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Sicily Cruises Starting In September 2026, 2027 and 2028

If you're looking at joining a cruise to Sicily in September 2026, 2027 or 2028, we have 86 unique cruise itineraries and 1,415 departures available, operated by seventeen of the world's leading cruise lines departing in September.
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86 Cruises (1,415 Cruise Departures)
11 Day Made in Italy, the Luxury Edition with Ponant
Cruise
 (1)

11 Days (10 Nights) Florence to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 08 September 2027
Visit: Italy, Sicily
Inside
-
Oceanview
$16,120
Balcony
$17,010
Suite
$32,020
From
US$16,120
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,949
Suite
$5,499
From
US$3,949
Save 800
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Mar 2026 to Jul 2028
Visit: Italy, Sicily, Croatia
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,899
Suite
$5,499
From
US$3,899
Save 300
Per Person
View Trip
11 Day 5th Opera Festival at Sea with Ponant
Cruise
 (1)

11 Days (10 Nights) Venice to Nice
Cruise Line: Ponant
Ships: Le Boreal, Le Bougainville
Departures: Jun 2027 to Sep 2027
Visit: Italy, Sicily, France
Inside
-
Oceanview
$7,870
Balcony
$8,290
Suite
$15,440
From
US$7,870
Per Person
View Trip
8 Day Fusina (Venice) to Monte Carlo with Silversea
Cruise

8 Days (7 Nights) Venice to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 September 2027
Visit: Italy, Croatia, Sicily, Monaco
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,180
Suite
$9,780
From
US$5,180
Save 2,220
Per Person
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Tour + Cruise

12 Days Malta to Rome
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$12,490
Suite
$16,490
From
US$12,490
Per Person
View Trip
12 Day Rome, the Amalfi Coast & Sicily with Tauck
Tour + Cruise

12 Days Rome to Malta
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$12,490
Suite
$16,490
From
US$12,490
Per Person
View Trip
12 Day Adriatic, Sicily & the Amalfi Coast with Scenic
New ReleaseCruise

12 Days (11 Nights) Venice to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departures: Jun 2028 to Sep 2028
Visit: Italy, Croatia, Sicily
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,016
Suite
$19,150
From
US$17,016
Save 18,875
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Italy, Sicily, Spain, France
Bonus Onboard Credit
Inside
$875
Oceanview
$1,045
Balcony
$1,205
Suite
$1,805
From
US$875
Per Person
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 September 2026
Visit: Turkey, Greece, Sicily, Italy
Inside
$1,529
Oceanview
$1,659
Balcony
$1,919
Suite
-
From
US$1,529
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy, Sicily
Bonus Onboard Credit
Inside
$863
Oceanview
$963
Balcony
$1,133
Suite
-
From
US$863
Per Person
View Trip
11 Day Best Of Italy & Greece Cruise with Celebrity Cruises
Cruise
 (2)

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 10 September 2027
Visit: Spain, Italy, Sicily, Greece
Bonus Onboard Credit
Exclusive Savings
Inside
$2,095
Oceanview
$2,577
Balcony
$2,931
Suite
$5,792
From
US$2,095
Save 1,057
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: France, Italy, Sicily, Spain
Bonus Onboard Credit
Inside
$761
Oceanview
$861
Balcony
$1,031
Suite
-
From
US$761
Per Person
View Trip
8 Day Mediterranean with Greece & Adriatic with Princess
Cruise
 (6)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Mar 2026 to Oct 2027
Visit: Greece, Montenegro, Sicily, Spain
Princess Standard
Princess Premier
Sanctuary Collection
Inside
$1,134
Oceanview
$1,344
Balcony
$1,519
Suite
$1,869
From
US$1,134
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$979
Oceanview
$1,579
Balcony
$1,469
Suite
$1,739
From
US$979
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Sep 2027
Visit: Spain, France, Italy, Sicily
Inside
$999
Oceanview
$1,729
Balcony
$1,449
Suite
$1,639
From
US$999
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Sicily, Spain, France, Italy
Bonus Onboard Credit
Inside
$837
Oceanview
$1,007
Balcony
$1,167
Suite
$1,667
From
US$837
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Italy, Sicily, Spain, France
Bonus Onboard Credit
Inside
$800
Oceanview
$900
Balcony
$1,070
Suite
-
From
US$800
Per Person
View Trip
17 Day Discover the Adriatic from Venice to Rome with Emerald Cruises
New ReleaseCruise

17 Days (16 Nights) Venice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 04 September 2027
Visit: Italy, Croatia, Greece, Sicily
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
$16,738
Balcony
-
Suite
$21,782
From
US$16,738
Save 17,742
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Italy, Sicily, Spain, France
Bonus Onboard Credit
Inside
$811
Oceanview
$911
Balcony
$1,081
Suite
-
From
US$811
Per Person
View Trip
11 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (1)

11 Days (10 Nights) Athens to Istanbul
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 04 September 2027
Visit: Greece, Sicily, Malta, Turkey
Princess Standard
Inside
$2,250
Oceanview
-
Balcony
$2,429
Suite
$3,148
From
US$2,250
Per Person
View Trip
12 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departures: Jul 2026 to Sep 2026
Visit: Italy, Sicily, Croatia, Montenegro
Bonus Onboard Credit
Exclusive Savings
Inside
$2,149
Oceanview
$2,499
Balcony
$2,674
Suite
$6,379
From
US$3,227
Save 91
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2027
Visit: Italy, Sicily, France, Spain
Inside
$869
Oceanview
$1,339
Balcony
$1,289
Suite
$1,479
From
US$869
Per Person
View Trip
11 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departures: Jun 2027 to Oct 2027
Visit: Italy, Sicily, Montenegro, Croatia
Bonus Onboard Credit
Exclusive Savings
Inside
$1,860
Oceanview
$2,017
Balcony
$2,312
Suite
$6,189
From
US$2,827
Save 76
Per Person
View Trip
15 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 21 September 2026
Visit: Italy, Sicily, Greece, Turkey
Inside
$2,969
Oceanview
$3,249
Balcony
$3,839
Suite
$6,965
From
US$2,969
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2026 to Nov 2026
Visit: Spain, France, Italy, Sicily
Bonus Onboard Credit
Inside
$854
Oceanview
$935
Balcony
$1,125
Suite
$1,635
From
US$854
Per Person
View Trip
8 Day Croatia, Montenegro & Italy with Seabourn
Cruise

8 Days (7 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,029
Suite
$8,760
From
US$5,029
Save 87
Per Person
View Trip
12 Day Italy Intensive Cruise: Florence, Sorrento & Sicily with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 September 2027
Visit: France, Italy, Sicily, Montenegro
Azamara Always Included
Exclusive Savings
Inside
$3,796
Oceanview
$4,242
Balcony
$5,096
Suite
$7,298
From
US$3,796
Save 93
Per Person
View Trip
8 Day Croatian Culture & Cuisine with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 09 September 2027
Visit: Italy, Sicily, Montenegro, Croatia
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,483
Suite
$7,071
From
US$6,483
Save 11,715
Per Person
View Trip
11 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 16 September 2026
Visit: Italy, Sicily, Greece, Turkey
Exclusive Savings
Inside
$3,073
Oceanview
$3,732
Balcony
$3,917
Suite
$5,323
From
US$3,073
Save 86
Per Person
View Trip
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