3,779
From
US$1,539
Per Person
View Trip
6 Day Grand Prix Weekend Cruise: Barcelona, Saint Tropez & Nice with Azamara Cruises
Cruise
 (8)

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 03 June 2027
Visit: Spain, France
Azamara Always Included
Inside
$2,109
Oceanview
$2,289
Balcony
$2,707
Suite
$3,881
From
US$2,109
Per Person
View Trip
12 Day Italy Intensive Cruise: Florence, Sorrento & Sicily with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 September 2027
Visit: France, Italy, Sicily, Montenegro
Azamara Always Included
Exclusive Savings
Inside
$5,445
Oceanview
$6,085
Balcony
$7,317
Suite
$10,489
From
US$5,445
Save 144
Per Person
View Trip
16 Day Mediterranean Pilgrimage with Regent Seven Seas
Cruise

16 Days (15 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 20 November 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, France
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,845
Suite
$15,707
From
US$13,845
Save 14,353
Per Person
View Trip
8 Day Under Sail from Sicily to the Riviera with Ponant
Cruise

8 Days (7 Nights) Palermo to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departure: 24 August 2027
Visit: Sicily, Italy, France
Inside
-
Oceanview
$10,810
Balcony
$17,240
Suite
$19,850
From
US$10,810
Per Person
View Trip
Results: 271-300 of 715

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Luxury Cruises Short Cruise Breaks

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations