Home > Cruises > Europe Cruises > Mediterranean Cruises > Sicily Cruises > Sicily Luxury Cruises

Sicily Luxury Cruises

Explore Sicily on one of 207 luxury cruises, departing from Antalya, Athens, Barcelona, Bologna, Dubrovnik and more. May, June and October are the most popular months to cruise to Sicily and we have over 241 departures available from twelve of the world's leading cruise lines specialising in luxury cruises.
Filter Results
Departures
Show More...
Duration
6 Days
22 Days
Countries Visited
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$900pp
$139,998pp
Countries
Show More...
Filter Results
207 Cruises (241 Cruise Departures)
8 Day Mystical Italy & Croatia with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 June 2027
Visit: Italy, Sicily, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,149
Suite
$10,299
From
US$9,149
Save 9,149
Per Person
View Trip
8 Day Viva Italia with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 23 April 2027
Visit: Italy, Sicily, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,149
Suite
$5,199
From
US$4,149
Save 4,149
Per Person
View Trip
11 Day Islands of the Mediterranean: Spain to Malta with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 25 April 2026
Visit: Spain, Corsica, Sardinia, Sicily, Malta
Inside
-
Oceanview
-
Balcony
-
Suite
$11,845
From
US$11,845
Per Person
View Trip
8 Day Malta, Italy & Spain with Seabourn
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 October 2027
Visit: Greece, Malta, Sicily, Sardinia, Spain
Yours to Explore
Inside
-
Oceanview
-
Balcony
$6,499
Suite
$9,999
From
US$6,499
Per Person
View Trip
11 Day Ancient Civilizations with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 09 February 2028
Visit: Italy, Sicily, Malta, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,199
Suite
$5,699
From
US$3,199
Save 3,199
Per Person
View Trip
12 Day Adriatic, Sicily & the Amalfi Coast with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Venice
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 18 July 2028
Visit: Italy, Sicily, Croatia
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,474
Suite
$18,035
From
US$15,474
Save 2,321
Per Person
View Trip
8 Day A Journey Of Historic Splendour & Stunning Landscapes with Explora Journeys
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2026
Visit: Monaco, Italy, Sicily, Malta, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,650
From
US$5,650
Per Person
View Trip
11 Day Coastal Charisma with Oceania Cruises
Cruise

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 08 March 2028
Visit: Spain, Italy, Sicily, Malta, Greece
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$6,199
From
US$3,599
Save 3,599
Per Person
View Trip
8 Day Italy, Malta, Croatia & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 08 May 2027
Visit: Italy, Sicily, Malta, Croatia, Montenegro
Yours to Explore
Inside
-
Oceanview
-
Balcony
$6,999
Suite
$15,804
From
US$6,999
Per Person
View Trip
9 Day Barcelona to Civitavecchia (Rome) with Silversea
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 21 May 2027
Visit: Spain, Sardinia, Sicily, Malta, Italy
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,900
Suite
$11,000
From
US$6,900
Save 2,500
Per Person
View Trip
11 Day Isle of Beauty, Italian Shores & Malta with Ponant
Cruise

11 Days (10 Nights) Nice to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 19 August 2026
Visit: France, Corsica, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$8,950
Suite
$16,710
From
US$8,950
Per Person
View Trip
12 Day Adriatic, Sicily & the Amalfi Coast with Scenic
New ReleaseCruise

12 Days (11 Nights) Venice to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departures: Jun 2028 to Sep 2028
Visit: Italy, Croatia, Sicily
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,673
Suite
$18,234
From
US$15,673
Save 2,322
Per Person
View Trip
8 Day Stars Of The Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 04 July 2027
Visit: Greece, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,099
Suite
$10,849
From
US$10,099
Save 10,099
Per Person
View Trip
8 Day A Journey of Iconic Islands & Coastal Wonders with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departures: May 2027 to Oct 2027
Visit: Spain, Tunisia, Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$4,700
From
US$4,700
Per Person
View Trip
9 Day Croatia, Malta & Italy with Seabourn
Cruise

9 Days (8 Nights) Venice to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 13 June 2027
Visit: Italy, Croatia, Malta, Sicily
Yours to Explore
Inside
-
Oceanview
-
Balcony
$9,199
Suite
$13,799
From
US$9,199
Per Person
View Trip
8 Day Majestic Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 01 November 2026
Visit: Greece, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,699
Suite
$10,599
From
US$9,699
Save 9,699
Per Person
View Trip
8 Day Exploring Montenegro, Malta & Sicily with Seabourn
Cruise

8 Days (7 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 23 September 2028
Visit: Croatia, Montenegro, Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$5,799
Suite
$9,299
From
US$5,799
Per Person
View Trip
15 Day Sea Of Legacy with Regent Seven Seas
Cruise

15 Days (14 Nights) Trieste to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 29 July 2027
Visit: Italy, Croatia, Greece, Turkey, Sicily
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,599
Suite
$17,299
From
US$16,599
Save 16,599
Per Person
View Trip
10 Day Medieval Mediterranean with Oceania Cruises
Cruise

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 19 February 2028
Visit: Turkey, Greece, Malta, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,699
Suite
$5,299
From
US$2,699
Save 2,699
Per Person
View Trip
8 Day Spotlight On Sparkling Wines with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 October 2026
Visit: Italy, Sicily, Malta, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,949
Suite
$11,399
From
US$10,949
Save 10,949
Per Person
View Trip
7 Day A Journey From The Eternal City To Catalan Shores with Explora Journeys
Cruise

7 Days (6 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 09 June 2026
Visit: Italy, Sicily, Malta, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,130
From
US$5,130
Per Person
View Trip
8 Day Croatia, Montenegro & Italy with Seabourn
Cruise

8 Days (7 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy
Yours to Explore
Inside
-
Oceanview
-
Balcony
$6,899
Suite
$10,499
From
US$6,899
Per Person
View Trip
8 Day Island Odyssey: Malta, Sicily & the Greek Isles with Scenic
New ReleaseCruise

8 Days (7 Nights) Valletta to Athens
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 June 2026
Visit: Malta, Sicily, Greece
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,569
Suite
$13,939
From
US$10,569
Save 1,071
Per Person
View Trip
10 Day Latin Languages Of Love with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 27 March 2028
Visit: Italy, Sicily, Sardinia, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$6,199
From
US$3,599
Save 3,599
Per Person
View Trip
11 Day Rome to Venice with Silversea
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 September 2026
Visit: Italy, Sicily, Montenegro, Croatia
All-Inclusive Fare
Inside
-
Oceanview
$10,700
Balcony
$11,000
Suite
$17,000
From
US$10,700
Per Person
View Trip
12 Day Islands of the Mediterranean with Scenic
New ReleaseCruise

12 Days (11 Nights) Athens to Malaga
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 28 June 2026
Visit: Greece, Sicily, Sardinia, Spain
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,228
Suite
$36,117
From
US$15,228
Save 1,552
Per Person
View Trip
9 Day Monte Carlo to Fusina (Venice) with Silversea
Cruise

9 Days (8 Nights) Monte Carlo to Venice
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 June 2027
Visit: Monaco, Malta, Sicily, Italy, Croatia
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,700
Suite
$11,300
From
US$6,700
Save 1,500
Per Person
View Trip
Results: 181-207 of 207

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Cruises Luxury Cruises Short Break Cruises

Trip Lengths

10 Day 2 Week 3 Week 7 Day

Departure Months

April May June July August September October November December January February March

Cities

Palermo

Cruise Lines Exploring The Med

APT Med Cruises Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations