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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 422 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bologna and more. October is the most popular month to cruise to Sicily and we have over 2,193 departures available from twenty-three of the world's leading cruise lines.
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422 Cruises (2,193 Cruise Departures)
11 Day Made in Italy, the Luxury Edition with Ponant
Cruise
 (2)

11 Days (10 Nights) Florence to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 08 September 2027
Visit: Italy, Sicily
Exclusive Savings
Inside
-
Oceanview
$20,567
Balcony
$21,721
Suite
$45,709
From
A$20,567
Save 613
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Sep 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,022
Suite
$8,864
From
A$6,022
Save 1,415
Per Person
View Trip
9 Day Tribute to Maria Callas with Ponant
Cruise
 (2)

9 Days (8 Nights) Athens to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 29 September 2027
Visit: Greece, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,716
Suite
$22,211
From
A$11,716
Save 344
Per Person
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Kaia, Emerald Sakara
Departures: May 2027 to Nov 2028
Visit: Italy, Sicily, Malta
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
$9,041
Balcony
-
Suite
$12,251
From
A$9,041
Save 3,154
Per Person
View Trip
9 Day Authentic Mediterranean Shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 06 June 2027
Visit: Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
$7,923
Balcony
$8,360
Suite
$15,751
From
A$7,923
Save 227
Per Person
View Trip
11 Day Italy Intensive Cruise: Venice, Sicily & Amalfi with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Venice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 05 May 2027
Visit: Italy, Montenegro, Sicily
Azamara Always Included
Exclusive Savings
Inside
$4,866
Oceanview
$5,601
Balcony
$7,306
Suite
$11,128
From
A$4,866
Save 73
Per Person
View Trip
11 Day Italy Intensive Cruise: Amalfi, Siracusa & Venice with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 April 2028
Visit: Italy, Sicily, Montenegro
Azamara Always Included
Exclusive Savings
Inside
$3,141
Oceanview
$3,415
Balcony
$4,189
Suite
$5,894
From
A$3,141
Per Person
View Trip
8 Day Authentic Mediterranean Shores with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 08 April 2027
Visit: Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,174
Suite
$13,499
From
A$7,174
Save 206
Per Person
View Trip
9 Day Legendary Shores of Italy and Croatia with Ponant
Cruise
 (2)

9 Days (8 Nights) Rome to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 12 May 2027
Visit: Italy, Sicily, Croatia
Exclusive Savings
Inside
-
Oceanview
$8,389
Balcony
$8,845
Suite
$16,692
From
A$8,389
Save 241
Per Person
View Trip
9 Day Legendary Shores of Italy and Croatia with Ponant
Cruise
 (2)

9 Days (8 Nights) Venice to Rome
Cruise Line: Ponant
Ship: Le Boreal
Departure: 20 May 2027
Visit: Italy, Croatia, Sicily
Exclusive Savings
Inside
-
Oceanview
$7,923
Balcony
$8,360
Suite
$15,751
From
A$7,923
Save 227
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Sep 2026 to Jul 2028
Visit: Italy, Sicily, Croatia
Viking Savings Event
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,630
Suite
$8,374
From
A$5,630
Save 1,411
Per Person
View Trip
12 Day Italy Intensive Cruise: Bologna, Sicily & Amalfi with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Venice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 May 2027
Visit: Italy, Montenegro, Sicily
Azamara Always Included
Exclusive Savings
Inside
$5,398
Oceanview
$6,211
Balcony
$10,004
Suite
$12,954
From
A$5,398
Save 81
Per Person
View Trip
6 Day Sicilian interlude with Ponant
Cruise
 (2)

6 Days (5 Nights) Palermo to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 June 2027
Visit: Sicily, Italy, Malta
Exclusive Savings
Inside
-
Oceanview
$4,948
Balcony
$5,220
Suite
$9,837
From
A$4,948
Save 142
Per Person
View Trip
11 Day Rome, Florence, Mykonos & More with Virgin Voyages
Cruise
 (2)

11 Days (10 Nights) Rome to Athens
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 31 August 2026
Visit: Italy, Sicily, Greece
Inside
$3,978
Oceanview
$4,549
Balcony
$5,404
Suite
$8,542
From
A$3,978
Per Person
View Trip
10 Day Authentic Mediterranean shores with Ponant
Cruise
 (2)

10 Days (9 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 October 2026
Visit: Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
$11,262
Balcony
$12,535
Suite
$25,745
From
A$11,262
Save 328
Per Person
View Trip
11 Day Italy Intensive Cruise: Florence, Sorrento & Venice with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 August 2028
Visit: Italy, Sicily, Montenegro
Azamara Always Included
Exclusive Savings
Inside
$4,683
Oceanview
$5,065
Balcony
$6,222
Suite
$8,760
From
A$4,683
Per Person
View Trip
9 Day A Celebration of Art Featuring the 61st Venice Biennale with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 01 July 2026
Visit: Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,696
Suite
$22,512
From
A$12,696
Save 374
Per Person
View Trip
7 Day A Journey Through Southern Italian Piazzas, Sicily And Malta’s Historic Shores with Explora Journeys
Cruise
 (1)

7 Days (6 Nights) Rome to Valletta
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 04 January 2027
Visit: Italy, Sicily, Malta
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$4,699
From
A$4,699
Save 96
Per Person
View Trip
8 Day Italy & Greece Cruise: Amalfi Coast, Siracusa & Olympia with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 December 2026
Visit: Italy, Sicily, Greece
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Exclusive Savings
Inside
$2,134
Oceanview
$2,036
Balcony
$2,389
Suite
$4,457
From
A$2,036
Per Person
View Trip
8 Day Greece & Italy Cruise: Olympia, Catania & Amalfi Coast (salerno) with Azamara Cruises
Cruise
 (4)

8 Days (7 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 26 February 2028
Visit: Greece, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$2,141
Oceanview
$2,699
Balcony
$3,513
Suite
$5,336
From
A$2,141
Per Person
View Trip
12 Day Italy Intensive Cruise: Rome, Amalfi & Venice with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 August 2026
Visit: Italy, Sicily, Montenegro
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Exclusive Savings
Inside
$3,335
Oceanview
$3,923
Balcony
-
Suite
-
From
A$3,335
Per Person
View Trip
11 Day Mediterranean Crossroads with Emerald Cruises
New ReleaseCruise
 (3)

11 Days (10 Nights) Athens to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 28 October 2028
Visit: Greece, Sicily, Malta
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
$10,951
Balcony
-
Suite
$14,626
From
A$10,951
Save 3,194
Per Person
View Trip
12 or 13 Day The Amalfi, Sicily and Malta: The Godfather with Aurora Expeditions
New ReleaseCruise

12 or 13 Days Rome to Valletta
Cruise Line: Aurora Expeditions
Ships: Douglas Mawson
Departures: Jul 2026 to May 2027
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
$18,795
Balcony
$19,995
Suite
$31,695
From
A$18,795
Per Person
View Trip
8 Day Under Sail from Sicily to the Greek Islands with Ponant
Cruise

8 Days (7 Nights) Palermo to Athens
Cruise Line: Ponant
Ship: Le Ponant
Departure: 08 June 2027
Visit: Sicily, Italy, Greece
Exclusive Savings
Inside
-
Oceanview
$15,400
Balcony
$24,983
Suite
$27,864
From
A$15,400
Save 460
Per Person
View Trip
11 Day 5th Opera Festival at Sea with Ponant
Cruise

11 Days (10 Nights) Venice to Nice
Cruise Line: Ponant
Ships: Le Boreal, Le Bougainville, Le Dumont d’Urville
Departures: Jun 2026 to Sep 2027
Visit: Italy, Sicily, France
Exclusive Savings
Inside
-
Oceanview
$9,897
Balcony
$10,440
Suite
$19,694
From
A$9,897
Save 514
Per Person
View Trip
11 Day Ancient Civilisations, from Italy to Greece with Ponant
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Champlain
Departure: 01 October 2026
Visit: Italy, Sicily, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$31,295
From
A$31,295
Save 945
Per Person
View Trip
8 Day Highlights of Southern Italy with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 17 June 2028
Visit: Italy, Sicily, Croatia
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
$9,323
Balcony
-
Suite
$12,263
From
A$9,323
Save 2,172
Per Person
View Trip
8 Day Island Odyssey: Malta, Sicily & the Greek Isles with Scenic
New ReleaseCruise

8 Days (7 Nights) Valletta to Athens
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 June 2026
Visit: Malta, Sicily, Greece
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,414
Suite
$16,280
From
A$13,414
Save 2,246
Per Person
View Trip
8 Day Under Sail from Sicily to the Riviera with Ponant
Cruise

8 Days (7 Nights) Palermo to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departure: 24 August 2027
Visit: Sicily, Italy, France
Exclusive Savings
Inside
-
Oceanview
$16,350
Balcony
$24,983
Suite
$28,815
From
A$16,350
Save 490
Per Person
View Trip
12 Day Adriatic, Sicily & the Amalfi Coast with Scenic
New ReleaseCruise

12 Days (11 Nights) Venice to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departures: Jun 2028 to Sep 2028
Visit: Italy, Croatia, Sicily
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,110
Suite
$24,059
From
A$21,110
Save 5,906
Per Person
View Trip
Results: 1-30 of 422

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