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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 715 unique cruise itineraries with 1209 past traveler reviews from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise sailing in and around the Mediterranean with 810 departures starting between March 2026 and November 2028.
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715 Cruises (810 Cruise Departures)
8 Day Western Mediterranean Cruise: Italy, France & Spain with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departures: Oct 2026 to Oct 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$2,167
Oceanview
$2,749
Balcony
$3,079
Suite
$6,134
From
US$2,167
Save 81
Per Person
View Trip
9 Day Barcelona to Barcelona with Silversea
Cruise

9 Days (8 Nights) Barcelona to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 24 April 2027
Visit: Spain
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$8,000
Suite
$12,200
From
US$8,000
Per Person
View Trip
10 Day Ancient Shores of the Mediterranean with Ponant
Cruise

10 Days (9 Nights) Valletta to Malaga
Cruise Line: Ponant
Ships: Le Bougainville, Le Champlain (+2 more), Le Dumont d’Urville, Le Laperouse
Departures: Oct 2026 to Nov 2027
Visit: Malta, Sicily, Tunisia, Algeria, Spain
Inside
-
Oceanview
-
Balcony
$7,320
Suite
$13,610
From
US$7,320
Per Person
View Trip
16 Day Barcelona to Civitavecchia with Silversea
Cruise

16 Days (15 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 25 July 2026
Visit: Spain, Corsica, France, Monaco, Italy
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$7,500
Suite
$11,800
From
US$7,500
Per Person
View Trip
11 Day Mediterranean Medley with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 02 July 2026
Visit: Italy, Sicily, Malta, Spain, France, Monaco
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$2,387
Balcony
$4,131
Suite
$5,183
From
US$2,387
Save 5,111
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Nice & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 December 2027
Visit: Italy, France, Spain
Azamara Always Included
Inside
$1,609
Oceanview
$2,029
Balcony
$2,569
Suite
$3,859
From
US$1,609
Per Person
View Trip
8 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 November 2027
Visit: Italy, France, Spain
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$6,900
Suite
$10,100
From
US$6,900
Per Person
View Trip
8 Day A Journey Of Antique Treasures To Sumptuous Catalan with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 07 September 2026
Visit: Italy, Monaco, France, Spain
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$5,320
From
US$5,320
Per Person
View Trip
8 Day Regards From The Riviera with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 September 2027
Visit: Italy, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,099
Oceanview
$2,249
Balcony
$3,416
Suite
$4,774
From
US$2,099
Save 2,099
Per Person
View Trip
10 Day A Journey Of Golden Coastlines & Ancient Wonders with Explora Journeys
Cruise
 (1)

10 Days (9 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 April 2026
Visit: Spain, Monaco, Italy, Greece
Inside
-
Oceanview
-
Balcony
-
Suite
$6,720
From
US$6,720
Per Person
View Trip
10 Day A Journey Through The Marvels Of The Mediterranean & Spirited Modern Cities with Explora Journeys
Cruise

10 Days (9 Nights) Athens to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 April 2026
Visit: Greece, Sicily, Malta, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,660
From
US$5,660
Per Person
View Trip
9 Day Monte Carlo to Civitavecchia (Rome) with Silversea
Cruise

9 Days (8 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 11 September 2027
Visit: Monaco, France, Sardinia, Corsica, Italy
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,100
Suite
$11,400
From
US$7,100
Save 2,500
Per Person
View Trip
9 Day Spanish & French Coastal Charm with Seabourn
Cruise

9 Days (8 Nights) Barcelona to Monte Carlo
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 15 July 2027
Visit: Spain, France, Monaco
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,835
Suite
$13,735
From
US$8,835
Save 164
Per Person
View Trip
15 Day Rome to Lisbon with Silversea
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Visit: Italy, Malta, Sicily, Tunisia, Sardinia, Spain, Portugal
All-Inclusive Fare
Inside
-
Oceanview
$9,500
Balcony
$10,200
Suite
$17,600
From
US$9,500
Per Person
View Trip
21 Day Summer Splendor with Oceania Cruises
Cruise
 (1)

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 June 2027
Visit: Italy, Sicily, Sardinia, Corsica (+5 more), France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$5,922
Oceanview
$6,456
Balcony
$10,433
Suite
$14,070
From
US$5,922
Save 6,176
Per Person
View Trip
8 Day Yachting Gems of the French and Italian Rivieras with Emerald Cruises
New ReleaseCruise

8 Days (7 Nights) Barcelona to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 14 August 2027
Visit: Spain, France, Corsica, Italy
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
$5,893
Balcony
-
Suite
$7,787
From
US$5,893
Save 752
Per Person
View Trip
15 Day Croatia, Montenegro, Italy, Monaco & France with Seabourn
Cruise

15 Days (14 Nights) Dubrovnik to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy, Monaco, France, Spain
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,455
Suite
$19,923
From
US$13,455
Save 244
Per Person
View Trip
12 Day Heavenly Islands & Iberian Shores with Ponant
Cruise

12 Days (11 Nights) Barcelona to Porto
Cruise Line: Ponant
Ship: Le Champlain
Departure: 06 May 2026
Visit: Spain, Portugal
Inside
-
Oceanview
-
Balcony
$11,440
Suite
$21,490
From
US$11,440
Per Person
View Trip
9 Day 2026 Grand Prix Cruise: Nice, Portofino & Florence with Azamara Cruises
Cruise
 (3)

9 Days (8 Nights) Nice to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 02 June 2026
Visit: France, Italy, Spain
Azamara Always Included
Inside
$1,749
Oceanview
$1,889
Balcony
$2,269
Suite
-
From
US$1,749
Per Person
View Trip
8 Day Rome to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$6,200
Suite
$9,200
From
US$6,200
Per Person
View Trip
8 Day Spain & Portugal Cruise: Barcelona, Seville & Lisbon with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 22 May 2027
Visit: Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$2,279
Oceanview
$2,540
Balcony
$3,307
Suite
$5,237
From
US$2,279
Per Person
View Trip
9 Day Epicurean Delights: The Food & Wine of Sicily with Ponant
Cruise

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 11 April 2026
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$12,160
Suite
$19,420
From
US$12,160
Per Person
View Trip
5 Day A Journey Through Legendary Crossroads & Island Spirit with Explora Journeys
Cruise

5 Days (4 Nights) Valletta to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 29 April 2026
Visit: Malta, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$2,510
From
US$2,510
Per Person
View Trip
13 Day Best Of The Mediterranean Cruise: Crete, Sicily, Corsica & Majorca with Azamara Cruises
Cruise
 (3)

13 Days (12 Nights) Athens to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 19 October 2027
Visit: Greece, Sicily, Malta, Tunisia (+4 more), Sardinia, France, Corsica, Spain
Azamara Always Included
Exclusive Savings
Inside
$4,517
Oceanview
$4,963
Balcony
$5,953
Suite
$8,378
From
US$4,517
Save 112
Per Person
View Trip
8 Day Grecian & Roman Gems with Seabourn
Cruise
 (1)

8 Days (7 Nights) Athens to Rome
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 25 October 2026
Visit: Greece, Albania, Italy
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
$6,398
Balcony
$9,128
Suite
$13,538
From
US$6,398
Save 116
Per Person
View Trip
17 Day France, Italy, Tunisia, Monaco & Spain with Seabourn
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2027
Visit: Italy, Corsica, Sardinia, Tunisia (+4 more), Sicily, Monaco, France, Spain
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,454
Suite
$19,922
From
US$13,454
Save 245
Per Person
View Trip
9 Day Mediterranean Sunrise with Oceania Cruises
Cruise
 (1)

9 Days (8 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 03 March 2027
Visit: Portugal, Spain, France, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$1,920
Oceanview
$2,120
Balcony
$3,431
Suite
$4,740
From
US$1,920
Save 2,878
Per Person
View Trip
15 Day Iberia & Italian Treasures with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 21 December 2026
Visit: Portugal, Spain, France, Italy, Corsica
Your World Inclusions
Exclusive Savings
Inside
$2,869
Oceanview
$3,152
Balcony
$5,415
Suite
$7,307
From
US$2,869
Save 6,129
Per Person
View Trip
18 Day Mediterranean & Egypt Cruise: Italy, Greece & Malta with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 December 2026
Visit: Italy, Sicily, Greece, Egypt, Malta
Azamara Always Included
Exclusive Savings
Inside
$4,174
Oceanview
$4,785
Balcony
$5,542
Suite
$8,578
From
US$4,174
Save 85
Per Person
View Trip
13 Day Passage To Portugal with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Monte Carlo to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 12 July 2026
Visit: Monaco, France, Spain, Gibraltar, Morocco, Portugal
Your World Inclusions
Exclusive Savings
Inside
$2,600
Oceanview
$2,803
Balcony
$5,230
Suite
$6,577
From
US$2,600
Save 5,398
Per Person
View Trip
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