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Mediterranean Luxury Cruises

Explore the best luxury cruises sailing in and around the Mediterranean. Choose from 745 unique cruise itineraries with 1204 past traveler reviews from 10 leading cruise lines. September is the most popular month to join a luxury cruise sailing in and around the Mediterranean with 848 departures starting between April 2026 and November 2028.
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745 Cruises (848 Cruise Departures)
8 Day Italy And Adriatic with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Jun 2026 to Aug 2026
Visit: Italy, Greece, Montenegro, Croatia
Bonus Onboard Credit
Inside
$1,099
Oceanview
$1,099
Balcony
$1,519
Suite
$2,979
From
US$1,099
Per Person
View Trip
8 Day Italy And Adriatic with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Visit: Spain, Italy, Sicily, Greece, Montenegro
Inside
$1,249
Oceanview
$1,399
Balcony
$1,629
Suite
$3,009
From
US$1,249
Per Person
View Trip
9 Day Legendary Shores of Italy and Croatia with Ponant
Cruise
 (2)

9 Days (8 Nights) Rome to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 12 May 2027
Visit: Italy, Sicily, Croatia
Inside
-
Oceanview
$6,650
Balcony
$7,010
Suite
$13,080
From
US$6,650
Per Person
View Trip
40 Day Athens To Lisbon Grand Voyage with Azamara Cruises
Cruise
 (3)

40 Days (39 Nights) Athens to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 February 2028
Visit: Greece, Egypt, Cyprus, Turkey (+6 more), Sicily, Italy, France, Spain, Gibraltar, Portugal
Azamara Always Included
Inside
$10,839
Oceanview
$12,239
Balcony
$15,439
Suite
$22,639
From
US$10,839
Per Person
View Trip
10 Day Italy & Spain Cruise: Florence, Portofino & Barcelona with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 August 2026
Visit: Spain, France, Monaco, Italy
Azamara Always Included
Inside
-
Oceanview
$3,499
Balcony
$4,709
Suite
$5,459
From
US$3,499
Per Person
View Trip
11 Day Best of the Amalfi Coast, Corinth Canal Passage & Greek Isles with Emerald Cruises
New ReleaseCruise
 (3)

11 Days (10 Nights) Rome to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 02 May 2026
Visit: Italy, Sicily, Malta, Greece
Inside
-
Oceanview
$8,995
Balcony
-
Suite
$11,745
From
US$8,995
Per Person
View Trip
9 Day Isle of Beauty & Italian Shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 August 2026
Visit: France, Corsica, Italy
Inside
-
Oceanview
-
Balcony
$6,860
Suite
$14,230
From
US$6,860
Per Person
View Trip
15 Day Atlantic To Adriatic Sea with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lisbon to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 11 June 2026
Visit: Portugal, Spain, Italy, Sicily, Malta, Montenegro, Croatia
Your World Inclusions
Exclusive Savings
Inside
$3,465
Oceanview
$3,640
Balcony
$5,915
Suite
$7,420
From
US$3,465
Save 6,433
Per Person
View Trip
21 Day An Extended Journey Through Layers Of Coast, Culture & Time with Explora Journeys
Cruise
 (1)

21 Days (20 Nights) Rome to Athens
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 05 March 2027
Visit: Italy, France, Corsica, Spain, Sicily, Malta, Greece
Inside
-
Oceanview
-
Balcony
-
Suite
$10,885
From
US$10,885
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2027 to Sep 2027
Visit: Italy, Corsica, Spain
Bonus Onboard Credit
Inside
$1,069
Oceanview
$1,159
Balcony
$1,309
Suite
$2,899
From
US$1,069
Per Person
View Trip
22 Day France, Italy, Croatia & Greece Cruise: Marseille, Florence, Dubrovnik & Athens with Azamara Cruises
Cruise
 (8)

22 Days (21 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 March 2027
Visit: Spain, France, Italy, Sicily (+4 more), Montenegro, Croatia, Slovenia, Greece
Azamara Always Included
Inside
$5,839
Oceanview
$6,539
Balcony
$8,149
Suite
$11,529
From
US$5,839
Per Person
View Trip
8 Day French & Italian Rivieras with Corsica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Sakara
Departures: Apr 2026 to Aug 2027
Visit: France, Monaco, Italy, Corsica
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$9,265
From
US$9,265
Save 500
Per Person
View Trip
11 Day Italy, Malta & Montenegro Cruise: Amalfi, Valletta & Kotor with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 09 June 2028
Visit: Italy, Sicily, Malta, Montenegro, Croatia, Slovenia
Azamara Always Included
Inside
$3,099
Oceanview
$3,449
Balcony
$3,979
Suite
$6,039
From
US$3,099
Per Person
View Trip
24 Day Mediterranean Constellation with Oceania Cruises
Cruise
 (2)

24 Days (23 Nights) Lisbon to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 24 June 2026
Visit: Portugal, Spain, France, Italy (+5 more), Greece, Turkey, Tunisia, Sicily, Monaco
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$8,249
Balcony
$12,949
Suite
$17,199
From
US$8,249
Save 8,249
Per Person
View Trip
11 Day Romantic Mediterranean with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Valletta to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 20 September 2026
Visit: Malta, Sicily, Italy, Sardinia, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,699
Oceanview
$3,749
Balcony
$5,399
Suite
$7,099
From
US$3,699
Save 3,699
Per Person
View Trip
10 Day Ferdinand's Fantasy with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 16 August 2027
Visit: Spain, Morocco, Gibraltar, Portugal
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,799
Oceanview
$3,049
Balcony
$4,699
Suite
$6,599
From
US$2,799
Save 2,799
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 02 July 2027
Visit: Italy, Spain, France, Corsica (+5 more), Malta, Montenegro, Croatia, Greece, Sicily
Bonus Onboard Credit
Inside
$3,189
Oceanview
$3,579
Balcony
$4,119
Suite
$8,179
From
US$3,189
Per Person
View Trip
8 Day Coastal Kaleidoscope with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 26 September 2027
Visit: Italy, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$1,899
Oceanview
$2,199
Balcony
$3,299
Suite
$4,799
From
US$1,899
Save 1,899
Per Person
View Trip
11 Day A Journey Through The Mediterranean’s Historic Crossroads with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 04 January 2027
Visit: Italy, Sicily, Malta, Tunisia
Inside
-
Oceanview
-
Balcony
-
Suite
$5,390
From
US$5,390
Per Person
View Trip
22 Day Italy, Spain, Greece And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Visit: Spain, Corsica, Italy, Malta (+4 more), Montenegro, Croatia, Greece, Sicily
Bonus Onboard Credit
Inside
$3,029
Oceanview
$3,629
Balcony
$4,109
Suite
$8,639
From
US$3,029
Per Person
View Trip
15 Day Spain And Italy with Cunard
Cruise
 (6)

15 Days (14 Nights) London to London
Cruise Line: Cunard
Ship: Queen Mary 2
Departure: 31 March 2028
Visit: England, Spain, Italy, Sardinia
Inside
$3,039
Oceanview
$4,139
Balcony
$4,389
Suite
$9,539
From
US$3,039
Per Person
View Trip
10 Day Authentic Mediterranean shores with Ponant
Cruise
 (2)

10 Days (9 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 October 2026
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
$8,510
Balcony
$8,980
Suite
$18,710
From
US$8,510
Per Person
View Trip
15 Day Iberian Peninsula Cruise: Portugal & Spain with Azamara Cruises
Cruise
 (8)

15 Days (14 Nights) Lisbon to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 February 2027
Visit: Portugal, Spain, Gibraltar, Morocco
Azamara Always Included
Inside
$3,519
Oceanview
$4,019
Balcony
$4,539
Suite
$7,069
From
US$3,519
Per Person
View Trip
13 Day Dalmatian Diversion with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 03 October 2027
Visit: Spain, France, Monaco, Italy, Corsica, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,349
Oceanview
$3,649
Balcony
$6,299
Suite
$8,499
From
US$3,349
Save 3,349
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 July 2026
Visit: Italy, France, Corsica, Spain
Inside
$1,149
Oceanview
$1,259
Balcony
$1,409
Suite
$2,619
From
US$1,149
Per Person
View Trip
11 Day Invitation To Iberia with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2027
Visit: Italy, France, Spain, Portugal
Your World Inclusions
Exclusive Savings
Inside
$1,890
Oceanview
$2,100
Balcony
$3,150
Suite
$4,340
From
US$1,890
Save 3,508
Per Person
View Trip
8 Day Grecian & Roman Gems with Seabourn
Cruise
 (1)

8 Days (7 Nights) Athens to Rome
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 25 October 2026
Visit: Greece, Albania, Italy
Yours to Explore
Inside
-
Oceanview
$6,299
Balcony
$9,299
Suite
$13,799
From
US$6,299
Per Person
View Trip
11 Day Radiant Rivieras with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 November 2026
Visit: Spain, France, Monaco, Italy
Your World Inclusions
Exclusive Savings
Inside
$3,699
Oceanview
$4,799
Balcony
$3,605
Suite
$4,865
From
US$3,605
Save 6,693
Per Person
View Trip
12 Day A Journey From Ligurian Shores To The Cyclades' Dazzling Beauty with Explora Journeys
Cruise
 (1)

12 Days (11 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 March 2027
Visit: Spain, Italy, Sicily, Malta, Greece
Inside
-
Oceanview
-
Balcony
-
Suite
$6,015
From
US$6,015
Per Person
View Trip
11 Day Hidden Gems of the Western Mediterranean with Ponant
Cruise
 (1)

11 Days (10 Nights) Nice to Barcelona
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 21 June 2027
Visit: France, Italy, Corsica, Spain
Inside
-
Oceanview
-
Balcony
$7,650
Suite
$14,170
From
US$7,650
Per Person
View Trip
Results: 61-90 of 745

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