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Sicily Luxury Cruises

Explore Sicily on one of 171 luxury cruises, departing from Antalya, Athens, Barcelona, Dubrovnik, Florence and more. May, June and October are the most popular months to cruise to Sicily and we have over 198 departures available from eleven of the world's leading cruise lines specialising in luxury cruises.
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22 Days
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171 Cruises (198 Cruise Departures)
15 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 21 September 2026
Visit: Italy, Sicily, Greece, Turkey
Inside
$2,969
Oceanview
$3,249
Balcony
$3,839
Suite
$6,965
From
US$2,969
Per Person
View Trip
13 Day Minarets & Mosaics with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Athens to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 05 July 2026
Visit: Greece, Turkey, Tunisia, Sicily, Monaco
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,800
Oceanview
$3,022
Balcony
$4,516
Suite
$6,145
From
US$2,800
Save 5,198
Per Person
View Trip
8 Day Greece, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia
Inside
$1,409
Oceanview
$1,609
Balcony
$1,909
Suite
$4,059
From
US$1,409
Per Person
View Trip
9 Day Ancient Jewels of the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Athens to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 23 June 2026
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$7,920
Suite
$14,870
From
US$7,920
Per Person
View Trip
10 Day Civitavecchia (Rome) to Athens (Piraeus) with Silversea
Cruise
 (1)

10 Days (9 Nights) Rome to Athens
Cruise Line: Silversea
Ship: Silver Nova
Departure: 16 April 2027
Visit: Italy, Sicily, Malta, Greece
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,400
Suite
$9,180
From
US$6,400
Save 1,600
Per Person
View Trip
10 Day A Journey Through The Artistic And Historic Spirit Of Mediterranean Coastal Beauty with Explora Journeys
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 12 October 2026
Visit: Spain, France, Italy, Sicily
A Suite Invitation
Sky & Sea
Inside
-
Oceanview
-
Balcony
$6,840
Suite
$7,735
From
US$6,840
Per Person
View Trip
8 Day Majestic Medieval Fortresses with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 15 October 2027
Visit: Italy, Croatia, Greece, Sicily
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$1,899
Oceanview
$2,049
Balcony
$3,226
Suite
$4,778
From
US$1,899
Save 1,899
Per Person
View Trip
10 Day Exploring Ancient Empires with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Departure: 29 March 2027
Visit: Italy, Sicily, Greece, Turkey
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,399
Oceanview
$2,594
Balcony
$4,098
Suite
$5,941
From
US$2,399
Save 2,399
Per Person
View Trip
11 Day Italy Intensive Cruise: Florence, Rome & Amalfi with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 May 2026
Visit: France, Italy, Sicily, Montenegro
Azamara Always Included
Exclusive Savings
Inside
$3,049
Oceanview
$3,602
Balcony
$4,863
Suite
$8,170
From
US$3,049
Save 70
Per Person
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 September 2026
Visit: Turkey, Greece, Sicily, Italy
Inside
$1,529
Oceanview
$1,659
Balcony
$1,919
Suite
-
From
US$1,529
Per Person
View Trip
8 Day Greece And Italy with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey
Inside
$1,319
Oceanview
$1,429
Balcony
$1,569
Suite
$3,279
From
US$1,319
Per Person
View Trip
11 Day Iconic Greek Isles with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Departure: 09 July 2027
Visit: Turkey, Greece, Sicily, Italy
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$3,230
Oceanview
$3,473
Balcony
$5,267
Suite
$7,304
From
US$3,230
Save 3,368
Per Person
View Trip
8 Day Spotlight On Sparkling Wines with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 October 2026
Visit: Italy, Sicily, Malta, Croatia
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,709
Suite
$7,954
From
US$7,709
Save 12,389
Per Person
View Trip
11 Day Rome to Venice with Silversea
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 September 2026
Visit: Italy, Sicily, Montenegro, Croatia
All-Inclusive Fare
Inside
-
Oceanview
$10,500
Balcony
$11,800
Suite
-
From
US$10,500
Per Person
View Trip
11 Day Visions Of Byzantium with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Istanbul
Cruise Line: Oceania Cruises
Departure: 17 August 2026
Visit: Spain, Sicily, Greece, Turkey
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,663
Oceanview
$2,951
Balcony
$4,395
Suite
$6,044
From
US$2,663
Save 3,735
Per Person
View Trip
8 Day Greco-roman World with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departures: May 2027 to Aug 2027
Visit: Greece, Sicily, Malta, Italy
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,737
Suite
$4,677
From
US$2,737
Save 3,118
Per Person
View Trip
8 Day Ionian Exploration with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 October 2027
Visit: Greece, Turkey, Sicily, Italy
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,181
Suite
$4,491
From
US$3,181
Save 3,317
Per Person
View Trip
8 Day Greece, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 17 September 2027
Visit: Italy, Croatia, Greece, Sicily
Inside
$1,059
Oceanview
$1,159
Balcony
$1,309
Suite
$3,089
From
US$1,059
Per Person
View Trip
8 Day Italy, Greece And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Jun 2027 to Jul 2027
Visit: Italy, Croatia, Greece, Sicily
Inside
$1,059
Oceanview
$1,159
Balcony
$1,309
Suite
$2,849
From
US$1,059
Per Person
View Trip
8 Day Italy And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Visit: Spain, Sardinia, Sicily, Italy
Inside
$1,369
Oceanview
$1,439
Balcony
$1,549
Suite
$3,079
From
US$1,369
Per Person
View Trip
11 Day Jewels of the Mediterranean with Scenic
New ReleaseCruise

11 Days (10 Nights) Palma de Mallorca to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 May 2027
Visit: Spain, Sardinia, Sicily, Malta
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,731
Suite
$17,637
From
US$9,731
Save 17,259
Per Person
View Trip
17 Day Discover the Adriatic from Venice to Rome with Emerald Cruises
New ReleaseCruise

17 Days (16 Nights) Venice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 04 September 2027
Visit: Italy, Croatia, Greece, Sicily
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
$16,738
Balcony
-
Suite
$21,782
From
US$16,738
Save 17,742
Per Person
View Trip
10 Day Mysteries Of History with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Departure: 24 May 2027
Visit: Italy, Sicily, Greece, Turkey
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,643
Oceanview
$2,885
Balcony
$4,389
Suite
$6,232
From
US$2,643
Save 2,755
Per Person
View Trip
8 Day Greece, Italy And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 22 October 2027
Visit: Italy, Greece, Sicily, Spain
Inside
$1,399
Oceanview
$1,599
Balcony
$1,899
Suite
$4,049
From
US$1,399
Per Person
View Trip
8 Day Spain, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 04 June 2027
Visit: Italy, Croatia, Sicily, Spain
Inside
$1,309
Oceanview
$1,429
Balcony
$1,629
Suite
$3,549
From
US$1,309
Per Person
View Trip
8 Day Greece And Italy with Cunard
Cruise
 (13)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 21 May 2027
Visit: Turkey, Greece, Sicily, Italy
Inside
$1,319
Oceanview
$1,429
Balcony
$1,629
Suite
$3,279
From
US$1,319
Per Person
View Trip
8 Day Croatian Culture & Cuisine with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 09 September 2027
Visit: Italy, Sicily, Montenegro, Croatia
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,679
Suite
$7,267
From
US$6,679
Save 11,919
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 May 2026
Visit: Spain, Corsica, Sicily, Italy
Inside
$1,179
Oceanview
$1,399
Balcony
$1,649
Suite
-
From
US$1,179
Per Person
View Trip
10 Day Italy & Greece Cruise: Amalfi, Crete & Santorini with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 August 2027
Visit: Italy, Sicily, Greece, Turkey
Azamara Always Included
Exclusive Savings
Inside
$2,875
Oceanview
$3,243
Balcony
$3,951
Suite
$5,736
From
US$2,875
Save 64
Per Person
View Trip
11 Day Havens Of Italy & Spain with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Monte Carlo to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 October 2026
Visit: Monaco, Italy, Sardinia, Sicily, Spain
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,400
Oceanview
$2,584
Balcony
$3,981
Suite
$5,533
From
US$2,400
Save 3,598
Per Person
View Trip
Results: 31-60 of 171

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