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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 780 unique cruise itineraries with 1760 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 900 departures starting between May 2026 and April 2029.
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780 Cruises (900 Cruise Departures)
10 Day Spain Cruise: Seville, Valencia & Malaga with Azamara Cruises
Cruise
 (3)

10 Days (9 Nights) Barcelona to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 06 June 2028
Visit: Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$3,069
Oceanview
$3,319
Balcony
$4,089
Suite
$5,799
From
US$3,069
Per Person
View Trip
15 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 22 June 2026
Visit: Spain, Sardinia, Corsica, Sicily (+4 more), Italy, Greece, Montenegro, Croatia
Cunard Fare
Inside
$2,119
Oceanview
$2,299
Balcony
$2,629
Suite
-
From
US$2,119
Per Person
View Trip
10 Day Best Of The Mediterranean Cruise: La Goulette, Valletta & Siracusa with Azamara Cruises
Cruise
 (3)

10 Days (9 Nights) Malaga to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 29 January 2028
Visit: Spain, Algeria, Tunisia, Malta, Sicily, Greece
Azamara Always Included
Inside
$2,609
Oceanview
$3,089
Balcony
$3,879
Suite
$5,549
From
US$2,609
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 03 September 2027
Visit: Italy, Corsica, Spain, Malta (+4 more), Montenegro, Croatia, Greece, Sicily
Bonus Onboard Credit
Value Fare
Inside
$3,089
Oceanview
$3,479
Balcony
$4,349
Suite
$8,339
From
US$3,089
Per Person
View Trip
8 Day Mediterranean Holiday with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 06 October 2026
Visit: Spain, France, Italy, Corsica, Sardinia, Sicily
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,899
Oceanview
$3,199
Balcony
$4,299
Suite
$5,399
From
US$2,899
Save 2,899
Per Person
View Trip
12 Day Spain & Italy Cruise: Barcelona, Salerno & Rome with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 20 February 2027
Visit: Spain, Sardinia, Tunisia, Malta, Sicily, Italy
Azamara Always Included
Inside
$2,819
Oceanview
$3,289
Balcony
$3,769
Suite
$5,839
From
US$2,819
Per Person
View Trip
8 Day Malta, Croatia And Montenegro with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2027 to Sep 2027
Visit: Spain, Malta, Montenegro, Croatia, Italy
Bonus Onboard Credit
Value Fare
Inside
$1,139
Oceanview
$1,189
Balcony
$1,419
Suite
$2,829
From
US$1,139
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Nice & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 December 2027
Visit: Italy, France, Spain
Azamara Always Included
Inside
$1,609
Oceanview
$2,029
Balcony
$2,629
Suite
$3,959
From
US$1,609
Per Person
View Trip
8 Day Italy, Greece And Turkey with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 May 2027
Visit: Spain, Sicily, Greece, Turkey
Bonus Onboard Credit
Value Fare
Inside
$1,139
Oceanview
$1,369
Balcony
$1,499
Suite
$3,069
From
US$1,139
Per Person
View Trip
10 Day Seascapes & Gastronomy with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 06 October 2027
Visit: Italy, Sicily, Malta, Greece, Albania, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,499
Oceanview
$2,849
Balcony
$4,399
Suite
$6,199
From
US$2,499
Save 2,499
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 July 2028
Visit: Italy, Spain, France, Corsica (+5 more), Malta, Montenegro, Croatia, Greece, Sicily
Cunard Fare
Value Fare
Inside
$4,364
Oceanview
$4,859
Balcony
$5,939
Suite
$10,169
From
US$4,364
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Jun 2028 to Aug 2028
Visit: Italy, Malta, Montenegro, Croatia, Greece, Sicily, Spain
Cunard Fare
Value Fare
Inside
$2,979
Oceanview
$3,384
Balcony
$4,149
Suite
$7,659
From
US$2,979
Per Person
View Trip
15 Day An Extended Journey From Venetian Canals To Renaissance Island Marvels with Explora Journeys
Cruise
 (1)

15 Days (14 Nights) Venice to Venice
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 August 2027
Visit: Italy, Croatia, Montenegro, Greece, Turkey
Inside
-
Oceanview
-
Balcony
-
Suite
$9,280
From
US$9,280
Per Person
View Trip
19 Day Greece, Egypt & Italy Combination Cruise: Alexandria, Athens & Amalfi Coast with Azamara Cruises
Cruise
 (3)

19 Days (18 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 February 2028
Visit: Greece, Egypt, Cyprus, Turkey, Sicily, Italy
Azamara Always Included
Inside
$5,479
Oceanview
$6,539
Balcony
$8,009
Suite
$11,439
From
US$5,479
Per Person
View Trip
8 Day Croatia, Malta And Montenegro with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 18 June 2027
Visit: Italy, Malta, Montenegro, Croatia
Bonus Onboard Credit
Value Fare
Inside
$1,189
Oceanview
$1,369
Balcony
$1,539
Suite
$8,439
From
US$1,189
Per Person
View Trip
10 Day A Journey From Italian Gems To Spain’s Southern Coast with Explora Journeys
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 05 March 2027
Visit: Italy, France, Corsica, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$4,810
From
US$4,810
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Visit: Spain, Corsica, Italy, Malta, Montenegro, Croatia
Bonus Onboard Credit
Value Fare
Inside
$2,139
Oceanview
$2,459
Balcony
$2,779
Suite
$5,869
From
US$2,139
Per Person
View Trip
8 Day Italy And Adriatic with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Visit: Spain, Italy, Sicily, Greece, Montenegro
Inside
$899
Oceanview
$1,099
Balcony
$2,269
Suite
$3,009
From
US$899
Per Person
View Trip
15 Day Adriatic & Aegean Radiance with Oceania Cruises
Cruise
 (2)

15 Days (14 Nights) Monte Carlo to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 17 July 2026
Visit: Monaco, Sicily, Malta, Croatia, Montenegro, Greece, Turkey
Memorial Day Sale
Your World Inclusions
Exclusive Savings
Inside
$3,710
Oceanview
$3,780
Balcony
$6,055
Suite
$7,805
From
US$3,710
Save 6,888
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 23 July 2027
Visit: Italy, Spain, Sardinia, Corsica (+4 more), Malta, Croatia, Greece, Sicily
Cunard Fare
Value Fare
Inside
$2,909
Oceanview
$3,219
Balcony
$3,779
Suite
$8,339
From
US$2,909
Per Person
View Trip
10 Day Mysteries Of History with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 24 May 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,699
Oceanview
$2,949
Balcony
$4,499
Suite
$6,399
From
US$2,699
Save 2,699
Per Person
View Trip
11 Day Italy, Croatia & France Cruise: Venice, Dubrovnik & Nice with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Venice to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 22 May 2028
Visit: Italy, Croatia, Montenegro, France, Spain
Azamara Always Included
Inside
$2,999
Oceanview
$3,259
Balcony
$4,019
Suite
$5,679
From
US$2,999
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 13 July 2026
Visit: Italy, France, Corsica, Spain
Inside
$1,809
Oceanview
$1,949
Balcony
$2,249
Suite
$4,749
From
US$1,809
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 09 June 2028
Visit: Italy, Malta, Montenegro, Croatia (+4 more), Greece, Sicily, Spain, Corsica
Cunard Fare
Value Fare
Inside
$4,344
Oceanview
$4,839
Balcony
$5,829
Suite
$10,149
From
US$4,344
Per Person
View Trip
11 Day Radiant Rivieras with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 November 2026
Visit: Spain, France, Monaco, Italy
Memorial Day Sale
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,025
Suite
$5,355
From
US$4,025
Save 7,473
Per Person
View Trip
37 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

37 Days (36 Nights) London to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 18 May 2028
Visit: England, Spain, Corsica, Italy (+6 more), Sicily, Greece, Turkey, Malta, Montenegro, Croatia
Cunard Fare
Value Fare
Inside
$7,169
Oceanview
$7,979
Balcony
$9,509
Suite
$16,709
From
US$7,169
Per Person
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 September 2026
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Value Fare
Inside
$1,229
Oceanview
$1,329
Balcony
$1,529
Suite
$5,549
From
US$1,229
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 04 August 2028
Visit: Spain, France, Corsica, Italy
Cunard Fare
Value Fare
Inside
$1,629
Oceanview
$1,764
Balcony
$2,124
Suite
$4,149
From
US$1,629
Per Person
View Trip
16 Day Mediterranean And Greek Islands with Cunard
Cruise
 (13)

16 Days (15 Nights) London to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 18 May 2028
Visit: England, Spain, Corsica, Italy, Sicily, Greece, Turkey
Cunard Fare
Value Fare
Inside
$3,059
Oceanview
$3,374
Balcony
$4,184
Suite
$7,379
From
US$3,059
Per Person
View Trip
22 Day Italy, Greece & Turkey Cruise: Rome, Venice & Athens with Azamara Cruises
Cruise
 (3)

22 Days (21 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 31 October 2027
Visit: Spain, Italy, Sicily, Montenegro (+4 more), Croatia, Greece, Cyprus, Turkey
Azamara Always Included
Inside
$8,389
Oceanview
$10,309
Balcony
$12,609
Suite
$18,409
From
US$8,389
Per Person
View Trip
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