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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 336 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. September is the most popular month to cruise to Sicily and we have over 2,407 departures available from twenty of the world's leading cruise lines.
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336 Cruises (2,407 Cruise Departures)
18 Day Discover the Charm of the Greek Isles & the Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

18 Days (17 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 10 October 2026
Countries Visited: Greece, Turkey, Sicily, Malta (+1 more), Italy
2 for 1 Fares2 for 1 Fare + Fly Free Economy
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,810
Save (per person) 19,370
From (per person) 18,810
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Seaside
Departures: Jun 2025 to Oct 2027
Countries Visited: Sicily, Italy, France, Spain (+1 more), Tunisia
Escape To Sea
INSIDE
$961
OCEANVIEW
$1,101
BALCONY
$1,251
SUITE
$1,853
From (per person) 961
View Trip
8 Day Italy & France Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Barcelona to Bologna
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departures: May 2026 to Sep 2026
Countries Visited: Spain, France, Corsica, Italy (+1 more), Sicily
Latest OfferExclusive Solo Offer
INSIDE
$1,021
OCEANVIEW
$1,267
BALCONY
$1,429
SUITE
$2,369
Save (per person) 25
From (per person) 1,516
View Trip
9 Day Mediterranean with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Trieste to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 29 October 2025
Countries Visited: Italy, Croatia, Greece, Malta (+1 more), Sicily
One Way Cruise Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$1,139
SUITE
-
From (per person) 1,139
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Nov 2025 to Apr 2027
Countries Visited: France, Italy, Sicily, Malta (+1 more), Spain
Escape To Sea
INSIDE
$670
OCEANVIEW
$778
BALCONY
$859
SUITE
$1,579
From (per person) 670
View Trip
15 Day An Extended Journey Of The Med’s Summer Harbours with Explora Journeys
Cruise
 (1)

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 August 2025
Countries Visited: Spain, France, Italy, Sicily (+1 more), Tunisia
Explora Extended Journey SavingBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$10,170
SUITE
$12,195
From (per person) 10,170
View Trip
11 Day Adriatic Antiquities: Italy & Croatia with Holland America
Cruise
 (2)

11 Days (10 Nights) Rome to Trieste
Cruise Line: Holland America
Ship: Oosterdam
Departure: 11 September 2027
Countries Visited: Italy, Sicily, Greece, Montenegro (+1 more), Croatia
Exclusive Deal
INSIDE
$2,014
OCEANVIEW
$2,164
BALCONY
$2,874
SUITE
$4,164
From (per person) 2,014
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Nov 2025 to Apr 2027
Countries Visited: Spain, France, Italy, Sicily (+1 more), Tunisia
Mutiple Deals Available
INSIDE
$560
OCEANVIEW
$650
BALCONY
$664
SUITE
$1,240
From (per person) 560
View Trip
8 Day A Journey Through Mediterranean Beauty, Artistic Spirit & Eternal Charms with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Jul 2026 to Sep 2026
Countries Visited: Spain, Tunisia, Malta, Sicily (+1 more), Italy
Best Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$4,920
SUITE
$5,680
From (per person) 4,920
View Trip
9 Day From the Adriatic Coast to Malta with Ponant
Cruise
 (1)

9 Days (8 Nights) Venice to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 05 August 2025
Countries Visited: Italy, Croatia, Montenegro, Sicily (+1 more), Malta
INSIDE
-
OCEANVIEW
-
BALCONY
$6,220
SUITE
$11,550
From (per person) 6,220
View Trip
9 Day From Malta to the Adriatic Coast with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 13 August 2025
Countries Visited: Malta, Sicily, Montenegro, Croatia (+1 more), Italy
INSIDE
-
OCEANVIEW
-
BALCONY
$6,840
SUITE
$11,550
From (per person) 6,840
View Trip
11 Day Mediterranean & Egypt Cruise: Alexandria, Heraklion & Rome with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 December 2026
Countries Visited: Greece, Egypt, Malta, Sicily (+1 more), Italy
INSIDE
$2,569
OCEANVIEW
$2,999
BALCONY
$3,799
SUITE
$5,799
From (per person) 2,569
View Trip
9 Day Splendours of Sicily, Italy and the French Riviera with Scenic
New ReleaseCruise

9 Days (8 Nights) Valletta to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 13 May 2027
Countries Visited: Malta, Sicily, Italy, Corsica (+2 more), France, Monaco
2 for 1 Fares + Fly Free Premium Economy2 for 1 Fares + Fly Free Business Class
INSIDE
-
OCEANVIEW
-
BALCONY
$11,165
SUITE
$17,265
Save (per person) 12,425
From (per person) 11,165
View Trip
8 Day The Adriatic & Italy with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 25 June 2026
Countries Visited: Italy, Croatia, Albania, Greece (+1 more), Sicily
Fleetwide SaleExclusive Deal
INSIDE
$2,299
OCEANVIEW
$2,549
BALCONY
$3,999
SUITE
$5,399
Save (per person) 2,299
From (per person) 2,299
View Trip
15 Day An Extended Journey To The Jewels Of Italy, Spain And France with Explora Journeys
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Jul 2025
Countries Visited: Italy, Sicily, Sardinia, Spain (+1 more), France
Explora Extended Journey SavingBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$8,755
SUITE
$12,745
From (per person) 8,755
View Trip
15 Day An Extended Journey From White Isle Bliss To Soulful Souks with Explora Journeys
Cruise
 (1)

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Jul 2025
Countries Visited: Spain, France, Italy, Sicily (+1 more), Tunisia
Explora Extended Journey SavingBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$9,785
SUITE
$12,110
From (per person) 9,785
View Trip
19 Day Italy Intensive Cruise: Taranto, Amalfi & Sorrento with Azamara Cruises
Cruise
 (3)

19 Days (18 Nights) Venice to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 May 2027
Countries Visited: Italy, Montenegro, Sicily, France (+1 more), Spain
INSIDE
$4,809
OCEANVIEW
$5,539
BALCONY
$7,059
SUITE
$10,339
From (per person) 4,809
View Trip
18 Day Adriatic Splendor: Amalfi Coast With History Channel with Holland America
Cruise
 (2)

18 Days (17 Nights) Athens to Trieste
Cruise Line: Holland America
Ship: Oosterdam
Departure: 04 September 2027
Countries Visited: Greece, Montenegro, Sicily, Italy (+1 more), Croatia
Exclusive Deal
INSIDE
$3,169
OCEANVIEW
$3,499
BALCONY
$4,419
SUITE
$6,679
From (per person) 3,169
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Seaside
Departures: Jun 2025 to Oct 2027
Countries Visited: France, Spain, Tunisia, Sicily (+1 more), Italy
Escape To Sea
INSIDE
$961
OCEANVIEW
$1,101
BALCONY
$1,251
SUITE
$1,878
From (per person) 961
View Trip
8 Day Adriatic Reflections with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 April 2027
Countries Visited: Italy, Sicily, Greece, Montenegro (+1 more), Croatia
Exclusive Deal
INSIDE
$2,599
OCEANVIEW
$3,099
BALCONY
$3,499
SUITE
$4,899
Save (per person) 2,599
From (per person) 2,599
View Trip
22 Day The Best of the Mediterranean with Princess
Cruise
 (1)

22 Days (21 Nights) Athens to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 22 May 2027
Countries Visited: Greece, Sicily, Malta, Turkey (+1 more), Italy
Summer Swing Sale
INSIDE
$3,350
OCEANVIEW
$4,049
BALCONY
$3,809
SUITE
$6,000
From (per person) 3,350
View Trip
11 Day Islands of the Mediterranean: Spain to Malta with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 25 April 2026
Countries Visited: Spain, Corsica, Sardinia, Sicily (+1 more), Malta
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$7,916
BALCONY
-
SUITE
$10,836
Save (per person) 8,074
From (per person) 7,916
View Trip
11 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 02 August 2025
Countries Visited: Italy, Greece, Malta, Sicily (+1 more), France
INSIDE
$1,512
OCEANVIEW
-
BALCONY
$2,002
SUITE
$2,092
From (per person) 1,512
View Trip
8 Day Adriatic & Ionian Artistry with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 12 May 2026
Countries Visited: Italy, Sicily, Greece, Albania (+1 more), Croatia
Fleetwide SaleExclusive Deal
INSIDE
$1,980
OCEANVIEW
$2,160
BALCONY
$3,240
SUITE
$4,500
Save (per person) 2,418
From (per person) 1,980
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Naples
Cruise Line: MSC Cruises
Ship: MSC World Asia
Departure: 12 April 2027
Countries Visited: Italy, Sicily, Malta, Spain (+1 more), France
Escape To Sea
INSIDE
$1,057
OCEANVIEW
$1,207
BALCONY
$1,277
SUITE
$1,967
From (per person) 1,057
View Trip
15 Day An Extended Journey To Modernist Masterpieces And Sunny Shores with Explora Journeys
Cruise
 (1)

15 Days (14 Nights) Rome to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 15 September 2025
Countries Visited: Italy, Sicily, Sardinia, Spain (+1 more), France
Explora Extended Journey SavingBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,105
From (per person) 14,105
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2027 to Oct 2027
Countries Visited: Spain, France, Italy, Sicily (+1 more), Malta
Escape To Sea
INSIDE
$1,006
OCEANVIEW
$1,146
BALCONY
$1,276
SUITE
$1,786
From (per person) 1,006
View Trip
8 Day 4th Opera Festival at Sea with Ponant
Cruise

8 Days (7 Nights) Venice to Valletta
Cruise Line: Ponant
Ship: L'Austral
Departure: 26 September 2025
Countries Visited: Italy, Croatia, Montenegro, Sicily (+1 more), Malta
INSIDE
-
OCEANVIEW
-
BALCONY
$8,140
SUITE
$16,980
From (per person) 8,140
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Nov 2025 to Apr 2027
Countries Visited: Italy, Sicily, Tunisia, Spain (+1 more), France
Escape To Sea
INSIDE
$576
OCEANVIEW
$776
BALCONY
$775
SUITE
$1,255
From (per person) 576
View Trip
12 Day Venice to Rome with Silversea
Cruise

12 Days (11 Nights) Venice to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 06 May 2026
Countries Visited: Italy, Croatia, Montenegro, Malta (+1 more), Sicily
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$9,600
BALCONY
$11,400
SUITE
$17,700
From (per person) 9,600
View Trip
Results: 241-270 of 336

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