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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 384 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bologna and more. October is the most popular month to cruise to Sicily and we have over 2,193 departures available from twenty-four of the world's leading cruise lines.
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384 Cruises (2,193 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Messina to Messina
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Nov 2026 to Mar 2028
Visit: Sicily, Malta, Spain, France, Italy
Inside
$706
Oceanview
$906
Balcony
$1,006
Suite
$1,766
From
US$706
Per Person
View Trip
8 Day Mediterranean, Croatia And Greece with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 16 June 2028
Visit: Italy, Croatia, Greece, Sicily, Spain
Cunard Fare
Value Fare
Inside
$1,704
Oceanview
$1,929
Balcony
$2,379
Suite
$4,314
From
US$1,704
Per Person
View Trip
15 Day Mediterranean, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Bonus Onboard Credit
Value Fare
Inside
$2,399
Oceanview
$2,699
Balcony
$2,859
Suite
$6,119
From
US$2,399
Per Person
View Trip
11 Day Visions Of Byzantium with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 17 August 2026
Visit: Spain, Sicily, Greece, Turkey
Memorial Day Sale
Your World Inclusions
Exclusive Savings
Inside
$2,587
Oceanview
$2,775
Balcony
$4,125
Suite
$5,100
From
US$2,587
Save 4,311
Per Person
View Trip
11 Day Rome, Florence, Mykonos & More with Virgin Voyages
Cruise
 (1)

11 Days (10 Nights) Rome to Athens
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 31 August 2026
Visit: Italy, Sicily, Greece
Inside
$2,790
Oceanview
$3,190
Balcony
$3,790
Suite
$5,990
From
US$2,790
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 27 May 2026
Visit: Italy, Sicily, Malta, Greece, Turkey
Inside
$1,319
Oceanview
$1,359
Balcony
$1,489
Suite
$3,139
From
US$1,319
Per Person
View Trip
8 Day Mykonos Moons and Italian Sunrises with Virgin Voyages
Cruise
 (1)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 04 October 2026
Visit: Greece, Sicily, Italy, Spain
Inside
$2,142
Oceanview
-
Balcony
$2,605
Suite
$11,445
From
US$2,605
Per Person
View Trip
12 Day Greece & Italy Cruise: Rhodes, Crete & Amalfi with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 26 July 2028
Visit: Greece, Turkey, Sicily, Italy
Azamara Always Included
Inside
$3,379
Oceanview
$3,659
Balcony
$4,519
Suite
$6,389
From
US$3,379
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 05 November 2026
Visit: Spain, France, Italy, Sicily
Inside
$1,006
Oceanview
$1,116
Balcony
$1,286
Suite
$1,796
From
US$1,006
Per Person
View Trip
11 Day Made in Italy, the Luxury Edition with Ponant
Cruise
 (2)

11 Days (10 Nights) Florence to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 08 September 2027
Visit: Italy, Sicily
Inside
-
Oceanview
$16,120
Balcony
$17,010
Suite
$35,560
From
US$16,120
Per Person
View Trip
11 Day Greece, Italy & Malta Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Oct 2026 to Nov 2026
Visit: Spain, Malta, Greece, Sicily, Italy
Exclusive Savings
Inside
$1,212
Oceanview
$1,366
Balcony
$1,652
Suite
$4,415
From
US$1,212
Save 718
Per Person
View Trip
8 Day Italy, Greece And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 07 July 2028
Visit: Italy, Croatia, Greece, Sicily
Cunard Fare
Value Fare
Inside
$1,649
Oceanview
$1,784
Balcony
$2,144
Suite
$4,169
From
US$1,649
Per Person
View Trip
8 Day Italy And Adriatic with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Visit: Spain, Italy, Sicily, Greece, Montenegro
Inside
$899
Oceanview
$1,099
Balcony
$2,269
Suite
$3,009
From
US$899
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2027 to May 2027
Visit: Italy, Sicily, France, Spain
Inside
$1,159
Oceanview
$1,549
Balcony
$1,599
Suite
$1,779
From
US$1,159
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Mar 2028
Visit: Italy, Sicily, Tunisia, Spain, France
Inside
$588
Oceanview
$695
Balcony
$795
Suite
$1,535
From
US$588
Per Person
View Trip
8 Day Italy & France Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 03 August 2026
Visit: Spain, France, Corsica, Italy, Sicily
Exclusive Savings
Inside
$1,236
Oceanview
$1,340
Balcony
$1,688
Suite
$2,389
From
US$1,236
Save 656
Per Person
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Athens
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 17 August 2026
Visit: Italy, Sicily, Greece, Turkey
Exclusive Savings
Inside
$1,887
Oceanview
$1,998
Balcony
$2,092
Suite
$4,106
From
US$1,887
Save 909
Per Person
View Trip
15 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Istanbul to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy, Croatia
Value Fare
Inside
$2,869
Oceanview
$3,219
Balcony
$3,919
Suite
$8,569
From
US$2,869
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 08 November 2027
Visit: France, Italy, Sicily, Malta, Spain
Inside
$1,021
Oceanview
$1,181
Balcony
$1,311
Suite
$1,831
From
US$1,021
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Virgin Voyages
Cruise
 (5)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departures: May 2027 to Sep 2027
Visit: Spain, France, Italy, Sicily
Inside
$1,323
Oceanview
$1,673
Balcony
$1,743
Suite
$4,200
From
US$1,323
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Oct 2026
Visit: Italy, Sicily, Spain, France
Inside
$1,113
Oceanview
$1,225
Balcony
$1,385
Suite
$1,865
From
US$1,113
Per Person
View Trip
15 Day Mediterranean & Italian Sojourn with Viking Cruises
Cruise
 (1)

15 Days (14 Nights) Barcelona to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Feb 2027 to Jul 2028
Visit: Spain, France, Monaco, Italy, Sicily, Croatia
Viking $999 Air Deal
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,998
Suite
$9,498
From
US$6,998
Save 1,700
Per Person
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Athens
Cruise Line: Royal Caribbean
Ships: Brilliance of the Seas, Explorer of the Seas
Departures: May 2026 to Sep 2027
Visit: Italy, Sicily, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$1,116
Oceanview
$1,546
Balcony
$1,878
Suite
$2,453
From
US$1,116
Save 981
Per Person
View Trip
12 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departures: Jun 2026 to Aug 2026
Visit: Italy, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
$1,288
Oceanview
$1,608
Balcony
$2,374
Suite
$4,399
From
US$1,288
Save 985
Per Person
View Trip
8 Day History & Heritage with Regent Seven Seas
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 05 August 2027
Visit: Greece, Turkey, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,799
Suite
$9,149
From
US$8,799
Save 8,799
Per Person
View Trip
8 Day A Journey Through Italy's Timeless Wonders to Istanbul's Vibrant Soul with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 04 December 2027
Visit: Italy, Sicily, Greece, Turkey
Inside
-
Oceanview
-
Balcony
-
Suite
$4,550
From
US$4,550
Per Person
View Trip
12 Day Rome, the Amalfi Coast & Sicily with Tauck
Tour + Cruise

12 Days Rome to Malta
Operated By: Tauck
Ships: Le Bougainville, Le Dumont d’Urville
Departures: May 2026 to Oct 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$12,990
Suite
$16,990
From
US$12,990
Per Person
View Trip
8 Day Majestic Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 01 November 2026
Visit: Greece, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,499
Suite
$10,449
From
US$9,499
Save 9,499
Per Person
View Trip
8 Day Adriatic & Greece From Bologna To Rome with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Bologna to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departures: Jul 2026 to Sep 2026
Visit: Italy, Croatia, Montenegro, Greece, Sicily
Inside
$979
Oceanview
$1,059
Balcony
$1,529
Suite
$1,709
From
US$979
Per Person
View Trip
10 Day Greece & Italy Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Mariner of the Seas
Departure: 28 August 2027
Visit: Italy, Greece, Sicily, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,528
Oceanview
$1,998
Balcony
$2,378
Suite
$3,713
From
US$1,528
Save 727
Per Person
View Trip
Results: 181-210 of 384

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