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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 404 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. October is the most popular month to cruise to Sicily and we have over 2,304 departures available from twenty-four of the world's leading cruise lines.
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404 Cruises (2,304 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: MSC Cruises
Ships: MSC World Asia, MSC World Europa
Departures: Apr 2026 to Oct 2027
Visit: Malta, Spain, France, Italy, Sicily
Inside
$1,134
Oceanview
$1,281
Balcony
$1,443
Suite
$2,454
From
US$1,134
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (3)

7 Days (6 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 19 April 2026
Visit: Italy, Sicily, Malta, Spain, France
Inside
-
Oceanview
-
Balcony
$889
Suite
$2,479
From
US$889
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Jan 2028
Visit: France, Italy, Sicily, Malta, Spain
Inside
$791
Oceanview
$951
Balcony
$1,081
Suite
$1,601
From
US$791
Per Person
View Trip
15 Day Villas & Venice with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 June 2027
Visit: Italy, Sicily, Croatia, Montenegro, Greece
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,099
Suite
$18,499
From
US$17,099
Save 17,099
Per Person
View Trip
10 Day Western Med: Barcelona to Rome with Virgin Voyages
Cruise
 (5)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 08 August 2027
Visit: Spain, France, Italy, Sicily, Malta
Limited Time Offer
Inside
$2,407
Oceanview
$2,705
Balcony
$2,875
Suite
-
From
US$2,407
Per Person
View Trip
11 Day Mediterranean & Egypt Cruise: Alexandria, Heraklion & Rome with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Athens to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 12 December 2026
Visit: Greece, Egypt, Malta, Sicily, Italy
Azamara Always Included
Inside
$2,329
Oceanview
$2,689
Balcony
$3,089
Suite
$4,909
From
US$2,329
Per Person
View Trip
8 Day Adriatic & Greece From Bologna To Rome with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Bologna to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 02 August 2026
Visit: Italy, Croatia, Montenegro, Greece, Sicily
Inside
$1,049
Oceanview
$1,229
Balcony
$1,649
Suite
$1,679
From
US$1,049
Per Person
View Trip
8 Day Exploring Italy, Malta & Montenegro with Seabourn
Cruise

8 Days (7 Nights) Rome to Dubrovnik
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Apr 2028 to Aug 2028
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$4,949
Suite
$8,099
From
US$4,949
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Apr 2026 to Mar 2028
Visit: Italy, Sicily, Tunisia, Spain, France
Inside
$736
Oceanview
$942
Balcony
$1,042
Suite
$1,782
From
US$736
Per Person
View Trip
11 Day Eastbound Adventure with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 18 October 2027
Visit: Italy, Sicily, Malta, Greece, Turkey
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,149
Oceanview
$3,949
Balcony
$4,699
Suite
$6,699
From
US$3,149
Save 3,149
Per Person
View Trip
8 Day Italy & France Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 03 August 2026
Visit: Spain, France, Corsica, Italy, Sicily
Exclusive Savings
Inside
$1,081
Oceanview
$1,251
Balcony
$1,513
Suite
$2,738
From
US$1,081
Save 554
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Apr 2026 to Mar 2028
Visit: Spain, France, Italy, Sicily, Tunisia
Inside
$736
Oceanview
$936
Balcony
$1,036
Suite
$1,776
From
US$736
Per Person
View Trip
12 Day Best Of Italy, France & Spain with Celebrity Cruises
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 24 May 2027
Visit: Spain, Corsica, France, Italy, Sicily
Exclusive Savings
Inside
$2,329
Oceanview
$2,375
Balcony
$2,847
Suite
$8,571
From
US$2,329
Save 1,308
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Magnifica, MSC World Asia, MSC World Europa
Departures: Apr 2026 to Oct 2027
Visit: Italy, Sicily, Malta, Spain, France
Inside
$661
Oceanview
$773
Balcony
$923
Suite
$1,653
From
US$661
Per Person
View Trip
9 Day From Malta to the Shores of the Adriatic with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 19 August 2027
Visit: Malta, Sicily, Italy, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$6,510
Suite
$12,090
From
US$6,510
Per Person
View Trip
12 Day Mediterranean with Greek Isles & Italy with Princess
Cruise
 (1)

12 Days (11 Nights) Istanbul to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departures: Jun 2027 to Sep 2027
Visit: Turkey, Greece, Malta, Sicily, Italy
Princess Standard
Inside
$1,535
Oceanview
-
Balcony
$1,945
Suite
$2,490
From
US$1,535
Per Person
View Trip
8 Day Italy And Adriatic with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Visit: Spain, Italy, Sicily, Greece, Montenegro
Inside
$1,249
Oceanview
$1,399
Balcony
$1,629
Suite
$3,009
From
US$1,249
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Euribia
Departure: 23 October 2027
Visit: Spain, France, Italy, Sicily, Tunisia
Inside
$1,003
Oceanview
$1,153
Balcony
$1,253
Suite
$2,023
From
US$1,003
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Palermo to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 12 November 2027
Visit: Sicily, Italy, France, Spain, Brazil
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$8,575
From
US$8,575
Per Person
View Trip
11 Day The Eternal Aegean with Ponant
Cruise
 (2)

11 Days (10 Nights) Valletta to Istanbul
Cruise Line: Ponant
Ship: Le Boreal
Departure: 14 May 2026
Visit: Malta, Sicily, Italy, Greece, Turkey
Inside
-
Oceanview
-
Balcony
$9,970
Suite
-
From
US$9,970
Per Person
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 18 May 2026
Visit: Turkey, Greece, Malta, Sicily, Italy
Inside
$1,599
Oceanview
$1,919
Balcony
$2,279
Suite
$2,749
From
US$1,599
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 17 October 2027
Visit: Spain, Tunisia, Malta, Sicily, Italy
Inside
$1,149
Oceanview
-
Balcony
$1,589
Suite
$1,909
From
US$1,149
Per Person
View Trip
15 Day Mediterranean, Greek Islands And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia, Spain
Inside
$2,629
Oceanview
$2,929
Balcony
$3,579
Suite
$7,979
From
US$2,629
Per Person
View Trip
12 Day Best Of Italy & Greece Cruise with Royal Caribbean
Cruise
 (1)

12 Days (11 Nights) Barcelona to Athens
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 03 May 2027
Visit: Spain, Italy, Sicily, Greece, Turkey
Bonus Onboard Credit
Exclusive Savings
Inside
$2,349
Oceanview
$2,699
Balcony
$4,979
Suite
$7,922
From
US$2,349
Save 895
Per Person
View Trip
13 Day Total Eclipse of the (Med) with Virgin Voyages
Cruise
 (1)

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 10 August 2026
Visit: Spain, France, Corsica, Italy, Sicily
Limited Time Offer
Inside
$3,229
Oceanview
$3,108
Balcony
$3,229
Suite
$8,090
From
US$3,108
Per Person
View Trip
8 Day Mediterranean Wayfarer with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Trieste
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 06 June 2026
Visit: Italy, Sicily, Greece, Montenegro, Croatia
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,699
Suite
-
From
US$4,699
Save 4,699
Per Person
View Trip
11 Day Civitavecchia (Rome) to Fusina (Venice) with Silversea
Cruise

11 Days (10 Nights) Rome to Venice
Cruise Line: Silversea
Ship: Silver Muse
Departure: 23 June 2026
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Last Minute Fare
All-Inclusive Plus Fare
All-Inclusive Fare
Inside
-
Oceanview
$6,250
Balcony
$7,050
Suite
$17,900
From
US$6,250
Per Person
View Trip
8 Day Valletta to Lisbon with Silversea
Cruise

8 Days (7 Nights) Valletta to Lisbon
Cruise Line: Silversea
Ship: Silver Muse
Departure: 14 October 2026
Visit: Malta, Sicily, Sardinia, Spain, Portugal
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$6,800
Balcony
$7,500
Suite
$9,400
From
US$6,800
Save 2,500
Per Person
View Trip
8 Day A Journey of Iconic Islands & Coastal Wonders with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departures: May 2027 to Oct 2027
Visit: Spain, Tunisia, Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$4,450
From
US$4,450
Per Person
View Trip
8 Day A Journey Through Fortresses, Medinas and Balearic Splendour with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 02 January 2028
Visit: Italy, Sicily, Malta, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$4,735
From
US$4,735
Per Person
View Trip
Results: 331-360 of 404

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