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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 384 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bologna and more. October is the most popular month to cruise to Sicily and we have over 2,193 departures available from twenty-four of the world's leading cruise lines.
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384 Cruises (2,193 Cruise Departures)
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 20 September 2026
Visit: Spain, France, Italy, Sicily
Inside
$1,099
Oceanview
-
Balcony
$1,649
Suite
$1,749
From
US$1,099
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise
 (2)

5 Days (4 Nights) Rome to Bari
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 27 October 2026
Visit: Italy, Sicily, Greece, Montenegro
Inside
$379
Oceanview
$489
Balcony
$599
Suite
$1,119
From
US$379
Per Person
View Trip
13 Day Mediterranean: Rome to Athens with Virgin Voyages
Cruise
 (1)

13 Days (12 Nights) Rome to Athens
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 07 September 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
Inside
$2,238
Oceanview
$2,508
Balcony
$2,748
Suite
$7,860
From
US$2,238
Per Person
View Trip
8 Day Italy & Croatia Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Bologna to Rome
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 30 October 2027
Visit: Italy, Croatia, Montenegro, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,137
Oceanview
$1,317
Balcony
$1,730
Suite
$2,265
From
US$1,137
Save 567
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Jun 2027 to Aug 2027
Visit: Italy, Sicily, France, Spain
Inside
$1,209
Oceanview
$1,629
Balcony
$1,699
Suite
$1,919
From
US$1,209
Per Person
View Trip
8 Day Italy And Adriatic with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Visit: Spain, Italy, Sicily, Greece, Montenegro
Inside
$899
Oceanview
$1,099
Balcony
$2,269
Suite
$3,009
From
US$899
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Virgin Voyages
Cruise
 (5)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departures: May 2027 to Sep 2027
Visit: Spain, France, Italy, Sicily
Inside
$1,323
Oceanview
$1,673
Balcony
$1,743
Suite
$4,200
From
US$1,323
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 22 July 2026
Visit: Italy, Sicily, Malta, Greece, Turkey
Inside
$1,709
Oceanview
$1,809
Balcony
$2,309
Suite
$3,359
From
US$1,709
Per Person
View Trip
11 Day Italy, France & Malta Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 10 October 2026
Visit: Spain, Malta, Sicily, Italy, France
Exclusive Savings
Inside
$1,289
Oceanview
$1,645
Balcony
$1,766
Suite
$4,321
From
US$1,289
Save 732
Per Person
View Trip
8 Day Mykonos Moons and Italian Sunrises with Virgin Voyages
Cruise
 (1)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 04 October 2026
Visit: Greece, Sicily, Italy, Spain
Inside
$2,142
Oceanview
-
Balcony
$2,605
Suite
$11,445
From
US$2,605
Per Person
View Trip
9 Day From Malta to the Shores of the Adriatic with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 19 August 2027
Visit: Malta, Sicily, Italy, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$6,840
Suite
$12,090
From
US$6,840
Per Person
View Trip
9 Day Authentic Mediterranean Shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 06 June 2027
Visit: Malta, Sicily, Italy
Inside
-
Oceanview
$6,300
Balcony
$6,630
Suite
$12,350
From
US$6,300
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Amalfi to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Mar 2027 to Jan 2028
Visit: Italy, Sicily, Malta, Spain, France
Inside
$791
Oceanview
$951
Balcony
$1,081
Suite
$1,601
From
US$791
Per Person
View Trip
8 Day Italy And Adriatic with Cunard
Cruise
 (1)

8 Days (7 Nights) Trieste to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 06 July 2026
Visit: Italy, Croatia, Malta, Sicily
Inside
$899
Oceanview
$1,199
Balcony
$1,499
Suite
$2,949
From
US$899
Per Person
View Trip
6 Day Sicilian interlude with Ponant
Cruise
 (2)

6 Days (5 Nights) Palermo to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 01 June 2027
Visit: Sicily, Italy, Malta
Inside
-
Oceanview
$3,940
Balcony
$4,150
Suite
$7,720
From
US$3,940
Per Person
View Trip
8 Day Greece, Italy And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 22 October 2027
Visit: Italy, Greece, Sicily, Spain
Value Fare
Inside
$1,399
Oceanview
$1,599
Balcony
$1,899
Suite
$4,049
From
US$1,399
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Mar 2027 to Jan 2028
Visit: Italy, Sicily, Malta, Spain, France
Inside
$839
Oceanview
$999
Balcony
$1,129
Suite
$1,649
From
US$839
Per Person
View Trip
11 Day Rome, Florence, Mykonos & More with Virgin Voyages
Cruise
 (1)

11 Days (10 Nights) Rome to Athens
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 31 August 2026
Visit: Italy, Sicily, Greece
Inside
$2,790
Oceanview
$3,190
Balcony
$3,790
Suite
$5,990
From
US$2,790
Per Person
View Trip
8 Day Adriatic Reflections with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 April 2027
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,599
Oceanview
$3,349
Balcony
$3,499
Suite
$4,899
From
US$2,599
Save 2,599
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 27 May 2026
Visit: Italy, Sicily, Malta, Greece, Turkey
Inside
$1,319
Oceanview
$1,359
Balcony
$1,489
Suite
$3,139
From
US$1,319
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Oct 2026
Visit: France, Italy, Sicily, Spain
Inside
$600
Oceanview
$770
Balcony
$940
Suite
$1,649
From
US$600
Per Person
View Trip
11 Day Mediterranean & Egypt Cruise: Alexandria, Heraklion & Rome with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 December 2026
Visit: Greece, Egypt, Malta, Sicily, Italy
Azamara Always Included
Inside
$2,189
Oceanview
$2,009
Balcony
$2,299
Suite
$3,609
From
US$2,009
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 05 November 2026
Visit: Spain, France, Italy, Sicily
Inside
$1,006
Oceanview
$1,116
Balcony
$1,286
Suite
$1,796
From
US$1,006
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Naples to Naples
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Jun 2026 to Oct 2027
Visit: Italy, Sicily, Malta, Spain, France
Inside
$1,250
Oceanview
$1,450
Balcony
$1,570
Suite
$2,300
From
US$1,250
Per Person
View Trip
8 Day Italy And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Visit: Spain, Sardinia, Sicily, Italy
Inside
$1,329
Oceanview
$1,449
Balcony
$1,629
Suite
$2,649
From
US$1,329
Per Person
View Trip
10 Day Exploring Ancient Empires with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 29 March 2027
Visit: Italy, Sicily, Greece, Turkey
Your World Inclusions
Exclusive Savings
Inside
$2,250
Oceanview
$2,520
Balcony
$3,960
Suite
$5,760
From
US$2,250
Save 2,748
Per Person
View Trip
15 Day Mediterranean, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Bonus Onboard Credit
Value Fare
Inside
$2,399
Oceanview
$2,699
Balcony
$2,859
Suite
$6,119
From
US$2,399
Per Person
View Trip
8 Day Mediterranean with Greece & Adriatic with Princess
Cruise
 (7)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Jun 2026 to Oct 2027
Visit: Greece, Montenegro, Sicily, Spain
Princess Standard
Princess Premier
Sanctuary Collection
Inside
$1,079
Oceanview
$1,169
Balcony
$1,619
Suite
$1,819
From
US$1,079
Per Person
View Trip
11 Day Italy Intensive Cruise: Amalfi, Siracusa & Venice with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 23 September 2028
Visit: Italy, Sicily, Montenegro, Croatia
Azamara Always Included
Inside
$2,559
Oceanview
$2,789
Balcony
$3,419
Suite
$4,809
From
US$2,559
Per Person
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Athens
Cruise Line: Royal Caribbean
Ships: Brilliance of the Seas, Explorer of the Seas
Departures: May 2026 to Sep 2027
Visit: Italy, Sicily, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$1,116
Oceanview
$1,546
Balcony
$1,878
Suite
$2,453
From
US$1,116
Save 981
Per Person
View Trip
Results: 91-120 of 384

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