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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 357 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. October is the most popular month to cruise to Sicily and we have over 2,318 departures available from twenty-four of the world's leading cruise lines.
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357 Cruises (2,318 Cruise Departures)
8 Day Mediterranean Wayfarer with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 06 June 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,871
Suite
$5,647
From
US$4,871
Save 5,127
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 04 November 2027
Visit: Sicily, Malta, Spain, France, Italy
Bonus Onboard Credit
Inside
$1,039
Oceanview
$1,199
Balcony
$1,329
Suite
$1,849
From
US$1,039
Per Person
View Trip
12 Day Mediterranean with Greek Isles & Italy with Princess
Cruise
 (1)

12 Days (11 Nights) Istanbul to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departures: Jun 2027 to Sep 2027
Visit: Turkey, Greece, Malta, Sicily, Italy
Princess Standard
Inside
$1,220
Oceanview
$1,849
Balcony
$1,601
Suite
$1,820
From
US$1,220
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Jan 2028
Visit: Spain, France, Italy, Sicily, Malta
Bonus Onboard Credit
Inside
$836
Oceanview
$996
Balcony
$1,126
Suite
$1,646
From
US$836
Per Person
View Trip
15 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia, Spain
Inside
$2,629
Oceanview
$2,929
Balcony
$3,579
Suite
$7,905
From
US$2,629
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Naples to Rome
Cruise Line: MSC Cruises
Ship: MSC World Asia
Departure: 01 November 2027
Visit: Italy, Sicily, Malta, Spain, France
Bonus Onboard Credit
Inside
$1,349
Oceanview
$1,549
Balcony
$1,669
Suite
$2,333
From
US$1,349
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Virtuosa
Departures: May 2026 to Nov 2027
Visit: Spain, Tunisia, Sicily, Italy, France
Bonus Onboard Credit
Inside
$836
Oceanview
$1,006
Balcony
$1,156
Suite
$2,165
From
US$836
Per Person
View Trip
12 Day Mediterranean with Greek Isles & Italy with Princess
Cruise
 (6)

12 Days (11 Nights) Istanbul to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Jul 2027 to Aug 2027
Visit: Turkey, Greece, Sicily, Italy, Spain
Princess Standard
Sanctuary Collection
Inside
$1,559
Oceanview
$1,959
Balcony
$1,970
Suite
$2,389
From
US$1,559
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Amalfi to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Jan 2028
Visit: Italy, Sicily, Malta, Spain, France
Bonus Onboard Credit
Inside
$791
Oceanview
$951
Balcony
$1,081
Suite
$1,601
From
US$791
Per Person
View Trip
11 Day Eastbound Adventure with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 18 October 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,031
Oceanview
$3,855
Balcony
$4,583
Suite
$6,523
From
US$3,031
Save 3,167
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Feb 2026 to Mar 2028
Visit: Italy, Sicily, Malta, Spain, France
Bonus Onboard Credit
Exclusive Savings
Inside
$622
Oceanview
$730
Balcony
$970
Suite
$1,772
From
US$622
Save 52
Per Person
View Trip
9 Day Barcelona to Amalfi, Sicily & Greece with Virgin Voyages
Cruise
 (1)

9 Days (8 Nights) Barcelona to Athens
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 08 May 2027
Visit: Spain, Corsica, Italy, Sicily, Greece
With Love From the World
Inside
$1,989
Oceanview
$2,293
Balcony
$2,407
Suite
$5,400
From
US$1,989
Per Person
View Trip
18 Day Mediterranean & Egypt Cruise: Italy, Greece & Malta with Azamara Cruises
Cruise
 (8)

18 Days (17 Nights) Rome to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 December 2026
Visit: Italy, Sicily, Greece, Egypt, Malta
Azamara Always Included
Exclusive Savings
Inside
$3,825
Oceanview
$4,339
Balcony
$5,009
Suite
$8,035
From
US$3,825
Save 74
Per Person
View Trip
11 Day Italian & Aegean Idyll with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 01 May 2026
Visit: Italy, Sicily, Tunisia, Greece, Turkey
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$3,083
Oceanview
$3,389
Balcony
-
Suite
$13,316
From
US$3,083
Save 3,915
Per Person
View Trip
19 Day Italy Intensive Cruise: Taranto, Amalfi & Sorrento with Azamara Cruises
Cruise
 (8)

19 Days (18 Nights) Venice to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 May 2027
Visit: Italy, Montenegro, Sicily, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$5,074
Oceanview
$5,830
Balcony
-
Suite
$10,777
From
US$5,074
Save 105
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC World Asia, MSC World Europa
Departures: Apr 2026 to Oct 2027
Visit: Italy, Sicily, Malta, Spain, France
Bonus Onboard Credit
Exclusive Savings
Inside
$731
Oceanview
$851
Balcony
$981
Suite
$1,711
From
US$731
Save 50
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Naples
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Apr 2026 to Apr 2027
Visit: Italy, Sicily, Malta, Spain, France
Bonus Onboard Credit
Inside
$1,104
Oceanview
$1,264
Balcony
$1,364
Suite
$2,037
From
US$1,104
Per Person
View Trip
15 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (8)

15 Days (14 Nights) Barcelona to Athens
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Visit: Spain, France, Italy, Sicily, Greece
Azamara Always Included
Exclusive Savings
Inside
$2,969
Oceanview
$3,357
Balcony
$3,987
Suite
$6,344
From
US$2,969
Save 50
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Feb 2026 to Mar 2028
Visit: Italy, Sicily, Malta, Spain, France
Bonus Onboard Credit
Exclusive Savings
Inside
$702
Oceanview
$792
Balcony
$882
Suite
$1,604
From
US$702
Save 52
Per Person
View Trip
15 Day Mediterranean & Italian Sojourn with Viking Cruises
Cruise
 (1)

15 Days (14 Nights) Venice to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Lyra (+8 more), Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Vela, Viking Vesta
Departures: May 2026 to Sep 2028
Visit: Italy, Croatia, Sicily, Monaco, France, Spain
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,298
Suite
$9,898
From
US$7,298
Save 1,500
Per Person
View Trip
8 Day Ancient Sites & Cities with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 November 2026
Visit: Italy, Sicily, Malta, Greece, Turkey
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$1,827
Oceanview
$1,955
Balcony
$2,822
Suite
$3,894
From
US$1,827
Save 2,471
Per Person
View Trip
15 Day Mediterranean And Croatia with Cunard
Cruise
 (13)

15 Days (14 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 04 June 2027
Visit: Italy, Croatia, Sicily, Spain, Corsica
Inside
$2,359
Oceanview
$2,679
Balcony
$3,199
Suite
$6,648
From
US$2,359
Per Person
View Trip
9 Day Barcelona to Civitavecchia (Rome) with Silversea
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 21 May 2027
Visit: Spain, Sardinia, Sicily, Malta, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,810
Suite
$8,510
From
US$5,810
Save 2,490
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 02 May 2027
Visit: Spain, Malta, Tunisia, Sicily, Italy
Inside
$1,189
Oceanview
-
Balcony
$1,679
Suite
$1,828
From
US$1,189
Per Person
View Trip
10 Day Ancient Shores of the Mediterranean with Ponant
Cruise
 (2)

10 Days (9 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 05 May 2026
Visit: Spain, Algeria, Tunisia, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$8,560
Suite
$16,050
From
US$8,560
Per Person
View Trip
9 Day Splendours of Sicily, Italy and the French Riviera with Scenic
New ReleaseCruise

9 Days (8 Nights) Valletta to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 13 May 2027
Visit: Malta, Sicily, Italy, Corsica, France, Monaco
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,991
Suite
$14,453
From
US$9,991
Save 13,599
Per Person
View Trip
15 Day Slovenia, Croatia, Montenegro & Italy with Seabourn
Cruise

15 Days (14 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 04 September 2027
Visit: Croatia, Slovenia, Montenegro, Sicily, Italy
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,941
Suite
$21,020
From
US$10,941
Save 193
Per Person
View Trip
15 Day Italy, the Adriatic & Greece with Viking Cruises
Cruise
 (5)

15 Days (14 Nights) Rome to Athens
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Jul 2026 to Jul 2028
Visit: Italy, Sicily, Croatia, Montenegro, Greece
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,198
Suite
$9,998
From
US$7,198
Save 1,400
Per Person
View Trip
22 Day The Best of the Mediterranean with Princess
Cruise
 (1)

22 Days (21 Nights) Athens to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 04 September 2027
Visit: Greece, Sicily, Malta, Turkey, Italy
Princess Standard
Exclusive Savings
Inside
$4,442
Oceanview
$5,234
Balcony
$4,747
Suite
$6,039
From
US$4,442
Save 68
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

21 Days (20 Nights) Rio de Janeiro to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 April 2027
Visit: Brazil, Spain, France, Italy, Sicily
Bonus Onboard Credit
Inside
$1,429
Oceanview
$1,659
Balcony
$2,169
Suite
-
From
US$1,429
Per Person
View Trip
Results: 211-240 of 357

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