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Sicily Luxury Cruises

Explore Sicily on one of 23 luxury cruises, departing from Athens, Malaga, Malta, Rome, Valletta and more. May is the most popular month to cruise to Sicily and we have over 35 departures available from five of the world's leading cruise lines specialising in luxury cruises.
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16 Days
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23 Cruises (35 Cruise Departures)
9 Day Mind and Taste Buds Awake with the Mucem in the Mediterranean with Ponant
Cruise
 (2)

9 Days (8 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 09 October 2025
Countries Visited: Italy, Sicily, Greece
INSIDE
-
OCEANVIEW
-
BALCONY
$7,620
SUITE
$12,920
From (per person) 7,620
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Valletta to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: May 2026 to Jul 2026
Countries Visited: Malta, Sicily, Italy
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$7,138
BALCONY
-
SUITE
$9,761
Save (per person) 10,281
From (per person) 7,138
View Trip
9 Day A Celebration of Art Featuring the 61st Venice Biennale with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 01 July 2026
Countries Visited: Malta, Sicily, Italy
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$8,450
SUITE
$15,500
From (per person) 8,450
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 11 July 2026
Countries Visited: Italy, Sicily, Malta
2 for 1 Fare + Fly Free Economy2 for 1 Fares
INSIDE
-
OCEANVIEW
$7,138
BALCONY
-
SUITE
$9,761
Save (per person) 7,352
From (per person) 7,138
View Trip
8 Day Iberian Peninsula & Sicily with Ponant
Cruise
 (1)

8 Days (7 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 28 April 2026
Countries Visited: Spain, Sicily, Malta
INSIDE
-
OCEANVIEW
-
BALCONY
$5,250
SUITE
$9,730
From (per person) 5,250
View Trip
11 Day Mediterranean Delights with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Valletta to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 20 July 2026
Countries Visited: Malta, Sicily, Tunisia
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$7,728
BALCONY
-
SUITE
$10,649
Save (per person) 7,962
From (per person) 7,728
View Trip
11 Day Italy Intensive Cruise: Venice, Sicily & Amalfi with Azamara Cruises
Cruise
 (1)

11 Days (10 Nights) Venice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 05 May 2027
Countries Visited: Italy, Montenegro, Sicily
INSIDE
$2,759
OCEANVIEW
$3,179
BALCONY
$4,139
SUITE
$5,979
From (per person) 2,759
View Trip
9 Day A Circumnavigation of Sicily - with Smithsonian Journeys with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Aug 2025 to Aug 2026
Countries Visited: Malta, Sicily, Tunisia
INSIDE
-
OCEANVIEW
-
BALCONY
$8,370
SUITE
$14,040
From (per person) 8,370
View Trip
9 Day Epicurean Delights: The Food & Wine of Sicily with Ponant
Cruise

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 11 April 2026
Countries Visited: Malta, Sicily, Italy
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$9,260
SUITE
$17,100
From (per person) 9,260
View Trip
6 Day Italian Escape with Ponant
Cruise
 (2)

6 Days (5 Nights) Valletta to Amalfi
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 17 November 2025
Countries Visited: Malta, Sicily, Italy
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$3,450
SUITE
$6,400
From (per person) 3,450
View Trip
11 Day Mediterranean Crossroads with Emerald Cruises
New ReleaseCruise
 (3)

11 Days (10 Nights) Athens to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 09 November 2025
Countries Visited: Greece, Sicily, Malta
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,294
Save (per person) 11,596
From (per person) 11,294
View Trip
8 Day Mediterranean Cruise: Italy & Greece with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 December 2026
Countries Visited: Italy, Sicily, Greece
INSIDE
$1,699
OCEANVIEW
$1,959
BALCONY
$2,519
SUITE
$3,959
From (per person) 1,699
View Trip
12 Day Italy Intensive Cruise: Bologna, Sicily & Amalfi with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Venice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 May 2027
Countries Visited: Italy, Montenegro, Sicily
INSIDE
$3,279
OCEANVIEW
$3,779
BALCONY
$4,739
SUITE
$6,819
From (per person) 3,279
View Trip
11 Day Ancient Civilisations, from Italy to Greece with Ponant
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Champlain
Departure: 01 October 2026
Countries Visited: Italy, Sicily, Greece
INSIDE
-
OCEANVIEW
-
BALCONY
$8,470
SUITE
$15,780
From (per person) 8,470
View Trip
10 Day Authentic Mediterranean shores with Ponant
Cruise
 (1)

10 Days (9 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 October 2026
Countries Visited: Malta, Sicily, Italy
INSIDE
-
OCEANVIEW
$6,950
BALCONY
$7,320
SUITE
$13,630
From (per person) 6,950
View Trip
12 Day Italy Cruise: Venice, Sicily & Rome with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 August 2026
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$4,109
OCEANVIEW
$4,539
BALCONY
$5,459
SUITE
$7,389
From (per person) 4,109
View Trip
12 Day Sicily, the Amalfi Coast & Rome with Tauck
Cruise

12 Days (11 Nights) Malta to Rome
Operated By: Tauck
Departures: Oct 2025 to Oct 2026
Countries Visited: Malta, Sicily, Italy
Complimentary Hotel Night
From (per person) 12,490
View Trip
8 Day Italian Treasures: Amalfi Coast, Sicily and Malta with Scenic
New ReleaseCruise

8 Days (7 Nights) Rome to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 07 June 2026
Countries Visited: Italy, Sicily, Malta
2 for 1 Fares + Fly Free Premium Economy2 for 1 Fares + Fly Free Business Class
INSIDE
-
OCEANVIEW
-
BALCONY
$11,240
SUITE
$25,940
Save (per person) 11,250
From (per person) 11,240
View Trip
12 Day Rome, the Amalfi Coast & Sicily with Tauck
Cruise

12 Days (11 Nights) Rome to Malta
Operated By: Tauck
Departures: Oct 2025 to Oct 2026
Countries Visited: Italy, Sicily, Malta
Complimentary Hotel Night
From (per person) 12,490
View Trip
8 Day Island Odyssey: Malta, Sicily & the Greek Isles with Scenic
New ReleaseCruise

8 Days (7 Nights) Valletta to Athens
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 June 2026
Countries Visited: Malta, Sicily, Greece
2 for 1 Fares + Fly Free Premium Economy2 for 1 Fares + Fly Free Business Class
INSIDE
-
OCEANVIEW
-
BALCONY
$11,625
SUITE
$14,705
Save (per person) 11,705
From (per person) 11,625
View Trip
11 Day 5th Opera Festival at Sea with Ponant
Cruise

11 Days (10 Nights) Venice to Nice
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 22 June 2026
Countries Visited: Italy, Sicily, France
INSIDE
-
OCEANVIEW
-
BALCONY
$12,950
SUITE
$22,030
From (per person) 12,950
View Trip
16 Day Italian Treasures with Malta - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

16 Days Venice to Valletta
Operated By: Scenic
Ship: Scenic Eclipse II
Departure: 30 May 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Italy, Sicily, Malta
2 for 1 Fares + Fly Free Premium Economy2 for 1 Cruise Fares
INSIDE
-
OCEANVIEW
-
BALCONY
$22,360
SUITE
$37,060
Save (per person) 11,250
From (per person) 22,360
View Trip
9 Day Cruising Southern Italy and Sicily - with Smithsonian Journeys with Ponant
Cruise

9 Days (8 Nights) Valletta to Livorno
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departures: Aug 2025 to Sep 2026
Countries Visited: Malta, Sicily, Italy
Exclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$8,220
SUITE
$13,750
From (per person) 8,220
View Trip
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10 Day

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Palermo

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