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10 Day Sicily Cruises

Looking to discover the best of Sicily on a 10 day cruise? Then choose from our range of unique cruise itineraries with eleven leading cruise lines that explore Sicily. August is the most popular month to travel to Sicily and we have 44 cruise departures available.
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35 Cruises (44 Cruise Departures)
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Kaia
Departures: May 2027 to Oct 2027
Visit: Italy, Sicily, Malta
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$7,900
Balcony
-
Suite
$10,679
From
US$7,900
Save 1,447
Per Person
View Trip
10 Day Authentic Mediterranean shores with Ponant
Cruise
 (2)

10 Days (9 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 October 2026
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
$8,510
Balcony
$8,980
Suite
$18,710
From
US$8,510
Per Person
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Valletta to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 05 May 2026
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$11,650
From
US$11,650
Per Person
View Trip
10 Day Mysteries Of History with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 24 May 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,699
Oceanview
$2,949
Balcony
$4,499
Suite
$6,399
From
US$2,699
Save 2,699
Per Person
View Trip
10 Day Sicily, Naples, Cannes & More with Virgin Voyages
Cruise
 (1)

10 Days (9 Nights) Rome to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 22 August 2026
Visit: Italy, Sicily, Corsica, France
Inside
$1,521
Oceanview
$1,881
Balcony
$2,061
Suite
$4,401
From
US$1,521
Per Person
View Trip
10 Day Trojan Trek Revisited with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 July 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,899
Oceanview
$3,149
Balcony
$4,799
Suite
$6,699
From
US$2,899
Save 2,899
Per Person
View Trip
10 Day Exploring Ancient Empires with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 29 March 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Inclusions
Exclusive Savings
Inside
$2,399
Oceanview
$2,649
Balcony
$4,199
Suite
$6,099
From
US$2,399
Save 2,399
Per Person
View Trip
10 Day Italy & Greece Cruise: Amalfi, Crete & Santorini with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 August 2027
Visit: Italy, Sicily, Greece, Turkey
Azamara Always Included
Inside
$4,149
Oceanview
$4,699
Balcony
$5,749
Suite
$8,399
From
US$4,149
Per Person
View Trip
10 Day Civitavecchia (Rome) to Athens (Piraeus) with Silversea
Cruise
 (1)

10 Days (9 Nights) Rome to Athens
Cruise Line: Silversea
Ship: Silver Nova
Departure: 16 April 2027
Visit: Italy, Sicily, Malta, Greece
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,100
Suite
$11,200
From
US$7,100
Save 1,500
Per Person
View Trip
10 Day Italy & Greece Cruise with Celebrity Cruises
Cruise
 (3)

10 Days (9 Nights) Barcelona to Athens
Cruise Line: Celebrity Cruises
Ship: Celebrity Infinity
Departure: 01 April 2028
Visit: Spain, Italy, Sicily, Greece
Exclusive Savings
Inside
$1,482
Oceanview
$1,722
Balcony
$2,217
Suite
$4,677
From
US$1,736
Save 557
Per Person
View Trip
10 Day From Croatia to the Amalfi Coast via Sicily with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Dubrovnik to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departures: May 2027 to Oct 2027
Visit: Croatia, Italy, Greece, Sicily
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$6,798
Balcony
-
Suite
$9,431
From
US$6,798
Save 1,747
Per Person
View Trip
10 Day Nice to Nice with Silversea
Cruise

10 Days (9 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 06 July 2027
Visit: France, Italy, Sicily, Malta
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$5,900
Balcony
$6,600
Suite
$9,800
From
US$5,900
Save 2,500
Per Person
View Trip
10 Day A Journey Through The Artistic And Historic Spirit Of Mediterranean Coastal Beauty with Explora Journeys
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 12 October 2026
Visit: Spain, France, Italy, Sicily
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$7,245
From
US$7,245
Per Person
View Trip
10 Day Greece & Italy Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Mariner of the Seas
Departure: 28 August 2027
Visit: Italy, Greece, Sicily, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,641
Oceanview
$2,110
Balcony
$2,528
Suite
$4,138
From
US$2,205
Save 50
Per Person
View Trip
10 Day From the Iberian Shores to the Italian Coast with Ponant
Cruise

10 Days (9 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 04 April 2027
Visit: Spain, Sicily, Italy, Malta
Inside
-
Oceanview
-
Balcony
$7,320
Suite
$13,610
From
US$7,320
Per Person
View Trip
10 Day Best Of Italy & Croatia Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) Bologna to Barcelona
Cruise Line: Royal Caribbean
Ship: Mariner of the Seas
Departure: 15 June 2027
Visit: Italy, Croatia, Sicily, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,404
Oceanview
$1,784
Balcony
$2,131
Suite
$3,501
From
US$1,865
Save 50
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 22 July 2026
Visit: Italy, Sicily, Malta, Greece, Turkey
Inside
$2,009
Oceanview
$2,139
Balcony
$2,509
Suite
$3,609
From
US$2,009
Per Person
View Trip
10 Day Ancient Shores of the Mediterranean with Ponant
Cruise
 (2)

10 Days (9 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 05 May 2026
Visit: Spain, Algeria, Tunisia, Sicily, Malta
Inside
-
Oceanview
$8,120
Balcony
$8,560
Suite
$16,050
From
US$8,120
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 27 May 2026
Visit: Italy, Sicily, Malta, Greece, Turkey
Inside
$1,109
Oceanview
$1,259
Balcony
$1,609
Suite
$2,509
From
US$1,109
Per Person
View Trip
10 Day Mediterranean: Athens to Rome with Virgin Voyages
Cruise
 (1)

10 Days (9 Nights) Athens to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 29 August 2027
Visit: Greece, Turkey, Malta, Sicily, Italy
Inside
$1,811
Oceanview
$1,971
Balcony
$2,151
Suite
$6,074
From
US$1,811
Per Person
View Trip
10 Day Western Med: Barcelona to Rome with Virgin Voyages
Cruise
 (5)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 08 August 2027
Visit: Spain, France, Italy, Sicily, Malta
Inside
$2,407
Oceanview
$2,705
Balcony
$2,875
Suite
-
From
US$2,407
Per Person
View Trip
10 Day A Journey To Spain's Icons & North Africa's Sunlit Shores with Explora Journeys
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 February 2027
Visit: Italy, Sicily, Tunisia, Algeria, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$4,865
From
US$4,865
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 13 July 2026
Visit: Turkey, Greece, Malta, Sicily, Italy
Inside
$2,049
Oceanview
$2,199
Balcony
$2,669
Suite
$3,619
From
US$2,049
Per Person
View Trip
10 Day Italian Shores and Isle of Beauty with Ponant
Cruise
 (2)

10 Days (9 Nights) Valletta to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 June 2027
Visit: Malta, Sicily, Italy, Corsica, France
Inside
-
Oceanview
$7,090
Balcony
$7,470
Suite
$13,900
From
US$7,090
Per Person
View Trip
10 Day Alluring Ancient Ruins with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 15 May 2027
Visit: Turkey, Greece, Sicily, Italy, Sardinia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,799
Oceanview
$2,949
Balcony
$4,499
Suite
$6,399
From
US$2,799
Save 2,799
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departures: Jul 2027 to Aug 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
Inside
$2,249
Oceanview
$2,759
Balcony
$3,229
Suite
$4,149
From
US$2,249
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 18 May 2026
Visit: Turkey, Greece, Malta, Sicily, Italy
Inside
$1,199
Oceanview
$1,349
Balcony
$1,699
Suite
$2,649
From
US$1,199
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departures: Sep 2026 to Aug 2027
Visit: Turkey, Greece, Malta, Sicily, Italy
Inside
$2,589
Oceanview
$2,769
Balcony
$3,089
Suite
$4,119
From
US$2,589
Per Person
View Trip
10 Day Medieval Mediterranean with Oceania Cruises
Cruise

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 19 February 2028
Visit: Turkey, Greece, Malta, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,699
Suite
$5,299
From
US$2,699
Save 2,699
Per Person
View Trip
10 Day Eclipse The Ordinary with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 29 July 2027
Visit: Spain, Malta, Sicily, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$69,999
From
US$69,999
Save 69,999
Per Person
View Trip
Results: 1-30 of 35

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