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Sicily Cruises Starting In September 2026, 2027 and 2028

If you're looking at joining a cruise to Sicily in September 2026, 2027 or 2028, we have 89 unique cruise itineraries and 1,421 departures available, operated by seventeen of the world's leading cruise lines departing in September.
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89 Cruises (1,421 Cruise Departures)
11 Day Made in Italy, the Luxury Edition with Ponant
Cruise
 (2)

11 Days (10 Nights) Florence to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 08 September 2027
Visit: Italy, Sicily
Inside
-
Oceanview
$16,120
Balcony
$17,010
Suite
$32,020
From
US$16,120
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: May 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$4,999
From
US$3,799
Save 900
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Jun 2026 to Jul 2028
Visit: Italy, Sicily, Croatia
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$4,999
From
US$3,599
Save 800
Per Person
View Trip
9 Day Tribute to Maria Callas with Ponant
Cruise
 (2)

9 Days (8 Nights) Athens to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 29 September 2027
Visit: Greece, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$9,230
Suite
$16,470
From
US$9,230
Per Person
View Trip
12 Day Adriatic, Sicily & the Amalfi Coast with Scenic
New ReleaseCruise

12 Days (11 Nights) Venice to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departures: Jun 2028 to Sep 2028
Visit: Italy, Croatia, Sicily
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,673
Suite
$18,234
From
US$15,673
Save 2,322
Per Person
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Tour + Cruise

12 Days Malta to Rome
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: May 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$12,990
Suite
$16,990
From
US$12,990
Per Person
View Trip
11 Day 5th Opera Festival at Sea with Ponant
Cruise

11 Days (10 Nights) Venice to Nice
Cruise Line: Ponant
Ships: Le Boreal, Le Bougainville, Le Dumont d’Urville
Departures: Jun 2026 to Sep 2027
Visit: Italy, Sicily, France
Inside
-
Oceanview
$7,870
Balcony
$8,290
Suite
$15,440
From
US$7,870
Per Person
View Trip
12 Day Rome, the Amalfi Coast & Sicily with Tauck
Tour + Cruise

12 Days Rome to Malta
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$12,490
Suite
$16,490
From
US$12,490
Per Person
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Athens
Cruise Line: Royal Caribbean
Ships: Brilliance of the Seas, Explorer of the Seas
Departures: May 2026 to Sep 2027
Visit: Italy, Sicily, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$999
Oceanview
$1,169
Balcony
$1,840
Suite
$2,878
From
US$999
Save 994
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Italy, Sicily, Spain, France
Inside
$771
Oceanview
$861
Balcony
$1,041
Suite
-
From
US$771
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Italy, Sicily, Spain, France
Drinks & WiFi Package
Inside
$1,078
Oceanview
$1,218
Balcony
$1,308
Suite
$1,868
From
US$1,078
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2026 to Nov 2026
Visit: Spain, France, Italy, Sicily
Inside
$1,099
Oceanview
$1,040
Balcony
$1,240
Suite
$1,740
From
US$1,040
Per Person
View Trip
11 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (1)

11 Days (10 Nights) Athens to Istanbul
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 04 September 2027
Visit: Greece, Sicily, Malta, Turkey
Princess Standard
Inside
$2,125
Oceanview
-
Balcony
$2,624
Suite
$3,050
From
US$2,125
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Sep 2027
Visit: Spain, France, Italy, Sicily
Inside
$579
Oceanview
-
Balcony
$779
Suite
$1,099
From
US$579
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$834
Oceanview
$924
Balcony
$1,104
Suite
-
From
US$834
Per Person
View Trip
8 Day Mediterranean Marvels Of Pompeii With History Channel with Holland America
Cruise
 (3)

8 Days (7 Nights) Athens to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departures: Jul 2026 to Sep 2027
Visit: Greece, Montenegro, Sicily, Italy
Fare Saver
Book Early & Have It All Fare Option
Inside
$774
Oceanview
$824
Balcony
$1,124
Suite
$1,674
From
US$774
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$569
Oceanview
$1,739
Balcony
$849
Suite
$1,099
From
US$569
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Sicily, Spain, France, Italy
Inside
$861
Oceanview
$921
Balcony
$1,061
Suite
-
From
US$861
Per Person
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 September 2026
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Inside
$1,539
Oceanview
$1,669
Balcony
$1,879
Suite
$5,649
From
US$1,539
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Virgin Voyages
Cruise
 (5)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departures: May 2027 to Sep 2027
Visit: Spain, France, Italy, Sicily
Inside
$1,323
Oceanview
$1,673
Balcony
$1,743
Suite
$4,200
From
US$1,323
Per Person
View Trip
15 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 21 September 2026
Visit: Italy, Sicily, Greece, Turkey
Bonus Onboard Credit
Inside
$2,739
Oceanview
$2,909
Balcony
$3,569
Suite
$6,229
From
US$2,739
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 20 September 2026
Visit: Spain, France, Italy, Sicily
Inside
$1,099
Oceanview
-
Balcony
$1,669
Suite
$1,899
From
US$1,099
Per Person
View Trip
8 Day Mediterranean with Greece & Adriatic with Princess
Cruise
 (7)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: May 2026 to Oct 2027
Visit: Greece, Montenegro, Sicily, Spain
Princess Standard
Princess Premier
Sanctuary Collection
Inside
$1,089
Oceanview
$1,329
Balcony
$1,694
Suite
$1,869
From
US$1,089
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Sicily, Spain, France, Italy
Drinks & WiFi Package
Inside
$897
Oceanview
$1,067
Balcony
$1,237
Suite
$1,747
From
US$897
Per Person
View Trip
11 Day Best Of Italy & Greece Cruise with Celebrity Cruises
Cruise
 (2)

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 10 September 2027
Visit: Spain, Italy, Sicily, Greece
Exclusive Savings
Inside
$1,920
Oceanview
$2,490
Balcony
$2,159
Suite
$7,961
From
US$2,247
Save 705
Per Person
View Trip
8 Day Greece, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 17 September 2027
Visit: Italy, Croatia, Greece, Sicily
Bonus Onboard Credit
Inside
$1,249
Oceanview
$1,339
Balcony
$1,439
Suite
$3,039
From
US$1,249
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2027
Visit: Italy, Sicily, France, Spain
Inside
$559
Oceanview
$1,519
Balcony
$739
Suite
$949
From
US$559
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Italy, Sicily, Spain, France
Drinks & WiFi Package
Inside
$1,049
Oceanview
$1,169
Balcony
$1,329
Suite
$1,839
From
US$1,049
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Italy, Sicily, Spain, France
Inside
$846
Oceanview
$876
Balcony
$1,056
Suite
-
From
US$846
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy
Bonus Onboard Credit
Inside
$1,359
Oceanview
$1,409
Balcony
$1,779
Suite
-
From
US$1,359
Per Person
View Trip
Results: 1-30 of 89

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