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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 618 unique cruise itineraries with 1183 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 681 departures starting between March 2026 and October 2028.
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618 Cruises (681 Cruise Departures)
15 Day Sublime Spain with Regent Seven Seas
Cruise

15 Days (14 Nights) Lisbon to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 17 October 2027
Visit: Portugal, Spain, Morocco, France, Monaco, Italy, Corsica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,299
Suite
$12,671
From
US$11,299
Save 18,699
Per Person
View Trip
8 Day Ionian Exploration with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 October 2027
Visit: Greece, Turkey, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$4,491
From
US$2,599
Save 2,599
Per Person
View Trip
8 Day Iberian Peninsula & Sicily with Ponant
Cruise
 (1)

8 Days (7 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 28 April 2026
Visit: Spain, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$6,260
Suite
$11,700
From
US$6,260
Per Person
View Trip
8 Day Riviera Radiance with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 22 October 2027
Visit: Italy, France, Spain
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,543
Suite
$4,483
From
US$2,543
Save 2,655
Per Person
View Trip
12 Day Idyllic Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 13 September 2028
Visit: Italy, Sardinia, Corsica, Spain
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,021
Suite
$17,640
From
US$15,021
Save 18,969
Per Person
View Trip
10 Day Italian Interlude with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 24 March 2028
Visit: Spain, Sardinia, Sicily, Greece, Croatia, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,545
Oceanview
$2,788
Balcony
$4,291
Suite
$6,134
From
US$2,545
Save 2,653
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 23 July 2027
Visit: Italy, Spain, Sardinia, Corsica
Inside
$1,119
Oceanview
$1,209
Balcony
$1,329
Suite
$2,699
From
US$1,119
Per Person
View Trip
12 Day Treasures of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Visit: Italy, Sicily, Malta, Tunisia, Algeria, Spain, Portugal
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,177
Suite
$19,591
From
US$15,177
Save 19,113
Per Person
View Trip
16 Day Italy, France & Spain Cruise: Rome, Barcelona & Seville with Azamara Cruises
Cruise
 (3)

16 Days (15 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 December 2027
Visit: Italy, France, Spain, Gibraltar, Portugal
Azamara Always Included
Exclusive Savings
Inside
$3,561
Oceanview
$4,454
Balcony
$5,608
Suite
$8,392
From
US$3,561
Save 68
Per Person
View Trip
11 Day Nice to Lisbon with Silversea
Cruise

11 Days (10 Nights) Nice to Lisbon
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 30 August 2026
Visit: France, Spain, Gibraltar, Portugal
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$6,000
Balcony
$6,780
Suite
$10,680
From
US$6,000
Save 4,000
Per Person
View Trip
8 Day Spain, France & Italy with Seabourn
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 25 September 2027
Visit: Spain, France, Corsica, Sardinia, Italy
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,345
Suite
$8,594
From
US$5,345
Save 94
Per Person
View Trip
11 Day Mountains & Mystery with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 17 July 2027
Visit: Italy, Sicily, Malta, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,489
Suite
$7,205
From
US$4,489
Save 4,709
Per Person
View Trip
11 Day Romantic Mediterranean with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Valletta to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 20 September 2026
Visit: Malta, Sicily, Italy, Sardinia, France, Spain
Your World Inclusions
Exclusive Savings
Inside
$3,271
Oceanview
$3,416
Balcony
$5,162
Suite
$7,102
From
US$3,271
Save 3,427
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 July 2026
Visit: Italy, France, Corsica, Spain
Inside
$1,429
Oceanview
$1,359
Balcony
$1,659
Suite
$2,879
From
US$1,359
Per Person
View Trip
8 Day France Cruise: Marseille, Nice & St. Tropez with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Nice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 26 May 2026
Visit: Spain, France
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,576
Suite
-
From
US$2,576
Save 63
Per Person
View Trip
8 Day Spain Intensive Cruise: Barcelona, Valencia & Malaga with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Malaga
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 11 March 2028
Visit: Spain, Gibraltar
Azamara Always Included
Inside
$1,679
Oceanview
$2,089
Balcony
$2,625
Suite
$3,915
From
US$1,679
Per Person
View Trip
9 Day Knights & Sunsets with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 20 November 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,894
Suite
$7,070
From
US$5,894
Save 11,104
Per Person
View Trip
8 Day Regards From The Riviera with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 September 2027
Visit: Italy, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,099
Oceanview
$2,249
Balcony
$3,319
Suite
$4,774
From
US$2,099
Save 2,099
Per Person
View Trip
15 Day Croatia, Montenegro, Italy, Monaco & France with Seabourn
Cruise

15 Days (14 Nights) Dubrovnik to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy, Monaco, France, Spain
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,692
Suite
$15,689
From
US$9,692
Save 167
Per Person
View Trip
9 Day Riviera Charm Including Monaco Grand Prix with Emerald Cruises
New ReleaseCruise

9 Days (8 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 04 June 2027
Visit: France, Monaco, Italy
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$10,785
From
US$10,785
Save 13,405
Per Person
View Trip
10 Day Best Of The Mediterranean Cruise: La Goulette, Valletta & Siracusa with Azamara Cruises
Cruise
 (3)

10 Days (9 Nights) Malaga to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 29 January 2028
Visit: Spain, Algeria, Tunisia, Malta, Sicily, Greece
Azamara Always Included
Exclusive Savings
Inside
$2,551
Oceanview
$3,017
Balcony
$3,783
Suite
$5,403
From
US$2,551
Save 58
Per Person
View Trip
23 Day Mediterranean Mosaic: Italy, Croatia & Greece with Seabourn
Cruise

23 Days (22 Nights) Genoa to Athens
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 April 2027
Visit: Italy, Corsica, Sardinia, Tunisia (+5 more), Sicily, Malta, Croatia, Montenegro, Greece
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,287
Suite
$33,031
From
US$16,287
Save 287
Per Person
View Trip
15 Day Egypt, Greece & Italy Cruise: Alexandria, Crete & Salerno with Azamara Cruises
Cruise
 (8)

15 Days (14 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 October 2027
Visit: Greece, Turkey, Egypt, Malta, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$3,930
Oceanview
$4,444
Balcony
$5,793
Suite
$8,218
From
US$3,930
Save 89
Per Person
View Trip
11 Day French Riviera, Corsica and Monaco Grand Prix with Scenic
New ReleaseCruise

11 Days (10 Nights) Nice to Rome
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 30 May 2027
Visit: France, Corsica, Italy, Monaco
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,117
Suite
$17,997
From
US$14,117
Save 18,073
Per Person
View Trip
15 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (8)

15 Days (14 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Visit: Spain, France, Italy, Sicily, Greece
Azamara Always Included
Exclusive Savings
Inside
$2,969
Oceanview
$3,357
Balcony
$3,987
Suite
$6,344
From
US$2,969
Save 50
Per Person
View Trip
8 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Visit: Spain, France, Italy
Azamara Always Included
Inside
$1,559
Oceanview
$1,779
Balcony
$2,039
Suite
$3,347
From
US$1,559
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: May 2026 to Jun 2026
Visit: France, Italy, Malta, Sicily, Corsica
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
$6,650
Balcony
$7,350
Suite
$15,460
From
US$6,650
Per Person
View Trip
10 Day Spellbinding Mediterranean with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 31 October 2027
Visit: Italy, Croatia, Greece, Turkey
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,877
Suite
$7,759
From
US$6,877
Save 12,121
Per Person
View Trip
10 Day Mediterranean Masterpieces with Oceania Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 02 June 2027
Visit: Spain, France, Italy, Corsica, Sardinia, Sicily
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,761
Suite
$6,331
From
US$3,761
Save 3,937
Per Person
View Trip
8 Day A Grand Journey From Egypt’s Secrets To Mediterranean & Aegean Adventures with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Luxor to Athens
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 18 March 2027
Visit: Egypt, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$4,485
Suite
$4,915
From
US$4,485
Per Person
View Trip
Results: 91-120 of 618

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