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Sicily Short Break Cruises

Explore Sicily on one of 6 short break cruises, departing from Amalfi, Barcelona, Messina, Palermo and Rome. April, May and October are the most popular months to cruise to Sicily and we have over 6 departures available from one of the world's leading cruise lines specialising in short break cruises.
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4 Days
5 Days
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$619pp
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6 Cruises (6 Cruise Departures)
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 05 May 2026
Visit: Spain, Tunisia, Sicily
Inside
$329
Oceanview
-
Balcony
$499
Suite
-
From
US$329
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Rome to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 27 October 2026
Visit: Italy, Sicily, Greece, Montenegro
Inside
-
Oceanview
$489
Balcony
$669
Suite
$1,119
From
US$489
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 05 May 2026
Visit: Spain, Tunisia, Sicily, Italy
Inside
$619
Oceanview
-
Balcony
-
Suite
-
From
US$619
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Palermo to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 16 October 2026
Visit: Sicily, Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$599
Suite
-
From
US$599
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Messina to Venice
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 01 April 2026
Visit: Sicily, Malta, Croatia, Italy
Inside
$310
Oceanview
-
Balcony
-
Suite
-
From
US$310
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Amalfi to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 21 April 2026
Visit: Italy, Sicily, Tunisia, Spain
Inside
$394
Oceanview
-
Balcony
$615
Suite
$925
From
US$394
Per Person
View Trip
Results: 6 results

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Trip Lengths

10 Day 2 Week 3 Week 7 Day

Departure Months

April May October

Cities

Palermo

Cruise Lines Exploring The Med

APT Med Cruises Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

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