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Sicily Short Break Cruises

Explore Sicily on one of 8 short break cruises, departing from Amalfi, Barcelona, Florence, Genoa, Messina and more. April is the most popular month to cruise to Sicily and we have over 8 departures available from one of the world's leading cruise lines specialising in short break cruises.
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8 Cruises (8 Cruise Departures)
4 Day Mediterranean with MSC Cruises
Cruise
 (3)

4 Days (3 Nights) Genoa to Valletta
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 19 April 2026
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
-
Suite
$1,579
From
US$1,579
Per Person
View Trip
3 Day Mediterranean with MSC Cruises
Cruise
 (3)

3 Days (2 Nights) Rome to Valletta
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 19 January 2026
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$349
Suite
-
From
US$349
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Rome to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 27 October 2026
Visit: Italy, Sicily, Greece, Montenegro
Inside
$379
Oceanview
$489
Balcony
$599
Suite
$1,119
From
US$379
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Amalfi to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 21 April 2026
Visit: Italy, Sicily, Tunisia, Spain
Inside
$515
Oceanview
$605
Balcony
$675
Suite
$985
From
US$515
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 07 February 2026
Visit: Spain, France, Italy, Sicily
Inside
-
Oceanview
-
Balcony
$549
Suite
$869
From
US$549
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Florence to Valletta
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 27 April 2026
Visit: Italy, Sardinia, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$580
Suite
$820
From
US$580
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 05 May 2026
Visit: Spain, Tunisia, Sicily, Italy
Inside
$419
Oceanview
$529
Balcony
$629
Suite
$1,269
From
US$419
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Messina to Venice
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 01 April 2026
Visit: Sicily, Malta, Croatia, Italy
Inside
-
Oceanview
$460
Balcony
-
Suite
-
From
US$460
Per Person
View Trip
Results: 8 results

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