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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 357 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. October is the most popular month to cruise to Sicily and we have over 2,318 departures available from twenty-four of the world's leading cruise lines.
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357 Cruises (2,318 Cruise Departures)
9 Day Wandering the Mediterranean with Ponant
Cruise
 (1)

9 Days (8 Nights) Athens to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 31 July 2027
Visit: Greece, Sicily, Italy, Corsica, France
Inside
-
Oceanview
-
Balcony
$6,120
Suite
$11,340
From
US$6,120
Per Person
View Trip
11 Day Adriatic Antiquities: Italy & Croatia with Holland America
Cruise
 (2)

11 Days (10 Nights) Rome to Trieste
Cruise Line: Holland America
Ship: Oosterdam
Departure: 11 September 2027
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Book Early & Have It All Fare Option
Inside
$2,014
Oceanview
$2,164
Balcony
$2,874
Suite
$4,090
From
US$2,014
Per Person
View Trip
11 Day Greek Isles & Turkey Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 15 August 2026
Visit: Spain, Sicily, Greece, Turkey, Italy
Exclusive Savings
Inside
$1,860
Oceanview
$2,058
Balcony
$2,552
Suite
$4,914
From
US$1,860
Save 1,057
Per Person
View Trip
8 Day Italy & Croatia Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Bologna to Rome
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departures: Jun 2027 to Oct 2027
Visit: Italy, Croatia, Montenegro, Greece, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,127
Oceanview
$1,469
Balcony
$1,789
Suite
$2,489
From
US$1,127
Save 627
Per Person
View Trip
8 Day Adriatic & Ionian Artistry with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 12 May 2026
Visit: Italy, Sicily, Greece, Albania, Croatia
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$4,579
Balcony
-
Suite
-
From
US$4,579
Save 4,819
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Jan 2028
Visit: France, Italy, Sicily, Malta, Spain
Bonus Onboard Credit
Inside
$791
Oceanview
$951
Balcony
$1,081
Suite
$1,601
From
US$791
Per Person
View Trip
11 Day Italy, Montenegro & Croatia Cruise: Rome, Kotor & Dubrovnik with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 31 October 2027
Visit: Spain, Italy, Sicily, Montenegro, Croatia
Azamara Always Included
Exclusive Savings
Inside
$2,748
Oceanview
$3,340
Balcony
$4,116
Suite
$5,988
From
US$2,748
Save 61
Per Person
View Trip
11 Day 10th Annual Piano Festival at Sea with Ponant
Cruise

11 Days (10 Nights) Valletta to Antalya
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departures: Mar 2026 to Apr 2027
Visit: Malta, Sicily, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$7,650
Suite
$14,170
From
US$7,650
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Oct 2027
Visit: Malta, Spain, France, Italy, Sicily
Bonus Onboard Credit
Inside
$1,046
Oceanview
$1,186
Balcony
$1,326
Suite
$2,223
From
US$1,046
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Florence
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 20 April 2026
Visit: Italy, Sicily, Tunisia, Spain, France
Inside
-
Oceanview
-
Balcony
$989
Suite
$1,459
From
US$989
Per Person
View Trip
11 Day Icons of the Mediterranean with Viking Cruises
Cruise
 (5)

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Viking Cruises
Ship: Viking Sea
Departure: 22 September 2026
Visit: Spain, France, Italy, Sicily, Greece
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,999
Suite
$9,999
From
US$6,999
Save 500
Per Person
View Trip
11 Day Italy, France & Malta Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 10 October 2026
Visit: Spain, Malta, Sicily, Italy, France
Exclusive Savings
Inside
$1,674
Oceanview
$1,775
Balcony
$1,874
Suite
$6,951
From
US$1,674
Save 1,003
Per Person
View Trip
15 Day Mediterranean, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Inside
$2,399
Oceanview
$2,699
Balcony
$2,909
Suite
$5,867
From
US$2,399
Per Person
View Trip
10 Day Mediterranean: Athens to Rome with Virgin Voyages
Cruise
 (1)

10 Days (9 Nights) Athens to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 29 August 2027
Visit: Greece, Turkey, Malta, Sicily, Italy
With Love From the World
Inside
$2,069
Oceanview
$2,241
Balcony
$2,411
Suite
$6,075
From
US$2,069
Per Person
View Trip
15 Day Solar Eclipse & Astronomical Discovery with Holland America
Cruise
 (2)

15 Days (14 Nights) Athens to Athens
Cruise Line: Holland America
Ship: Oosterdam
Departure: 31 July 2027
Visit: Greece, Tunisia, Malta, Sardinia, Sicily
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,339
Oceanview
$4,574
Balcony
$7,343
Suite
-
From
US$4,339
Save 75
Per Person
View Trip
12 Day Best Of Italy & Greece Cruise with Royal Caribbean
Cruise
 (1)

12 Days (11 Nights) Barcelona to Athens
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 03 May 2027
Visit: Spain, Italy, Sicily, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$2,297
Oceanview
$2,738
Balcony
$4,676
Suite
$5,660
From
US$2,297
Save 1,033
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Jan 2028
Visit: Italy, Sicily, Malta, Spain, France
Bonus Onboard Credit
Inside
$839
Oceanview
$999
Balcony
$1,129
Suite
$1,649
From
US$839
Per Person
View Trip
14 Day Turkey, Egypt & Italy Cruise: Ephesus, Alexandria & Amalfi Coast with Azamara Cruises
Cruise
 (3)

14 Days (13 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 21 November 2027
Visit: Greece, Turkey, Egypt, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$3,368
Oceanview
$4,153
Balcony
$5,181
Suite
$7,509
From
US$3,368
Save 71
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 November 2027
Visit: Spain, France, Italy, Sicily, Malta
Bonus Onboard Credit
Inside
$1,066
Oceanview
$1,226
Balcony
$1,356
Suite
$1,876
From
US$1,066
Per Person
View Trip
8 Day Venetian Strongholds with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 June 2026
Visit: Italy, Slovenia, Croatia, Greece, Sicily
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,280
Oceanview
$2,375
Balcony
$3,528
Suite
$4,634
From
US$2,280
Save 2,518
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (3)

6 Days (5 Nights) Messina to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 03 November 2026
Visit: Sicily, Malta, Spain, France, Italy
Inside
$499
Oceanview
$629
Balcony
$829
Suite
-
From
US$499
Per Person
View Trip
13 Day Mediterranean: Rome to Athens with Virgin Voyages
Cruise
 (1)

13 Days (12 Nights) Rome to Athens
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 07 September 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
With Love From the World
Inside
$2,581
Oceanview
$2,868
Balcony
$3,108
Suite
$8,100
From
US$2,581
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Virtuosa
Departures: May 2026 to Nov 2027
Visit: Sicily, Italy, France, Spain, Tunisia
Bonus Onboard Credit
Drinks, WiFi & Onboard Credit
Exclusive Savings
Inside
$819
Oceanview
$989
Balcony
$1,149
Suite
$2,314
From
US$819
Save 72
Per Person
View Trip
15 Day Mediterranean & Italian Sojourn with Viking Cruises
Cruise
 (8)

15 Days (14 Nights) Barcelona to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Mar 2026 to Jul 2028
Visit: Spain, France, Monaco, Italy, Sicily, Croatia
Viking $999 Air Deal
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,398
Suite
$10,198
From
US$7,398
Save 1,400
Per Person
View Trip
8 Day Italy & France Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Barcelona to Bologna
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departures: May 2026 to Sep 2026
Visit: Spain, France, Corsica, Italy, Sicily
Exclusive Savings
Inside
$1,162
Oceanview
$1,322
Balcony
$1,714
Suite
$3,147
From
US$1,162
Save 708
Per Person
View Trip
8 Day The Adriatic & Italy with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Venice to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 25 June 2026
Visit: Italy, Croatia, Albania, Greece, Sicily
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$2,115
Oceanview
$2,295
Balcony
$3,603
Suite
$4,738
From
US$2,115
Save 2,583
Per Person
View Trip
18 Day Adriatic Splendor: Amalfi Coast With History Channel with Holland America
Cruise
 (2)

18 Days (17 Nights) Athens to Trieste
Cruise Line: Holland America
Ship: Oosterdam
Departure: 04 September 2027
Visit: Greece, Montenegro, Sicily, Italy, Croatia
Book Early & Have It All Fare Option
Inside
$3,169
Oceanview
$3,445
Balcony
$4,346
Suite
$6,561
From
US$3,169
Per Person
View Trip
11 Day Mediterranean Medley with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 02 July 2026
Visit: Italy, Sicily, Malta, Spain, France, Monaco
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$3,035
Oceanview
$3,297
Balcony
$5,043
Suite
$6,571
From
US$3,035
Save 3,863
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 17 October 2027
Visit: Spain, Tunisia, Malta, Sicily, Italy
Inside
$1,149
Oceanview
-
Balcony
$1,589
Suite
$1,857
From
US$1,149
Per Person
View Trip
12 Day Tales Of The Ancients with Oceania Cruises
Cruise
 (1)

12 Days (11 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 16 June 2027
Visit: Turkey, Greece, Malta, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,573
Oceanview
$3,718
Balcony
$5,707
Suite
$8,083
From
US$3,573
Save 3,725
Per Person
View Trip
Results: 271-300 of 357

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