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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 241 unique cruise itineraries to Sicily, departing from Antalya, Athens, Barcelona, Florence, Genoa and more. October is the most popular month to cruise to Sicily and we have over 1,411 departures available from twenty of the world's leading cruise lines.
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29 Days
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241 Cruises (1,411 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Messina to Messina
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: May 2024 to Oct 2025
Countries Visited: Sicily, Malta, Spain, France (+1 more), Italy
Mutiple Deals Available
INSIDE
$1,801
OCEANVIEW
$2,069
BALCONY
$2,267
SUITE
$3,543
From 1,801
View Trip
11 Day Around Italy's Boot: Palermo with Holland America
Cruise
 (1)

11 Days (10 Nights) Venice to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 19 June 2025
Countries Visited: Italy, Croatia, Montenegro, Greece (+1 more), Sicily
Have It All Offer
INSIDE
$3,322
OCEANVIEW
$3,767
BALCONY
$4,559
SUITE
$6,094
From 3,322
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: May 2024 to Nov 2025
Countries Visited: France, Italy, Sicily, Malta (+1 more), Spain
Mutiple Deals Available
INSIDE
$1,801
OCEANVIEW
$2,069
BALCONY
$2,247
SUITE
$2,979
From 1,801
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Messina to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 08 April 2025
Countries Visited: Sicily, Malta, Spain, France (+1 more), Italy
Exclusive Deal
INSIDE
$853
OCEANVIEW
$1,041
BALCONY
$1,299
SUITE
-
From 853
View Trip
8 Day Malta & Aegean Jewels with Holland America
Cruise
 (1)

8 Days (7 Nights) Rome to Athens
Cruise Line: Holland America
Ship: Oosterdam
Departure: 01 September 2024
Countries Visited: Italy, Sicily, Malta, Greece (+1 more), Turkey
Have It All Offer
INSIDE
$1,984
OCEANVIEW
$2,182
BALCONY
$2,504
SUITE
$3,454
From 1,984
View Trip
12 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Rome to Rome
Ship: Norwegian Epic
Departures: Oct 2024 to Oct 2025
Countries Visited: Italy, Greece, Malta, Sicily (+1 more), France
Exclusive Solo Offer
INSIDE
$2,907
OCEANVIEW
-
BALCONY
$4,513
SUITE
$5,048
From 2,907
View Trip
18 Day Discover the Jewels of French & Italian Rivieras with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 12 October 2024
Countries Visited: France, Italy, Corsica, Sicily (+1 more), Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$21,508
Save 7,217
From 21,508
View Trip
11 Day Greece & Italy with Princess
Cruise

11 Days (10 Nights) Istanbul to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 19 July 2025
Countries Visited: Turkey, Greece, Montenegro, Sicily (+1 more), Italy
INSIDE
$2,749
OCEANVIEW
$3,294
BALCONY
$3,442
SUITE
$4,363
From 2,749
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 24 October 2024
Countries Visited: France, Spain, Italy, Sicily (+1 more), Tunisia
Early Booking Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$2,262
SUITE
$3,272
From 2,262
View Trip
13 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise

13 Days (12 Nights) Rome to Lisbon
Ship: Norwegian Epic
Departure: 01 November 2025
Countries Visited: Italy, Sicily, Spain, Morocco (+1 more), Portugal
Exclusive Solo Offer
INSIDE
$2,945
OCEANVIEW
-
BALCONY
$4,704
SUITE
$5,316
From 2,945
View Trip
11 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Ships: Norwegian Breakaway, Norwegian Escape
Departures: Jun 2024 to Oct 2025
Countries Visited: Spain, France, Italy, Sicily (+1 more), Malta
INSIDE
$2,590
OCEANVIEW
$2,665
BALCONY
$2,711
SUITE
$3,584
From 2,590
View Trip
8 Day Western Mediterranean with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 September 2025
Countries Visited: Spain, Sardinia, Corsica, Sicily (+1 more), Italy
INSIDE
$1,427
OCEANVIEW
$1,645
BALCONY
$1,873
SUITE
$3,833
From 1,427
View Trip
11 Day Greek Isles & Turkey with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 17 August 2024
Countries Visited: Italy, Greece, Turkey, Sicily (+1 more), Spain
Exclusive DealExclusive Offer
INSIDE
$2,244
OCEANVIEW
$5,440
BALCONY
$3,088
SUITE
$7,108
Save 3,074
From 2,154
View Trip
11 Day Greece, Italy & Spain with Celebrity Cruises
Cruise

11 Days (10 Nights) Athens to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Silhouette
Departure: 21 October 2024
Countries Visited: Greece, Turkey, Sicily, Italy (+1 more), Spain
Exclusive DealExclusive Offer
INSIDE
$2,679
OCEANVIEW
$3,024
BALCONY
$3,403
SUITE
$9,783
Save 3,369
From 2,679
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2026 to Jun 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sicily
INSIDE
$2,726
OCEANVIEW
$2,974
BALCONY
$3,370
SUITE
$7,231
From 2,726
View Trip
15 Day Mediterranean & Italian Sojourn with Viking Cruises
Cruise

15 Days (14 Nights) Venice to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+4 more), Viking Saturn, Viking Vela, Viking Venus, Viking Vesta
Departures: Sep 2024 to Sep 2026
Countries Visited: Italy, Croatia, Sicily, Monaco (+2 more), France, Spain
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$11,677
SUITE
$18,805
Save 2,050
From 11,677
View Trip
10 Day Nice to Valletta with Silversea
Cruise

10 Days (9 Nights) Nice to Valletta
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 07 September 2025
Countries Visited: France, Italy, Sardinia, Sicily (+1 more), Malta
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$12,177
BALCONY
$14,553
SUITE
$20,790
From 12,177
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaside
Departures: May 2024 to Oct 2025
Countries Visited: Sicily, Italy, France, Spain (+1 more), Tunisia
Mutiple Deals Available
INSIDE
$1,405
OCEANVIEW
$1,682
BALCONY
$1,890
SUITE
$2,474
From 1,405
View Trip
15 Day Italy, the Adriatic & Greece with Viking Cruises
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+5 more), Viking Saturn, Viking Sky, Viking Star, Viking Venus, Viking Vesta
Departures: Aug 2024 to Aug 2026
Countries Visited: Italy, Sicily, Croatia, Montenegro (+1 more), Greece
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$10,192
SUITE
$14,845
Save 2,062
From 10,192
View Trip
28 Day Lisbon to Athens with Silversea
Cruise

28 Days (27 Nights) Lisbon to Athens
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 30 September 2024
Countries Visited: Portugal, Spain, Sicily, Malta (+1 more), Greece
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$21,582
BALCONY
$24,354
SUITE
$44,154
From 21,582
View Trip
13 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

13 Days (12 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 21 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
INSIDE
$1,515
OCEANVIEW
$1,839
BALCONY
$2,599
SUITE
-
From 1,515
View Trip
11 Day Islands of the Mediterranean: Spain to Malta with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 25 April 2026
Countries Visited: Spain, Corsica, Sardinia, Sicily (+1 more), Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,489
BALCONY
-
SUITE
$14,449
Save 2,606
From 10,489
View Trip
10 Day A Journey from Barcelona to Rome with Explora Journeys
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 April 2025
Countries Visited: Spain, Sardinia, Tunisia, Sicily (+1 more), Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,073
SUITE
$11,098
From 12,157
View Trip
8 Day Italy And Adriatic with Cunard
Cruise

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Countries Visited: Spain, Italy, Sicily, Greece (+1 more), Montenegro
INSIDE
$1,783
OCEANVIEW
$1,981
BALCONY
$2,179
SUITE
$4,951
From 1,783
View Trip
10 Day Valletta to Nice with Silversea
Cruise

10 Days (9 Nights) Valletta to Nice
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 18 July 2025
Countries Visited: Malta, Sicily, Sardinia, Italy (+1 more), France
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,880
BALCONY
$14,454
SUITE
$20,790
From 11,880
View Trip
14 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

14 Days (13 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 20 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
INSIDE
$1,693
OCEANVIEW
$2,087
BALCONY
$2,817
SUITE
$4,598
From 1,693
View Trip
8 Day Mediterranean with Greece & Italy with Princess
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Jul 2024 to Aug 2024
Countries Visited: Greece, Montenegro, Sicily, Italy (+1 more), Spain
INSIDE
$2,296
OCEANVIEW
$2,524
BALCONY
$2,762
SUITE
$3,376
From 2,296
View Trip
8 Day Greek Isles, Italy, & France: European Jewels with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Rome to Venice
Ship: Norwegian Escape
Departure: 14 August 2024
Countries Visited: Italy, Sicily, Malta, Greece (+1 more), Croatia
INSIDE
$3,070
OCEANVIEW
$3,605
BALCONY
$4,186
SUITE
$4,293
From 3,070
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaside
Departures: May 2024 to Oct 2025
Countries Visited: France, Spain, Tunisia, Sicily (+1 more), Italy
Mutiple Deals Available
INSIDE
$1,464
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,474
From 1,464
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Naples to Naples
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaside
Departures: May 2024 to Oct 2025
Countries Visited: Italy, France, Spain, Tunisia (+1 more), Sicily
Mutiple Deals Available
INSIDE
$1,464
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,474
From 1,464
View Trip
Results: 151-180 of 241

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