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Sicily Luxury Cruises

Explore Sicily on one of 192 luxury cruises, departing from Antalya, Athens, Barcelona, Bologna, Dubrovnik and more. October is the most popular month to cruise to Sicily and we have over 222 departures available from twelve of the world's leading cruise lines specialising in luxury cruises.
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192 Cruises (222 Cruise Departures)
8 Day A Journey Of Adriatic Shores & Mediterranean Legends with Explora Journeys
Cruise

8 Days (7 Nights) Venice to Rome
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 08 April 2028
Visit: Italy, Croatia, Montenegro, Malta, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$4,640
From
US$4,640
Per Person
View Trip
10 Day Latin Languages Of Love with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 27 March 2028
Visit: Italy, Sicily, Sardinia, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,599
Suite
$6,199
From
US$3,599
Save 3,599
Per Person
View Trip
11 Day Yachting Sicily to Elba via the Amalfi Coast with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Valletta to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 30 June 2027
Visit: Italy, Sicily, Malta
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$8,247
Balcony
-
Suite
$11,037
From
US$8,247
Save 1,898
Per Person
View Trip
15 Day A Holiday To Remember with Oceania Cruises
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 20 December 2027
Visit: Spain, Morocco, Tunisia, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,199
Suite
$8,499
From
US$6,199
Save 6,199
Per Person
View Trip
8 Day Viva Italia with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 23 April 2027
Visit: Italy, Sicily, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,449
Suite
$5,499
From
US$4,449
Save 4,449
Per Person
View Trip
11 Day Italian Celebration with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 May 2027
Visit: Spain, France, Monaco, Italy, Sicily, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,849
Suite
$15,199
From
US$13,849
Save 13,849
Per Person
View Trip
9 Day Peaceful Islands and Ancient Treasures of the Mediterranean with Ponant
Cruise

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 14 June 2027
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$7,300
Suite
$13,630
From
US$7,300
Per Person
View Trip
8 Day Majestic Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 01 November 2026
Visit: Greece, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,499
Suite
$10,449
From
US$9,499
Save 9,499
Per Person
View Trip
11 Day Fusina (Venice) to Nice with Silversea
Cruise

11 Days (10 Nights) Venice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 07 May 2027
Visit: Italy, Croatia, Sicily, Malta, France
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$7,000
Balcony
$8,300
Suite
$13,200
From
US$7,000
Save 1,500
Per Person
View Trip
8 Day Heaven On The Med with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 22 July 2027
Visit: Italy, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,399
Suite
$9,749
From
US$9,399
Save 9,399
Per Person
View Trip
8 Day Ancient Cities of the Mediterranean with Ponant
Cruise

8 Days (7 Nights) Athens to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 22 October 2026
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$6,590
Suite
$12,350
From
US$6,590
Per Person
View Trip
9 Day Centuries Of Art with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 02 September 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,399
Suite
$10,399
From
US$9,399
Save 9,399
Per Person
View Trip
17 Day An Extended Journey Of Island Chic & Riviera Glamour with Explora Journeys
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 05 October 2026
Visit: Italy, Monaco, France, Spain, Sicily
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$13,770
From
US$13,770
Per Person
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Tour + Cruise

12 Days Malta to Rome
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: May 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$12,990
Suite
$16,990
From
US$12,990
Per Person
View Trip
10 Day Ancient Shores of the Mediterranean with Ponant
Cruise

10 Days (9 Nights) Valletta to Malaga
Cruise Line: Ponant
Ships: Le Bougainville, Le Champlain (+2 more), Le Dumont d’Urville, Le Laperouse
Departures: Oct 2026 to Nov 2027
Visit: Malta, Sicily, Tunisia, Algeria, Spain
Inside
-
Oceanview
-
Balcony
$7,760
Suite
$14,470
From
US$7,760
Per Person
View Trip
12 Day Rome, the Amalfi Coast & Sicily with Tauck
Tour + Cruise

12 Days Rome to Malta
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: May 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$12,990
Suite
$16,990
From
US$12,990
Per Person
View Trip
8 Day A Journey Across Mediterranean Masterpieces with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 06 July 2026
Visit: Spain, Tunisia, Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$5,625
From
US$5,625
Per Person
View Trip
12 Day Adriatic, Sicily & the Amalfi Coast with Scenic
New ReleaseCruise

12 Days (11 Nights) Rome to Venice
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 18 July 2028
Visit: Italy, Sicily, Croatia
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,474
Suite
$18,035
From
US$15,474
Save 2,321
Per Person
View Trip
11 Day Ancient jewels of the Mediterranean with Ponant
Cruise

11 Days (10 Nights) Antalya to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 23 April 2027
Visit: Turkey, Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$8,140
Suite
$15,130
From
US$8,140
Per Person
View Trip
9 Day Mediterranean Islands with Seabourn
Cruise

9 Days (8 Nights) Rome to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily
Inside
-
Oceanview
-
Balcony
$7,819
Suite
$11,899
From
US$7,819
Per Person
View Trip
11 Day A Journey through Mediterranean Wonders & Ancient Echoes with Explora Journeys
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 March 2027
Visit: Spain, Italy, Malta, Tunisia, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$5,590
From
US$5,590
Per Person
View Trip
8 Day A Journey Through Fortresses, Medinas and Balearic Splendour with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 02 January 2028
Visit: Italy, Sicily, Malta, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$4,735
From
US$4,735
Per Person
View Trip
8 Day Fusina (Venice) to Monte Carlo with Silversea
Cruise

8 Days (7 Nights) Venice to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 September 2027
Visit: Italy, Croatia, Sicily, Monaco
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,200
Suite
$10,500
From
US$6,200
Save 2,500
Per Person
View Trip
11 Day Monte Carlo to Rome with Silversea
Cruise

11 Days (10 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 08 October 2026
Visit: Monaco, France, Corsica, Italy, Sicily
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,400
Suite
$13,700
From
US$9,400
Save 1,500
Per Person
View Trip
15 Day Sunlight & Stone with Regent Seven Seas
Cruise

15 Days (14 Nights) Trieste to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 16 September 2027
Visit: Italy, Croatia, Greece, Turkey, Sicily
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$20,149
From
US$20,149
Save 20,149
Per Person
View Trip
12 Day Adriatic, Sicily & the Amalfi Coast with Scenic
New ReleaseCruise

12 Days (11 Nights) Venice to Rome
Cruise Line: Scenic
Ship: Scenic Ikon
Departures: Jun 2028 to Sep 2028
Visit: Italy, Croatia, Sicily
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,673
Suite
$18,234
From
US$15,673
Save 2,390
Per Person
View Trip
8 Day Under Sail from Sicily to the Greek Islands with Ponant
Cruise

8 Days (7 Nights) Palermo to Athens
Cruise Line: Ponant
Ship: Le Ponant
Departure: 08 June 2027
Visit: Sicily, Italy, Greece
Inside
-
Oceanview
$12,050
Balcony
$19,470
Suite
$21,690
From
US$12,050
Per Person
View Trip
11 Day 10th Annual Piano Festival at Sea with Ponant
Cruise

11 Days (10 Nights) Valletta to Antalya
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 13 April 2027
Visit: Malta, Sicily, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$10,050
Suite
$17,040
From
US$10,050
Per Person
View Trip
8 Day Fusina (Venice) to Monte Carlo with Silversea
Cruise

8 Days (7 Nights) Venice to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 August 2027
Visit: Italy, Croatia, Sicily, Malta, Monaco
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,100
Suite
$8,100
From
US$5,100
Save 2,500
Per Person
View Trip
8 Day Pompeii, Sicily, Malta & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Monte Carlo to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 17 June 2028
Visit: Monaco, Italy, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$5,219
Suite
$8,369
From
US$5,219
Per Person
View Trip
Results: 121-150 of 192

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