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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 384 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bologna and more. October is the most popular month to cruise to Sicily and we have over 2,193 departures available from twenty-four of the world's leading cruise lines.
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384 Cruises (2,193 Cruise Departures)
8 Day Croatia, Montenegro & Italy with Seabourn
Cruise

8 Days (7 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy
Inside
-
Oceanview
-
Balcony
$5,864
Suite
$10,199
From
US$5,864
Per Person
View Trip
8 Day A Journey Through Cultural Elegance & Timeless Discovery with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 14 August 2028
Visit: Spain, Tunisia, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$4,585
From
US$4,585
Per Person
View Trip
8 Day Fusina (Venice) to Valletta with Silversea
Cruise

8 Days (7 Nights) Venice to Valletta
Cruise Line: Silversea
Ship: Silver Muse
Departure: 07 October 2026
Visit: Italy, Slovenia, Croatia, Sicily, Malta
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$10,900
From
US$10,900
Save 2,500
Per Person
View Trip
9 Day Ancient Cities of the Mediterranean with Ponant
Cruise

9 Days (8 Nights) Athens to Valletta
Cruise Line: Ponant
Ships: Le Champlain, Le Dumont d’Urville
Departures: Nov 2026 to Oct 2027
Visit: Greece, Italy, Sicily, Malta
Inside
-
Oceanview
-
Balcony
$9,690
Suite
$13,370
From
US$9,690
Per Person
View Trip
11 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 17 September 2027
Visit: Italy, Sicily, Croatia, Montenegro
Exclusive Savings
Inside
$1,925
Oceanview
$2,210
Balcony
$2,624
Suite
$6,199
From
US$1,925
Save 1,111
Per Person
View Trip
11 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Bologna to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departures: May 2026 to Aug 2026
Visit: Italy, Croatia, Montenegro, Sicily
Exclusive Savings
Inside
$1,099
Oceanview
$1,219
Balcony
$1,930
Suite
$6,722
From
US$1,099
Save 1,087
Per Person
View Trip
8 Day Greece, Italy & Turkey Cruise with Celebrity Cruises
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 21 August 2027
Visit: Greece, Turkey, Sicily, Spain
Exclusive Savings
Inside
$1,600
Oceanview
$2,044
Balcony
$2,138
Suite
$6,503
From
US$1,600
Save 903
Per Person
View Trip
8 Day Under Sail from Sicily to the Riviera with Ponant
Cruise

8 Days (7 Nights) Palermo to Nice
Cruise Line: Ponant
Ship: Le Ponant
Departure: 24 August 2027
Visit: Sicily, Italy, France
Inside
-
Oceanview
$12,790
Balcony
$19,470
Suite
$40,250
From
US$12,790
Per Person
View Trip
15 Day Harbors Of Heritage with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 22 July 2027
Visit: Italy, Sicily, Montenegro, Croatia, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,199
Suite
$17,449
From
US$17,199
Save 17,199
Per Person
View Trip
8 Day Italy, Malta, Croatia & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 08 May 2027
Visit: Italy, Sicily, Malta, Croatia, Montenegro
Inside
-
Oceanview
-
Balcony
$6,204
Suite
$14,823
From
US$6,204
Per Person
View Trip
8 Day Stars Of The Mediterranean with Regent Seven Seas
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 04 July 2027
Visit: Greece, Malta, Sicily, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,099
Suite
$10,849
From
US$10,099
Save 10,099
Per Person
View Trip
10 Day Nice to Nice with Silversea
Cruise

10 Days (9 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 06 July 2027
Visit: France, Italy, Sicily, Malta
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$8,200
Balcony
$8,900
Suite
$11,800
From
US$8,200
Per Person
View Trip
15 Day A Holiday To Remember with Oceania Cruises
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 20 December 2027
Visit: Spain, Morocco, Tunisia, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,199
Suite
$8,499
From
US$6,199
Save 6,199
Per Person
View Trip
7 Day Valletta to Nice with Silversea
Cruise

7 Days (6 Nights) Valletta to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 13 June 2026
Visit: Malta, Sicily, Italy, Corsica, France
Last Minute Fare
Inside
-
Oceanview
$4,350
Balcony
$4,850
Suite
-
From
US$4,350
Per Person
View Trip
8 Day Valletta to Lisbon with Silversea
Cruise

8 Days (7 Nights) Valletta to Lisbon
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 October 2026
Visit: Malta, Sicily, Sardinia, Spain, Portugal
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
-
Suite
$11,700
From
US$11,700
Per Person
View Trip
8 Day Italy & Croatia Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Bologna to Rome
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departures: Jun 2027 to Oct 2027
Visit: Italy, Croatia, Montenegro, Greece, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,197
Oceanview
$1,576
Balcony
$1,819
Suite
$2,624
From
US$1,197
Save 648
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Naples to Rome
Cruise Line: MSC Cruises
Ship: MSC World Asia
Departure: 01 November 2027
Visit: Italy, Sicily, Malta, Spain, France
Inside
$1,349
Oceanview
$1,549
Balcony
$1,669
Suite
$2,399
From
US$1,349
Per Person
View Trip
8 Day Italy & France Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Bologna
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 02 August 2027
Visit: Spain, France, Italy, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,077
Oceanview
$1,427
Balcony
$1,669
Suite
$2,514
From
US$1,077
Save 541
Per Person
View Trip
15 Day Idyllic Days with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 09 September 2027
Visit: Italy, Sicily, Montenegro, Croatia, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$20,099
From
US$20,099
Save 20,099
Per Person
View Trip
15 Day Sunlight & Stone with Regent Seven Seas
Cruise

15 Days (14 Nights) Trieste to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 16 September 2027
Visit: Italy, Croatia, Greece, Turkey, Sicily
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$20,149
From
US$20,149
Save 20,149
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Venice to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departure: 02 November 2027
Visit: Italy, Sicily, Spain, Brazil
Inside
$1,309
Oceanview
$1,789
Balcony
$3,099
Suite
$3,859
From
US$1,309
Per Person
View Trip
11 Day Rome to Venice with Silversea
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 September 2026
Visit: Italy, Sicily, Montenegro, Croatia
All-Inclusive Fare
Inside
-
Oceanview
$9,900
Balcony
$10,400
Suite
$21,600
From
US$9,900
Per Person
View Trip
8 Day A Journey Of Historic Splendour & Stunning Landscapes with Explora Journeys
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2026
Visit: Monaco, Italy, Sicily, Malta, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,650
From
US$5,650
Per Person
View Trip
8 Day Heaven On The Med with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 22 July 2027
Visit: Italy, Sicily, Montenegro, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,399
Suite
$9,749
From
US$9,399
Save 9,399
Per Person
View Trip
9 Day Italy, France & Tunisia with Seabourn
Cruise

9 Days (8 Nights) Genoa to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 April 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily
Inside
-
Oceanview
-
Balcony
$6,119
Suite
$12,834
From
US$6,119
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Asia
Departures: Dec 2026 to Mar 2028
Visit: Italy, Sicily, Malta, Spain, France
Inside
$736
Oceanview
$911
Balcony
$1,031
Suite
$1,771
From
US$736
Per Person
View Trip
11 Day 10th Annual Piano Festival at Sea with Ponant
Cruise

11 Days (10 Nights) Valletta to Antalya
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 13 April 2027
Visit: Malta, Sicily, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$10,050
Suite
$17,040
From
US$10,050
Per Person
View Trip
11 Day Italian Celebration with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 May 2027
Visit: Spain, France, Monaco, Italy, Sicily, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,849
Suite
$15,199
From
US$13,849
Save 13,849
Per Person
View Trip
8 Day Croatia, Malta & Italy with Seabourn
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 02 October 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$7,054
Suite
$10,709
From
US$7,054
Per Person
View Trip
11 Day Civitavecchia (Rome) to Fusina (Venice) with Silversea
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 23 June 2026
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Last Minute Fare
All-Inclusive Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
$6,750
Balcony
$7,550
Suite
-
From
US$6,750
Per Person
View Trip
Results: 211-240 of 384

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