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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 233 unique cruise itineraries to Sicily, departing from Athens, Barcelona, Florence, Genoa, Istanbul and more. September and October are the most popular months to cruise to Sicily and we have over 1,372 departures available from twenty of the world's leading cruise lines.
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233 Cruises (1,372 Cruise Departures)
8 Day Glorious Greek Isles to Spanish Sunsets with Virgin Voyages
Cruise
 (4)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 20 October 2024
Countries Visited: Greece, Sicily, Spain
INSIDE
$1,810
OCEANVIEW
$2,023
BALCONY
$2,542
SUITE
$4,240
From 1,810
View Trip
12 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (1)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 15 July 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,012
OCEANVIEW
$5,473
BALCONY
$6,163
SUITE
$8,232
From 5,012
View Trip
8 Day Greece & Italy Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 15 August 2025
Countries Visited: Greece, Sicily, Spain
Exclusive Deal
INSIDE
$2,226
OCEANVIEW
$2,260
BALCONY
$3,239
SUITE
$4,254
Save 851
From 1,887
View Trip
13 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (1)

13 Days (12 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 11 April 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,505
OCEANVIEW
$5,967
BALCONY
$6,657
SUITE
$8,380
From 5,505
View Trip
11 Day Amalfi Coast, Sicily & Gulf of Naples with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 19 October 2024
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,301
Save 3,144
From 14,301
View Trip
11 Day Italy Intensive Voyage with Azamara Cruises
Cruise

11 Days (10 Nights) Venice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 19 June 2024
Countries Visited: Italy, Montenegro, Sicily
INSIDE
$3,403
OCEANVIEW
$3,562
BALCONY
$6,654
SUITE
$8,037
From 3,402
View Trip
9 Day A Circumnavigation of Sicily - with Smithsonian Journeys with Ponant
Cruise

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departures: Jun 2025 to Aug 2025
Countries Visited: Malta, Sicily, Tunisia
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,067
SUITE
$17,103
Save 193
From 10,067
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 29 April 2025
Countries Visited: Spain, Tunisia, Sicily
Exclusive Deal
INSIDE
$600
OCEANVIEW
-
BALCONY
$807
SUITE
$1,075
From 600
View Trip
8 Day Ancient Wonders and Culinary Delights: Cruising Southern Italy and Sicily - with Smithsonian Journey with Ponant
Cruise

8 Days (7 Nights) Valletta to Livorno
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 08 September 2024
Countries Visited: Malta, Sicily, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$12,143
SUITE
$24,452
Save 237
From 12,143
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8 Day Highlights of Southern Italy with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 29 June 2024
Countries Visited: Italy, Sicily, Croatia
Exclusive Savings
INSIDE
-
OCEANVIEW
$7,359
BALCONY
-
SUITE
$10,343
Save 136
From 7,359
View Trip
8 Day A Greek & Italian Odyssey with Regent Seven Seas
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 April 2026
Countries Visited: Greece, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,207
SUITE
$11,682
Save 5,693
From 10,207
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+5 more), Viking Saturn, Viking Sky, Viking Star, Viking Venus, Viking Vesta
Departures: Aug 2024 to Aug 2026
Countries Visited: Italy, Sicily, Croatia
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,945
SUITE
$7,420
Save 1,076
From 4,945
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17 Day Taste of Italy & Italian Treasures with Scenic
Tour + Cruise

17 Days Venice to Valletta
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 02 May 2024
Countries Visited: Italy, Sicily, Malta
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$22,873
SUITE
$28,244
Save 467
From 22,873
View Trip
9 Day Italian Treasures with Scenic
Cruise

9 Days (8 Nights) Rome to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 10 May 2024
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,988
SUITE
$14,928
Save 4,107
From 10,988
View Trip
11 Day Jewels of the Italian Riviera with Ponant
Cruise

11 Days (10 Nights) Nice to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 28 June 2025
Countries Visited: France, Italy, Sicily
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,814
SUITE
$19,360
Save 206
From 10,814
View Trip
9 Day Authentic Shores of Sicily with Ponant
Cruise

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 30 April 2024
Countries Visited: Malta, Sicily, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$12,183
SUITE
$31,097
Save 237
From 12,183
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+4 more), Viking Saturn, Viking Vela, Viking Venus, Viking Vesta
Departures: Jul 2024 to Sep 2026
Countries Visited: Italy, Croatia, Sicily
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$5,935
SUITE
$10,390
Save 1,131
From 5,935
View Trip
8 Day Greece & Spain with Royal Caribbean
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 01 July 2024
Countries Visited: Greece, Sicily, Spain
Exclusive Deal
INSIDE
$2,281
OCEANVIEW
$2,261
BALCONY
$2,694
SUITE
$6,666
Save 824
From 1,771
View Trip
8 Day Italian & Aegean Sampler with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 30 April 2026
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$4,644
SUITE
$7,297
Save 2,036
From 4,644
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departure: 05 October 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
$2,955
OCEANVIEW
$3,384
BALCONY
$3,661
SUITE
$4,757
Save 1,172
From 2,527
View Trip
7 Day Greece, Italy & Spain Cruise with Royal Caribbean
Cruise

7 Days (6 Nights) Athens to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 27 October 2024
Countries Visited: Greece, Sicily, Spain
Exclusive Deal
INSIDE
$1,422
OCEANVIEW
$1,764
BALCONY
$2,217
SUITE
$3,115
Save 612
From 1,288
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Valletta to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: May 2026 to Jul 2026
Countries Visited: Malta, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$9,747
BALCONY
-
SUITE
$13,261
Save 2,102
From 9,747
View Trip
8 Day Ionian Sea Adventure with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Sakara
Departures: Apr 2024 to Jun 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,479
Save 2,090
From 7,479
View Trip
8 Day Coastal Gems of Italy & Croatia with Emerald Cruises
Cruise

8 Days (7 Nights) Venice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: Jun 2024 to Aug 2024
Countries Visited: Italy, Croatia, Sicily
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,707
BALCONY
-
SUITE
$8,672
Save 1,568
From 6,707
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 26 July 2025
Countries Visited: Greece, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,579
BALCONY
-
SUITE
$8,890
Save 1,566
From 6,579
View Trip
12 Day Along the Mediterranean Sea with the Mucem with Ponant
Cruise

12 Days (11 Nights) Athens to Lisbon
Cruise Line: Ponant
Ship: L'Austral
Departure: 10 October 2024
Countries Visited: Greece, Sicily, Sardinia
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$12,433
SUITE
$26,231
Save 237
From 12,433
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 11 July 2026
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$9,747
BALCONY
-
SUITE
$13,261
Save 2,098
From 9,747
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Rome to Rome
Ship: Norwegian Epic
Departure: 22 September 2025
Countries Visited: Italy, Greece, Sicily
Free At Sea Offer
INSIDE
$3,385
OCEANVIEW
-
BALCONY
$5,252
SUITE
$5,403
From 3,385
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Southbound with Tauck
Cruise

12 Days (11 Nights) Rome to Valletta
Operated By: Tauck
Departures: Jun 2025 to Oct 2025
Trip Styles: Group, Cruise
Countries Visited: Italy, Sicily, Malta
From 18,170
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Trip Styles: Group, Cruise
Countries Visited: Malta, Sicily, Italy
From 18,940
View Trip
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