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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 357 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bari and more. October is the most popular month to cruise to Sicily and we have over 2,318 departures available from twenty-four of the world's leading cruise lines.
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357 Cruises (2,318 Cruise Departures)
8 Day Italy & France Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Bologna
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departures: May 2027 to Sep 2027
Visit: Spain, France, Corsica, Italy, Sicily
Bonus Onboard Credit
Exclusive Savings
Inside
$1,070
Oceanview
$1,451
Balcony
$1,733
Suite
$2,183
From
US$1,070
Save 541
Per Person
View Trip
12 Day Greek Isles, Turkey & The Pyramids with Scenic
New ReleaseCruise

12 Days (11 Nights) Athens to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 25 June 2027
Visit: Greece, Turkey, Egypt, Sicily, Malta
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,169
Suite
$20,583
From
US$16,169
Save 20,221
Per Person
View Trip
8 Day Croatia, Malta & Italy with Seabourn
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 02 October 2027
Visit: Italy, Sicily, Malta, Montenegro, Croatia
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,760
Suite
$9,175
From
US$5,760
Save 104
Per Person
View Trip
15 Day Sea Of Legacy with Regent Seven Seas
Cruise

15 Days (14 Nights) Venice to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 29 July 2027
Visit: Italy, Croatia, Greece, Turkey, Sicily
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,068
Suite
$13,803
From
US$13,068
Save 20,530
Per Person
View Trip
10 Day Medieval Mediterranean with Oceania Cruises
Cruise

10 Days (9 Nights) Istanbul to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 19 February 2028
Visit: Turkey, Greece, Malta, Sicily, Italy
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,374
Suite
$5,168
From
US$3,374
Save 3,524
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise

7 Days (6 Nights) Barcelona to Marseille
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 05 May 2026
Visit: Spain, Tunisia, Sicily, Italy, France
Exclusive Savings
Inside
$849
Oceanview
-
Balcony
-
Suite
$2,730
From
US$2,730
Save 79
Per Person
View Trip
9 Day Italy, France & Tunisia with Seabourn
Cruise

9 Days (8 Nights) Genoa to Rome
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 April 2027
Visit: Italy, Corsica, Sardinia, Tunisia, Sicily
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,621
Suite
$10,011
From
US$5,621
Save 98
Per Person
View Trip
8 Day Mediterranean with Greece & Italy with Princess
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 29 March 2026
Visit: Italy, Albania, Greece, Malta, Sicily
Princess Standard
Inside
-
Oceanview
-
Balcony
$2,151
Suite
-
From
US$2,151
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departures: May 2026 to Jun 2026
Visit: France, Italy, Malta, Sicily, Corsica
All-Inclusive Fare
Last Minute Fare
Exclusive Savings
Inside
-
Oceanview
$7,550
Balcony
$8,050
Suite
$15,460
From
US$7,550
Save 5,520
Per Person
View Trip
11 Day Italian Celebration with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 May 2027
Visit: Spain, France, Monaco, Italy, Sicily, Sardinia
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,644
Suite
$9,673
From
US$8,644
Save 14,954
Per Person
View Trip
18 Day Discover Scenic Shores and Hidden Gems with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Valletta to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 30 June 2027
Visit: Malta, Sicily, Italy, Corsica, Monaco, France
Fly Free Economy
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
$16,299
Balcony
-
Suite
$21,416
From
US$16,299
Save 17,181
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Feb 2026 to Mar 2028
Visit: France, Italy, Sicily, Tunisia, Spain
Bonus Onboard Credit
Drinks, WiFi & Onboard Credit
Exclusive Savings
Inside
$678
Oceanview
$940
Balcony
$838
Suite
$1,448
From
US$678
Save 71
Per Person
View Trip
10 Day Greek & Italian Isles with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 06 October 2027
Visit: Italy, Sicily, Tunisia, Malta, Greece
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,050
Suite
$5,844
From
US$4,050
Save 4,248
Per Person
View Trip
13 Day Nice to Nice with Silversea
Cruise

13 Days (12 Nights) Nice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 01 April 2027
Visit: France, Italy, Malta, Sicily, Corsica
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$6,370
Balcony
$7,770
Suite
$14,850
From
US$6,370
Save 2,730
Per Person
View Trip
11 Day Islands of the Mediterranean: Spain to Malta with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 25 April 2026
Visit: Spain, Corsica, Sardinia, Sicily, Malta
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$9,668
From
US$9,668
Save 12,222
Per Person
View Trip
8 Day Malta, Italy & Spain with Seabourn
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 30 October 2027
Visit: Greece, Malta, Sicily, Sardinia, Spain
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,253
Suite
$9,094
From
US$5,253
Save 92
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Palermo to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 12 November 2027
Visit: Sicily, Italy, France, Spain, Brazil
Drinks, WiFi & Onboard Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$8,335
From
US$8,335
Save 240
Per Person
View Trip
8 Day Barcelona to Rome with Silversea
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 07 September 2026
Visit: Spain, Sardinia, Tunisia, Sicily, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$5,280
Balcony
$6,160
Suite
$8,410
From
US$5,280
Save 1,320
Per Person
View Trip
9 Day Adriatic Jewel with Regent Seven Seas
Cruise

9 Days (8 Nights) Rome to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 11 July 2027
Visit: Italy, Sicily, Montenegro, Croatia, Slovenia
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,571
Suite
$8,453
From
US$7,571
Save 12,827
Per Person
View Trip
15 Day A Holiday To Remember with Oceania Cruises
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 20 December 2027
Visit: Spain, Morocco, Tunisia, Sicily, Italy
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,047
Suite
$8,278
From
US$6,047
Save 6,351
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Feb 2026 to Mar 2028
Visit: Sicily, Tunisia, Spain, France, Italy
Bonus Onboard Credit
Inside
$721
Oceanview
$951
Balcony
$762
Suite
$1,372
From
US$721
Per Person
View Trip
15 Day Idyllic Days with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 09 September 2027
Visit: Italy, Sicily, Montenegro, Croatia, Greece
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,606
Suite
$13,998
From
US$13,606
Save 21,092
Per Person
View Trip
15 Day Harbors Of Heritage with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 22 July 2027
Visit: Italy, Sicily, Montenegro, Croatia, Greece
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,655
Suite
$13,900
From
US$13,655
Save 21,143
Per Person
View Trip
8 Day From the French City of Angels to the Shores of the Adriatic with Ponant
Cruise

8 Days (7 Nights) Nice to Dubrovnik
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 08 June 2026
Visit: France, Italy, Sicily, Montenegro, Croatia
Inside
-
Oceanview
-
Balcony
$6,940
Suite
$12,350
From
US$6,940
Per Person
View Trip
8 Day Barcelona to Rome with Silversea
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 01 November 2026
Visit: Spain, Sardinia, Tunisia, Sicily, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$3,760
Balcony
$4,400
Suite
$9,280
From
US$3,760
Save 940
Per Person
View Trip
11 Day Fusina (Venice) to Nice with Silversea
Cruise

11 Days (10 Nights) Venice to Nice
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 07 May 2027
Visit: Italy, Croatia, Sicily, Malta, France
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$5,840
Balcony
$7,200
Suite
$12,760
From
US$5,840
Save 1,460
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Feb 2026 to Mar 2028
Visit: Spain, France, Italy, Sicily, Tunisia
Bonus Onboard Credit
Inside
$769
Oceanview
$946
Balcony
$956
Suite
$1,216
From
US$769
Per Person
View Trip
Results: 331-357 of 357

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