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Sicily Cruises Starting In May 2027 and 2028

If you're looking at joining a cruise to Sicily in May 2027 or 2028, we have 72 unique cruise itineraries and 1,213 departures available, operated by eighteen of the world's leading cruise lines departing in May.
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72 Cruises (1,213 Cruise Departures)
8 Day Italian Sojourn with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+9 more), Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Sep 2026 to Sep 2028
Visit: Italy, Croatia, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$4,999
From
US$3,599
Save 1,000
Per Person
View Trip
9 Day Legendary Shores of Italy and Croatia with Ponant
Cruise
 (2)

9 Days (8 Nights) Rome to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 12 May 2027
Visit: Italy, Sicily, Croatia
Inside
-
Oceanview
$6,650
Balcony
$7,010
Suite
$13,080
From
US$6,650
Per Person
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Sep 2026 to Jul 2028
Visit: Italy, Sicily, Croatia
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$4,999
From
US$3,599
Save 1,200
Per Person
View Trip
12 Day Italy Intensive Cruise: Bologna, Sicily & Amalfi with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Venice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 May 2027
Visit: Italy, Montenegro, Sicily
Azamara Always Included
Inside
$3,939
Oceanview
$4,529
Balcony
$7,319
Suite
$9,479
From
US$3,939
Per Person
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Kaia
Departures: May 2027 to Oct 2027
Visit: Italy, Sicily, Malta
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$7,400
Balcony
-
Suite
$10,179
From
US$7,400
Save 1,895
Per Person
View Trip
9 Day Legendary Shores of Italy and Croatia with Ponant
Cruise
 (2)

9 Days (8 Nights) Venice to Rome
Cruise Line: Ponant
Ship: Le Boreal
Departure: 20 May 2027
Visit: Italy, Croatia, Sicily
Inside
-
Oceanview
$6,300
Balcony
$6,630
Suite
$12,350
From
US$6,300
Per Person
View Trip
11 Day Italy Intensive Cruise: Venice, Sicily & Amalfi with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Venice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 05 May 2027
Visit: Italy, Montenegro, Sicily
Azamara Always Included
Inside
$3,549
Oceanview
$4,089
Balcony
$5,339
Suite
$8,149
From
US$3,549
Per Person
View Trip
13 or 12 Day The Amalfi, Sicily and Malta: The Godfather with Aurora Expeditions
New ReleaseCruise

13 or 12 Days Rome to Valletta
Cruise Line: Aurora Expeditions
Ships: Douglas Mawson
Departures: Jul 2026 to May 2027
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
$13,095
Balcony
$13,895
Suite
$22,095
From
US$14,595
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Virgin Voyages
Cruise
 (5)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departures: May 2027 to Sep 2027
Visit: Spain, France, Italy, Sicily
Inside
$1,323
Oceanview
$1,673
Balcony
$1,743
Suite
$4,200
From
US$1,323
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: France, Italy, Sicily, Spain
Inside
$851
Oceanview
$921
Balcony
$1,061
Suite
-
From
US$851
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$824
Oceanview
$924
Balcony
$1,104
Suite
-
From
US$824
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Jun 2026 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$669
Oceanview
$1,169
Balcony
$1,119
Suite
$1,349
From
US$669
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2027 to Sep 2027
Visit: Spain, France, Italy, Sicily
Inside
$1,239
Oceanview
-
Balcony
$1,629
Suite
$1,819
From
US$1,239
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Sicily, Spain, France, Italy
Inside
$821
Oceanview
$921
Balcony
$1,101
Suite
-
From
US$821
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Italy, Sicily, Spain, France
Inside
$821
Oceanview
$921
Balcony
$1,101
Suite
-
From
US$821
Per Person
View Trip
8 Day Journey to Antiquities with Viking Cruises
Cruise
 (7)

8 Days (7 Nights) Athens to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+8 more), Viking Libra, Viking Mira, Viking Neptune, Viking Saturn, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Oct 2026 to Apr 2028
Visit: Greece, Turkey, Sicily, Italy
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,499
From
US$2,599
Save 500
Per Person
View Trip
10 Day Mysteries Of History with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 24 May 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,799
Oceanview
$3,099
Balcony
$4,499
Suite
$5,799
From
US$2,799
Save 2,799
Per Person
View Trip
8 Day Mediterranean with Greece & Adriatic with Princess
Cruise
 (7)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Jun 2026 to Oct 2027
Visit: Greece, Montenegro, Sicily, Spain
Princess Standard
Princess Premier
Sanctuary Collection
Inside
$1,079
Oceanview
$1,302
Balcony
$1,604
Suite
$1,879
From
US$1,079
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Italy, Sicily, Spain, France
Inside
$836
Oceanview
$935
Balcony
$1,115
Suite
-
From
US$836
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2027
Visit: Italy, Sicily, France, Spain
Inside
$1,159
Oceanview
$1,549
Balcony
$1,599
Suite
$1,779
From
US$1,159
Per Person
View Trip
8 Day Greece And Turkiye with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 26 May 2028
Visit: Italy, Sicily, Greece, Turkey
Cunard Fare
Value Fare
Inside
$1,819
Oceanview
$1,909
Balcony
$2,359
Suite
$4,564
From
US$1,819
Per Person
View Trip
8 Day Italy, Greece And Turkey with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 May 2027
Visit: Spain, Sicily, Greece, Turkey
Bonus Onboard Credit
Value Fare
Inside
$1,139
Oceanview
$1,369
Balcony
$1,499
Suite
$3,169
From
US$1,139
Per Person
View Trip
15 Day Italy, Greece And Turkiye with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 26 May 2028
Visit: Italy, Sicily, Greece, Turkey
Cunard Fare
Value Fare
Inside
$3,384
Oceanview
$3,609
Balcony
$4,509
Suite
$8,289
From
US$3,384
Per Person
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Athens
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 31 May 2027
Visit: Spain, Sicily, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$1,201
Oceanview
$1,661
Balcony
$1,694
Suite
$2,268
From
US$1,201
Save 567
Per Person
View Trip
10 Day From Croatia to the Amalfi Coast via Sicily with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Dubrovnik to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departures: May 2027 to Oct 2027
Visit: Croatia, Italy, Greece, Sicily
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$6,798
Balcony
-
Suite
$9,431
From
US$6,798
Save 2,212
Per Person
View Trip
11 Day Italy & French Riviera Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 28 May 2027
Visit: Spain, Italy, Sicily, France
Exclusive Savings
Inside
$2,108
Oceanview
$2,535
Balcony
$2,874
Suite
$7,211
From
US$2,108
Save 1,253
Per Person
View Trip
11 Day Italy & French Riviera Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departures: May 2027 to Oct 2027
Visit: Spain, Italy, Sicily, France
Exclusive Savings
Inside
$2,120
Oceanview
$2,644
Balcony
$3,062
Suite
$7,786
From
US$2,120
Save 1,589
Per Person
View Trip
8 Day Italy & Croatia Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Bologna to Rome
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 17 May 2027
Visit: Italy, Croatia, Montenegro, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,293
Oceanview
$1,710
Balcony
$2,013
Suite
$2,478
From
US$1,293
Save 632
Per Person
View Trip
8 Day Greco-roman World with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departures: May 2027 to Aug 2027
Visit: Greece, Sicily, Malta, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,149
Suite
$4,799
From
US$3,149
Save 3,749
Per Person
View Trip
11 Day Jewels of the Mediterranean with Scenic
New ReleaseCruise

11 Days (10 Nights) Palma de Mallorca to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 May 2027
Visit: Spain, Sardinia, Sicily, Malta
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,449
Suite
$16,952
From
US$10,449
Save 3,396
Per Person
View Trip
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