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Sicily Cruises Starting In October 2026 and 2027

If you're looking at joining a cruise to Sicily in October 2026 or 2027, we have 113 unique cruise itineraries and 1,779 departures available, operated by seventeen of the world's leading cruise lines departing in October.
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113 Cruises (1,779 Cruise Departures)
8 Day Italian Sojourn with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$4,999
From
US$3,599
Save 800
Per Person
View Trip
11 Day Ancient Civilisations, from Italy to Greece with Ponant
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Champlain
Departure: 01 October 2026
Visit: Italy, Sicily, Greece
Inside
-
Oceanview
-
Balcony
$10,400
Suite
$18,590
From
US$10,400
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (2)

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Mar 2026 to Jul 2028
Visit: Italy, Sicily, Croatia
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$4,999
From
US$3,599
Save 800
Per Person
View Trip
10 Day Authentic Mediterranean shores with Ponant
Cruise
 (2)

10 Days (9 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 October 2026
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
$8,510
Balcony
$8,560
Suite
$18,710
From
US$8,510
Per Person
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Kaia
Departures: May 2027 to Oct 2027
Visit: Italy, Sicily, Malta
Preferred Plus Fare + Air Credit
Select Fare
Exclusive Savings
Inside
-
Oceanview
$8,175
Balcony
-
Suite
$10,870
From
US$8,175
Save 702
Per Person
View Trip
12 Day Rome, the Amalfi Coast & Sicily with Tauck
Tour + Cruise

12 Days Rome to Malta
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$12,490
Suite
$16,490
From
US$12,490
Per Person
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departures: Oct 2026 to Oct 2026
Visit: Italy, Sicily, Greece
Exclusive Savings
Inside
$1,854
Oceanview
$2,184
Balcony
$2,597
Suite
$4,337
From
US$1,854
Save 951
Per Person
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Tour + Cruise

12 Days Malta to Rome
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$12,490
Suite
$16,490
From
US$12,490
Per Person
View Trip
8 Day Majestic Medieval Fortresses with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 15 October 2027
Visit: Italy, Croatia, Greece, Sicily
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$1,899
Oceanview
$2,049
Balcony
$3,226
Suite
$4,778
From
US$1,899
Save 1,899
Per Person
View Trip
8 Day Ionian Exploration with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 October 2027
Visit: Greece, Turkey, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$4,491
From
US$2,599
Save 2,599
Per Person
View Trip
11 Day Monte Carlo to Rome with Silversea
Cruise

11 Days (10 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 08 October 2026
Visit: Monaco, France, Corsica, Italy, Sicily
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,380
Suite
$24,920
From
US$9,380
Save 4,020
Per Person
View Trip
9 Day Ancient Cities of the Mediterranean with Ponant
Cruise

9 Days (8 Nights) Athens to Valletta
Cruise Line: Ponant
Ships: Le Champlain, Le Dumont d’Urville
Departures: Nov 2026 to Oct 2027
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$7,110
Suite
$12,620
From
US$7,110
Per Person
View Trip
10 Day From Croatia to the Amalfi Coast via Sicily with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Dubrovnik to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departures: May 2027 to Oct 2027
Visit: Croatia, Italy, Greece, Sicily
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
$7,596
Balcony
-
Suite
$10,150
From
US$7,596
Save 952
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Rome to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 27 October 2026
Visit: Italy, Sicily, Greece, Montenegro
Inside
-
Oceanview
$489
Balcony
$669
Suite
$1,119
From
US$489
Per Person
View Trip
11 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Bologna to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departures: Jun 2026 to Oct 2026
Visit: Italy, Croatia, Montenegro, Sicily
Exclusive Savings
Inside
$1,624
Oceanview
$1,854
Balcony
$2,774
Suite
$5,254
From
US$1,624
Save 1,266
Per Person
View Trip
15 Day Ancient Mediterranean Antiquities with Viking Cruises
Cruise
 (6)

15 Days (14 Nights) Istanbul to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+7 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Nov 2026 to Apr 2028
Visit: Turkey, Greece, Sicily, Italy
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$5,098
Suite
$6,998
From
US$5,098
Save 2,100
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: France, Italy, Sicily, Spain
Inside
$1,010
Oceanview
$1,050
Balcony
$1,240
Suite
$1,690
From
US$1,010
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Italy, Sicily, Spain, France
Exclusive Savings
Inside
$1,019
Oceanview
$1,149
Balcony
$1,319
Suite
$1,769
From
US$1,019
Save 59
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Italy, Sicily, Spain, France
Inside
$831
Oceanview
$931
Balcony
$1,111
Suite
-
From
US$831
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2026 to Nov 2026
Visit: Spain, France, Italy, Sicily
Inside
$860
Oceanview
$1,100
Balcony
$1,260
Suite
$1,740
From
US$860
Per Person
View Trip
11 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (1)

11 Days (10 Nights) Athens to Istanbul
Cruise Line: Princess
Ship: Enchanted Princess
Departures: May 2027 to Oct 2027
Visit: Greece, Sicily, Malta, Turkey
Princess Standard
Inside
$1,525
Oceanview
$2,894
Balcony
$1,825
Suite
$2,280
From
US$1,525
Per Person
View Trip
8 Day Greece And Turkey with Cunard
Cruise
 (13)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Inside
$1,319
Oceanview
$1,429
Balcony
$1,549
Suite
$3,229
From
US$1,319
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Sicily, Spain, France, Italy
Exclusive Savings
Inside
$1,000
Oceanview
$1,110
Balcony
$1,240
Suite
$1,690
From
US$1,000
Save 53
Per Person
View Trip
12 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departures: Jun 2026 to Oct 2026
Visit: Italy, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
$1,774
Oceanview
$1,849
Balcony
$3,024
Suite
$3,981
From
US$1,774
Save 1,325
Per Person
View Trip
8 Day Italy & Croatia Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Bologna to Rome
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 30 October 2027
Visit: Italy, Croatia, Montenegro, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,090
Oceanview
$1,260
Balcony
$1,600
Suite
$2,169
From
US$1,090
Save 546
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2027
Visit: Italy, Sicily, France, Spain
Inside
$789
Oceanview
$1,039
Balcony
$1,059
Suite
$1,259
From
US$789
Per Person
View Trip
8 Day Mediterranean with Greece & Adriatic with Princess
Cruise
 (6)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Mar 2026 to Oct 2027
Visit: Greece, Montenegro, Sicily, Spain
Princess Standard
Sanctuary Collection
Princess Premier
Exclusive Savings
Inside
$1,059
Oceanview
$1,379
Balcony
$1,654
Suite
$1,929
From
US$1,059
Save 71
Per Person
View Trip
12 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Bologna to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 18 October 2027
Visit: Italy, Croatia, Montenegro, Sicily
Exclusive Savings
Inside
$1,960
Oceanview
$2,155
Balcony
$2,255
Suite
$6,724
From
US$1,960
Save 1,124
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$883
Oceanview
$983
Balcony
$1,163
Suite
-
From
US$883
Per Person
View Trip
11 Day Enchanting Greece & the Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

11 Days (10 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 17 October 2026
Visit: Greece, Sicily, Malta, Italy
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,449
From
US$11,449
Save 896
Per Person
View Trip
Results: 1-30 of 113

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