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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 357 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. October is the most popular month to cruise to Sicily and we have over 2,318 departures available from twenty-four of the world's leading cruise lines.
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357 Cruises (2,318 Cruise Departures)
7 Day Valletta to Nice with Silversea
Cruise

7 Days (6 Nights) Valletta to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: May 2026 to Jun 2026
Visit: Malta, Sicily, Italy, Corsica, France
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$4,260
Balcony
$4,680
Suite
-
From
US$4,260
Save 2,840
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Messina to Messina
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Feb 2026 to Mar 2028
Visit: Sicily, Malta, Spain, France, Italy
Bonus Onboard Credit
Exclusive Savings
Inside
$826
Oceanview
$976
Balcony
$1,017
Suite
$1,845
From
US$826
Save 52
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Naples to Naples
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Feb 2026 to Mar 2028
Visit: Italy, Sicily, Tunisia, Spain, France
Bonus Onboard Credit
Drinks, WiFi & Onboard Credit
Exclusive Savings
Inside
$593
Oceanview
$951
Balcony
$762
Suite
$1,262
From
US$593
Save 61
Per Person
View Trip
13 Day Eastern Mediterranean Gems with Regent Seven Seas
Cruise

13 Days (12 Nights) Barcelona to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 21 May 2026
Visit: Spain, Sicily, Croatia, Montenegro, Greece
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,958
Suite
$13,546
From
US$12,958
Save 18,640
Per Person
View Trip
11 Day Italy, Greece & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: Jun 2026 to Oct 2026
Visit: Italy, Sicily, Croatia, Montenegro, Greece
Exclusive Savings
Inside
$2,323
Oceanview
$2,423
Balcony
$2,949
Suite
$7,410
From
US$2,323
Save 1,973
Per Person
View Trip
11 Day Best Of Greece with Regent Seven Seas
Cruise

11 Days (10 Nights) Athens to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 October 2027
Visit: Greece, Sicily, Tunisia, Malta, Turkey
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,765
Suite
$9,039
From
US$7,765
Save 14,033
Per Person
View Trip
8 Day Italy, Malta, Croatia & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 08 May 2027
Visit: Italy, Sicily, Malta, Croatia, Montenegro
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,093
Suite
$11,632
From
US$6,093
Save 111
Per Person
View Trip
15 Day Italy, the Adriatic & Greece with Viking Cruises
Cruise
 (1)

15 Days (14 Nights) Athens to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Jun 2026 to Aug 2028
Visit: Greece, Montenegro, Croatia, Italy, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,598
Suite
$10,998
From
US$7,598
Save 1,300
Per Person
View Trip
22 Day The Best of the Mediterranean with Princess
Cruise
 (1)

22 Days (21 Nights) Athens to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 16 October 2027
Visit: Greece, Sicily, Malta, Turkey, Italy
Princess Standard
Inside
$3,378
Oceanview
-
Balcony
$4,260
Suite
$4,661
From
US$3,378
Per Person
View Trip
12 Day Mediterranean with Greek Isles & Italy with Princess
Cruise
 (1)

12 Days (11 Nights) Istanbul to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 26 October 2027
Visit: Turkey, Greece, Malta, Sicily, Italy
Princess Standard
Inside
$1,960
Oceanview
$2,369
Balcony
$2,105
Suite
$2,340
From
US$1,960
Per Person
View Trip
8 Day Adriatic Reflections with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 April 2027
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,639
Oceanview
$3,076
Balcony
$3,464
Suite
$4,773
From
US$2,639
Save 2,759
Per Person
View Trip
8 Day Italy & France Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Bologna
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 21 June 2027
Visit: Spain, France, Corsica, Italy, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,113
Oceanview
$1,412
Balcony
$1,675
Suite
$2,625
From
US$1,113
Save 562
Per Person
View Trip
15 Day Villas & Venice with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 June 2027
Visit: Italy, Sicily, Croatia, Montenegro, Greece
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,922
Suite
$14,588
From
US$12,922
Save 20,376
Per Person
View Trip
15 Day Italy, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 May 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Inside
$2,489
Oceanview
$2,719
Balcony
$2,979
Suite
$6,184
From
US$2,489
Per Person
View Trip
15 Day Western Mediterranean with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 August 2026
Visit: Italy, Spain, France, Sardinia, Sicily
Inside
$2,959
Oceanview
$3,119
Balcony
$3,629
Suite
$7,153
From
US$2,959
Per Person
View Trip
22 Day The Best of the Mediterranean with Princess
Cruise
 (1)

22 Days (21 Nights) Athens to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 22 May 2027
Visit: Greece, Sicily, Malta, Turkey, Italy
Princess Standard
Inside
$2,510
Oceanview
$3,538
Balcony
$3,142
Suite
$3,853
From
US$2,510
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Feb 2026 to Mar 2028
Visit: France, Italy, Sicily, Malta, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$840
Oceanview
$724
Balcony
$834
Suite
$1,830
From
US$724
Save 52
Per Person
View Trip
11 Day Greece, Italy & Malta Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Oct 2026 to Nov 2026
Visit: Spain, Malta, Greece, Sicily, Italy
Exclusive Savings
Inside
$1,373
Oceanview
$1,474
Balcony
$1,573
Suite
$4,929
From
US$1,373
Save 880
Per Person
View Trip
11 Day The Birth Of Civilization with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 17 November 2027
Visit: Greece, Turkey, Sicily, Italy, Sardinia
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,840
Oceanview
$3,665
Balcony
$4,392
Suite
$6,332
From
US$2,840
Save 2,958
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 May 2026
Visit: Spain, France, Italy, Corsica, Sicily
Inside
$2,639
Oceanview
$2,969
Balcony
$3,779
Suite
$5,866
From
US$2,639
Per Person
View Trip
10 Day Eclipse The Ordinary with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 29 July 2027
Visit: Spain, Malta, Sicily, Italy, Sardinia
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,768
Suite
$10,454
From
US$9,768
Save 15,130
Per Person
View Trip
13 Day Greece, Italy & Malta Cruise with Celebrity Cruises
Cruise
 (2)

13 Days (12 Nights) Athens to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Infinity
Departure: 25 October 2027
Visit: Greece, Malta, Sicily, Italy, Spain
Exclusive Savings
Inside
$1,774
Oceanview
$1,974
Balcony
$2,674
Suite
$5,256
From
US$1,774
Save 973
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Mar 2026 to Mar 2028
Visit: Italy, Sicily, Tunisia, Spain, France
Bonus Onboard Credit
Inside
$709
Oceanview
$826
Balcony
$925
Suite
$1,535
From
US$709
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 08 November 2027
Visit: France, Italy, Sicily, Malta, Spain
Bonus Onboard Credit
Inside
$1,021
Oceanview
$1,181
Balcony
$1,311
Suite
$1,831
From
US$1,021
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Amalfi to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 03 November 2027
Visit: Italy, Sicily, Malta, Spain, France
Bonus Onboard Credit
Inside
$1,753
Oceanview
$1,959
Balcony
$2,192
Suite
$3,123
From
US$1,753
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Naples to Naples
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Virtuosa
Departures: May 2026 to Nov 2027
Visit: Italy, France, Spain, Tunisia, Sicily
Bonus Onboard Credit
Inside
$887
Oceanview
$1,040
Balcony
$1,200
Suite
$2,159
From
US$887
Per Person
View Trip
8 Day Italy & France Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 03 August 2026
Visit: Spain, France, Corsica, Italy, Sicily
Exclusive Savings
Inside
$1,301
Oceanview
$1,531
Balcony
$2,210
Suite
$3,676
From
US$1,301
Save 648
Per Person
View Trip
22 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise
 (1)

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 14 September 2026
Visit: Italy, France, Sicily, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$5,429
Suite
$9,503
From
US$5,429
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (3)

7 Days (6 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 22 February 2026
Visit: Italy, Sicily, Malta, Spain, France
Inside
-
Oceanview
-
Balcony
$770
Suite
-
From
US$770
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departures: Jul 2027 to Aug 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
Exclusive Savings
Inside
$2,296
Oceanview
$2,791
Balcony
$3,392
Suite
$4,061
From
US$2,296
Save 65
Per Person
View Trip
Results: 241-270 of 357

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