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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 384 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bologna and more. October is the most popular month to cruise to Sicily and we have over 2,193 departures available from twenty-four of the world's leading cruise lines.
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384 Cruises (2,193 Cruise Departures)
19 Day Italy Intensive Cruise: Taranto, Amalfi & Sorrento with Azamara Cruises
Cruise
 (8)

19 Days (18 Nights) Venice to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 May 2027
Visit: Italy, Montenegro, Sicily, France, Spain
Azamara Always Included
Inside
$5,529
Oceanview
$5,959
Balcony
-
Suite
$11,059
From
US$5,529
Per Person
View Trip
11 Day Eastbound Adventure with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 18 October 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,149
Oceanview
$3,949
Balcony
$4,699
Suite
$6,699
From
US$3,149
Save 3,149
Per Person
View Trip
15 Day Cities of Antiquity with Viking Cruises
Cruise
 (6)

15 Days (14 Nights) Rome to Athens
Cruise Line: Viking Cruises
Ships: Viking Star, Viking Vela
Departures: Jan 2027 to Dec 2027
Visit: Italy, Sicily, Malta, Greece
Viking $799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,099
Suite
$6,999
From
US$4,099
Save 1,500
Per Person
View Trip
8 Day Amalfi Coast, Africa & Iberia with Viking Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Libra (+5 more), Viking Neptune, Viking Saturn, Viking Star, Viking Vela, Viking Vesta
Departures: Oct 2026 to Jun 2028
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,999
Suite
$3,999
From
US$2,999
Save 300
Per Person
View Trip
8 Day Italy, Algeria & Spain Cruise: Trapani, Algiers & Granada with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Malaga
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 02 December 2027
Visit: Italy, Sicily, Tunisia, Algeria, Spain
Azamara Always Included
Inside
$1,739
Oceanview
$1,959
Balcony
$2,619
Suite
$3,749
From
US$1,739
Per Person
View Trip
15 Day Mediterranean & Italian Sojourn with Viking Cruises
Cruise
 (1)

15 Days (14 Nights) Venice to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Lyra (+8 more), Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Sep 2026 to Sep 2028
Visit: Italy, Croatia, Sicily, Monaco, France, Spain
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,998
Suite
$8,998
From
US$6,998
Save 2,200
Per Person
View Trip
13 Day Minarets & Mosaics with Oceania Cruises
Cruise
 (2)

13 Days (12 Nights) Athens to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 05 July 2026
Visit: Greece, Turkey, Tunisia, Sicily, Monaco
Memorial Day Sale
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$2,880
Balcony
$4,110
Suite
$5,610
From
US$2,880
Save 6,718
Per Person
View Trip
11 Day Italy Intensive Cruise: Florence, Sorrento & Venice with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 August 2028
Visit: Italy, Sicily, Montenegro
Azamara Always Included
Inside
$3,389
Oceanview
$3,679
Balcony
$4,519
Suite
$6,379
From
US$3,389
Per Person
View Trip
22 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 14 September 2026
Visit: Italy, France, Sicily, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$7,099
Suite
-
From
US$7,099
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Oct 2027
Visit: Malta, Spain, France, Italy, Sicily
Inside
$875
Oceanview
$1,015
Balcony
$1,115
Suite
$2,105
From
US$875
Per Person
View Trip
12 Day Civitavecchia (Rome) to Lavrion (Athens) with Silversea
Cruise
 (1)

12 Days (11 Nights) Rome to Athens
Cruise Line: Silversea
Ship: Silver Nova
Departure: 24 June 2026
Visit: Italy, Sicily, Malta, Greece
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,600
Suite
$19,600
From
US$10,600
Save 1,500
Per Person
View Trip
8 Day Italy & Malta Cruise with Celebrity Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 04 November 2027
Visit: Spain, Italy, Sicily, Malta
Exclusive Savings
Inside
$1,012
Oceanview
$1,268
Balcony
$1,140
Suite
$4,232
From
US$1,012
Save 600
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Jan 2028
Visit: Sicily, Malta, Spain, France, Italy
Inside
$791
Oceanview
$951
Balcony
$1,081
Suite
$1,601
From
US$791
Per Person
View Trip
15 Day Ancient Mediterranean Antiquities with Viking Cruises
Cruise
 (6)

15 Days (14 Nights) Rome to Istanbul
Cruise Line: Viking Cruises
Ships: Viking Mira, Viking Neptune (+3 more), Viking Star, Viking Vela, Viking Vesta
Departures: Oct 2026 to Feb 2028
Visit: Italy, Sicily, Greece, Turkey
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$5,098
Suite
$6,698
From
US$5,098
Save 1,700
Per Person
View Trip
8 Day Ancient Sites & Cities with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 November 2026
Visit: Italy, Sicily, Malta, Greece, Turkey
Memorial Day Sale
Your World Inclusions
Exclusive Savings
Inside
$2,000
Oceanview
$2,040
Balcony
$3,000
Suite
$3,920
From
US$2,000
Save 2,998
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Mar 2027 to Jan 2028
Visit: France, Italy, Sicily, Malta, Spain
Inside
$791
Oceanview
$951
Balcony
$1,081
Suite
$1,601
From
US$791
Per Person
View Trip
10 Day Italy & Greece Cruise: Amalfi, Crete & Santorini with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Rome to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 August 2027
Visit: Italy, Sicily, Greece, Turkey
Azamara Always Included
Inside
$3,819
Oceanview
$4,319
Balcony
$5,279
Suite
$7,699
From
US$3,819
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 06 November 2026
Visit: France, Italy, Sicily, Spain
Inside
$1,010
Oceanview
$1,180
Balcony
$1,350
Suite
$1,820
From
US$1,010
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

21 Days (20 Nights) Rio de Janeiro to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 April 2027
Visit: Brazil, Spain, France, Italy, Sicily
Inside
-
Oceanview
$1,669
Balcony
$2,219
Suite
-
From
US$1,669
Per Person
View Trip
8 Day Spain, Italy And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 04 June 2027
Visit: Italy, Croatia, Sicily, Spain
Bonus Onboard Credit
Value Fare
Inside
$1,309
Oceanview
$1,429
Balcony
$1,669
Suite
$3,399
From
US$1,309
Per Person
View Trip
15 Day Mediterranean & Adriatic Odyssey with Viking Cruises
New ReleaseCruise
 (6)

15 Days (14 Nights) Rome to Athens
Cruise Line: Viking Cruises
Ships: Viking Neptune, Viking Star
Departures: Nov 2026 to Feb 2028
Visit: Italy, Sicily, Croatia, Greece
Viking $799 Air Deal
Viking $999 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,899
Suite
$6,999
From
US$4,899
Save 2,500
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$619
Oceanview
$1,679
Balcony
$1,019
Suite
$1,319
From
US$619
Per Person
View Trip
15 Day Mediterranean & Italian Sojourn with Viking Cruises
Cruise
 (1)

15 Days (14 Nights) Barcelona to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Feb 2027 to Jul 2028
Visit: Spain, France, Monaco, Italy, Sicily, Croatia
Viking $999 Air Deal
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,998
Suite
$9,498
From
US$6,998
Save 1,700
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Mar 2028
Visit: Italy, Sicily, Tunisia, Spain, France
Inside
$588
Oceanview
$695
Balcony
$795
Suite
$1,535
From
US$588
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 13 July 2026
Visit: Turkey, Greece, Malta, Sicily, Italy
Inside
$1,869
Oceanview
$2,069
Balcony
$2,469
Suite
$3,069
From
US$1,869
Per Person
View Trip
8 Day Majestic Medieval Fortresses with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 15 October 2027
Visit: Italy, Croatia, Greece, Sicily
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$1,899
Oceanview
$2,099
Balcony
$3,399
Suite
$4,899
From
US$1,899
Save 1,899
Per Person
View Trip
10 Day Western Med: Barcelona to Rome with Virgin Voyages
Cruise
 (5)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 08 August 2027
Visit: Spain, France, Italy, Sicily, Malta
Inside
$2,407
Oceanview
$2,790
Balcony
$2,875
Suite
-
From
US$2,407
Per Person
View Trip
15 Day Adriatic And Malta with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 30 July 2027
Visit: Italy, Malta, Croatia, Greece, Sicily
Cunard Fare
Value Fare
Inside
$2,929
Oceanview
$3,279
Balcony
$3,729
Suite
$8,199
From
US$2,929
Per Person
View Trip
8 Day Italy, Greece And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 September 2028
Visit: Italy, Croatia, Greece, Sicily, Spain
Cunard Fare
Value Fare
Inside
$1,704
Oceanview
$1,929
Balcony
$2,379
Suite
$4,314
From
US$1,704
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Florence to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 09 November 2027
Visit: Italy, Sicily, Malta, Spain, France
Inside
$1,013
Oceanview
$1,173
Balcony
$1,303
Suite
$1,823
From
US$1,013
Per Person
View Trip
Results: 121-150 of 384

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