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Cruises from Italy to Portugal

Are you looking for a cruise from Italy to Portugal? November is the most popular month to cruise between Italy and Portugal and there are 30 departures available from nine of the world's leading cruise lines.
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29 Cruises (30 Cruise Departures)
Cruise
 (1)

20 Days (19 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Departure: 02 December 2026
Countries Visited: Italy, Corsica, France, Spain (+3 more), Gibraltar, Morocco, Portugal
Exclusive Deal
INSIDE
$7,470
OCEANVIEW
$8,213
BALCONY
$12,232
SUITE
$17,152
Save (per person) 2,050
From (per person) 7,470
Cruise
 (1)

12 Days (11 Nights) Genoa to Funchal
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 02 November 2025
Countries Visited: Italy, France, Spain, Gibraltar (+2 more), Portugal, Morocco
Early Booking Offer
INSIDE
$1,654
OCEANVIEW
$1,887
BALCONY
$2,401
SUITE
-
From (per person) 1,654
Cruise
 (1)

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Departure: 18 November 2024
Countries Visited: Italy, France, Spain, Gibraltar (+1 more), Portugal
More At Sea Offer
INSIDE
$2,116
OCEANVIEW
$2,437
BALCONY
$2,742
SUITE
$5,933
From (per person) 2,116
Cruise
 (1)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Departure: 18 November 2025
Countries Visited: Italy, France, Spain, Portugal
More At Sea Offer
INSIDE
$4,149
OCEANVIEW
$5,037
BALCONY
$5,526
SUITE
$7,698
From (per person) 4,149
Cruise
 (1)

6 Days (5 Nights) Genoa to Lisbon
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 26 April 2025
Countries Visited: Italy, France, Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$1,086
SUITE
-
From (per person) 1,086
Cruise
 (2)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Departure: 22 May 2025
Countries Visited: Italy, France, Spain, Gibraltar (+1 more), Portugal
INSIDE
$4,594
OCEANVIEW
$5,069
BALCONY
$5,346
SUITE
$7,416
From (per person) 4,594
Cruise
 (2)

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 24 May 2026
Countries Visited: Italy, Sicily, Sardinia, Spain (+2 more), Gibraltar, Portugal
Have It All Offer
INSIDE
$2,726
OCEANVIEW
$2,973
BALCONY
$4,013
SUITE
$5,547
From (per person) 2,726
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Departure: 01 November 2025
Countries Visited: Italy, Sicily, Spain, Morocco (+1 more), Portugal
More At Sea OfferExclusive Solo Offer
INSIDE
$3,617
OCEANVIEW
-
BALCONY
$5,100
SUITE
$5,635
From (per person) 3,617
Cruise
 (2)

25 Days (24 Nights) Venice to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 19 June 2025
Countries Visited: Italy, Croatia, Montenegro, Greece (+7 more), Sicily, Malta, Tunisia, Sardinia, Spain, Morocco, Portugal
Exclusive Deal
INSIDE
$5,653
OCEANVIEW
$6,494
BALCONY
$8,128
SUITE
$11,494
From (per person) 5,653
Cruise
 (2)

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 26 July 2026
Countries Visited: Italy, France, Gibraltar, Spain (+2 more), Morocco, Portugal
Have It All Offer
INSIDE
$3,579
OCEANVIEW
$4,173
BALCONY
$5,163
SUITE
$8,084
From (per person) 3,579
Cruise
 (2)

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 29 June 2025
Countries Visited: Italy, Sicily, Greece, Malta (+5 more), Tunisia, Sardinia, Spain, Morocco, Portugal
Exclusive Deal
INSIDE
$3,431
OCEANVIEW
$3,926
BALCONY
$4,916
SUITE
$6,698
From (per person) 3,431
Cruise
 (3)

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Departure: 18 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+5 more), Monaco, France, Spain, Portugal, Morocco
Bonus SavingsExclusive Deal
INSIDE
$7,239
OCEANVIEW
$7,944
BALCONY
$12,054
SUITE
$16,719
Save (per person) 2,431
From (per person) 7,239
Cruise
 (1)

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Azamara Cruises
Departure: 20 May 2025
Countries Visited: Italy, Corsica, France, Spain (+2 more), Gibraltar, Portugal
INSIDE
$6,240
OCEANVIEW
$6,567
BALCONY
$7,438
SUITE
$10,774
From (per person) 6,240
Cruise
 (2)

21 Days (20 Nights) Trieste to Lisbon
Cruise Line: Holland America
Ship: Oosterdam
Departure: 14 May 2026
Countries Visited: Italy, Croatia, Montenegro, Greece (+5 more), Sicily, Sardinia, Spain, Gibraltar, Portugal
Have It All Offer
INSIDE
$5,156
OCEANVIEW
$5,601
BALCONY
$7,631
SUITE
$10,601
From (per person) 5,156
New ReleaseCruise
 (3)

12 Days (11 Nights) Rome to Lisbon
Cruise Line: Emerald Cruises
Departure: 27 October 2026
Countries Visited: Italy, Corsica, Spain, Morocco (+1 more), Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
$12,222
BALCONY
-
SUITE
$16,627
Save (per person) 2,623
From (per person) 12,222
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Silversea
Departure: 17 May 2025
Countries Visited: Italy, France, Spain, Portugal
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$7,524
BALCONY
$8,811
SUITE
$8,118
Save (per person) 4,076
From (per person) 7,524
Cruise

11 Days (10 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Departure: 10 July 2026
Countries Visited: Italy, France, Spain, Gibraltar (+1 more), Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,579
SUITE
$15,093
Save (per person) 6,611
From (per person) 12,579
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Departure: 28 April 2026
Countries Visited: Italy, France, Spain, Morocco (+1 more), Portugal
Exclusive Deal
INSIDE
$7,464
OCEANVIEW
$9,029
BALCONY
$10,147
SUITE
$14,612
Save (per person) 2,056
From (per person) 7,464
Cruise

7 Days (6 Nights) Genoa to Lisbon
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 13 November 2024
Countries Visited: Italy, France, Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$1,065
SUITE
$2,025
From (per person) 1,065
Cruise

13 Days (12 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 November 2025
Countries Visited: Italy, Monaco, France, Spain (+1 more), Portugal
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,801
Save (per person) 2,599
From (per person) 9,801
Cruise

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Sojourn
Departure: 15 November 2026
Countries Visited: Italy, Corsica, Sardinia, Sicily (+6 more), Malta, Tunisia, Spain, Gibraltar, Morocco, Portugal
Earlybird Saving
INSIDE
-
OCEANVIEW
$12,885
BALCONY
$14,845
SUITE
$28,210
From (per person) 12,885
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Departure: 14 October 2025
Countries Visited: Italy, France, Spain, Portugal
More At Sea OfferExclusive Solo Offer
INSIDE
$3,238
OCEANVIEW
$3,590
BALCONY
$6,144
SUITE
$12,282
From (per person) 3,238
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Regent Seven Seas
Departure: 31 May 2025
Countries Visited: Italy, France, Spain, Morocco (+1 more), Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$21,018
Save (per person) 10,732
From (per person) 21,018
Cruise

15 Days (14 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 25 November 2026
Countries Visited: Italy, Malta, Sicily, Tunisia (+3 more), Sardinia, Spain, Portugal
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$10,098
BALCONY
$11,583
SUITE
$16,830
Save (per person) 2,602
From (per person) 10,098
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Norwegian Cruise Line
Departure: 25 June 2025
Countries Visited: Italy, France, Spain, Portugal
More At Sea Offer
INSIDE
$3,820
OCEANVIEW
$4,767
BALCONY
$7,368
SUITE
$14,193
From (per person) 3,820
Cruise

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Venture
Departure: 13 April 2025
Countries Visited: Italy, France, Spain, Morocco (+1 more), Portugal
SAIL INTO SAVINGS
INSIDE
-
OCEANVIEW
-
BALCONY
$16,226
SUITE
$16,226
From (per person) 16,226
Cruise

10 Days (9 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ships: Encore, Quest
Departures: Nov 2025 to Nov 2026
Countries Visited: Italy, Corsica, Sardinia, Spain (+1 more), Portugal
Earlybird Saving
INSIDE
-
OCEANVIEW
$6,471
BALCONY
$6,760
SUITE
$8,631
From (per person) 6,471
Cruise

17 Days (16 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Countries Visited: Italy, Sicily, Tunisia, Sardinia (+4 more), Spain, Gibraltar, Morocco, Portugal
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,553
From (per person) 14,553
Cruise

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Silversea
Ship: Silver Muse
Departure: 31 July 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+5 more), Sardinia, Spain, Gibraltar, Morocco, Portugal
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$18,216
BALCONY
$20,889
SUITE
$29,601
From (per person) 18,216
Results: 29 results

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