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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
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780 Cruises (900 Cruise Departures)
12 Day Mediterranean Rivieras with Emerald Cruises
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 27 October 2026
Visit: Italy, Corsica, Spain, Morocco, Portugal
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$7,790
Balcony
-
Suite
$10,711
From
US$7,790
Save 1,855
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 July 2028
Visit: Italy, Spain, France, Corsica (+5 more), Malta, Montenegro, Croatia, Greece, Sicily
Cunard Fare
Value Fare
Inside
$4,364
Oceanview
$4,859
Balcony
$5,939
Suite
$10,169
From
US$4,364
Per Person
View Trip
19 Day An Extended Journey Across The Mediterranean’s Western Shores with Explora Journeys
Cruise
 (1)

19 Days (18 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 24 January 2027
Visit: Spain, France, Italy, Sicily, Tunisia, Algeria
Inside
-
Oceanview
-
Balcony
-
Suite
$8,580
From
US$8,580
Per Person
View Trip
9 Day Isle of Beauty & Italian shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 August 2026
Visit: France, Corsica, Italy
Inside
-
Oceanview
$6,520
Balcony
$7,220
Suite
$14,580
From
US$6,520
Per Person
View Trip
29 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise
 (1)

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy, France, Greece, Turkey
Inside
$5,619
Oceanview
$5,619
Balcony
$6,819
Suite
-
From
US$5,619
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Nice & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 December 2027
Visit: Italy, France, Spain
Azamara Always Included
Inside
$1,609
Oceanview
$2,029
Balcony
$2,629
Suite
$3,959
From
US$1,609
Per Person
View Trip
8 Day Italy And France with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 24 September 2027
Visit: Italy, France, Corsica, Spain
Bonus Onboard Credit
Value Fare
Inside
$1,239
Oceanview
$1,289
Balcony
$1,429
Suite
$3,029
From
US$1,239
Per Person
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 September 2026
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Value Fare
Inside
$1,229
Oceanview
$1,329
Balcony
$1,529
Suite
$5,549
From
US$1,229
Per Person
View Trip
22 Day Spain & Italy Combination Cruise: Seville, Valencia & Florence with Azamara Cruises
Cruise
 (3)

22 Days (21 Nights) Lisbon to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 March 2028
Visit: Portugal, Spain, Morocco, Gibraltar, France, Monaco, Italy
Azamara Always Included
Inside
$5,019
Oceanview
$5,409
Balcony
$6,639
Suite
$9,299
From
US$5,019
Per Person
View Trip
22 Day Italy, Croatia & Greece Combination Cruise: Sorrento, Dubrovnik & Athens with Azamara Cruises
Cruise
 (3)

22 Days (21 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 April 2028
Visit: Italy, Sicily, Montenegro, Slovenia, Croatia, Greece
Azamara Always Included
Inside
$5,319
Oceanview
$5,759
Balcony
$7,059
Suite
$9,939
From
US$5,319
Per Person
View Trip
10 Day A Journey Through Southern European Elegance & Renaissance Treasures with Explora Journeys
Cruise
 (1)

10 Days (9 Nights) Barcelona to Monte Carlo
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 22 May 2028
Visit: Spain, Italy, France, Corsica, Monaco
Inside
-
Oceanview
-
Balcony
-
Suite
$5,915
From
US$5,915
Per Person
View Trip
13 Day Civitavecchia (Rome) to Lisbon with Silversea
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Nova
Departure: 21 November 2027
Visit: Italy, France, Spain, Morocco, Portugal
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,700
Suite
$10,400
From
US$6,700
Save 3,000
Per Person
View Trip
11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2027
Visit: Italy, France, Spain, Portugal
Your World Inclusions
Exclusive Savings
Inside
$1,995
Oceanview
$2,205
Balcony
$3,290
Suite
$4,550
From
US$1,995
Save 3,703
Per Person
View Trip
8 Day Italy, Malta And Adriatic with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 September 2028
Visit: Italy, Malta, Croatia
Cunard Fare
Value Fare
Inside
$1,674
Oceanview
$1,899
Balcony
$2,349
Suite
$4,284
From
US$1,674
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 July 2026
Visit: Italy, France, Corsica, Spain
Inside
$699
Oceanview
$799
Balcony
$999
Suite
$2,199
From
US$699
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 September 2028
Visit: Italy, Malta, Croatia, Greece (+4 more), Sicily, Spain, France, Corsica
Cunard Fare
Value Fare
Inside
$4,409
Oceanview
$4,769
Balcony
$5,939
Suite
$10,169
From
US$4,409
Per Person
View Trip
12 Day Italy Intensive Cruise: Rome, Amalfi & Venice with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 August 2026
Visit: Italy, Sicily, Montenegro
Azamara Always Included
Inside
$2,419
Oceanview
$2,849
Balcony
-
Suite
-
From
US$2,419
Per Person
View Trip
10 Day Mysteries Of History with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 24 May 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,699
Oceanview
$2,949
Balcony
$4,499
Suite
$6,399
From
US$2,699
Save 2,699
Per Person
View Trip
26 Day Greece, Italy & France Combination Cruise: Alexandria, Athens & Nice with Azamara Cruises
Cruise
 (3)

26 Days (25 Nights) Athens to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 February 2028
Visit: Greece, Egypt, Cyprus, Turkey (+4 more), Sicily, Italy, France, Spain
Azamara Always Included
Inside
$7,049
Oceanview
$8,529
Balcony
$10,559
Suite
$15,319
From
US$7,049
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2027 to Sep 2027
Visit: Italy, Corsica, Spain, Malta, Montenegro, Croatia
Bonus Onboard Credit
Value Fare
Inside
$1,939
Oceanview
$2,179
Balcony
$2,409
Suite
$5,289
From
US$1,939
Per Person
View Trip
15 Day Iberian Peninsula Cruise: Portugal & Spain with Azamara Cruises
Cruise
 (8)

15 Days (14 Nights) Lisbon to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 February 2027
Visit: Portugal, Spain, Gibraltar, Morocco
Azamara Always Included
Inside
$3,279
Oceanview
$3,769
Balcony
$4,259
Suite
$6,619
From
US$3,279
Per Person
View Trip
8 Day Spain Intensive Cruise: Barcelona, Valencia & Malaga with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Malaga
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 11 March 2028
Visit: Spain, Gibraltar
Azamara Always Included
Inside
$1,679
Oceanview
$2,089
Balcony
$2,689
Suite
$4,019
From
US$1,679
Per Person
View Trip
12 Day Best Of The Mediterranean Cruise: La Goulette, Valletta & Siracusa with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Athens to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 February 2028
Visit: Greece, Egypt, Cyprus, Turkey
Azamara Always Included
Inside
$3,949
Oceanview
$4,629
Balcony
$5,489
Suite
$7,559
From
US$3,949
Per Person
View Trip
22 Day Mediterranean, Adriatic, Greece And Turkiye with Cunard
Cruise
 (13)

22 Days (21 Nights) Istanbul to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 02 June 2028
Visit: Turkey, Greece, Italy, Malta (+4 more), Montenegro, Croatia, Sicily, Spain
Cunard Fare
Value Fare
Inside
$4,654
Oceanview
$5,149
Balcony
$6,139
Suite
$10,999
From
US$4,654
Per Person
View Trip
11 Day Italy Intensive Cruise: Florence, Sorrento & Venice with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 August 2028
Visit: Italy, Sicily, Montenegro
Azamara Always Included
Inside
$3,389
Oceanview
$3,679
Balcony
$4,519
Suite
$6,379
From
US$3,389
Per Person
View Trip
10 Day Spain Intensive Cruise: Seville, Malaga & Valencia with Azamara Cruises
Cruise
 (3)

10 Days (9 Nights) Lisbon to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 06 September 2028
Visit: Portugal, Spain, Gibraltar
Azamara Always Included
Inside
$2,269
Oceanview
$2,479
Balcony
$3,039
Suite
$4,289
From
US$2,269
Per Person
View Trip
22 Day Italy, Greece And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 20 August 2027
Visit: Spain, Malta, Montenegro, Croatia (+4 more), Italy, Greece, Sicily, Corsica
Bonus Onboard Credit
Value Fare
Inside
$2,899
Oceanview
$3,279
Balcony
$3,819
Suite
$8,139
From
US$2,899
Per Person
View Trip
8 Day Malta, Croatia And Montenegro with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: May 2027 to Aug 2028
Visit: Italy, Malta, Montenegro, Croatia
Bonus Onboard Credit
Cunard Fare
Value Fare
Inside
$1,179
Oceanview
$1,279
Balcony
$1,419
Suite
$2,919
From
US$1,179
Per Person
View Trip
13 Day Springtime Splendor with Oceania Cruises
Cruise
 (3)

13 Days (12 Nights) Barcelona to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 28 April 2027
Visit: Spain, Morocco, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$4,099
Oceanview
-
Balcony
$6,149
Suite
$8,549
From
US$4,099
Save 4,099
Per Person
View Trip
18 Day European Artistry with Oceania Cruises
Cruise
 (1)

18 Days (17 Nights) Lisbon to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 24 July 2026
Visit: Portugal, Spain, Gibraltar, Corsica (+6 more), Italy, Sicily, Greece, Montenegro, Croatia, Slovenia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$6,349
Oceanview
-
Balcony
$9,249
Suite
$20,499
From
US$6,349
Save 6,349
Per Person
View Trip
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