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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 405 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. October is the most popular month to cruise to Sicily and we have over 2,306 departures available from twenty-four of the world's leading cruise lines.
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405 Cruises (2,306 Cruise Departures)
9 Day Croatia, Malta & Italy with Seabourn
Cruise

9 Days (8 Nights) Venice to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 13 June 2027
Visit: Italy, Croatia, Malta, Sicily
Yours to Explore
Inside
-
Oceanview
-
Balcony
$8,699
Suite
$12,799
From
US$8,699
Per Person
View Trip
8 Day Mediterranean Splendor: Corfu, Sicily & Spain with Holland America
Cruise
 (3)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 05 July 2026
Visit: Greece, Montenegro, Sicily, Spain
Fare Saver
Inside
$874
Oceanview
$924
Balcony
$1,274
Suite
$1,974
From
US$874
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 May 2026
Visit: Spain, Corsica, Sicily, Italy
Inside
$919
Oceanview
$919
Balcony
$1,129
Suite
$3,079
From
US$919
Per Person
View Trip
8 Day Italy, Greece And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Jun 2027 to Jul 2027
Visit: Italy, Croatia, Greece, Sicily
Bonus Onboard Credit
Inside
$1,239
Oceanview
$1,299
Balcony
$1,439
Suite
$2,569
From
US$1,239
Per Person
View Trip
8 Day Italy, Greece And Turkey with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 May 2027
Visit: Spain, Sicily, Greece, Turkey
Bonus Onboard Credit
Inside
$1,139
Oceanview
$1,369
Balcony
$1,429
Suite
$3,169
From
US$1,139
Per Person
View Trip
11 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (1)

11 Days (10 Nights) Athens to Istanbul
Cruise Line: Princess
Ship: Enchanted Princess
Departures: May 2027 to Oct 2027
Visit: Greece, Sicily, Malta, Turkey
Princess Standard
Inside
$1,725
Oceanview
$2,894
Balcony
$2,167
Suite
$2,460
From
US$1,725
Per Person
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise
 (1)

8 Days (7 Nights) Istanbul to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 28 September 2026
Visit: Turkey, Greece, Sicily, Italy
Bonus Onboard Credit
Inside
$1,539
Oceanview
$1,669
Balcony
$1,879
Suite
$5,649
From
US$1,539
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Rome to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 27 October 2026
Visit: Italy, Sicily, Greece, Montenegro
Inside
-
Oceanview
$539
Balcony
$689
Suite
$1,119
From
US$539
Per Person
View Trip
11 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (6)

11 Days (10 Nights) Athens to Istanbul
Cruise Line: Princess
Ship: Sun Princess
Departures: Jun 2027 to Jul 2027
Visit: Greece, Montenegro, Sicily, Turkey
Princess Standard
Sanctuary Collection
Inside
$1,304
Oceanview
$1,504
Balcony
$1,829
Suite
$2,209
From
US$1,304
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2027 to Aug 2027
Visit: Italy, Sicily, France, Spain
Inside
$1,069
Oceanview
$1,709
Balcony
$1,599
Suite
$1,779
From
US$1,069
Per Person
View Trip
9 Day Peaceful Islands and Ancient Treasures of the Mediterranean with Ponant
Cruise

9 Days (8 Nights) Valletta to Athens
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 14 June 2027
Visit: Malta, Sicily, Italy, Greece
Inside
-
Oceanview
-
Balcony
$6,910
Suite
$12,870
From
US$6,910
Per Person
View Trip
11 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 04 June 2027
Visit: Italy, Sicily, Montenegro, Croatia
Bonus Onboard Credit
Exclusive Savings
Inside
$1,941
Oceanview
$2,157
Balcony
$2,617
Suite
$9,008
From
US$2,952
Per Person
View Trip
13 Day Minarets & Mosaics with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Athens to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 05 July 2026
Visit: Greece, Turkey, Tunisia, Sicily, Monaco
Your World Inclusions
Exclusive Savings
Inside
$2,400
Oceanview
$2,640
Balcony
$3,960
Suite
$5,400
From
US$2,400
Save 5,598
Per Person
View Trip
8 Day Italy And Adriatic with Cunard
Cruise
 (1)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 06 July 2026
Visit: Italy, Croatia, Malta, Sicily
Inside
$1,229
Oceanview
$1,279
Balcony
$1,599
Suite
$2,969
From
US$1,229
Per Person
View Trip
11 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Bologna to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departures: May 2026 to Aug 2026
Visit: Italy, Croatia, Montenegro, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,699
Oceanview
$1,999
Balcony
$2,599
Suite
$4,798
From
US$2,555
Per Person
View Trip
11 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 06 August 2027
Visit: Italy, Sicily, Montenegro, Croatia
Bonus Onboard Credit
Exclusive Savings
Inside
$1,748
Oceanview
$1,849
Balcony
$2,130
Suite
$6,482
From
US$2,644
Per Person
View Trip
11 Day Breathtaking Greek Isles with Regent Seven Seas
Cruise

11 Days (10 Nights) Bologna to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 05 July 2027
Visit: Italy, Greece, Sicily, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,299
Suite
$12,999
From
US$12,299
Save 12,299
Per Person
View Trip
11 Day Monte Carlo to Rome with Silversea
Cruise

11 Days (10 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 08 October 2026
Visit: Monaco, France, Corsica, Italy, Sicily
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,400
Suite
$13,700
From
US$9,400
Save 1,500
Per Person
View Trip
11 Day Jewels of the Mediterranean with Scenic
New ReleaseCruise

11 Days (10 Nights) Palma de Mallorca to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 May 2027
Visit: Spain, Sardinia, Sicily, Malta
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,581
Suite
$19,466
From
US$12,581
Save 1,264
Per Person
View Trip
12 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Rome to Bologna
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 18 May 2026
Visit: Italy, Sicily, Montenegro, Croatia
Bonus Onboard Credit
Exclusive Savings
Inside
$2,149
Oceanview
$2,349
Balcony
$3,149
Suite
$6,099
From
US$3,290
Per Person
View Trip
10 Day From the Iberian Shores to the Italian Coast with Ponant
Cruise

10 Days (9 Nights) Malaga to Valletta
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 04 April 2027
Visit: Spain, Sicily, Italy, Malta
Inside
-
Oceanview
-
Balcony
$7,320
Suite
$13,610
From
US$7,320
Per Person
View Trip
8 Day Croatia, Montenegro & Italy with Seabourn
Cruise

8 Days (7 Nights) Dubrovnik to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 11 September 2027
Visit: Croatia, Montenegro, Sicily, Italy
Yours to Explore
Inside
-
Oceanview
-
Balcony
$6,899
Suite
$10,499
From
US$6,899
Per Person
View Trip
8 Day A Journey To Italian Hidden Gems & The Heartbeat Of Catalan Culture with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 May 2026
Visit: Italy, Sicily, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,520
From
US$5,520
Per Person
View Trip
8 Day Spotlight On Sparkling Wines with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 October 2026
Visit: Italy, Sicily, Malta, Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,499
Suite
$10,949
From
US$10,499
Save 10,499
Per Person
View Trip
12 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Bologna to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 26 July 2027
Visit: Italy, Croatia, Montenegro, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,955
Oceanview
$2,104
Balcony
$2,384
Suite
$6,991
From
US$2,944
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 20 April 2026
Visit: Italy, Sicily, Tunisia, Spain
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$1,783
From
US$1,783
Per Person
View Trip
7 Day Valletta to Nice with Silversea
Cruise

7 Days (6 Nights) Valletta to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: Apr 2026 to Aug 2026
Visit: Malta, Sicily, Italy, France
All-Inclusive Plus Fare
All-Inclusive Fare
Last Minute Fare
Exclusive Savings
Inside
-
Oceanview
$3,350
Balcony
$4,000
Suite
$10,900
From
US$3,350
Save 2,500
Per Person
View Trip
11 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Bologna to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departures: Jun 2026 to Oct 2026
Visit: Italy, Croatia, Montenegro, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,674
Oceanview
$1,949
Balcony
$2,799
Suite
$5,207
From
US$2,514
Per Person
View Trip
8 Day A Journey Of Historic Splendour & Stunning Landscapes with Explora Journeys
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2026
Visit: Monaco, Italy, Sicily, Malta, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,650
From
US$5,650
Per Person
View Trip
12 Day Best Of Italy & Croatia Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) Bologna to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departures: Aug 2027 to Sep 2027
Visit: Italy, Croatia, Montenegro, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,971
Oceanview
$2,120
Balcony
$2,400
Suite
$7,044
From
US$2,960
Per Person
View Trip
Results: 151-180 of 405

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