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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 384 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bologna and more. October is the most popular month to cruise to Sicily and we have over 2,193 departures available from twenty-four of the world's leading cruise lines.
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384 Cruises (2,193 Cruise Departures)
10 Day Italy & Greece Cruise with Celebrity Cruises
Cruise
 (3)

10 Days (9 Nights) Barcelona to Athens
Cruise Line: Celebrity Cruises
Ship: Celebrity Infinity
Departure: 01 April 2028
Visit: Spain, Italy, Sicily, Greece
Exclusive Savings
Inside
$1,482
Oceanview
$1,722
Balcony
$2,217
Suite
$4,924
From
US$1,482
Save 811
Per Person
View Trip
13 Day Sweet Mediterranean Escape with Ponant
Cruise
 (2)

13 Days (12 Nights) Athens to Nice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 17 July 2026
Visit: Greece, Sicily, Italy, Corsica, France
Inside
-
Oceanview
-
Balcony
$9,770
Suite
$18,170
From
US$9,770
Per Person
View Trip
12 Day Italy Intensive Cruise: Bologna, Sicily & Amalfi with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Venice to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 16 May 2027
Visit: Italy, Montenegro, Sicily
Azamara Always Included
Inside
$3,939
Oceanview
$4,529
Balcony
$6,209
Suite
$8,579
From
US$3,939
Per Person
View Trip
11 Day Greek Isles & Turkey Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 15 August 2026
Visit: Spain, Sicily, Greece, Turkey, Italy
Exclusive Savings
Inside
$1,745
Oceanview
$1,852
Balcony
$2,012
Suite
$3,679
From
US$1,745
Save 1,029
Per Person
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ships: Emerald Azzurra, Emerald Kaia
Departures: May 2027 to Oct 2027
Visit: Italy, Sicily, Malta
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
$7,400
Balcony
-
Suite
$10,179
From
US$7,400
Save 1,895
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 November 2026
Visit: Italy, Sicily, Spain, France
Inside
$1,135
Oceanview
$1,265
Balcony
$1,405
Suite
$1,915
From
US$1,135
Per Person
View Trip
9 Day Italy Intensive Cruise: Rome, Amalfi & Venice with Azamara Cruises
Cruise
 (5)

9 Days (8 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 09 October 2028
Visit: Italy, Sicily, Montenegro
Azamara Always Included
Inside
$2,139
Oceanview
$2,209
Balcony
$2,669
Suite
$3,689
From
US$2,139
Per Person
View Trip
8 Day Greece And Italy with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey
Bonus Onboard Credit
Value Fare
Inside
$1,319
Oceanview
$1,429
Balcony
$1,549
Suite
$3,229
From
US$1,319
Per Person
View Trip
8 Day Italy, Greece & Malta Cruise with Celebrity Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Athens
Cruise Line: Celebrity Cruises
Ship: Celebrity Infinity
Departure: 15 March 2027
Visit: Spain, Malta, Sicily, Greece
Exclusive Savings
Inside
$1,310
Oceanview
$1,623
Balcony
$2,193
Suite
$4,342
From
US$1,310
Save 757
Per Person
View Trip
11 Day Greece, Italy & Malta Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Oct 2026 to Nov 2026
Visit: Spain, Malta, Greece, Sicily, Italy
Exclusive Savings
Inside
$1,212
Oceanview
$1,366
Balcony
$1,652
Suite
$4,415
From
US$1,212
Save 718
Per Person
View Trip
11 Day Italy, Montenegro & Croatia Cruise: Rome, Kotor & Dubrovnik with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 31 October 2027
Visit: Spain, Italy, Sicily, Montenegro, Croatia
Azamara Always Included
Inside
$3,989
Oceanview
$4,859
Balcony
$5,999
Suite
$8,759
From
US$3,989
Per Person
View Trip
8 Day Mediterranean, Greece And Croatia with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2028 to Sep 2028
Visit: Italy, Croatia, Greece, Sicily, Spain
Cunard Fare
Value Fare
Inside
$1,659
Oceanview
$1,794
Balcony
$2,154
Suite
$4,179
From
US$1,659
Per Person
View Trip
12 Day Greece & Italy Cruise: Rhodes, Crete & Amalfi with Azamara Cruises
Cruise
 (8)

12 Days (11 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 26 July 2028
Visit: Greece, Turkey, Sicily, Italy
Azamara Always Included
Inside
$3,379
Oceanview
$3,659
Balcony
$4,519
Suite
$6,389
From
US$3,379
Per Person
View Trip
9 Day Legendary Shores of Italy and Croatia with Ponant
Cruise
 (2)

9 Days (8 Nights) Rome to Venice
Cruise Line: Ponant
Ship: Le Boreal
Departure: 12 May 2027
Visit: Italy, Sicily, Croatia
Inside
-
Oceanview
$6,650
Balcony
$7,010
Suite
$13,080
From
US$6,650
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Naples to Naples
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Mar 2028
Visit: Italy, Sicily, Tunisia, Spain, France
Inside
$614
Oceanview
$753
Balcony
$853
Suite
$1,593
From
US$614
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 08 November 2027
Visit: France, Italy, Sicily, Malta, Spain
Inside
$1,021
Oceanview
$1,181
Balcony
$1,311
Suite
$1,831
From
US$1,021
Per Person
View Trip
15 Day Mediterranean with Total Solar Eclipse with Princess
Cruise
 (2)

15 Days (14 Nights) Rome to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 24 July 2027
Visit: Italy, France, Spain, Gibraltar, Sicily
Princess Standard
Inside
$6,629
Oceanview
$7,728
Balcony
$7,401
Suite
$7,979
From
US$6,629
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Mar 2028
Visit: Sicily, Tunisia, Spain, France, Italy
Inside
$614
Oceanview
$814
Balcony
$914
Suite
$1,654
From
US$614
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$824
Oceanview
$924
Balcony
$1,104
Suite
-
From
US$824
Per Person
View Trip
10 Day A Journey To Spain's Icons & North Africa's Sunlit Shores with Explora Journeys
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 February 2027
Visit: Italy, Sicily, Tunisia, Algeria, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$4,865
From
US$4,865
Per Person
View Trip
8 Day Mediterranean, Croatia And Greece with Cunard
Cruise
 (13)

8 Days (7 Nights) Trieste to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 16 June 2028
Visit: Italy, Croatia, Greece, Sicily, Spain
Cunard Fare
Value Fare
Inside
$1,704
Oceanview
$1,929
Balcony
$2,379
Suite
$4,314
From
US$1,704
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departures: Oct 2026 to Mar 2028
Visit: Spain, France, Italy, Sicily, Tunisia
Inside
$631
Oceanview
$749
Balcony
$849
Suite
$1,589
From
US$631
Per Person
View Trip
15 Day Italy, the Adriatic & Greece with Viking Cruises
Cruise
 (1)

15 Days (14 Nights) Rome to Athens
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+7 more), Viking Mira, Viking Neptune, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Nov 2026 to Jul 2028
Visit: Italy, Sicily, Croatia, Montenegro, Greece
Viking $1,299 Air Deal
Viking $1,499 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,798
Suite
$10,498
From
US$7,798
Save 1,800
Per Person
View Trip
8 Day Greece And Turkiye with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 26 May 2028
Visit: Italy, Sicily, Greece, Turkey
Cunard Fare
Value Fare
Inside
$1,819
Oceanview
$1,909
Balcony
$2,359
Suite
$4,564
From
US$1,819
Per Person
View Trip
12 Day Mediterranean with Greek Isles & Turkey with Princess
Cruise
 (2)

12 Days (11 Nights) Athens to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 25 September 2026
Visit: Greece, Turkey, Sicily, Malta, Italy
Princess Standard
Inside
$3,094
Oceanview
$3,144
Balcony
$2,983
Suite
$3,199
From
US$2,983
Per Person
View Trip
11 Day Enchanting Greece & the Amalfi Coast with Emerald Cruises
New ReleaseCruise
 (3)

11 Days (10 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 17 October 2026
Visit: Greece, Sicily, Malta, Italy
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$25,145
From
US$25,145
Save 1,800
Per Person
View Trip
12 Day Tales Of The Ancients with Oceania Cruises
Cruise
 (1)

12 Days (11 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 16 June 2027
Visit: Turkey, Greece, Malta, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,549
Oceanview
$3,799
Balcony
$5,899
Suite
$8,299
From
US$3,549
Save 3,549
Per Person
View Trip
8 Day Journey to Antiquities with Viking Cruises
Cruise
 (7)

8 Days (7 Nights) Athens to Rome
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+8 more), Viking Libra, Viking Mira, Viking Neptune, Viking Saturn, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Oct 2026 to Apr 2028
Visit: Greece, Turkey, Sicily, Italy
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,499
From
US$2,599
Save 500
Per Person
View Trip
15 Day Solar Eclipse & Astronomical Discovery with Holland America
Cruise
 (3)

15 Days (14 Nights) Athens to Athens
Cruise Line: Holland America
Ship: Oosterdam
Departure: 31 July 2027
Visit: Greece, Tunisia, Malta, Sardinia, Sicily
Book Early & Have It All Fare Option
Inside
$4,414
Oceanview
$4,654
Balcony
$7,479
Suite
-
From
US$4,414
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Istanbul
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departures: Jul 2027 to Aug 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
Inside
$2,249
Oceanview
$2,709
Balcony
$3,169
Suite
$4,179
From
US$2,249
Per Person
View Trip
Results: 61-90 of 384

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