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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 605 unique cruise itineraries with 2 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 652 departures starting between February 2026 and October 2028.
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605 Cruises (652 Cruise Departures)
9 Day Knights & Sunsets with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 20 November 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,894
Suite
$7,070
From
US$5,894
Save 11,104
Per Person
View Trip
11 Day Moonlight Over The Mediterranean with Regent Seven Seas
Cruise

11 Days (10 Nights) Venice to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 19 July 2027
Visit: Italy, Croatia, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,040
Suite
$10,069
From
US$9,040
Save 15,358
Per Person
View Trip
29 Day Mediterranean Medley: Italy, Greece & Ephesus with Seabourn
Cruise

29 Days (28 Nights) Rome to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 08 May 2027
Visit: Italy, Sicily, Malta, Croatia, Montenegro, Greece, Turkey
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,292
Suite
-
From
US$21,292
Save 382
Per Person
View Trip
9 Day Andalusia to Catalonia with Emerald Cruises
New ReleaseCruise

9 Days (8 Nights) Malaga to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 24 April 2027
Visit: Spain, Gibraltar, Morocco
Wave Offer
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$6,304
Balcony
-
Suite
$8,729
From
US$6,304
Save 9,486
Per Person
View Trip
11 Day Jewels of the Mediterranean with Scenic
New ReleaseCruise

11 Days (10 Nights) Palma de Mallorca to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 May 2027
Visit: Spain, Sardinia, Sicily, Malta
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,731
Suite
$17,637
From
US$9,731
Save 17,259
Per Person
View Trip
9 Day Barcelona to Monte Carlo with Silversea
Cruise

9 Days (8 Nights) Barcelona to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 June 2026
Visit: Spain, France, Monaco
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,700
Suite
$8,440
From
US$5,700
Save 3,800
Per Person
View Trip
8 Day European Yearnings with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 02 July 2027
Visit: Italy, Monaco, France, Spain
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,981
Suite
$4,776
From
US$2,981
Save 3,117
Per Person
View Trip
9 Day Splendours of Sicily, Italy and the French Riviera with Scenic
New ReleaseCruise

9 Days (8 Nights) Valletta to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 13 May 2027
Visit: Malta, Sicily, Italy, Corsica, France, Monaco
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,991
Suite
$14,453
From
US$9,991
Save 13,599
Per Person
View Trip
8 Day Yachting Gems of the French and Italian Rivieras with Emerald Cruises
New ReleaseCruise

8 Days (7 Nights) Barcelona to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 14 August 2027
Visit: Spain, France, Corsica, Italy
Wave Offer
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$5,652
Balcony
-
Suite
$7,762
From
US$5,652
Save 8,338
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 20 April 2026
Visit: France, Corsica, Sardinia, Spain
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
$5,550
Balcony
$6,350
Suite
$12,480
From
US$5,550
Per Person
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 October 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,790
Suite
$9,660
From
US$6,790
Save 2,910
Per Person
View Trip
12 Day Barcelona to Barcelona with Silversea
Cruise

12 Days (11 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 April 2026
Visit: Spain, France, Gibraltar
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$5,550
Suite
$9,370
From
US$5,550
Per Person
View Trip
9 Day Barcelona to Civitavecchia (Rome) with Silversea
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 21 May 2027
Visit: Spain, Sardinia, Sicily, Malta, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,530
Suite
$8,110
From
US$5,530
Save 2,370
Per Person
View Trip
22 Day Ultimate Italy, French Riviera & the Mediterranean Islands with Scenic
New ReleaseCruise

22 Days (21 Nights) Rome to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 27 June 2028
Visit: Italy, Monaco, France, Spain, Corsica, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$63,497
Suite
$73,488
From
US$63,497
Save 1,883
Per Person
View Trip
6 Day Malaga to Nice with Silversea
Cruise

6 Days (5 Nights) Malaga to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 22 March 2026
Visit: Spain, France
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$4,020
Balcony
$4,500
Suite
$6,900
From
US$4,020
Save 2,680
Per Person
View Trip
10 Day Under The Tuscan Sunset with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 17 June 2027
Visit: Spain, Corsica, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,837
Suite
$9,033
From
US$8,837
Save 14,161
Per Person
View Trip
22 Day Mediterranean Mosaic: Croatia, Italy, France & Spain with Seabourn
Cruise

22 Days (21 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy (+5 more), Monaco, France, Spain, Corsica, Sardinia
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,121
Suite
$25,467
From
US$14,121
Save 243
Per Person
View Trip
9 Day Italy, France & Tunisia with Seabourn
Cruise

9 Days (8 Nights) Genoa to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 April 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,480
Suite
$9,428
From
US$5,480
Save 95
Per Person
View Trip
9 Day Ancient Cities of the Mediterranean with Ponant
Cruise

9 Days (8 Nights) Athens to Valletta
Cruise Line: Ponant
Ships: Le Champlain, Le Dumont d’Urville
Departures: Nov 2026 to Oct 2027
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$7,110
Suite
$12,620
From
US$7,110
Per Person
View Trip
9 Day Corsica, Sardinia & Iberian Shores with Ponant
Cruise

9 Days (8 Nights) Nice to Barcelona
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 03 August 2026
Visit: France, Corsica, Sardinia, Spain
Inside
-
Oceanview
-
Balcony
$8,740
Suite
$15,620
From
US$8,740
Per Person
View Trip
13 Day Mediterranean Nights with Regent Seven Seas
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 28 September 2026
Visit: Spain, France, Italy, Malta
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,046
Suite
$13,202
From
US$11,046
Save 16,852
Per Person
View Trip
6 Day Côte d'Azur & Beyond with Emerald Cruises
New ReleaseCruise

6 Days (5 Nights) Nice to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 21 May 2026
Visit: France, Italy, Monaco
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,541
From
US$11,541
Save 16,249
Per Person
View Trip
7 Day Rome to Monte Carlo with Silversea
Cruise

7 Days (6 Nights) Rome to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 09 August 2026
Visit: Italy, France, Monaco
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,020
Suite
$5,040
From
US$4,020
Save 2,680
Per Person
View Trip
13 Day Iberian & Italian Autumn with Oceania Cruises
Cruise

13 Days (12 Nights) Lisbon to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 25 September 2027
Visit: Portugal, Spain, France, Italy, Sicily, Greece
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,098
Suite
$8,669
From
US$6,098
Save 6,400
Per Person
View Trip
10 Day Caesars & Conquistadors with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 15 June 2027
Visit: Italy, Monaco, Spain, Gibraltar, Portugal
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,196
Suite
$6,427
From
US$4,196
Save 4,402
Per Person
View Trip
8 Day Riviera Radiance with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 22 October 2027
Visit: Italy, France, Spain
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,543
Suite
$4,483
From
US$2,543
Save 2,655
Per Person
View Trip
11 Day Barcelona to Rome with Silversea
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 05 March 2026
Visit: Spain, France, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,280
Suite
$19,570
From
US$5,280
Save 3,520
Per Person
View Trip
10 Day Lisbon to Nice with Silversea
Cruise

10 Days (9 Nights) Lisbon to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 23 March 2027
Visit: Portugal, Spain, France
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$4,550
Balcony
$5,460
Suite
$11,000
From
US$4,550
Save 1,950
Per Person
View Trip
11 Day Pearls of Southern Spain & Portugal with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 28 September 2026
Visit: Spain, Morocco, Portugal
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$10,313
From
US$10,313
Save 12,877
Per Person
View Trip
9 Day Monte Carlo to Civitavecchia (Rome) with Silversea
Cruise

9 Days (8 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 11 September 2027
Visit: Monaco, France, Sardinia, Corsica, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,090
Suite
$10,880
From
US$6,090
Save 2,610
Per Person
View Trip
Results: 271-300 of 605

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