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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 258 unique cruise itineraries to Sicily, departing from Antalya, Athens, Barcelona, Bologna, Florence and more. September is the most popular month to cruise to Sicily and we have over 1,254 departures available from twenty-two of the world's leading cruise lines.
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258 Cruises (1,254 Cruise Departures)
8 Day Glorious Greek Isles to Spanish Sunsets with Virgin Voyages
Cruise
 (5)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departures: Oct 2024 to Oct 2025
Countries Visited: Greece, Sicily, Spain
INSIDE
$3,025
OCEANVIEW
$3,388
BALCONY
$2,394
SUITE
$6,851
From (per person) 2,394
View Trip
9 Day Epicurean Delights of Sicily and the Adriatic Coast of Italy with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 10 June 2025
Countries Visited: Malta, Sicily, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$11,439
SUITE
$21,278
Save (per person) 221
From (per person) 11,439
View Trip
9 Day A Circumnavigation of Sicily - with Smithsonian Journeys with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departures: Jun 2025 to Aug 2025
Countries Visited: Malta, Sicily, Tunisia
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$11,301
SUITE
$19,279
Save (per person) 257
From (per person) 11,301
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 22 September 2025
Countries Visited: Italy, Greece, Sicily
INSIDE
$3,598
OCEANVIEW
-
BALCONY
$5,509
SUITE
$6,350
From (per person) 3,598
View Trip
13 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (1)

13 Days (12 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 11 April 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,526
OCEANVIEW
$6,120
BALCONY
-
SUITE
-
From (per person) 5,526
View Trip
8 Day Greece & Italy Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 15 August 2025
Countries Visited: Greece, Sicily, Spain
Exclusive Deal
INSIDE
$1,911
OCEANVIEW
$2,033
BALCONY
$2,723
SUITE
$3,427
Save (per person) 883
From (per person) 1,911
View Trip
12 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (2)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 15 July 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,357
OCEANVIEW
$5,456
BALCONY
$8,307
SUITE
$11,089
From (per person) 5,357
View Trip
9 Day Mind and Taste Buds Awake with the Mucem in the Mediterranean with Ponant
Cruise
 (2)

9 Days (8 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 09 October 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,214
SUITE
$15,486
Save (per person) 156
From (per person) 8,214
View Trip
12 Day Along the Mediterranean Sea with the Mucem with Ponant
Cruise

12 Days (11 Nights) Athens to Lisbon
Cruise Line: Ponant
Ship: L'Austral
Departure: 10 October 2024
Countries Visited: Greece, Sicily, Sardinia
Exclusive Savings
INSIDE
-
OCEANVIEW
$9,806
BALCONY
$10,639
SUITE
-
Save (per person) 184
From (per person) 9,806
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Countries Visited: Malta, Sicily, Italy
From (per person) 18,940
View Trip
16 Day Italian Treasures with Malta - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

16 Days Venice to Valletta
Operated By: Scenic
Ship: Scenic Eclipse II
Departure: 30 May 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$25,879
SUITE
$31,913
Save (per person) 3,261
From (per person) 25,879
View Trip
8 Day Mediterranean with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Valletta to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 25 September 2025
Countries Visited: Malta, Croatia, Sicily
Latest Offer
INSIDE
$2,080
OCEANVIEW
$2,565
BALCONY
$2,979
SUITE
$4,841
From (per person) 2,080
View Trip
8 Day Italian Treasures: Amalfi Coast, Sicily and Malta with Scenic
New ReleaseCruise

8 Days (7 Nights) Rome to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 07 June 2026
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,291
SUITE
$16,325
Save (per person) 3,104
From (per person) 10,291
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Valencia
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 26 April 2025
Countries Visited: Italy, Sicily, Spain
Exclusive Deal
INSIDE
$784
OCEANVIEW
$913
BALCONY
$1,081
SUITE
$1,824
From (per person) 784
View Trip
11 Day Mediterranean Delights with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Valletta to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 20 July 2026
Countries Visited: Malta, Sicily, Tunisia
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,588
BALCONY
-
SUITE
$14,548
Save (per person) 2,607
From (per person) 10,588
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 26 July 2025
Countries Visited: Greece, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$24,339
Save (per person) 1,746
From (per person) 24,339
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+6 more), Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Venus, Viking Vesta
Departures: Oct 2024 to Aug 2026
Countries Visited: Italy, Sicily, Croatia
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$5,935
SUITE
$8,325
Save (per person) 1,090
From (per person) 5,935
View Trip
8 Day Hidden Gems of Italy with Travelmarvel
New ReleaseCruise

8 Days (7 Nights) Valletta to Venice
Operated By: Travelmarvel
Departure: 05 May 2025
Countries Visited: Malta, Sicily, Italy
Exclusive Deal
Save (per person) 1,345
From (per person) 5,150
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 07 June 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,509
Save (per person) 2,096
From (per person) 9,509
View Trip
8 Day Island Odyssey: Malta, Sicily & the Greek Isles with Scenic
New ReleaseCruise

8 Days (7 Nights) Valletta to Athens
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 June 2026
Countries Visited: Malta, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,143
SUITE
$16,177
Save (per person) 3,102
From (per person) 10,143
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 26 October 2024
Countries Visited: Italy, Sicily, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$786
SUITE
-
From (per person) 786
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Valletta to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: May 2026 to Jul 2026
Countries Visited: Malta, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$9,747
BALCONY
-
SUITE
$13,261
Save (per person) 2,102
From (per person) 9,747
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departure: 05 October 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
$2,069
OCEANVIEW
$2,854
BALCONY
$2,936
SUITE
$3,817
Save (per person) 969
From (per person) 2,069
View Trip
11 Day Amalfi Coast, Sicily & Gulf of Naples with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 19 October 2024
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,301
Save (per person) 3,144
From (per person) 14,301
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 29 April 2025
Countries Visited: Spain, Tunisia, Sicily
Exclusive Deal
INSIDE
-
OCEANVIEW
$699
BALCONY
$788
SUITE
$1,114
From (per person) 699
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 11 July 2026
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$9,747
BALCONY
-
SUITE
$13,261
Save (per person) 2,098
From (per person) 9,747
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+4 more), Viking Saturn, Viking Sea, Viking Vela, Viking Vesta
Departures: May 2025 to Sep 2026
Countries Visited: Italy, Croatia, Sicily
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$5,935
SUITE
$10,390
Save (per person) 1,074
From (per person) 5,935
View Trip
8 Day Italian & Aegean Sampler with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 30 April 2026
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$5,178
SUITE
$7,475
Save (per person) 2,042
From (per person) 5,178
View Trip
15 Day Turkey & Greek Isles with Holland America
Cruise
 (2)

15 Days (14 Nights) Athens to Athens
Cruise Line: Holland America
Ship: Nieuw Statendam
Departure: 19 October 2024
Countries Visited: Greece, Turkey, Malta, Sicily
INSIDE
-
OCEANVIEW
$5,288
BALCONY
-
SUITE
-
From (per person) 5,288
View Trip
8 Day Ancient jewels of the Mediterranean with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 18 October 2025
Countries Visited: Malta, Sicily, Italy, Greece
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$7,125
SUITE
$12,750
Save (per person) 135
From (per person) 7,125
View Trip
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