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Sicily Cruises Starting In October 2026 and 2027

If you're looking at joining a cruise to Sicily in October 2026 or 2027, we have 107 unique cruise itineraries and 1,663 departures available, operated by seventeen of the world's leading cruise lines departing in October.
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107 Cruises (1,663 Cruise Departures)
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,949
Suite
$5,499
From
US$3,949
Save 800
Per Person
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Kaia
Departures: May 2027 to Oct 2027
Visit: Italy, Sicily, Malta
Wave Offer
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$7,098
Balcony
-
Suite
$9,935
From
US$7,098
Save 11,248
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Mar 2026 to Jul 2028
Visit: Italy, Sicily, Croatia
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,899
Suite
$5,499
From
US$3,899
Save 300
Per Person
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departures: Oct 2026 to Oct 2026
Visit: Italy, Sicily, Greece
Bonus Onboard Credit
Exclusive Savings
Inside
$1,264
Oceanview
$1,554
Balcony
$1,576
Suite
$2,676
From
US$1,264
Save 680
Per Person
View Trip
10 Day Authentic Mediterranean shores with Ponant
Cruise
 (1)

10 Days (9 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 October 2026
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
$8,120
Balcony
$8,560
Suite
$17,810
From
US$8,120
Per Person
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Tour + Cruise

12 Days Malta to Rome
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$12,490
Suite
$16,490
From
US$12,490
Per Person
View Trip
12 Day Rome, the Amalfi Coast & Sicily with Tauck
Tour + Cruise

12 Days Rome to Malta
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$12,490
Suite
$16,490
From
US$12,490
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Italy, Sicily, Spain, France
Bonus Onboard Credit
Inside
$875
Oceanview
$1,045
Balcony
$1,205
Suite
$1,805
From
US$875
Per Person
View Trip
11 Day Havens Of Italy & Spain with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Monte Carlo to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 October 2026
Visit: Monaco, Italy, Sardinia, Sicily, Spain
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,400
Oceanview
$2,584
Balcony
$3,981
Suite
$5,533
From
US$2,400
Save 3,598
Per Person
View Trip
11 Day Monte Carlo to Rome with Silversea
Cruise

11 Days (10 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 08 October 2026
Visit: Monaco, France, Corsica, Italy, Sicily
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,560
Suite
$11,890
From
US$7,560
Save 3,240
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy, Sicily
Bonus Onboard Credit
Inside
$863
Oceanview
$963
Balcony
$1,133
Suite
-
From
US$863
Per Person
View Trip
15 Day Ancient Mediterranean Antiquities with Viking Cruises
Cruise
 (6)

15 Days (14 Nights) Rome to Istanbul
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mira (+5 more), Viking Neptune, Viking Saturn, Viking Star, Viking Vela, Viking Vesta
Departures: Apr 2026 to Feb 2028
Visit: Italy, Sicily, Greece, Turkey
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$5,198
Suite
$7,198
From
US$5,198
Save 1,300
Per Person
View Trip
8 Day Journey to Antiquities with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Athens to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Libra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: May 2026 to Apr 2028
Visit: Greece, Turkey, Sicily, Italy
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,499
From
US$2,599
Save 300
Per Person
View Trip
8 Day Italy, Croatia & Malta Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Bologna
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 19 October 2026
Visit: Italy, Sicily, Malta, Croatia
Bonus Onboard Credit
Exclusive Savings
Inside
$1,196
Oceanview
$1,357
Balcony
$1,869
Suite
$4,711
From
US$1,196
Save 601
Per Person
View Trip
11 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (1)

11 Days (10 Nights) Athens to Istanbul
Cruise Line: Princess
Ship: Enchanted Princess
Departures: May 2027 to Oct 2027
Visit: Greece, Sicily, Malta, Turkey
Princess Standard
Inside
$1,730
Oceanview
$2,809
Balcony
$2,025
Suite
$2,430
From
US$1,730
Per Person
View Trip
8 Day Greece, Italy And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 22 October 2027
Visit: Italy, Greece, Sicily, Spain
Inside
$1,399
Oceanview
$1,599
Balcony
$1,899
Suite
$4,049
From
US$1,399
Per Person
View Trip
8 Day Spotlight On Sparkling Wines with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 October 2026
Visit: Italy, Sicily, Malta, Croatia
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,709
Suite
$7,954
From
US$7,709
Save 12,389
Per Person
View Trip
8 Day Greece, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia
Inside
$1,409
Oceanview
$1,609
Balcony
$1,909
Suite
$4,059
From
US$1,409
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: France, Italy, Sicily, Spain
Bonus Onboard Credit
Inside
$761
Oceanview
$861
Balcony
$1,031
Suite
-
From
US$761
Per Person
View Trip
8 Day Italy & Croatia Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Bologna to Rome
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 30 October 2027
Visit: Italy, Croatia, Montenegro, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,090
Oceanview
$1,260
Balcony
$1,560
Suite
$2,119
From
US$1,090
Save 546
Per Person
View Trip
8 Day Mediterranean with Greece & Adriatic with Princess
Cruise
 (6)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Mar 2026 to Oct 2027
Visit: Greece, Montenegro, Sicily, Spain
Princess Standard
Princess Premier
Sanctuary Collection
Inside
$1,134
Oceanview
$1,344
Balcony
$1,519
Suite
$1,869
From
US$1,134
Per Person
View Trip
15 Day Mediterranean & Adriatic Odyssey with Viking Cruises
New ReleaseCruise
 (5)

15 Days (14 Nights) Athens to Rome
Cruise Line: Viking Cruises
Ships: Viking Mira, Viking Saturn (+2 more), Viking Sea, Viking Star
Departures: Oct 2026 to Mar 2028
Visit: Greece, Croatia, Italy, Sicily
Viking $999 Air Deal
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,999
Suite
$9,999
From
US$5,999
Save 1,000
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Rome to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 27 October 2026
Visit: Italy, Sicily, Greece, Montenegro
Inside
$379
Oceanview
$489
Balcony
$599
Suite
$1,119
From
US$379
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$979
Oceanview
$1,579
Balcony
$1,469
Suite
$1,739
From
US$979
Per Person
View Trip
8 Day Greece And Turkey with Cunard
Cruise
 (13)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy
Inside
$1,319
Oceanview
$1,429
Balcony
$1,579
Suite
$3,279
From
US$1,319
Per Person
View Trip
11 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 13 October 2027
Visit: Turkey, Greece, Sicily, Italy
Exclusive Savings
Inside
$2,454
Oceanview
$2,988
Balcony
$3,783
Suite
$4,617
From
US$2,454
Save 65
Per Person
View Trip
8 Day Ionian Exploration with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 October 2027
Visit: Greece, Turkey, Sicily, Italy
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$4,491
From
US$2,599
Save 2,599
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Sicily, Spain, France, Italy
Bonus Onboard Credit
Inside
$837
Oceanview
$1,007
Balcony
$1,167
Suite
$1,667
From
US$837
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Italy, Sicily, Spain, France
Bonus Onboard Credit
Inside
$800
Oceanview
$900
Balcony
$1,070
Suite
-
From
US$800
Per Person
View Trip
8 Day Mykonos Moons and Italian Sunrises with Virgin Voyages
Cruise
 (1)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 04 October 2026
Visit: Greece, Sicily, Italy, Spain
With Love From the World
Inside
-
Oceanview
$2,043
Balcony
$2,341
Suite
$3,983
From
US$2,043
Per Person
View Trip
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