Home > Cruises > Europe Cruises > Mediterranean Cruises > Sicily Cruises > Sicily Luxury Cruises

Sicily Luxury Cruises

Explore Sicily on one of 184 luxury cruises, departing from Antalya, Athens, Barcelona, Dubrovnik, Florence and more. May, June and October are the most popular months to cruise to Sicily and we have over 220 departures available from twelve of the world's leading cruise lines specialising in luxury cruises.
Filter Results
Departures
Show More...
Duration
6 Days
22 Days
Countries Visited
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$1,100pp
$39,990pp
Countries
Show More...
Filter Results
184 Cruises (220 Cruise Departures)
11 Day Visions Of Byzantium with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 17 August 2026
Visit: Spain, Sicily, Greece, Turkey
Your World Inclusions
Exclusive Savings
Inside
$2,400
Oceanview
$2,607
Balcony
$4,099
Suite
$4,935
From
US$2,400
Save 3,998
Per Person
View Trip
8 Day Greece And Italy with Cunard
Cruise
 (13)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 21 May 2027
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Inside
$1,389
Oceanview
$1,429
Balcony
$2,029
Suite
$3,499
From
US$1,389
Per Person
View Trip
11 Day Havens Of Italy & Spain with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Monte Carlo to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 October 2026
Visit: Monaco, Italy, Sardinia, Sicily, Spain
Your World Inclusions
Exclusive Savings
Inside
$2,362
Oceanview
$2,570
Balcony
$3,734
Suite
$5,189
From
US$2,362
Save 3,936
Per Person
View Trip
10 Day Exploring Ancient Empires with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 29 March 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,399
Oceanview
$2,594
Balcony
$4,098
Suite
$5,941
From
US$2,399
Save 2,399
Per Person
View Trip
10 Day From the Iberian Shores to the Italian Coast with Ponant
Cruise

10 Days (9 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 04 April 2027
Visit: Spain, Sicily, Italy, Malta
Inside
-
Oceanview
-
Balcony
$6,880
Suite
$12,750
From
US$6,880
Per Person
View Trip
8 Day Greece And Turkey with Cunard
Cruise
 (13)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Inside
$1,319
Oceanview
$1,429
Balcony
$1,549
Suite
$3,229
From
US$1,319
Per Person
View Trip
9 Day Ancient Jewels of the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Athens to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 23 June 2026
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$7,920
Suite
$14,870
From
US$7,920
Per Person
View Trip
8 Day Italy And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Visit: Spain, Sardinia, Sicily, Italy
Bonus Onboard Credit
Inside
$1,519
Oceanview
$1,449
Balcony
$2,059
Suite
$2,889
From
US$1,449
Per Person
View Trip
15 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 21 September 2026
Visit: Italy, Sicily, Greece, Turkey
Bonus Onboard Credit
Inside
$2,979
Oceanview
$3,259
Balcony
$3,859
Suite
$6,540
From
US$2,979
Per Person
View Trip
8 Day Italy, Greece And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 06 August 2027
Visit: Italy, Croatia, Greece, Sicily
Bonus Onboard Credit
Inside
$1,269
Oceanview
$1,359
Balcony
$1,429
Suite
$2,459
From
US$1,269
Per Person
View Trip
10 Day Mysteries Of History with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 24 May 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,643
Oceanview
$2,885
Balcony
$4,389
Suite
$6,232
From
US$2,643
Save 2,755
Per Person
View Trip
11 Day Fusina (Venice) to Civitavecchia (Rome) with Silversea
Cruise
 (1)

11 Days (10 Nights) Venice to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 28 October 2027
Visit: Italy, Montenegro, Croatia, Sicily
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,280
Suite
$11,340
From
US$7,280
Save 1,820
Per Person
View Trip
13 Day Minarets & Mosaics with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Athens to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 05 July 2026
Visit: Greece, Turkey, Tunisia, Sicily, Monaco
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,400
Oceanview
$2,640
Balcony
$3,875
Suite
$5,272
From
US$2,400
Save 5,598
Per Person
View Trip
10 Day Italy & Greece Cruise: Amalfi, Crete & Santorini with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 August 2027
Visit: Italy, Sicily, Greece, Turkey
Azamara Always Included
Exclusive Savings
Inside
$4,048
Oceanview
$4,582
Balcony
$5,600
Suite
$8,171
From
US$4,048
Save 101
Per Person
View Trip
8 Day Greece, Italy And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 22 October 2027
Visit: Italy, Greece, Sicily, Spain
Inside
$1,399
Oceanview
$1,599
Balcony
$1,899
Suite
$4,049
From
US$1,399
Per Person
View Trip
8 Day Greece, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 17 September 2027
Visit: Italy, Croatia, Greece, Sicily
Bonus Onboard Credit
Inside
$1,249
Oceanview
$1,339
Balcony
$1,439
Suite
$3,039
From
US$1,249
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 May 2026
Visit: Spain, Corsica, Sicily, Italy
Inside
$1,429
Oceanview
$1,619
Balcony
$1,779
Suite
$3,009
From
US$1,429
Per Person
View Trip
8 Day Viva Italia with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 23 April 2027
Visit: Italy, Sicily, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,077
Suite
$4,726
From
US$3,077
Save 3,221
Per Person
View Trip
8 Day Italy, Greece And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Jun 2027 to Jul 2027
Visit: Italy, Croatia, Greece, Sicily
Bonus Onboard Credit
Inside
$1,239
Oceanview
$1,299
Balcony
$1,439
Suite
$2,569
From
US$1,239
Per Person
View Trip
11 Day Venice to Rome with Silversea
Cruise
 (1)

11 Days (10 Nights) Venice to Rome
Cruise Line: Silversea
Ship: Silver Nova
Departure: 13 November 2026
Visit: Italy, Montenegro, Malta, Sicily
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,660
Suite
$12,480
From
US$6,660
Save 4,440
Per Person
View Trip
10 Day Trojan Trek Revisited with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 July 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,837
Oceanview
$3,080
Balcony
$4,680
Suite
$6,523
From
US$2,837
Save 2,961
Per Person
View Trip
11 Day Rome to Venice with Silversea
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 September 2026
Visit: Italy, Sicily, Montenegro, Croatia
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$11,200
Suite
$20,200
From
US$11,200
Per Person
View Trip
8 Day Spotlight On Sparkling Wines with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 October 2026
Visit: Italy, Sicily, Malta, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,462
Suite
$12,903
From
US$12,462
Save 12,936
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy
Bonus Onboard Credit
Inside
$1,359
Oceanview
$1,499
Balcony
$1,989
Suite
-
From
US$1,359
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: Mar 2026 to Aug 2026
Visit: France, Italy, Malta, Sicily
All-Inclusive Plus Fare
All-Inclusive Fare
Last Minute Fare
Exclusive Savings
Inside
-
Oceanview
$6,950
Balcony
$7,450
Suite
$14,040
From
US$6,950
Save 6,240
Per Person
View Trip
11 Day Jewels of the Mediterranean with Scenic
New ReleaseCruise

11 Days (10 Nights) Palma de Mallorca to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 May 2027
Visit: Spain, Sardinia, Sicily, Malta
Select Fare
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,240
Suite
$18,918
From
US$12,240
Save 1,605
Per Person
View Trip
8 Day History & Heritage with Regent Seven Seas
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 05 August 2027
Visit: Greece, Turkey, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,934
Suite
$9,277
From
US$8,934
Save 9,264
Per Person
View Trip
8 Day Ionian Exploration with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 October 2027
Visit: Greece, Turkey, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$4,491
From
US$2,599
Save 2,599
Per Person
View Trip
8 Day Fusina (Venice) to Monte Carlo with Silversea
Cruise

8 Days (7 Nights) Venice to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 August 2027
Visit: Italy, Croatia, Sicily, Malta, Monaco
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,900
Suite
$7,890
From
US$4,900
Save 2,100
Per Person
View Trip
9 Day Croatia, Malta & Italy with Seabourn
Cruise

9 Days (8 Nights) Venice to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 13 June 2027
Visit: Italy, Croatia, Malta, Sicily
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,151
Suite
$12,071
From
US$8,151
Save 148
Per Person
View Trip
Results: 61-90 of 184

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Cruises Luxury Cruises Short Break Cruises

Trip Lengths

10 Day 2 Week 3 Week 7 Day

Departure Months

March April May June July August September October November December January February

Cities

Palermo

Cruise Lines Exploring The Med

APT Med Cruises Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations