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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 357 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. October is the most popular month to cruise to Sicily and we have over 2,318 departures available from twenty-four of the world's leading cruise lines.
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357 Cruises (2,318 Cruise Departures)
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 05 May 2026
Visit: Spain, Tunisia, Sicily, Italy
Inside
$619
Oceanview
$589
Balcony
-
Suite
-
From
US$589
Per Person
View Trip
12 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 18 May 2026
Visit: Italy, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
$2,898
Oceanview
$3,824
Balcony
$5,179
Suite
$10,588
From
US$2,898
Save 1,736
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC World Asia, MSC World Europa
Departures: Apr 2026 to Oct 2027
Visit: Spain, France, Italy, Sicily, Malta
Bonus Onboard Credit
Exclusive Savings
Inside
$726
Oceanview
$846
Balcony
$986
Suite
$1,716
From
US$726
Save 52
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Virtuosa
Departures: May 2026 to Nov 2027
Visit: France, Spain, Tunisia, Sicily, Italy
Bonus Onboard Credit
Inside
$836
Oceanview
$1,060
Balcony
$1,217
Suite
$2,159
From
US$836
Per Person
View Trip
10 Day Italian Shores and Isle of Beauty with Ponant
Cruise
 (2)

10 Days (9 Nights) Valletta to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 June 2027
Visit: Malta, Sicily, Italy, Corsica, France
Inside
-
Oceanview
$7,090
Balcony
$7,470
Suite
$13,900
From
US$7,090
Per Person
View Trip
11 Day Ancient Civilizations with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 09 February 2028
Visit: Italy, Sicily, Malta, Greece, Turkey
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,129
Suite
$5,554
From
US$3,129
Save 3,269
Per Person
View Trip
15 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Istanbul to Trieste
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 08 October 2027
Visit: Turkey, Greece, Sicily, Italy, Croatia
Inside
$2,869
Oceanview
$3,219
Balcony
$3,919
Suite
$8,491
From
US$2,869
Per Person
View Trip
10 Day Western Med: Barcelona to Rome with Virgin Voyages
Cruise
 (5)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 08 August 2027
Visit: Spain, France, Italy, Sicily, Malta
With Love From the World
Inside
$1,881
Oceanview
$2,151
Balcony
$2,331
Suite
$5,535
From
US$1,881
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departures: Sep 2026 to Aug 2027
Visit: Turkey, Greece, Malta, Sicily, Italy
Exclusive Savings
Inside
$2,299
Oceanview
$2,736
Balcony
$3,318
Suite
$4,181
From
US$2,299
Save 86
Per Person
View Trip
11 Day The Eternal Aegean with Ponant
Cruise
 (2)

11 Days (10 Nights) Valletta to Istanbul
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 May 2026
Visit: Malta, Sicily, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$9,970
Suite
-
From
US$9,970
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Messina to Messina
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Apr 2026 to Oct 2027
Visit: Sicily, Malta, Spain, France, Italy
Bonus Onboard Credit
Exclusive Savings
Inside
$1,166
Oceanview
$1,363
Balcony
$1,486
Suite
$2,320
From
US$1,166
Save 55
Per Person
View Trip
15 Day Sunlight & Stone with Regent Seven Seas
Cruise

15 Days (14 Nights) Venice to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 16 September 2027
Visit: Italy, Croatia, Greece, Turkey, Sicily
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,754
Suite
$13,901
From
US$13,754
Save 21,244
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Livorno to Livorno
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Virtuosa
Departures: May 2026 to Nov 2027
Visit: Italy, France, Spain, Tunisia, Sicily
Bonus Onboard Credit
Inside
$987
Oceanview
$1,156
Balcony
$1,307
Suite
$2,176
From
US$987
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC World Asia, MSC World Europa
Departures: Apr 2026 to Oct 2027
Visit: France, Italy, Sicily, Malta, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$720
Oceanview
$850
Balcony
$980
Suite
$1,770
From
US$720
Save 51
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Naples to Naples
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Apr 2026 to Oct 2027
Visit: Italy, Sicily, Malta, Spain, France
Bonus Onboard Credit
Exclusive Savings
Inside
$1,119
Oceanview
$1,336
Balcony
$1,536
Suite
$2,237
From
US$1,119
Save 55
Per Person
View Trip
12 Day Best Of Italy, France & Spain with Celebrity Cruises
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 24 May 2027
Visit: Spain, Corsica, France, Italy, Sicily
Exclusive Savings
Inside
$2,079
Oceanview
$2,235
Balcony
$2,456
Suite
$7,023
From
US$2,079
Save 1,198
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Santos to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy, Sicily
Bonus Onboard Credit
Inside
$1,501
Oceanview
$1,711
Balcony
$2,230
Suite
-
From
US$1,501
Per Person
View Trip
13 Day Fusina (Venice) to Nice with Silversea
Cruise

13 Days (12 Nights) Venice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 24 June 2027
Visit: Italy, Croatia, Malta, Sicily, France
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$6,930
Balcony
$8,370
Suite
$13,930
From
US$6,930
Save 770
Per Person
View Trip
8 Day Mount Etna To Lake Bled with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 29 July 2027
Visit: Italy, Sicily, Greece, Croatia, Slovenia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,099
Oceanview
$2,299
Balcony
$3,611
Suite
$5,066
From
US$2,099
Save 2,099
Per Person
View Trip
12 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (1)

12 Days (11 Nights) Athens to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 25 September 2026
Visit: Greece, Turkey, Sicily, Malta, Italy
Princess Standard
Inside
$3,109
Oceanview
-
Balcony
$3,075
Suite
$3,139
From
US$3,075
Per Person
View Trip
9 Day Mediterranean Islands with Seabourn
Cruise

9 Days (8 Nights) Rome to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,678
Suite
$9,843
From
US$6,678
Save 121
Per Person
View Trip
15 Day Mediterranean with Total Solar Eclipse with Princess
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 24 July 2027
Visit: Italy, France, Spain, Gibraltar, Sicily
Princess Standard
Exclusive Savings
Inside
$6,597
Oceanview
-
Balcony
$8,393
Suite
$9,439
From
US$6,597
Save 122
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Tunis to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 15 October 2026
Visit: Tunisia, Sicily, Italy, France, Spain
Inside
$529
Oceanview
-
Balcony
-
Suite
-
From
US$529
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy, France
Inside
$3,199
Oceanview
$2,849
Balcony
$4,979
Suite
-
From
US$2,849
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Feb 2026 to Mar 2028
Visit: Spain, France, Italy, Sicily, Malta
Bonus Onboard Credit
Exclusive Savings
Inside
$816
Oceanview
$937
Balcony
$1,076
Suite
$1,796
From
US$816
Save 52
Per Person
View Trip
15 Day Adriatic And Malta with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 30 July 2027
Visit: Italy, Malta, Croatia, Greece, Sicily
Inside
$2,879
Oceanview
$3,279
Balcony
$3,729
Suite
$8,123
From
US$2,879
Per Person
View Trip
8 Day Mediterranean with Greece & Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Oct 2026 to Oct 2026
Visit: Greece, Montenegro, Sicily, Italy, Spain
Princess Standard
Sanctuary Collection
Inside
$1,079
Oceanview
$1,359
Balcony
$1,504
Suite
$1,909
From
US$1,079
Per Person
View Trip
8 Day Amalfi Coast, Africa & Iberia with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Libra (+4 more), Viking Saturn, Viking Star, Viking Vela, Viking Vesta
Departures: Dec 2026 to Jun 2028
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,999
Suite
$4,799
From
US$2,999
Save 300
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Jan 2028
Visit: Sicily, Malta, Spain, France, Italy
Bonus Onboard Credit
Inside
$791
Oceanview
$951
Balcony
$1,081
Suite
$1,601
From
US$791
Per Person
View Trip
8 Day Italy & Croatia Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Bologna to Rome
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 20 September 2027
Visit: Italy, Croatia, Montenegro, Greece, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,197
Oceanview
$1,477
Balcony
$1,839
Suite
$2,489
From
US$1,197
Save 592
Per Person
View Trip
Results: 181-210 of 357

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