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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 614 unique cruise itineraries with 1183 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 677 departures starting between March 2026 and October 2028.
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614 Cruises (677 Cruise Departures)
18 Day Mediterranean Mystique with Regent Seven Seas
Cruise

18 Days (17 Nights) Athens to Monte Carlo
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 19 June 2026
Visit: Greece, Malta, Sicily, Tunisia (+5 more), Spain, Portugal, Morocco, France, Monaco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,144
Suite
-
From
US$17,144
Save 27,754
Per Person
View Trip
9 Day Monaco, Italy, France & Spain with Seabourn
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 29 June 2027
Visit: Italy, Monaco, France, Spain
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,736
Suite
$8,927
From
US$5,736
Save 102
Per Person
View Trip
18 Day Mediterranean Holiday Cruise: Greece, Egypt & Spain with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Athens to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 December 2026
Visit: Greece, Egypt, Malta, Sicily, Italy, Spain
Azamara Always Included
Exclusive Savings
Inside
$3,989
Oceanview
$4,551
Balcony
$5,211
Suite
$8,402
From
US$3,989
Save 80
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 20 April 2026
Visit: France, Corsica, Sardinia, Spain
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
$6,850
Balcony
$7,250
Suite
$15,080
From
US$6,850
Per Person
View Trip
15 Day Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 August 2026
Visit: Italy, Spain, France, Sardinia, Sicily
Inside
$2,959
Oceanview
$3,119
Balcony
$3,629
Suite
$7,777
From
US$2,959
Per Person
View Trip
8 Day Spain Intensive Cruise: Malaga, Valencia & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Malaga to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 April 2027
Visit: Spain, Gibraltar
Azamara Always Included
Inside
$2,179
Oceanview
$2,431
Balcony
$3,197
Suite
$5,118
From
US$2,179
Per Person
View Trip
12 Day Idyllic Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 07 July 2028
Visit: Spain, Corsica, Italy, Sardinia
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,031
Suite
$17,650
From
US$15,031
Save 18,959
Per Person
View Trip
11 Day Italy & France Spotlight with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 22 May 2026
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$3,323
Oceanview
$3,662
Balcony
-
Suite
-
From
US$3,323
Save 3,475
Per Person
View Trip
8 Day A Grand Journey From Egypt’s Secrets To Mediterranean & Aegean Adventures with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Luxor to Athens
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 18 March 2027
Visit: Egypt, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$4,485
Suite
$4,915
From
US$4,485
Per Person
View Trip
11 Day Seville, Granada, Murcia And French Riviera with Seabourn
Cruise

11 Days (10 Nights) Lisbon to Genoa
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 08 April 2027
Visit: Portugal, Spain, France, Corsica, Italy
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,082
Suite
$9,181
From
US$6,082
Save 105
Per Person
View Trip
12 Day Spain & Italy Cruise: Barcelona, Salerno & Rome with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 20 February 2027
Visit: Spain, Sardinia, Tunisia, Malta, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$3,672
Oceanview
$4,293
Balcony
$4,924
Suite
$7,669
From
US$3,672
Save 87
Per Person
View Trip
13 Day Monte Carlo to Lisbon with Silversea
Cruise

13 Days (12 Nights) Monte Carlo to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 15 November 2027
Visit: Monaco, France, Spain, Morocco, Portugal
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$5,680
Balcony
$6,240
Suite
$16,100
From
US$5,680
Save 1,420
Per Person
View Trip
7 Day Barcelona to Monte Carlo with Silversea
Cruise

7 Days (6 Nights) Barcelona to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 24 August 2026
Visit: Spain, France, Italy, Corsica, Monaco
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,550
Suite
$5,610
From
US$4,550
Save 1,950
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: May 2026 to Jun 2026
Visit: France, Italy, Malta, Sicily, Corsica
All-Inclusive Fare
Last Minute Fare
Exclusive Savings
Inside
-
Oceanview
$6,650
Balcony
$7,350
Suite
$15,460
From
US$6,650
Save 2,760
Per Person
View Trip
19 Day Splendid Southern Seas with Oceania Cruises
Cruise

19 Days (18 Nights) Istanbul to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 19 February 2028
Visit: Turkey, Greece, Malta, Sicily (+5 more), Italy, Sardinia, Corsica, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,453
Suite
$9,848
From
US$6,453
Save 6,745
Per Person
View Trip
8 Day Island Hopping in the Mediterranean with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 13 May 2026
Visit: Malta, Sicily, Sardinia, Corsica, Italy, France
Inside
-
Oceanview
-
Balcony
$10,130
Suite
$17,170
From
US$10,130
Per Person
View Trip
11 Day Treasures of the Western Mediterranean with Ponant
Cruise
 (2)

11 Days (10 Nights) Florence to Malaga
Cruise Line: Ponant
Ship: Le Boreal
Departure: 03 October 2027
Visit: Italy, Monaco, France, Spain
Inside
-
Oceanview
$6,990
Balcony
$7,350
Suite
$13,610
From
US$6,990
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 01 April 2027
Visit: France, Italy, Malta, Sicily, Corsica
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$6,370
Balcony
$7,770
Suite
$14,850
From
US$6,370
Save 2,730
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Visit: Spain, Corsica, Italy
Inside
$1,159
Oceanview
$1,259
Balcony
$1,399
Suite
$3,139
From
US$1,159
Per Person
View Trip
11 Day Radiant Rivieras with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 November 2026
Visit: Spain, France, Monaco, Italy
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$3,421
Oceanview
$4,003
Balcony
$3,829
Suite
$5,381
From
US$3,421
Save 3,577
Per Person
View Trip
10 Day Ancient Athenian Adventure with Oceania Cruises
Cruise

10 Days (9 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 18 March 2028
Visit: Greece, Montenegro, Croatia, Malta, Sicily, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,516
Suite
$6,038
From
US$3,516
Save 3,682
Per Person
View Trip
8 Day Western Mediterranean Cruise: Italy, France & Spain with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departures: Oct 2026 to Oct 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$1,779
Oceanview
$2,109
Balcony
$2,684
Suite
$3,935
From
US$1,779
Save 52
Per Person
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Valletta to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: May 2026 to Jul 2026
Visit: Malta, Sicily, Italy
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$8,905
From
US$8,905
Save 27,081
Per Person
View Trip
7 Day Monte Carlo to Barcelona with Silversea
Cruise

7 Days (6 Nights) Monte Carlo to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 30 August 2026
Visit: Monaco, France, Spain
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,130
Suite
$5,750
From
US$4,130
Save 1,770
Per Person
View Trip
10 Day From the Iberian Shores to the Italian Coast with Ponant
Cruise

10 Days (9 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 04 April 2027
Visit: Spain, Sicily, Italy, Malta
Inside
-
Oceanview
-
Balcony
$6,880
Suite
$12,750
From
US$6,880
Per Person
View Trip
7 Day Monte Carlo to Barcelona with Silversea
Cruise

7 Days (6 Nights) Monte Carlo to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 21 June 2026
Visit: Monaco, France, Spain
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$4,250
Suite
$7,580
From
US$4,250
Per Person
View Trip
8 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Visit: Spain, France, Italy
Azamara Always Included
Inside
$1,559
Oceanview
$1,779
Balcony
$2,039
Suite
$3,347
From
US$1,559
Per Person
View Trip
10 Day Spanish Shores & Beyond with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Palma de Mallorca to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 19 September 2026
Visit: Spain, Sardinia, Corsica, Monaco, France
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$6,291
Balcony
-
Suite
$8,861
From
US$6,291
Save 8,699
Per Person
View Trip
11 Day Renaissance & Rivieras with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 June 2027
Visit: Italy, Sicily, Sardinia, Corsica, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,129
Oceanview
$3,371
Balcony
$5,360
Suite
$7,397
From
US$3,129
Save 3,269
Per Person
View Trip
12 Day Treasures of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2027
Visit: Italy, Sicily, Malta, Tunisia, Algeria, Spain, Portugal
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,177
Suite
$19,591
From
US$15,177
Save 19,113
Per Person
View Trip
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