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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 745 unique cruise itineraries with 1204 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 848 departures starting between April 2026 and November 2028.
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745 Cruises (848 Cruise Departures)
8 Day Italy, France & Spain Cruise: Rome, Florence & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 May 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Inside
$2,119
Oceanview
$2,439
Balcony
$3,229
Suite
$5,219
From
US$2,119
Per Person
View Trip
9 Day Greece, Italy & Spain Cruise: Athens, Siracusa & Malaga with Azamara Cruises
Cruise
 (5)

9 Days (8 Nights) Athens to Malaga
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 26 November 2026
Visit: Greece, Sicily, Malta, Tunisia, Spain
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$1,639
Oceanview
$1,969
Balcony
$2,579
Suite
$4,109
From
US$1,639
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 23 July 2027
Visit: Italy, Spain, Sardinia, Corsica, Malta, Croatia
Inside
$1,959
Oceanview
$2,169
Balcony
$2,549
Suite
$5,649
From
US$1,959
Per Person
View Trip
13 Day Best Of The Mediterranean Cruise: Crete, Sicily, Corsica & Majorca with Azamara Cruises
Cruise
 (3)

13 Days (12 Nights) Athens to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 19 October 2027
Visit: Greece, Sicily, Malta, Tunisia (+4 more), Sardinia, France, Corsica, Spain
Azamara Always Included
Inside
$4,629
Oceanview
$5,089
Balcony
$6,109
Suite
-
From
US$4,629
Per Person
View Trip
17 Day Treasures Of Greece & Andalusia with Seabourn
Cruise
 (1)

17 Days (16 Nights) Athens to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 25 October 2026
Visit: Greece, Albania, Italy, Corsica, Sardinia, Spain, Portugal
Yours to Explore
Inside
-
Oceanview
$12,399
Balcony
$16,999
Suite
$25,299
From
US$12,399
Per Person
View Trip
50 Day Lisbon To Barcelona Grand Voyage with Azamara Cruises
Cruise
 (3)

50 Days (49 Nights) Lisbon to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 22 January 2028
Visit: Portugal, Spain, Gibraltar, Algeria (+9 more), Tunisia, Malta, Sicily, Greece, Turkey, Egypt, Cyprus, Italy, France
Azamara Always Included
Inside
$13,739
Oceanview
$16,559
Balcony
$20,459
Suite
$29,559
From
US$13,739
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 15 June 2026
Visit: Spain, France, Italy, Sardinia, Corsica, Sicily
Inside
$2,309
Oceanview
$2,389
Balcony
$3,019
Suite
-
From
US$2,309
Per Person
View Trip
9 Day Wandering the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Athens to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 31 July 2027
Visit: Greece, Sicily, Italy, Corsica, France
Inside
-
Oceanview
-
Balcony
$6,120
Suite
$11,340
From
US$6,120
Per Person
View Trip
22 Day Italy, France, Spain And Adriatic with Cunard
Cruise
 (1)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Visit: Italy, Sicily, Greece, Montenegro (+4 more), Croatia, Malta, Spain, Corsica
Bonus Onboard Credit
Inside
$3,899
Oceanview
$4,119
Balcony
$6,769
Suite
$9,369
From
US$3,899
Per Person
View Trip
26 Day Greece, Italy & France Cruise: Alexandria, Athens & Nice with Azamara Cruises
Cruise
 (3)

26 Days (25 Nights) Athens to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 February 2028
Visit: Greece, Egypt, Cyprus, Turkey (+4 more), Sicily, Italy, France, Spain
Azamara Always Included
Inside
$7,049
Oceanview
$8,529
Balcony
$10,559
Suite
$15,319
From
US$7,049
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Nice & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 December 2027
Visit: Italy, France, Spain
Azamara Always Included
Inside
$1,609
Oceanview
$2,029
Balcony
$2,629
Suite
$3,959
From
US$1,609
Per Person
View Trip
12 Day Best Of The Mediterranean Cruise: La Goulette, Valletta & Siracusa with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Athens to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 February 2028
Visit: Greece, Egypt, Cyprus, Turkey
Azamara Always Included
Inside
$3,949
Oceanview
$4,629
Balcony
$5,489
Suite
$7,559
From
US$3,949
Per Person
View Trip
8 Day Stars Of Spain & Portugal with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 16 June 2026
Visit: Spain, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,299
Oceanview
$2,499
Balcony
$3,799
Suite
$5,199
From
US$2,299
Save 2,299
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 13 July 2026
Visit: Italy, France, Corsica, Spain
Inside
$1,799
Oceanview
$1,949
Balcony
$2,179
Suite
$4,749
From
US$1,799
Per Person
View Trip
11 Day A Journey To Santorini, Sicily & The Riviera with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Athens to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 November 2026
Visit: Greece, Malta, Sicily, Italy, France, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,775
From
US$5,775
Per Person
View Trip
22 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 14 September 2026
Visit: Italy, France, Sicily, Greece, Turkey
Bonus Onboard Credit
Inside
-
Oceanview
-
Balcony
$5,499
Suite
$9,439
From
US$5,499
Per Person
View Trip
8 Day Malta, Croatia And Montenegro with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2027 to Sep 2027
Visit: Spain, Malta, Montenegro, Croatia, Italy
Bonus Onboard Credit
Inside
$1,099
Oceanview
$1,189
Balcony
$1,419
Suite
$2,929
From
US$1,099
Per Person
View Trip
9 Day Authentic Mediterranean Shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 06 June 2027
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
$6,300
Balcony
$6,630
Suite
$12,350
From
US$6,300
Per Person
View Trip
8 Day Spain & France Cruise: Barcelona, Nice & Provence with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Monte Carlo
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 11 June 2026
Visit: Spain, France, Corsica, Monaco
Azamara Always Included
Inside
-
Oceanview
$1,559
Balcony
$2,139
Suite
$3,289
From
US$1,559
Per Person
View Trip
25 Day Spain, Greece & Turkey Cruise: Seville, Athens & Istanbul with Azamara Cruises
Cruise
 (3)

25 Days (24 Nights) Lisbon to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 22 January 2028
Visit: Portugal, Spain, Gibraltar, Algeria (+5 more), Tunisia, Malta, Sicily, Greece, Turkey
Azamara Always Included
Inside
$6,749
Oceanview
$8,089
Balcony
$10,119
Suite
$14,599
From
US$6,749
Per Person
View Trip
15 Day Grecian Gems, Adriatic & Dalmatian Delights with Seabourn
Cruise
 (1)

15 Days (14 Nights) Dubrovnik to Venice
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 23 August 2026
Visit: Croatia, Italy, Albania, Greece, Slovenia
Yours to Explore
Inside
-
Oceanview
$9,899
Balcony
$14,199
Suite
-
From
US$9,899
Per Person
View Trip
15 Day Iberia & Italian Treasures with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 21 December 2026
Visit: Portugal, Spain, France, Italy, Corsica
Your World Inclusions
Exclusive Savings
Inside
$3,375
Oceanview
$3,712
Balcony
$5,550
Suite
$7,500
From
US$3,375
Save 5,623
Per Person
View Trip
19 Day An Extended Journey Across The Mediterranean’s Western Shores with Explora Journeys
Cruise
 (1)

19 Days (18 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 24 January 2027
Visit: Spain, France, Italy, Sicily, Tunisia, Algeria
Inside
-
Oceanview
-
Balcony
-
Suite
$9,240
From
US$9,240
Per Person
View Trip
8 Day Island Hopping in the Mediterranean with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 13 May 2026
Visit: Malta, Sicily, Sardinia, Corsica, Italy, France
Inside
-
Oceanview
-
Balcony
$10,130
Suite
$17,170
From
US$10,130
Per Person
View Trip
15 Day Mediterranean And Greece with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 24 September 2027
Visit: Italy, France, Corsica, Spain, Sicily, Greece, Turkey
Bonus Onboard Credit
Inside
$2,229
Oceanview
$2,439
Balcony
$2,659
Suite
$5,749
From
US$2,229
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 23 July 2027
Visit: Italy, Spain, Sardinia, Corsica
Bonus Onboard Credit
Inside
$1,179
Oceanview
$1,279
Balcony
$1,349
Suite
$2,649
From
US$1,179
Per Person
View Trip
11 Day A Journey From Amalfi’s Cliffs To Andalusian Sun with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 January 2027
Visit: Italy, Sardinia, Spain, Morocco
Inside
-
Oceanview
-
Balcony
-
Suite
$5,390
From
US$5,390
Per Person
View Trip
10 Day A Journey From Italian Gems To Spain’s Southern Coast with Explora Journeys
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 05 March 2027
Visit: Italy, France, Corsica, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,180
From
US$5,180
Per Person
View Trip
8 Day Mediterranean Vistas with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 03 August 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia, Slovenia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,699
Oceanview
$2,999
Balcony
$4,299
Suite
$5,049
From
US$2,699
Save 2,699
Per Person
View Trip
11 Day Ancient Shores of the Mediterranean with Ponant
Cruise
 (1)

11 Days (10 Nights) Valletta to Malaga
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 31 October 2026
Visit: Malta, Sicily, Tunisia, Algeria, Spain
Inside
-
Oceanview
-
Balcony
$8,950
Suite
$16,710
From
US$8,950
Per Person
View Trip
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