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Sicily Luxury Cruises

Explore Sicily on one of 171 luxury cruises, departing from Antalya, Athens, Barcelona, Dubrovnik, Florence and more. May, June and October are the most popular months to cruise to Sicily and we have over 198 departures available from eleven of the world's leading cruise lines specialising in luxury cruises.
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171 Cruises (198 Cruise Departures)
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy, France
Inside
$3,199
Oceanview
$2,829
Balcony
$2,939
Suite
$6,292
From
US$2,829
Per Person
View Trip
8 Day Venetian Strongholds with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Oceania Cruises
Departure: 02 June 2026
Visit: Italy, Slovenia, Croatia, Greece, Sicily
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,185
Oceanview
$2,375
Balcony
$3,528
Suite
$4,818
From
US$2,185
Save 2,413
Per Person
View Trip
11 Day The Birth Of Civilization with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 17 November 2027
Visit: Greece, Turkey, Sicily, Italy, Sardinia
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$2,840
Oceanview
$3,665
Balcony
$4,392
Suite
$6,332
From
US$2,840
Save 2,958
Per Person
View Trip
18 Day Discover Scenic Shores and Hidden Gems with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Valletta to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 30 June 2027
Visit: Malta, Sicily, Italy, Corsica, Monaco, France
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
$16,299
Balcony
-
Suite
$21,416
From
US$16,299
Save 17,181
Per Person
View Trip
10 Day Alluring Ancient Ruins with Oceania Cruises
Cruise

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Departure: 15 May 2027
Visit: Turkey, Greece, Sicily, Italy, Sardinia
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,645
Oceanview
$2,887
Balcony
$4,391
Suite
$6,234
From
US$2,645
Save 2,753
Per Person
View Trip
11 Day Islands of the Mediterranean: Spain to Malta with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 25 April 2026
Visit: Spain, Corsica, Sardinia, Sicily, Malta
Wave Offer
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$5,866
Balcony
-
Suite
$8,727
From
US$5,866
Save 10,124
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 May 2026
Visit: Spain, France, Italy, Corsica, Sicily
Inside
$2,629
Oceanview
$2,459
Balcony
$3,169
Suite
$5,896
From
US$2,459
Per Person
View Trip
9 Day Greece, Italy & Spain Cruise: Athens, Siracusa & Malaga with Azamara Cruises
Cruise
 (4)

9 Days (8 Nights) Athens to Malaga
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 26 November 2026
Visit: Greece, Sicily, Malta, Tunisia, Spain
Azamara Always Included
Inside
$1,999
Oceanview
$2,338
Balcony
$3,075
Suite
$4,918
From
US$1,999
Per Person
View Trip
11 Day Ancient jewels of the Mediterranean with Ponant
Cruise

11 Days (10 Nights) Antalya to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departures: Apr 2026 to Apr 2027
Visit: Turkey, Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$7,650
Suite
$14,170
From
US$7,650
Per Person
View Trip
15 Day Sea Of Legacy with Regent Seven Seas
Cruise

15 Days (14 Nights) Venice to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 29 July 2027
Visit: Italy, Croatia, Greece, Turkey, Sicily
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,872
Suite
$13,558
From
US$12,872
Save 20,326
Per Person
View Trip
8 Day Rome to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,560
Suite
$4,240
From
US$4,240
Save 4,160
Per Person
View Trip
9 Day Italy, France & Tunisia with Seabourn
Cruise

9 Days (8 Nights) Genoa to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 April 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,480
Suite
$8,762
From
US$5,480
Save 95
Per Person
View Trip
10 Day Medieval Mediterranean with Oceania Cruises
Cruise

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 19 February 2028
Visit: Turkey, Greece, Malta, Sicily, Italy
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,374
Suite
$5,168
From
US$3,374
Save 3,524
Per Person
View Trip
15 Day Mediterranean, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Inside
$2,399
Oceanview
$2,699
Balcony
$2,909
Suite
$6,164
From
US$2,399
Per Person
View Trip
15 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia, Spain
Inside
$2,629
Oceanview
$2,929
Balcony
$3,579
Suite
$7,905
From
US$2,629
Per Person
View Trip
15 Day Adriatic And Malta with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 30 July 2027
Visit: Italy, Malta, Croatia, Greece, Sicily
Inside
$2,879
Oceanview
$3,279
Balcony
$3,729
Suite
$8,123
From
US$2,879
Per Person
View Trip
10 Day Plazas & Colonnades with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 10 April 2026
Visit: Spain, France, Monaco, Italy, Corsica, Sicily
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$12,461
From
US$12,461
Save 17,337
Per Person
View Trip
15 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (8)

15 Days (14 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Visit: Spain, France, Italy, Sicily, Greece
Azamara Always Included
Exclusive Savings
Inside
$2,969
Oceanview
$3,357
Balcony
$3,861
Suite
$6,344
From
US$2,969
Save 50
Per Person
View Trip
15 Day Mediterranean And Croatia with Cunard
Cruise
 (13)

15 Days (14 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 04 June 2027
Visit: Italy, Croatia, Sicily, Spain, Corsica
Inside
$2,359
Oceanview
$2,679
Balcony
$3,199
Suite
$6,648
From
US$2,359
Per Person
View Trip
15 Day Sunlight & Stone with Regent Seven Seas
Cruise

15 Days (14 Nights) Venice to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 16 September 2027
Visit: Italy, Croatia, Greece, Turkey, Sicily
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,460
Suite
$13,754
From
US$13,460
Save 20,938
Per Person
View Trip
14 Day Turkey, Egypt & Italy Cruise: Ephesus, Alexandria & Amalfi Coast with Azamara Cruises
Cruise
 (3)

14 Days (13 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 21 November 2027
Visit: Greece, Turkey, Egypt, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$3,368
Oceanview
$4,153
Balcony
$5,181
Suite
$7,509
From
US$3,368
Save 71
Per Person
View Trip
15 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Istanbul to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy, Croatia
Inside
$2,869
Oceanview
$3,219
Balcony
$3,919
Suite
$8,491
From
US$2,869
Per Person
View Trip
15 Day Adriatic And Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 06 July 2026
Visit: Italy, Croatia, Malta, Sicily, France
Inside
$2,319
Oceanview
$2,379
Balcony
$2,739
Suite
$6,193
From
US$2,319
Per Person
View Trip
21 Day Barcelona to Rome with Silversea
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 September 2026
Visit: Spain, France, Monaco, Corsica, Italy, Sicily
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$12,200
Suite
$18,400
From
US$12,200
Per Person
View Trip
9 Day Barcelona to Civitavecchia (Rome) with Silversea
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 21 May 2027
Visit: Spain, Sardinia, Sicily, Malta, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,530
Suite
$8,110
From
US$5,530
Save 2,370
Per Person
View Trip
11 Day 10th Annual Piano Festival at Sea with Ponant
Cruise

11 Days (10 Nights) Valletta to Antalya
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departures: Mar 2026 to Apr 2027
Visit: Malta, Sicily, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$7,650
Suite
$14,170
From
US$7,650
Per Person
View Trip
8 Day Barcelona to Rome with Silversea
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 07 September 2026
Visit: Spain, Sardinia, Tunisia, Sicily, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$5,280
Balcony
$6,160
Suite
$8,410
From
US$5,280
Save 1,320
Per Person
View Trip
9 Day Dalmatian Rhapsody with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 25 May 2027
Visit: Italy, Sicily, Montenegro, Croatia, Slovenia
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,484
Suite
$7,366
From
US$6,484
Save 11,714
Per Person
View Trip
15 Day Harbors Of Heritage with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 22 July 2027
Visit: Italy, Sicily, Montenegro, Croatia, Greece
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,655
Suite
$13,900
From
US$13,655
Save 21,143
Per Person
View Trip
11 Day Italian Celebration with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 May 2027
Visit: Spain, France, Monaco, Italy, Sicily, Sardinia
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,644
Suite
$9,673
From
US$8,644
Save 14,954
Per Person
View Trip
Results: 121-150 of 171

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