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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 384 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bologna and more. October is the most popular month to cruise to Sicily and we have over 2,193 departures available from twenty-four of the world's leading cruise lines.
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384 Cruises (2,193 Cruise Departures)
27 Day Treasures of Italy, Sicily and Malta with Adriatic Cruise with Travelmarvel
New ReleaseTour + Cruise

27 Days Dubrovnik to Valletta
Operated By: Travelmarvel
Ship: MV Princess Eleganza
Departures: Jun 2027 to Oct 2027
Visit: Croatia, Slovenia, Italy, Sicily, Malta
Inside
-
Oceanview
$16,245
Balcony
-
Suite
-
From
US$16,245
Per Person
View Trip
8 Day Barcelona to Rome with Silversea
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 01 November 2026
Visit: Spain, Sardinia, Tunisia, Sicily, Italy
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$6,400
Balcony
$6,800
Suite
$11,600
From
US$6,400
Per Person
View Trip
11 Day Breathtaking Greek Isles with Regent Seven Seas
Cruise

11 Days (10 Nights) Bologna to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 05 July 2027
Visit: Italy, Greece, Sicily, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,399
Suite
$12,099
From
US$11,399
Save 11,399
Per Person
View Trip
8 Day Barcelona to Rome with Silversea
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 07 September 2026
Visit: Spain, Sardinia, Tunisia, Sicily, Italy
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$5,250
Balcony
$5,950
Suite
$10,800
From
US$5,250
Per Person
View Trip
11 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 04 June 2027
Visit: Italy, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
$2,222
Oceanview
$2,318
Balcony
$2,788
Suite
$7,499
From
US$2,222
Save 1,284
Per Person
View Trip
11 Day Italy, Greece & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 28 August 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Exclusive Savings
Inside
$1,748
Oceanview
$1,963
Balcony
$2,274
Suite
$6,364
From
US$1,748
Save 1,012
Per Person
View Trip
10 Day From the Iberian Shores to the Italian Coast with Ponant
Cruise

10 Days (9 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 04 April 2027
Visit: Spain, Sicily, Italy, Malta
Inside
-
Oceanview
-
Balcony
$7,320
Suite
$13,610
From
US$7,320
Per Person
View Trip
17 Day An Extended Journey Of Island Chic & Riviera Glamour with Explora Journeys
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 05 October 2026
Visit: Italy, Monaco, France, Spain, Sicily
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$13,455
From
US$13,455
Per Person
View Trip
12 Day Greek Isles, Turkey & The Pyramids with Scenic
New ReleaseCruise

12 Days (11 Nights) Athens to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 25 June 2027
Visit: Greece, Turkey, Egypt, Sicily, Malta
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,006
Suite
$39,519
From
US$16,006
Save 2,354
Per Person
View Trip
9 Day Peaceful Islands and Ancient Treasures of the Mediterranean with Ponant
Cruise

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 14 June 2027
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$7,300
Suite
$13,630
From
US$7,300
Per Person
View Trip
11 Day Mediterranean Delights with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Valletta to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 20 July 2026
Visit: Malta, Sicily, Tunisia
Inside
-
Oceanview
-
Balcony
-
Suite
$11,495
From
US$11,495
Per Person
View Trip
8 Day Ancient Cities of the Mediterranean with Ponant
Cruise

8 Days (7 Nights) Athens to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 22 October 2026
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$6,590
Suite
$12,350
From
US$6,590
Per Person
View Trip
11 Day A Journey through Mediterranean Wonders & Ancient Echoes with Explora Journeys
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 March 2027
Visit: Spain, Italy, Malta, Tunisia, Sicily
Inside
-
Oceanview
-
Balcony
-
Suite
$5,495
From
US$5,495
Per Person
View Trip
11 Day Fusina (Venice) to Nice with Silversea
Cruise

11 Days (10 Nights) Venice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 07 May 2027
Visit: Italy, Croatia, Sicily, Malta, France
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$8,100
Balcony
$9,400
Suite
$14,300
From
US$8,100
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC World Asia
Departures: Dec 2026 to Mar 2028
Visit: Spain, France, Italy, Sicily, Malta
Inside
$746
Oceanview
$941
Balcony
$1,041
Suite
$1,761
From
US$746
Per Person
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Athens
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 31 May 2027
Visit: Spain, Sicily, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$1,201
Oceanview
$1,661
Balcony
$1,694
Suite
$2,268
From
US$1,201
Save 567
Per Person
View Trip
12 Day Fusina (Venice) to Civitavecchia (Rome) with Silversea
Cruise

12 Days (11 Nights) Venice to Rome
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 11 November 2027
Visit: Italy, Croatia, Sicily, Tunisia
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$7,700
Balcony
$8,500
Suite
$7,900
From
US$7,700
Per Person
View Trip
9 Day Mediterranean Islands with Seabourn
Cruise

9 Days (8 Nights) Rome to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily
Inside
-
Oceanview
-
Balcony
$7,819
Suite
$11,899
From
US$7,819
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 01 April 2027
Visit: France, Italy, Malta, Sicily, Corsica
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$8,500
Balcony
$10,000
Suite
$12,800
From
US$8,500
Save 1,500
Per Person
View Trip
8 Day Greece, Italy & Turkey Cruise with Celebrity Cruises
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 15 August 2026
Visit: Greece, Turkey, Sicily, Spain
Exclusive Savings
Inside
$1,107
Oceanview
$1,431
Balcony
$1,522
Suite
$5,382
From
US$1,107
Save 612
Per Person
View Trip
12 Day Italy Cruise: Hidden Treasures from Florence to Venice with Abercrombie & Kent
Tour + Cruise

12 Days Florence to Venice
Operated By: Abercrombie & Kent
Departure: 12 September 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Italy, Corsica, Sardinia, Sicily
Inside
-
Oceanview
-
Balcony
$17,995
Suite
$26,495
From
US$15,995
Per Person
View Trip
11 Day French Riviera & Amalfi Coast to Malta with Scenic
New ReleaseCruise

11 Days (10 Nights) Nice to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 May 2028
Visit: Malta, Sicily, Italy, Corsica, Monaco, France
Inside
-
Oceanview
-
Balcony
$13,395
Suite
$21,595
From
US$13,395
Per Person
View Trip
8 Day Pompeii, Sicily, Malta & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Monte Carlo to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 14 October 2028
Visit: Monaco, Italy, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$5,219
Suite
$8,369
From
US$5,219
Per Person
View Trip
10 Day Ancient Shores of the Mediterranean with Ponant
Cruise

10 Days (9 Nights) Valletta to Malaga
Cruise Line: Ponant
Ships: Le Bougainville, Le Champlain (+2 more), Le Dumont d’Urville, Le Laperouse
Departures: Oct 2026 to Nov 2027
Visit: Malta, Sicily, Tunisia, Algeria, Spain
Inside
-
Oceanview
-
Balcony
$7,760
Suite
$14,470
From
US$7,760
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Santos to Palermo
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily
Inside
$1,739
Oceanview
$2,049
Balcony
-
Suite
-
From
US$1,739
Per Person
View Trip
8 Day Malta, Italy & Spain with Seabourn
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 October 2027
Visit: Greece, Malta, Sicily, Sardinia, Spain
Inside
-
Oceanview
-
Balcony
$5,524
Suite
$8,499
From
US$5,524
Per Person
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departures: Oct 2026 to Oct 2026
Visit: Italy, Sicily, Greece
Exclusive Savings
Inside
$1,198
Oceanview
$1,791
Balcony
$2,706
Suite
$3,410
From
US$1,198
Save 821
Per Person
View Trip
8 Day Adriatic & Greece From Bologna To Rome with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Bologna to Rome
Cruise Line: Norwegian Cruise Line
Ships: Norwegian Gem, Norwegian Sun
Departures: Jun 2026 to Aug 2027
Visit: Italy, Croatia, Montenegro, Greece, Sicily
Inside
$829
Oceanview
$959
Balcony
$1,549
Suite
$1,659
From
US$829
Per Person
View Trip
8 Day Exploring Italy, Malta & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$4,949
Suite
$8,999
From
US$4,949
Per Person
View Trip
11 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 25 June 2027
Visit: Italy, Sicily, Croatia, Montenegro
Exclusive Savings
Inside
$2,057
Oceanview
$2,074
Balcony
$2,845
Suite
$6,183
From
US$2,057
Save 1,190
Per Person
View Trip
Results: 271-300 of 384

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