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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 404 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. October is the most popular month to cruise to Sicily and we have over 2,304 departures available from twenty-four of the world's leading cruise lines.
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404 Cruises (2,304 Cruise Departures)
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 02 May 2027
Visit: Spain, Malta, Tunisia, Sicily, Italy
Inside
$1,179
Oceanview
$1,629
Balcony
$1,679
Suite
$1,849
From
US$1,179
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Jan 2028
Visit: Spain, France, Italy, Sicily, Malta
Inside
$836
Oceanview
$996
Balcony
$1,126
Suite
$1,646
From
US$836
Per Person
View Trip
15 Day A Holiday To Remember with Oceania Cruises
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 20 December 2027
Visit: Spain, Morocco, Tunisia, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,199
Suite
$8,499
From
US$6,199
Save 6,199
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 22 July 2026
Visit: Italy, Sicily, Malta, Greece, Turkey
Inside
$2,289
Oceanview
$2,449
Balcony
$2,869
Suite
$3,889
From
US$2,289
Per Person
View Trip
15 Day Italy, the Adriatic & Greece with Viking Cruises
Cruise
 (5)

15 Days (14 Nights) Athens to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Jul 2026 to Aug 2028
Visit: Greece, Montenegro, Croatia, Italy, Sicily
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,398
Suite
$10,798
From
US$7,398
Save 2,100
Per Person
View Trip
8 Day The Adriatic & Italy with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 25 June 2026
Visit: Italy, Croatia, Albania, Greece, Sicily
Your World Inclusions
Exclusive Savings
Inside
$1,875
Oceanview
$2,025
Balcony
$3,412
Suite
$4,125
From
US$1,875
Save 3,123
Per Person
View Trip
8 Day A Journey Through Mediterranean Beauty, Artistic Spirit & Eternal Charms with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Aug 2026 to Sep 2026
Visit: Spain, Tunisia, Malta, Sicily, Italy
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$5,000
From
US$5,000
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 November 2027
Visit: Spain, France, Italy, Sicily, Malta
Inside
$1,066
Oceanview
$1,226
Balcony
$1,356
Suite
$1,876
From
US$1,066
Per Person
View Trip
21 Day Barcelona to Rome with Silversea
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 September 2026
Visit: Spain, France, Monaco, Corsica, Italy, Sicily
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$12,200
Suite
$18,400
From
US$12,200
Per Person
View Trip
8 Day Italy & France Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Barcelona to Bologna
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departures: May 2026 to Sep 2026
Visit: Spain, France, Corsica, Italy, Sicily
Exclusive Savings
Inside
$951
Oceanview
$1,051
Balcony
$1,263
Suite
$1,999
From
US$951
Save 637
Per Person
View Trip
10 Day Italian Shores and Isle of Beauty with Ponant
Cruise
 (2)

10 Days (9 Nights) Valletta to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 June 2027
Visit: Malta, Sicily, Italy, Corsica, France
Inside
-
Oceanview
$7,090
Balcony
$7,470
Suite
$13,900
From
US$7,090
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Apr 2026 to Mar 2028
Visit: Italy, Sicily, Malta, Spain, France
Inside
$766
Oceanview
$966
Balcony
$1,086
Suite
$1,826
From
US$766
Per Person
View Trip
9 Day Wandering the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Athens to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 31 July 2027
Visit: Greece, Sicily, Italy, Corsica, France
Inside
-
Oceanview
-
Balcony
$6,120
Suite
$11,340
From
US$6,120
Per Person
View Trip
11 Day Isle of Beauty, Italian Shores & Malta with Ponant
Cruise

11 Days (10 Nights) Nice to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 19 August 2026
Visit: France, Corsica, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$8,950
Suite
$16,710
From
US$8,950
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Apr 2026 to Mar 2028
Visit: France, Italy, Sicily, Tunisia, Spain
Inside
$580
Oceanview
$930
Balcony
$1,030
Suite
$1,770
From
US$580
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Naples to Rome
Cruise Line: MSC Cruises
Ship: MSC World Asia
Departure: 01 November 2027
Visit: Italy, Sicily, Malta, Spain, France
Inside
$1,349
Oceanview
$1,549
Balcony
$1,669
Suite
$2,399
From
US$1,349
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Amalfi to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Jan 2028
Visit: Italy, Sicily, Malta, Spain, France
Inside
$791
Oceanview
$951
Balcony
$1,081
Suite
$1,601
From
US$791
Per Person
View Trip
19 Day Italy Intensive Cruise: Taranto, Amalfi & Sorrento with Azamara Cruises
Cruise
 (8)

19 Days (18 Nights) Venice to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 May 2027
Visit: Italy, Montenegro, Sicily, France, Spain
Azamara Always Included
Inside
$5,179
Oceanview
$5,959
Balcony
-
Suite
$11,059
From
US$5,179
Per Person
View Trip
12 Day Venice to Rome with Silversea
Cruise

12 Days (11 Nights) Venice to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 06 May 2026
Visit: Italy, Croatia, Montenegro, Malta, Sicily
All-Inclusive Fare
Inside
-
Oceanview
$8,800
Balcony
$11,600
Suite
-
From
US$8,800
Per Person
View Trip
15 Day Solar Eclipse & Astronomical Discovery with Holland America
Cruise
 (3)

15 Days (14 Nights) Athens to Athens
Cruise Line: Holland America
Ship: Oosterdam
Departure: 31 July 2027
Visit: Greece, Tunisia, Malta, Sardinia, Sicily
Book Early & Have It All Fare Option
Inside
$4,414
Oceanview
$4,654
Balcony
$7,479
Suite
$12,629
From
US$4,414
Per Person
View Trip
10 Day Alluring Ancient Ruins with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 15 May 2027
Visit: Turkey, Greece, Sicily, Italy, Sardinia
Your World Inclusions
Exclusive Savings
Inside
$2,430
Oceanview
$2,655
Balcony
$4,499
Suite
$6,399
From
US$2,430
Save 2,968
Per Person
View Trip
8 Day Adriatic & Greece From Bologna To Rome with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Bologna to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 16 August 2026
Visit: Italy, Croatia, Montenegro, Greece, Sicily
Inside
$949
Oceanview
$1,009
Balcony
$1,479
Suite
$1,579
From
US$949
Per Person
View Trip
8 Day Exploring Montenegro, Malta & Sicily with Seabourn
Cruise

8 Days (7 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 23 September 2028
Visit: Croatia, Montenegro, Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$5,219
Suite
$8,369
From
US$5,219
Per Person
View Trip
8 Day Pompeii, Sicily, Malta & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Monte Carlo to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 17 June 2028
Visit: Monaco, Italy, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$5,219
Suite
$8,369
From
US$5,219
Per Person
View Trip
11 Day Italy, Montenegro & Croatia Cruise: Rome, Kotor & Dubrovnik with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 31 October 2027
Visit: Spain, Italy, Sicily, Montenegro, Croatia
Azamara Always Included
Inside
$2,809
Oceanview
$3,419
Balcony
$4,219
Suite
$6,149
From
US$2,809
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departures: Jul 2027 to Aug 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
Inside
$2,359
Oceanview
$2,839
Balcony
$3,229
Suite
$4,179
From
US$2,359
Per Person
View Trip
15 Day Mediterranean & Italian Sojourn with Viking Cruises
Cruise
 (5)

15 Days (14 Nights) Venice to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Lyra (+8 more), Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: Jul 2026 to Sep 2028
Visit: Italy, Croatia, Sicily, Monaco, France, Spain
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,798
Suite
$8,998
From
US$6,798
Save 2,200
Per Person
View Trip
8 Day Mount Etna To Lake Bled with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 29 July 2027
Visit: Italy, Sicily, Greece, Croatia, Slovenia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,099
Oceanview
$2,399
Balcony
$3,699
Suite
$5,199
From
US$2,099
Save 2,099
Per Person
View Trip
11 Day Ancient Civilizations with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 09 February 2028
Visit: Italy, Sicily, Malta, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,199
Suite
$5,699
From
US$3,199
Save 3,199
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Virtuosa
Departures: May 2026 to Nov 2027
Visit: Spain, Tunisia, Sicily, Italy, France
Inside
$966
Oceanview
$1,106
Balcony
$1,286
Suite
$2,226
From
US$966
Per Person
View Trip
Results: 301-330 of 404

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