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Sicily Luxury Cruises

Explore Sicily on one of 184 luxury cruises, departing from Antalya, Athens, Barcelona, Dubrovnik, Florence and more. May, June and October are the most popular months to cruise to Sicily and we have over 220 departures available from twelve of the world's leading cruise lines specialising in luxury cruises.
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6 Days
22 Days
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184 Cruises (220 Cruise Departures)
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Valletta to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 05 May 2026
Visit: Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$24,425
From
US$24,425
Save 725
Per Person
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Tour + Cruise

12 Days Malta to Rome
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Apr 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$12,490
Suite
$16,490
From
US$12,490
Per Person
View Trip
8 Day Under Sail from the Riviera to Sicily with Ponant
Cruise

8 Days (7 Nights) Nice to Palermo
Cruise Line: Ponant
Ship: Le Ponant
Departure: 01 June 2027
Visit: France, Italy, Sicily
Inside
-
Oceanview
$11,380
Balcony
$18,350
Suite
$20,450
From
US$11,380
Per Person
View Trip
9 Day Historical Cities of the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 01 June 2026
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$7,540
Suite
$14,120
From
US$7,540
Per Person
View Trip
8 Day Stars Of The Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 04 July 2027
Visit: Greece, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,913
Suite
$10,648
From
US$9,913
Save 10,285
Per Person
View Trip
8 Day Majestic Medieval Fortresses with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 15 October 2027
Visit: Italy, Croatia, Greece, Sicily
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$1,899
Oceanview
$2,049
Balcony
$3,226
Suite
$4,778
From
US$1,899
Save 1,899
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy
Bonus Onboard Credit
Inside
$1,359
Oceanview
$1,499
Balcony
$1,989
Suite
-
From
US$1,359
Per Person
View Trip
8 Day Ionian Exploration with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 October 2027
Visit: Greece, Turkey, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$4,491
From
US$2,599
Save 2,599
Per Person
View Trip
11 Day Monte Carlo to Rome with Silversea
Cruise

11 Days (10 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 08 October 2026
Visit: Monaco, France, Corsica, Italy, Sicily
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,380
Suite
$24,920
From
US$9,380
Save 4,020
Per Person
View Trip
11 Day Italy Intensive Cruise: Florence, Rome & Amalfi with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 May 2026
Visit: France, Italy, Sicily, Montenegro
Azamara Always Included
Inside
$1,719
Oceanview
$2,029
Balcony
-
Suite
$4,426
From
US$1,719
Per Person
View Trip
15 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 21 September 2026
Visit: Italy, Sicily, Greece, Turkey
Bonus Onboard Credit
Inside
$2,979
Oceanview
$3,259
Balcony
$3,859
Suite
$6,540
From
US$2,979
Per Person
View Trip
9 Day Ancient Cities of the Mediterranean with Ponant
Cruise

9 Days (8 Nights) Athens to Valletta
Cruise Line: Ponant
Ships: Le Champlain, Le Dumont d’Urville
Departures: Nov 2026 to Oct 2027
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$7,110
Suite
$12,620
From
US$7,110
Per Person
View Trip
8 Day Italy, Greece And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 27 August 2027
Visit: Italy, Croatia, Greece, Sicily
Bonus Onboard Credit
Inside
$1,109
Oceanview
$1,199
Balcony
$1,339
Suite
$2,469
From
US$1,109
Per Person
View Trip
13 Day Minarets & Mosaics with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Athens to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 05 July 2026
Visit: Greece, Turkey, Tunisia, Sicily, Monaco
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,400
Oceanview
$2,640
Balcony
$3,875
Suite
$5,272
From
US$2,400
Save 5,598
Per Person
View Trip
8 Day Spain, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 04 June 2027
Visit: Italy, Croatia, Sicily, Spain
Bonus Onboard Credit
Inside
$1,309
Oceanview
$1,429
Balcony
$1,599
Suite
$3,499
From
US$1,309
Per Person
View Trip
11 Day Jewels of the Mediterranean with Scenic
New ReleaseCruise

11 Days (10 Nights) Palma de Mallorca to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 May 2027
Visit: Spain, Sardinia, Sicily, Malta
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,240
Suite
$18,918
From
US$12,240
Save 1,605
Per Person
View Trip
10 Day From Croatia to the Amalfi Coast via Sicily with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Dubrovnik to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departures: May 2027 to Oct 2027
Visit: Croatia, Italy, Greece, Sicily
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
$7,596
Balcony
-
Suite
$10,150
From
US$7,596
Save 952
Per Person
View Trip
11 Day Venice to Rome with Silversea
Cruise
 (1)

11 Days (10 Nights) Venice to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 13 November 2026
Visit: Italy, Montenegro, Malta, Sicily
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,660
Suite
$12,480
From
US$6,660
Save 4,440
Per Person
View Trip
9 Day Ancient Jewels of the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Athens to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 23 June 2026
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$7,920
Suite
$14,870
From
US$7,920
Per Person
View Trip
11 Day Rome to Venice with Silversea
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 September 2026
Visit: Italy, Sicily, Montenegro, Croatia
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$11,200
Suite
$20,200
From
US$11,200
Per Person
View Trip
8 Day A Journey To Italian Hidden Gems & The Heartbeat Of Catalan Culture with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 May 2026
Visit: Italy, Sicily, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,520
From
US$5,520
Per Person
View Trip
8 Day Greco-roman World with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departures: May 2027 to Aug 2027
Visit: Greece, Sicily, Malta, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,028
Suite
$4,871
From
US$3,028
Save 3,324
Per Person
View Trip
8 Day Italy And Adriatic with Cunard
Cruise
 (1)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 06 July 2026
Visit: Italy, Croatia, Malta, Sicily
Inside
$1,229
Oceanview
$1,279
Balcony
$1,659
Suite
$2,969
From
US$1,229
Per Person
View Trip
12 Day Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Athens to Malaga
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 28 June 2026
Visit: Greece, Sicily, Sardinia, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$38,828
From
US$38,828
Save 1,162
Per Person
View Trip
8 Day Viva Italia with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 23 April 2027
Visit: Italy, Sicily, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,077
Suite
$4,726
From
US$3,077
Save 3,221
Per Person
View Trip
8 Day Greece And Italy with Cunard
Cruise
 (13)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 21 May 2027
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Inside
$1,389
Oceanview
$1,429
Balcony
$2,029
Suite
$3,499
From
US$1,389
Per Person
View Trip
8 Day A Journey Through Italy's Timeless Wonders to Istanbul's Vibrant Soul with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 04 December 2027
Visit: Italy, Sicily, Greece, Turkey
Inside
-
Oceanview
-
Balcony
-
Suite
$4,420
From
US$4,420
Per Person
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 September 2026
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Inside
$1,589
Oceanview
$1,669
Balcony
$1,919
Suite
-
From
US$1,589
Per Person
View Trip
8 Day Greece And Turkey with Cunard
Cruise
 (13)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Inside
$1,319
Oceanview
$1,429
Balcony
$1,549
Suite
$3,229
From
US$1,319
Per Person
View Trip
11 Day Visions Of Byzantium with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 17 August 2026
Visit: Spain, Sicily, Greece, Turkey
Your World Inclusions
Exclusive Savings
Inside
$2,400
Oceanview
$2,607
Balcony
$4,099
Suite
$4,935
From
US$2,400
Save 3,998
Per Person
View Trip
Results: 31-60 of 184

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