Home > Cruises > Europe Cruises > Mediterranean Cruises > Sicily Cruises

Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 405 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. October is the most popular month to cruise to Sicily and we have over 2,306 departures available from twenty-four of the world's leading cruise lines.
Filter Results
Departures
Show More...
Duration
5 Days
23 Days
Countries Visited
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$300pp
$139,998pp
Countries
Show More...
Filter Results
405 Cruises (2,306 Cruise Departures)
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 05 May 2026
Visit: Spain, Tunisia, Sicily, Italy
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
$629
Suite
$1,959
From
US$629
Per Person
View Trip
8 Day Mykonos Moons and Italian Sunrises with Virgin Voyages
Cruise
 (1)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 04 October 2026
Visit: Greece, Sicily, Italy, Spain
Limited Time Offer
Inside
-
Oceanview
-
Balcony
$2,443
Suite
$3,983
From
US$2,443
Per Person
View Trip
12 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departures: Jun 2026 to Aug 2026
Visit: Italy, Sicily, Montenegro, Croatia
Bonus Onboard Credit
Exclusive Savings
Inside
$1,674
Oceanview
$1,724
Balcony
$2,899
Suite
$4,848
From
US$2,527
Per Person
View Trip
12 Day Civitavecchia (Rome) to Lavrion (Athens) with Silversea
Cruise
 (1)

12 Days (11 Nights) Rome to Athens
Cruise Line: Silversea
Ship: Silver Nova
Departure: 24 June 2026
Visit: Italy, Sicily, Malta, Greece
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,600
Suite
$15,600
From
US$10,600
Save 1,500
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Sep 2027
Visit: Spain, France, Italy, Sicily
Inside
$599
Oceanview
-
Balcony
$899
Suite
$1,069
From
US$599
Per Person
View Trip
10 Day Italy & Greece Cruise with Celebrity Cruises
Cruise
 (3)

10 Days (9 Nights) Barcelona to Athens
Cruise Line: Celebrity Cruises
Ship: Celebrity Infinity
Departure: 01 April 2028
Visit: Spain, Italy, Sicily, Greece
Bonus Onboard Credit
Exclusive Savings
Inside
$1,532
Oceanview
$1,772
Balcony
$2,342
Suite
$4,952
From
US$2,268
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: France, Italy, Sicily, Spain
Inside
$851
Oceanview
$921
Balcony
$1,041
Suite
-
From
US$851
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$824
Oceanview
$924
Balcony
$1,104
Suite
-
From
US$824
Per Person
View Trip
15 Day Ancient Mediterranean Antiquities with Viking Cruises
Cruise
 (6)

15 Days (14 Nights) Istanbul to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+7 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Nov 2026 to Apr 2028
Visit: Turkey, Greece, Sicily, Italy
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$4,998
Suite
$6,998
From
US$4,998
Save 1,900
Per Person
View Trip
8 Day Greece And Turkey with Cunard
Cruise
 (13)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Inside
$1,319
Oceanview
$1,429
Balcony
$1,549
Suite
$3,229
From
US$1,319
Per Person
View Trip
11 Day Italy, Spain & Malta Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 20 October 2026
Visit: Spain, Italy, Malta, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,323
Oceanview
-
Balcony
$1,923
Suite
$5,950
From
US$1,967
Per Person
View Trip
8 Day Italy, Croatia & Malta Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Bologna
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 19 October 2026
Visit: Italy, Sicily, Malta, Croatia
Exclusive Savings
Inside
$1,117
Oceanview
$1,416
Balcony
$2,269
Suite
$4,459
From
US$1,117
Save 566
Per Person
View Trip
11 Day Italy & French Riviera with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departures: May 2026 to Oct 2026
Visit: Spain, Italy, Sicily, France
Bonus Onboard Credit
Exclusive Savings
Inside
$1,974
Oceanview
$2,222
Balcony
$3,049
Suite
$6,399
From
US$3,035
Per Person
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Athens
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 31 May 2027
Visit: Spain, Sicily, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$1,311
Oceanview
$1,691
Balcony
$1,934
Suite
$2,544
From
US$1,875
Save 50
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Italy, Sicily, Spain, France
Inside
$776
Oceanview
$876
Balcony
$1,056
Suite
-
From
US$776
Per Person
View Trip
8 Day Greece, Italy & Turkey Cruise with Celebrity Cruises
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 21 August 2027
Visit: Greece, Turkey, Sicily, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,634
Oceanview
$1,785
Balcony
$2,164
Suite
$7,293
From
US$2,452
Per Person
View Trip
8 Day Greece, Italy And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 22 October 2027
Visit: Italy, Greece, Sicily, Spain
Inside
$1,399
Oceanview
$1,599
Balcony
$1,899
Suite
$4,049
From
US$1,399
Per Person
View Trip
10 Day Trojan Trek Revisited with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 July 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,899
Oceanview
$3,149
Balcony
$4,799
Suite
$6,699
From
US$2,899
Save 2,899
Per Person
View Trip
11 Day Best Of Italy & Greece Cruise with Celebrity Cruises
Cruise
 (2)

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 10 September 2027
Visit: Spain, Italy, Sicily, Greece
Bonus Onboard Credit
Exclusive Savings
Inside
$1,997
Oceanview
$2,540
Balcony
$2,337
Suite
$8,504
From
US$2,971
Per Person
View Trip
15 Day Cities of Antiquity with Viking Cruises
Cruise
 (6)

15 Days (14 Nights) Athens to Rome
Cruise Line: Viking Cruises
Ship: Viking Star
Departure: 22 December 2026
Visit: Greece, Malta, Sicily, Italy
Viking $799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,099
Suite
$6,499
From
US$4,099
Save 1,500
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 24 October 2026
Visit: Spain, France, Italy, Sicily
Inside
$413
Oceanview
-
Balcony
-
Suite
-
From
US$413
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 13 June 2027
Visit: Spain, France, Italy, Sicily
Inside
$1,339
Oceanview
$1,939
Balcony
$1,939
Suite
$2,129
From
US$1,339
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2026 to Nov 2026
Visit: Spain, France, Italy, Sicily
Inside
$860
Oceanview
$1,030
Balcony
$1,240
Suite
$1,740
From
US$860
Per Person
View Trip
8 Day Stars Of The Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 04 July 2027
Visit: Greece, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,099
Suite
$10,849
From
US$10,099
Save 10,099
Per Person
View Trip
15 Day Ancient Mediterranean Antiquities with Viking Cruises
Cruise
 (6)

15 Days (14 Nights) Rome to Istanbul
Cruise Line: Viking Cruises
Ships: Viking Mira, Viking Neptune (+4 more), Viking Saturn, Viking Star, Viking Vela, Viking Vesta
Departures: Oct 2026 to Feb 2028
Visit: Italy, Sicily, Greece, Turkey
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$5,098
Suite
$6,998
From
US$5,098
Save 1,900
Per Person
View Trip
12 Day Italy Intensive Cruise: Florence, Sorrento & Sicily with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Nice to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 September 2027
Visit: France, Italy, Sicily, Montenegro
Azamara Always Included
Inside
$5,589
Oceanview
$6,249
Balcony
$7,519
Suite
$10,789
From
US$5,589
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy
Bonus Onboard Credit
Inside
$1,359
Oceanview
$1,409
Balcony
$1,779
Suite
-
From
US$1,359
Per Person
View Trip
11 Day Iconic Greek Isles with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 09 July 2027
Visit: Turkey, Greece, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,299
Oceanview
$3,749
Balcony
$5,399
Suite
$7,499
From
US$3,299
Save 3,299
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Bari to Valencia
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 24 October 2026
Visit: Italy, Greece, Sicily, Spain
Inside
$935
Oceanview
$1,145
Balcony
$1,565
Suite
$1,795
From
US$935
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Aug 2026 to Sep 2026
Visit: Spain, France, Italy, Sicily
Inside
$869
Oceanview
-
Balcony
$1,199
Suite
$1,549
From
US$869
Per Person
View Trip
Results: 121-150 of 405

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Cruises Luxury Cruises Short Break Cruises

Trip Lengths

10 Day 2 Week 3 Week 7 Day

Departure Months

April May June July August September October November December January February March

Cities

Palermo

Cruise Lines Exploring The Med

APT Med Cruises Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations