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Sicily Luxury Cruises

Explore Sicily on one of 192 luxury cruises, departing from Antalya, Athens, Barcelona, Bologna, Dubrovnik and more. October is the most popular month to cruise to Sicily and we have over 222 departures available from twelve of the world's leading cruise lines specialising in luxury cruises.
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192 Cruises (222 Cruise Departures)
12 Day Italy Intensive Cruise: Florence, Sorrento & Sicily with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 September 2027
Visit: France, Italy, Sicily, Montenegro
Azamara Always Included
Inside
$5,119
Oceanview
$5,719
Balcony
$6,879
Suite
$9,869
From
US$5,119
Per Person
View Trip
9 Day Legendary Shores of Italy and Croatia with Ponant
Cruise
 (2)

9 Days (8 Nights) Venice to Rome
Cruise Line: Ponant
Ship: Le Boreal
Departure: 20 May 2027
Visit: Italy, Croatia, Sicily
Inside
-
Oceanview
$6,300
Balcony
$6,630
Suite
$12,350
From
US$6,300
Per Person
View Trip
10 Day Alluring Ancient Ruins with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 15 May 2027
Visit: Turkey, Greece, Sicily, Italy, Sardinia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,799
Oceanview
$2,949
Balcony
$4,499
Suite
$6,399
From
US$2,799
Save 2,799
Per Person
View Trip
15 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia, Spain
Value Fare
Inside
$2,629
Oceanview
$2,929
Balcony
$3,679
Suite
$7,979
From
US$2,629
Per Person
View Trip
9 Day Greece, Italy & Spain Cruise: Athens, Siracusa & Malaga with Azamara Cruises
Cruise
 (5)

9 Days (8 Nights) Athens to Malaga
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 26 November 2026
Visit: Greece, Sicily, Malta, Tunisia, Spain
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$1,509
Oceanview
$1,729
Balcony
$2,149
Suite
$3,379
From
US$1,509
Per Person
View Trip
8 Day Italy, Algeria & Spain Cruise: Trapani, Algiers & Granada with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Malaga
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 02 December 2027
Visit: Italy, Sicily, Tunisia, Algeria, Spain
Azamara Always Included
Inside
$1,739
Oceanview
$1,959
Balcony
$2,619
Suite
$3,749
From
US$1,739
Per Person
View Trip
15 Day Mediterranean, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Bonus Onboard Credit
Value Fare
Inside
$2,399
Oceanview
$2,699
Balcony
$2,859
Suite
$6,119
From
US$2,399
Per Person
View Trip
9 Day Ancient Jewels of the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Athens to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 23 June 2026
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$8,740
Suite
$14,870
From
US$8,740
Per Person
View Trip
8 Day Italy, Greece And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 07 July 2028
Visit: Italy, Croatia, Greece, Sicily
Cunard Fare
Value Fare
Inside
$1,649
Oceanview
$1,784
Balcony
$2,144
Suite
$4,169
From
US$1,649
Per Person
View Trip
9 Day From Malta to the Shores of the Adriatic with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 19 August 2027
Visit: Malta, Sicily, Italy, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$6,510
Suite
$12,090
From
US$6,510
Per Person
View Trip
15 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Istanbul to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy, Croatia
Value Fare
Inside
$2,869
Oceanview
$3,219
Balcony
$3,919
Suite
$8,569
From
US$2,869
Per Person
View Trip
10 Day Exploring Ancient Empires with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 29 March 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Inclusions
Exclusive Savings
Inside
$2,160
Oceanview
$2,385
Balcony
$3,780
Suite
$5,490
From
US$2,160
Save 2,638
Per Person
View Trip
11 Day Made in Italy, the Luxury Edition with Ponant
Cruise
 (2)

11 Days (10 Nights) Florence to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 08 September 2027
Visit: Italy, Sicily
Inside
-
Oceanview
$16,120
Balcony
$17,010
Suite
$32,020
From
US$16,120
Per Person
View Trip
12 Day Italy Intensive Cruise: Bologna, Sicily & Amalfi with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Venice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 May 2027
Visit: Italy, Montenegro, Sicily
Azamara Always Included
Inside
$3,939
Oceanview
$4,529
Balcony
$6,209
Suite
$8,579
From
US$3,939
Per Person
View Trip
9 Day Tribute to Maria Callas with Ponant
Cruise
 (2)

9 Days (8 Nights) Athens to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 29 September 2027
Visit: Greece, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$9,230
Suite
$17,350
From
US$9,230
Per Person
View Trip
10 Day Civitavecchia (Rome) to Athens (Piraeus) with Silversea
Cruise
 (1)

10 Days (9 Nights) Rome to Athens
Cruise Line: Silversea
Ship: Silver Nova
Departure: 16 April 2027
Visit: Italy, Sicily, Malta, Greece
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,300
Suite
$11,200
From
US$7,300
Save 1,500
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 May 2026
Visit: Spain, Corsica, Sicily, Italy
Inside
$919
Oceanview
$919
Balcony
$1,129
Suite
$3,079
From
US$919
Per Person
View Trip
15 Day Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 August 2026
Visit: Italy, Spain, France, Sardinia, Sicily
Inside
$2,859
Oceanview
$3,159
Balcony
$3,669
Suite
$6,839
From
US$2,859
Per Person
View Trip
12 Day A Journey From Ligurian Shores To The Cyclades' Dazzling Beauty with Explora Journeys
Cruise
 (1)

12 Days (11 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 March 2027
Visit: Spain, Italy, Sicily, Malta, Greece
Inside
-
Oceanview
-
Balcony
-
Suite
$6,015
From
US$6,015
Per Person
View Trip
15 Day Adriatic And Malta with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 30 July 2027
Visit: Italy, Malta, Croatia, Greece, Sicily
Cunard Fare
Value Fare
Inside
$2,929
Oceanview
$3,279
Balcony
$3,729
Suite
$8,199
From
US$2,929
Per Person
View Trip
11 Day Enchanting Greece & the Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

11 Days (10 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 17 October 2026
Visit: Greece, Sicily, Malta, Italy
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$25,145
From
US$25,145
Save 1,800
Per Person
View Trip
15 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 06 July 2026
Visit: Italy, Croatia, Malta, Sicily, France
Cunard Fare
Inside
$2,319
Oceanview
$2,379
Balcony
$2,829
Suite
$5,359
From
US$2,319
Per Person
View Trip
11 Day A Journey Through The Mediterranean’s Historic Crossroads with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 04 January 2027
Visit: Italy, Sicily, Malta, Tunisia
Inside
-
Oceanview
-
Balcony
-
Suite
$5,390
From
US$5,390
Per Person
View Trip
15 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 21 September 2026
Visit: Italy, Sicily, Greece, Turkey
Bonus Onboard Credit
Value Fare
Cunard Fare
Inside
$2,739
Oceanview
$2,909
Balcony
$3,569
Suite
$8,979
From
US$2,739
Per Person
View Trip
11 Day Mediterranean & Egypt Cruise: Alexandria, Heraklion & Rome with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 December 2026
Visit: Greece, Egypt, Malta, Sicily, Italy
Azamara Always Included
Inside
$1,919
Oceanview
$2,219
Balcony
$2,539
Suite
$3,989
From
US$1,919
Per Person
View Trip
11 Day Fusina (Venice) to Civitavecchia (Rome) with Silversea
Cruise
 (1)

11 Days (10 Nights) Venice to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 28 October 2027
Visit: Italy, Montenegro, Croatia, Sicily
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,300
Suite
$11,900
From
US$7,300
Save 1,500
Per Person
View Trip
11 Day Mediterranean Medley with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 02 July 2026
Visit: Italy, Sicily, Malta, Spain, France, Monaco
Your World Inclusions
Exclusive Savings
Inside
$2,700
Oceanview
$3,150
Balcony
$4,575
Suite
$11,699
From
US$2,700
Save 4,498
Per Person
View Trip
8 Day A Journey Through Istanbul's Cosmopolitan Vibrancy to Rome's Timeless Wonders with Explora Journeys
Cruise

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 12 December 2027
Visit: Turkey, Greece, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$4,420
From
US$4,420
Per Person
View Trip
12 Day Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Athens to Malaga
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 28 June 2026
Visit: Greece, Sicily, Sardinia, Spain
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$36,117
From
US$36,117
Save 3,873
Per Person
View Trip
9 Day Croatia, Malta & Italy with Seabourn
Cruise

9 Days (8 Nights) Venice to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 13 June 2027
Visit: Italy, Croatia, Malta, Sicily
Inside
-
Oceanview
-
Balcony
$8,329
Suite
$12,749
From
US$8,329
Per Person
View Trip
Results: 61-90 of 192

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